Modern biotechnology booms in the molecular life science. It brings about a promising future for improving human health, foodstuff, environment and energy and is of significance to improve traditional agriculture, dru...Modern biotechnology booms in the molecular life science. It brings about a promising future for improving human health, foodstuff, environment and energy and is of significance to improve traditional agriculture, druamakins and other展开更多
The Ca 2+-binding protein of the EF-hand type,S100B,exerts both intracellular and extracellular regulatory activities.As an intracellular regulator,S100B is involved in the regulation of energy metabolism,transcriptio...The Ca 2+-binding protein of the EF-hand type,S100B,exerts both intracellular and extracellular regulatory activities.As an intracellular regulator,S100B is involved in the regulation of energy metabolism,transcription,protein phosphorylation,cell proliferation,survival,differentiation and motility,and Ca 2+ homeostasis,by interacting with a wide array of proteins(i.e.,enzymes,enzyme substrates,cytoskeletal subunits,scaffold/adaptor proteins,transcription factors,ubiquitin E3 ligases,ion channels) in a restricted number of cell types.As an extracellular signal,S100B engages the pattern recognition receptor,receptor for advanced glycation end-products(RAGE),on immune cells as well as on neuronal,astrocytic and microglial cells,vascular smooth muscle cells,skeletal myoblasts and cardiomyocytes.However,RAGE may not be the sole receptor activated by S100B,the protein being able to enhance bFGF-FGFR1 signaling by interacting with FGFR1-bound bFGF in particular cell types.Moreover,extracellular effects of S100B vary depending on its local concentration.Increasing evidence suggests that at the concentration found in extracellular fluids in normal physiological conditions and locally upon acute tissue injury,which is up to a few nM levels,S100B exerts trophic effects in the central and peripheral nervous system and in skeletal muscle tissue thus participating in tissue homeostasis.The present commentary summarizes results implicating intracellular and extracellular S100B in tissue development,repair and regeneration.展开更多
This paper deeply studies the intelligent Home embedded system based on B/S architecture. Firstly, analysis requirement of Home function based on the existing software development mode, and proposed a system framework...This paper deeply studies the intelligent Home embedded system based on B/S architecture. Firstly, analysis requirement of Home function based on the existing software development mode, and proposed a system framework of intelligent Home system, and designed the communication scheme of the whole Home system, also gives the system each function module realization. This paper achieve two basic service system based on Intelligent Home through a series of analysis and design： outdoor remote intelligent Home monitoring service and the indoor intelligent management service.展开更多
This paper detailed describes the design of intelligent Home Furnishing system based on B/S architecture. According to the existing development mode of intelligent Home Furnishing system and the analysis of functional...This paper detailed describes the design of intelligent Home Furnishing system based on B/S architecture. According to the existing development mode of intelligent Home Furnishing system and the analysis of functional requirements, the paper puts forward the general framework of intelligent Home Furnishing system, and designed the communication scheme of the system, and gives the system each function module realization. This paper mainly completes the design of networking, each function module of embedded intelligent family gateway server in the system building and CGI intelligent interactive program and CGI interactive program. Experiments show that each function module of the system meet to design requirements, the overall system can satisfy the actual demand Home Furnishing user, validated the feasibility of the B/S architecture in intelligent Home Furnishing system.展开更多
A class of functions called quasi B s invex and pseudo B s invex functions are introduced by using the concept of symmetric gradient. The examples of quasi B s invex and pseudo B s invex functions are given. The suffi...A class of functions called quasi B s invex and pseudo B s invex functions are introduced by using the concept of symmetric gradient. The examples of quasi B s invex and pseudo B s invex functions are given. The sufficient optimality conditions and Mond Weir type duality results are obtained for a nondifferentiable nonlinear semi infinite programming problem involving quasi B s invex and pseudo B s invex functions.展开更多
Sustainable Development Goal(SDG 4)lays solid theoretical foundation for the development of higher teacher education in improving the quality of teaching faculty nationwide.Sustainable teacher training paves a way for...Sustainable Development Goal(SDG 4)lays solid theoretical foundation for the development of higher teacher education in improving the quality of teaching faculty nationwide.Sustainable teacher training paves a way for teacher professional development in the long run.China’s“National Teacher Training Program”serves a connection between higher teacher education and K-12 teachers in multiple perspectives when exploring K-12 teachers’improvement of the essence by upgrading the initiative of the program with the assistance of educational technology and modern educational philosophy from mutual creation to mutual benefit.Direction orientation strategic design based on demand for teaching faculty,curriculum setting in modules,and characteristics creation have been carried out to upgrade the training of teacher colleges and National Teacher Training Program in the future for achieving a win-win situation between higher teacher education and K-12 education.展开更多
文摘Modern biotechnology booms in the molecular life science. It brings about a promising future for improving human health, foodstuff, environment and energy and is of significance to improve traditional agriculture, druamakins and other
基金Supported by Ministero dell'Università e della Ricerca,No. PRIN 2007LNKSYS,No.2007AWZTHH_004 and No.2009WBFZYM_002Association Fran aise contre les Myopathies,No. Project 12992+1 种基金Associazione Italiana per la Ricerca sul Cancro,No. Project 6021Fondazione Cassa di Risparmio di Perugia,No. 2007.0218.020,No.2009.020.0021 and No.2012.0241.021
文摘The Ca 2+-binding protein of the EF-hand type,S100B,exerts both intracellular and extracellular regulatory activities.As an intracellular regulator,S100B is involved in the regulation of energy metabolism,transcription,protein phosphorylation,cell proliferation,survival,differentiation and motility,and Ca 2+ homeostasis,by interacting with a wide array of proteins(i.e.,enzymes,enzyme substrates,cytoskeletal subunits,scaffold/adaptor proteins,transcription factors,ubiquitin E3 ligases,ion channels) in a restricted number of cell types.As an extracellular signal,S100B engages the pattern recognition receptor,receptor for advanced glycation end-products(RAGE),on immune cells as well as on neuronal,astrocytic and microglial cells,vascular smooth muscle cells,skeletal myoblasts and cardiomyocytes.However,RAGE may not be the sole receptor activated by S100B,the protein being able to enhance bFGF-FGFR1 signaling by interacting with FGFR1-bound bFGF in particular cell types.Moreover,extracellular effects of S100B vary depending on its local concentration.Increasing evidence suggests that at the concentration found in extracellular fluids in normal physiological conditions and locally upon acute tissue injury,which is up to a few nM levels,S100B exerts trophic effects in the central and peripheral nervous system and in skeletal muscle tissue thus participating in tissue homeostasis.The present commentary summarizes results implicating intracellular and extracellular S100B in tissue development,repair and regeneration.
文摘This paper deeply studies the intelligent Home embedded system based on B/S architecture. Firstly, analysis requirement of Home function based on the existing software development mode, and proposed a system framework of intelligent Home system, and designed the communication scheme of the whole Home system, also gives the system each function module realization. This paper achieve two basic service system based on Intelligent Home through a series of analysis and design： outdoor remote intelligent Home monitoring service and the indoor intelligent management service.
文摘This paper detailed describes the design of intelligent Home Furnishing system based on B/S architecture. According to the existing development mode of intelligent Home Furnishing system and the analysis of functional requirements, the paper puts forward the general framework of intelligent Home Furnishing system, and designed the communication scheme of the system, and gives the system each function module realization. This paper mainly completes the design of networking, each function module of embedded intelligent family gateway server in the system building and CGI intelligent interactive program and CGI interactive program. Experiments show that each function module of the system meet to design requirements, the overall system can satisfy the actual demand Home Furnishing user, validated the feasibility of the B/S architecture in intelligent Home Furnishing system.
基金the Natural Science Foundation of Shaanxi Province and the Science Foundation of Shaanxi Provincial Educational CommitteeP.R.China
文摘A class of functions called quasi B s invex and pseudo B s invex functions are introduced by using the concept of symmetric gradient. The examples of quasi B s invex and pseudo B s invex functions are given. The sufficient optimality conditions and Mond Weir type duality results are obtained for a nondifferentiable nonlinear semi infinite programming problem involving quasi B s invex and pseudo B s invex functions.
文摘Sustainable Development Goal(SDG 4)lays solid theoretical foundation for the development of higher teacher education in improving the quality of teaching faculty nationwide.Sustainable teacher training paves a way for teacher professional development in the long run.China’s“National Teacher Training Program”serves a connection between higher teacher education and K-12 teachers in multiple perspectives when exploring K-12 teachers’improvement of the essence by upgrading the initiative of the program with the assistance of educational technology and modern educational philosophy from mutual creation to mutual benefit.Direction orientation strategic design based on demand for teaching faculty,curriculum setting in modules,and characteristics creation have been carried out to upgrade the training of teacher colleges and National Teacher Training Program in the future for achieving a win-win situation between higher teacher education and K-12 education.
