随着清洁能源的发展,风电作为一种清洁、可再生的能源,具有巨大的发展潜力。然而,风电的开发需要精确的风能资源测量和评估,以及选择适当的风电场址。因此,开发了基于B/S(Browser/Server,浏览器/服务器)端的风电场规划设计平台。该平台...随着清洁能源的发展,风电作为一种清洁、可再生的能源,具有巨大的发展潜力。然而,风电的开发需要精确的风能资源测量和评估,以及选择适当的风电场址。因此,开发了基于B/S(Browser/Server,浏览器/服务器)端的风电场规划设计平台。该平台提供了多种功能,包括项目管理、风能资源评估、风电场选址、中尺度数据处理和方案管理等。该平台利用GIS(Geographic Information System,地理信息系统)技术和模型计算方法,能够对风能资源进行多方面评估和分析,根据地理信息、环境和建设要求等因素,优化风电场选址。同时,该平台具有用户友好的界面和数据交互功能,使得开发者可以更加便捷地实现风电项目开发。实际应用结果表明,该平台在风电场选址、风电资源评估等方面具有较强的竞争力,能够有效促进风电产业的发展。展开更多
In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial cells.However,the functional role of GGT5 in the development of A...In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial cells.However,the functional role of GGT5 in the development of Alzheimer’s disease remains unclear.This study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying mechanism.We observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse model.Additionally,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive deficits.Interestingly,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 mice.This effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa B.Our findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 mice.These findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.展开更多
We characterize V modules by relative (quasi )continuity of left R modules in this paper. It is shown that a left R module M is a V module if and only if every finitely cogenerated left R ...We characterize V modules by relative (quasi )continuity of left R modules in this paper. It is shown that a left R module M is a V module if and only if every finitely cogenerated left R module in σ[M] is S ( quasi )continuous if and only if every left R module in σ[M] is S continuous, where S is the set of all simple left R modules. We also show that a left R module M is a locally noetherian V module if and only if every semisimple left R module (in σ[M]) is M injective if and only if every essential extension in σ[M] of every semisimple left R module in σ[M] is S ? 2 (quasi )continuous, where S ? 2 is the set of all semisimple left R modules.展开更多
In this paper,we focus on combining the theories of fuzzy soft sets with Γ-modules,and establishing a new framework for fuzzy soft Γ-submodules.The main contributions of the paper are 3-fold.First,we present the con...In this paper,we focus on combining the theories of fuzzy soft sets with Γ-modules,and establishing a new framework for fuzzy soft Γ-submodules.The main contributions of the paper are 3-fold.First,we present the concepts of（R,S）-bi-Γ-submodules,quasi-Γ-submodules and regular Γ-modules.Meanwhile,some illustrative examples are given to show the rationality of the definitions introduced in this paper.Second,several new kinds of generalized fuzzy soft Γ-submodules are proposed,and related properties and mutual relationships are also investigated.Third,we discover some intrinsic connections between the generalized fuzzy soft Γ-submodules presented in this paper and crisp Γ-submodules,and describe the relationships between regular Γ-modules and the generalized fuzzy soft Γ-submodules presented in this paper.展开更多
1.设计思路语言学习应以应用为目标,着重培养学生的交际能力,并能解决实际的生活问题。在目前的英语教学里,教师一般会在同一堂课里进行'听'与'说'的技能训练,其中'听'是'说'的前提,'说'是'...1.设计思路语言学习应以应用为目标,着重培养学生的交际能力,并能解决实际的生活问题。在目前的英语教学里,教师一般会在同一堂课里进行'听'与'说'的技能训练,其中'听'是'说'的前提,'说'是'听'的延伸。在听说课里,听力策略和会话技巧是帮助学生实现交流目的和信息沟通的桥梁,这也是教学设计的重点。2.教材分析本课的内容是牛津英语9B Module 2 Unit 3 The environment的听说课。展开更多
文摘随着清洁能源的发展,风电作为一种清洁、可再生的能源,具有巨大的发展潜力。然而,风电的开发需要精确的风能资源测量和评估,以及选择适当的风电场址。因此,开发了基于B/S(Browser/Server,浏览器/服务器)端的风电场规划设计平台。该平台提供了多种功能,包括项目管理、风能资源评估、风电场选址、中尺度数据处理和方案管理等。该平台利用GIS(Geographic Information System,地理信息系统)技术和模型计算方法,能够对风能资源进行多方面评估和分析,根据地理信息、环境和建设要求等因素,优化风电场选址。同时,该平台具有用户友好的界面和数据交互功能,使得开发者可以更加便捷地实现风电项目开发。实际应用结果表明,该平台在风电场选址、风电资源评估等方面具有较强的竞争力,能够有效促进风电产业的发展。
基金supported by STI2030-Major Projects,No.2021ZD 0201801(to JG)Shanxi Province Basic Research Program,No.20210302123429(to QS).
文摘In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial cells.However,the functional role of GGT5 in the development of Alzheimer’s disease remains unclear.This study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying mechanism.We observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse model.Additionally,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive deficits.Interestingly,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 mice.This effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa B.Our findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 mice.These findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.
文摘We characterize V modules by relative (quasi )continuity of left R modules in this paper. It is shown that a left R module M is a V module if and only if every finitely cogenerated left R module in σ[M] is S ( quasi )continuous if and only if every left R module in σ[M] is S continuous, where S is the set of all simple left R modules. We also show that a left R module M is a locally noetherian V module if and only if every semisimple left R module (in σ[M]) is M injective if and only if every essential extension in σ[M] of every semisimple left R module in σ[M] is S ? 2 (quasi )continuous, where S ? 2 is the set of all semisimple left R modules.
基金Supported by the National Natural Science Foundation of China (61175055)the Innovation Term of Higher Education of Hubei Province,China (T201109)+1 种基金the Natural Science Foundation of Hubei Province (2012FFB01101)the Natural Science Foundation of Education Committee of Hubei Province (D20131903)
文摘In this paper,we focus on combining the theories of fuzzy soft sets with Γ-modules,and establishing a new framework for fuzzy soft Γ-submodules.The main contributions of the paper are 3-fold.First,we present the concepts of（R,S）-bi-Γ-submodules,quasi-Γ-submodules and regular Γ-modules.Meanwhile,some illustrative examples are given to show the rationality of the definitions introduced in this paper.Second,several new kinds of generalized fuzzy soft Γ-submodules are proposed,and related properties and mutual relationships are also investigated.Third,we discover some intrinsic connections between the generalized fuzzy soft Γ-submodules presented in this paper and crisp Γ-submodules,and describe the relationships between regular Γ-modules and the generalized fuzzy soft Γ-submodules presented in this paper.
文摘1.设计思路语言学习应以应用为目标,着重培养学生的交际能力,并能解决实际的生活问题。在目前的英语教学里,教师一般会在同一堂课里进行'听'与'说'的技能训练,其中'听'是'说'的前提,'说'是'听'的延伸。在听说课里,听力策略和会话技巧是帮助学生实现交流目的和信息沟通的桥梁,这也是教学设计的重点。2.教材分析本课的内容是牛津英语9B Module 2 Unit 3 The environment的听说课。
