Study on the interaction between polymorphisms of FOXO3A gene and environmental factors in longevity at Bama county,Guangxi province

Objective: To study the interaction between the polymorphisms of FOXO3A and the environmental factors in the longevity district of Bama county.Methods: Using Taqmaq probe,genotyping of FOXO3A gene was performed for 200 longevous elderly(aged 90-110)and 288 healthy controls(aged 48-89).The interaction between the polymorphisms of gene and environmental factors were analyzed by using conditional logistic regression.Results: Minor allele frequencies(MAF)of five known SNPs in FOXO3A gene were higher in cases than in controls(P<0.05).There was a positive interction between minority alleles of rs2764264 in FOXO3A gene and the environment factors in the longevity district(OR=11.08,γ=1.075).Conclusion: Five SNPs of FOXO3A gene would be closely correlated with human longevity in Bama.The interaction between the polymorphisms of FOXO3A genes rs2764264 and the environment factors in the longevity district had synergy to longevity.The longevity phenomenon in Bama probably was the result of the interaction between gene and environmental factors.

Cloning and Sequence Analysis of Adiponectin Receptor 1 and Receptor 2 cDNA from Guangxi Bama Mini-pig

[ Objective] To clone and analyze the sequence of Adiponectin receptor 1 （ AdipoR1 ） and receptor 2 （AdipoR2） cDNA of Guangxi Bama mini-pig. [Method] The Adiponectin receptors cDNAs were amplified by RT-PCR using skeletal muscle total RNA as template and then ligated into pMD18-T vector after purification. The recombinant pMD18-T vector was transformed into the E. coil DH5α for identification and sequencing. And the results were compared with the cDNA sequence from other species. [Result] The fragments, 1 128 bp and 1 161 bp in size, were amplified by RT-PCR and respectively consistent with the coding sequence of AdipoR1 gene and AdipoR2 gene. The homology analysis showed that the sequences of AdipoR1 gene and AdipoR2 gene were respectively 99.8% and 99.7% homologous to the sequence of domestic pig reported in GenBank with one base and three base missense mutations correspondingly. [ Conclusion] The AdipoR1 gene and AdipoR2. gene were successfully amplified from Guangxi Bama mini-pig, laying the foundation for the further study of the biological function of AdipoR genes and the design of novel drugs with AdipoR as target.

Present situation and the countermeasures of health human resources in Guangxi general hospitals at the county - level

[目的] 了解广西县级综合医院卫生人力资源状况,为进一步推进县级医院改革提供建设性意见. [方法]通过问卷调查法、数理统计法等综合分析广西县级综合医院卫生人力资源现状.[结果]广西县级综合 医院在岗人员在编率为41.56%,医护比为1： 1.68, 67.12%的卫生技术人员职称为初级及以下,超七成拥有 大专及以上学历.[结论]广西县级综合医院卫生技术人员在编率较低,医护比、职称及学历结构不合理,整 体年龄偏低,需通过综合措施加以改善.

Update of Cultivated Land Quality Grade Based on GIS—A Case Study of a County in Guangxi

The quality of cultivated land has an important influence on agricultural output, food security, sustainable development and the ability of using cultivated land resources. As the trend of cultivated land quality is getting more and more attention, in order to strengthen the management of cultivated land quality, improve the precision of cultivated land quality and other achievements, and maintain the current situation of cultivated land quality and other achievements. For this paper, taking A county of Guangxi Zhuang Autonomous Region as an example, with the support of GIS, the paper studies the grade and grade renewal of cultivated land by using the superposition method, studies the grade and grade change of regional cultivated land and its spatial distribution, grasps the status quo change of cultivated land and the grade and grade change of cultivated land caused by the quality construction of cultivated land in the year, and then provides scientific data for land use plan, land consolidation and cultivates land protection.

SUSTAINABLE USE OF LAND RESOURCE AND ITS EVALUATION IN COUNTY AREA—A Case of Guangxi Zhuang Autonomous Region, China

Sustainable use of natural resources is different from sustainable development. As the most important natural resource, sustainable use of land resource is the essential guarantee of sustainable development. The nature of sustainable use of land resource is to retain the quantity and productivity of land resource from generation to generation.The evaluation of sustainable use of land resource is an important method to ensure land use to get onto the sustainable track. Furthermore, building index system is the key of the evaluation. In view of tendency of the evaluation indexes chosen so widely, the evaluation indexes should include only three kinds in the researches on the evaluation of sustainable use of land resource. The first is the stock and structure index of land resource, viz. Areas quantity structure of land resources. In China, it is especially paid attention to the per person index of land quantity and rate between cultivated land and farmland. The second is the productive index of land, which includes the productivity, potentiality, stability and renewal situation of land. The third is the sustained index of land environment. On the evaluation research of area level, we should lay particular emphasis on statistic indexes. With a case of Guangxi Zhuang Autonomous Region in China, the evaluation index system of sustainable land use in county area has been built in this thesis. Using the weighted average method to calculate the means of sustainable land use in each county, according to the land using situation, all counties in the autonomous region have been divided into three types. (1) Sustainable Pattern contains 18 counties, which have higher land resource productivity, stronger sustained abilities of land environment .The economic benefits of land using in these counties are obviously higher. These counties have gotten highly intensive farming, and they are all in the good circumstance. (2) Basically Sustained Pattern contains 48 counties, which productivity of land resource is of middle level. In part of counties and cities, the stock of land resource inclines to lower level, but their land using potentialities are still greater. Through changing land using pattern, these counties can rapidly enter in a good circumstance. (3) Critically Sustained Pattern contains 14 counties, which are mostly in the karst mountain areas. They have less stock of land resource, lower productivity and more extensive cultivation. The productivity of land renewing has been hindered, so it urgently need to be renovated. At last, the writers have explored the basic ways of sustainable use of land resource in Guangxi, China — (1) Retain the stock of land resource and strictly manage farmland uses. (2) Strengthen the value accounting of land resource, and control the farmland occupation of non agricultural construction. (3) Depend on technology advanced, optimize the land using structure, and promote the productive level. (4) Carry out land management all round, and improve the ecological environment of land resource. (5) Enhance evaluation researche and land monitoring, and promote the sustainable utilization level of land resource.

Correlation between the Polymorphism of PPARγ-2 gene and the Susceptibility of Type 2 Diabetes Mellitus in Guangxi Bama Mini-pigs

[ Objective] The research aimed to discuss the relationship between the polymorphism of PPARy.2 gene and the susceptibility of type 2 diabetes mellitus （T2DM） in Guangxi Bama mini-pigs. [ Method] 24 Guangxi Bama mini-pigs were fed with high-fat and high-sucrose diet, and partial sequences of exon 2 of PPARy-2 gene were amplified by using PCR method. In addition, the contents of fasting blood glucose and insulin （INS） in Guangxi Bama mini-pigs were determined, and the glucose tolerance test （GTT） was also carried out. [ Result] There was one SNP site （19813A/G） Jn partial sequence of exon 2 of the cloned PPAFly-2 gene, and AA （7 pigs） and AG （17 pigs） genotype were detected. The contents of fasting insulin and 60-min blood glucose in GTT in AG-genotype Guangxi Bama mini-pigs were significantly higher than those of AA genotype （ P 〈0.05）, while the incidence of T2DM in AG-genotype Guangxi Bama mini-pigs （71.4%） was obviously higher than that of AA gen- otype （5.9%）. [ Conclusion] The polymorphism of 19813A/G in exon 2 of PPARy-2 gene was related with the susceptibility of T2DM in Guangxi Bama mini-pigs.

A Basal Titanosauriform from the Early Cretaceous of Guangxi, China

Based on a partial postcranial skeleton collected from the Lower Cretaceous Napai Formation of Guangxi, China, we erect a new sauropod taxon, Fusuisaurus zhaoi gen. et sp. nov. The holotype specimen consists of the left ilium, left pubis, anterior caudals, most of the dorsal ribs and distal end of the left femur. Fusuisaurus zhaoi is diagnosed by a unique combination of character states among the known sauropods. It displays several synapomorphies of Titanosauriformes but lacks many derived features seen in other titanosauriforms, suggesting that the new taxon represents the basalmost known titanosauriform and providing new evidence that Titanosauriformes originated from Asia. A size comparison suggests that Fusuisaurus zhaoi is among the largest Early Cretaceous sauropods, providing an important addition to the Early Cretaceous Chinese sauropod diversity.

Bama County: A Land of Longevity

Bama County。in the Guangxi Zhuang Autonomous Region in South China.is well known for a longer meanage of its population in China and the world over.It is called a 1and of longevity,and there are at present 66 centenarians in the county.

巴马小型猪仰卧位的新型固定方法

目的 研究广西巴马小型猪仰卧位的固定方法以便于动物实验的开展。方法 选择行胸腔器官获取的广西巴马小型猪12头,接受全身麻醉后采用专用的固定装置进行仰卧位固定。结果 12头广西巴马小型猪在手术中体位得到很好的保持,未发生侧翻、移位等现象。结论 采用专用的固定装置对广西巴马小型猪进行仰卧位固定是一种简单有效的方法。

广西边境地区县域卫生资源配置状况研究

目的分析广西边境地区县域卫生资源配置现状及其公平性,为优化县域卫生资源配置提供参考。方法收集广西边境地区8个县域2015—2021年的卫生资源数据,从人口、地理两个维度评价县域卫生资源配置的公平性。结果2015—2021年,广西边境地区8个县域的卫生资源总体呈逐年增加的趋势,但大部分县域千人口床位数、执业(助理)医师数、注册护士数低于广西平均水平;按人口配置的各类卫生资源公平性的基尼系数优于按地理配置的。结论应强化政府在卫生资源配置中的宏观调控功能,进一步提高广西边境地区卫生资源配置水平;加大边境地区县域卫生人力资源投入力度,持续提升卫生人力资源供给能力;多措并举,稳定边境地区村卫生室人员队伍;优化边境地区县域卫生资源空间布局,保障卫生资源配置的公平性。

丘陵地区重要集镇预警雨量值计算技术研究——以广西巴马县燕洞镇为例

预警雨量值计算是山洪灾害防治非工程措施中的重要环节。为研究丘陵地区重要集镇预警雨量值计算方法,选取广西巴马县燕洞镇作为典型区域,通过设计暴雨、设计洪水、水位流量关系转换等方法,确定了预警时段、预警阈值等关键结论。

农业科研院所科技支撑农业科技现代化先行县建设的实践与思考——以广西农业科学院共建先行县为例

在农业农村部科学技术司公布的全国农业科技现代化先行县共建名单中,包含广西农业科学院(对口技术单位)与富川瑶族自治县(共建先行县),二者共同开展农业科技现代化先行县共建工作。文章介绍了广西农业科学院以科技支撑农业科技现代化先行县建设发展的经验做法、取得的主要成效,分析了先行县共建工作中存在的问题,并针对问题提出了压实先行县共建工作责任、多渠道筹资保障先行县共建工作需要、加强共建工作宣传引导、深化院县合作等进一步优化先行县共建工作的建议,以期为对口技术单位进一步做好先行县建设工作提供参考。

广西天峨主要耕地区农作物中重金属元素富集特征与影响因素

重金属污染制约着农产品安全问题,本文选择广西天峨县为研究切入点,以揭示农作物中重金属元素生态风险情况。系统采集60套水稻和玉米样品以及根系土壤样品,测试Cd、Cr、Hg、As和Pb等5种重金属元素含量,采用地累积指数、生物富集系数及相关性分析等方法进行数据处理。研究结果表明:除了Hg之外,其它重金属元素Cd、Cr、As和Pb含量均未超标,属于食品安全范围;其中Cr含量最高,平均值为0.094 mg/kg,而Cd含量变异系数极大,高达103%;水稻籽实中Cd、Hg和As等重金属含量普遍高于玉米籽实。根系土壤处于酸性环境,有机质养分较丰富,并存在中等程度Cd污染情况;重金属形态绝大多数为残渣态,其中Cd离子活性较高。农作物对Cd和Hg具有较强的富集能力,碎屑岩区土壤中重金属的生物富集系数高于碳酸盐岩区。经相关性分析表明,水稻中Hg含量与根系土壤中Cd含量呈极显著正相关关系,同时土壤酸碱度及有机质是影响农作物中重金属元素含量的重要因素。因此,适当调整土壤酸性程度、合理增施有机肥料,能够有效控制重金属污染风险,这对保障农产品安全具有基础性意义。

乡村振兴背景下事业单位类型新型研发机构发展现状案例分析——以巴马瑶族自治县乡村振兴研究院为例

为了探究事业单位类型新型研发机构在乡村振兴背景下利用科技创新助力乡村振兴的积极作用,文章以中国农业科学院深圳农业基因组研究所和巴马瑶族自治县人民政府共同创建的新型研发机构——巴马瑶族自治县乡村振兴研究院为例,详细介绍了该机构的建设背景、科技支持案例,分析了该机构目前的发展状况和面临的挑战,并从增强科技成果转化意识、健全科技人才激励机制、促进自身供血体系建设等方面提出了建议,旨在为事业单位类型新型研发机构的发展提供参考和借鉴,推动其更好地服务于乡村振兴事业。

广西壮族自治区乡镇及区县尺度社会经济及环境数据集

广西壮族自治区地处中国西南,拥有丰富的自然生态资源和多元的社会和文化背景,在省(区)域范围开展可持续发展研究,离不开时空尺度更为精准的乡镇及区县尺度社会经济和环境数据的支持。本研究获取了多种来源的环境要素数据、基础设施及工农业生产相关数据,通过参数提取、乡镇边界矢量和环境参数、基础设施及工农业生产相关栅格数据叠加运算,构建了1241个乡镇单元的环境参数数据、基础设施及工农业生产相关数据,同时基于广西统计局发布的广西统计年鉴,制备广西111个区县的社会经济数据,最终形成广西壮族自治区乡镇及区县尺度社会经济及环境数据集。数据处理过程不对原始数据构成精度损失,经多人复核审查,其数据完整性、位置精度、属性精度等均符合有关技术规定和标准的要求。本数据集为时间序列长、参数类型多的公开参数,数据集的参数维度、时空维度均可拓展,为区域多尺度的可持续发展提供了数据支持。

中华眼镜蛇毒致广西巴马小型猪坏死组织渗出液中的蛇毒成分分析

目的:探究中华眼镜蛇毒致广西巴马小型猪坏死组织渗出液中的蛇毒成分及其蛋白表达的动态变化。方法:给予广西巴马小型猪注射中华眼镜蛇毒,构建蛇伤中毒的局部组织坏死模型,在注射毒素后的6 h、12 h、24 h、36 h和48 h取小猪坏死组织的渗出液,采用无标记的蛋白质组学技术鉴定分析渗出液中蛇毒蛋白质组成及动态变化,通过对所鉴定出的蛋白进行KEGG及GO通路富集分析,以深入了解蛇毒蛋白相关的生物学功能。结果:通过蛇伤中毒后广西巴马小型猪的生物学行为、局部肌肉组织的病理结果、注射部位的伤口变化来评判动物模型,广西巴马小型猪中毒后出现呼吸急促、肌肉组织坏死、局部伤口溃烂等症状,均符合临床特征的实际情况,表明成功构建了中华眼镜蛇毒导致局部组织坏死的广西巴马小型猪模型。在广西巴马小型猪的局部组织坏死渗出液中鉴定到40种蛇毒蛋白质,涵盖三指毒素、磷脂酶A2、富含半胱氨酸分泌蛋白、蛇毒金属蛋白酶、核苷酸焦磷酸/磷酸二酯酶等蛇毒蛋白家族,并呈现出动态性数量变化。结论:在中华眼镜蛇毒致广西巴马小型猪过程中,不同时间段的组织渗出液中均鉴定出多种三指毒素、磷脂酶A2等蛇毒蛋白,其可能在局部组织坏死中发挥着重要作用。

广西南丹白裤瑶服饰纹样研究

白裤瑶服饰纹样作为白裤瑶民族文化的符号与载体,蕴含着丰富的文化遗产。文中对白裤瑶相关的社会概况、图腾信仰、服饰文化、服饰纹样方面的研究动态进行调研,从艺术学的角度对白裤瑶服饰纹样进一步深入研究,整理归纳白裤瑶服饰纹样类型、装饰部位及其寓意,分析白裤瑶服饰纹样的色彩、造型、形式审美。以期推动白裤瑶传统文化的传承与发展,并为后续白裤瑶族服饰文化的相关研究工作提供参考。

桂西南石漠化综合治理效益评价及其耦合协调关系

为探究国家启动石漠化综合治理试点工程以来的成效,基于县域尺度,通过构建指标体系综合评估2010、2015和2020年桂西南石漠化治理的生态、经济和社会效益变化情况,并利用耦合协调度模型探究各县(区)石漠化治理效益间的耦合协调程度,以解析影响耦合协调性提升的限制因素。结果表明:(1)2010-2020年间桂西南石漠化治理效益指数排序为:生态效益>社会效益>经济效益,其中生态效益提升幅度最大,社会效益缓慢增长,经济效益提升速度有所降低,总体呈良性发展态势;(2)研究区石漠化治理成效状况存在差异,西北部及中部区域保持较高生态效益,而经济效益和社会效益较高值区主要分布在东南部“强首府战略”背景下的南宁市主城区及所辖宾阳县、横州市等区域;(3)“生态-经济-社会”效益三者耦合协调度均值在0.47~0.51之间,处于濒临失调和勉强协调状态;2020年各县(区)石漠化治理效益的耦合协调关系表现出不同程度的滞后现象,经济、社会效益滞后是制约石漠化治理效益耦合协调提升的关键因子。在后续的石漠化治理中,既要注重生态环境保护,也要加快经济社会高质量发展。

桂北龙胜浅变质碎屑岩中金矿属于造山型金矿

桂北地区金矿资源丰富,已发现金矿床(点)70多处,但面临“只见星星不见月亮”的尴尬处境。2020~2022年,申请者及其团队对桂北龙胜大地金矿开展普查、详查工作,矿床规模达到中型以上,是桂北金矿找矿重要的窗口和突破口。桂北龙胜地区位于江南造山带的西南端,是湘黔桂金三角重要组成部分。近年来,在黔东南和湘西地区陆续发现造山型金矿(文静等,2022;陈军等,2023)。

广西农业经济增长的时空特征与影响因素研究——基于96个县域面板数据的空间计量分析

探究县域农业经济增长的空间特征及其影响因素,对促进广西县域经济协调发展意义重大。基于广西96个县域的面板数据,采用ESDA分析法分析广西农业经济增长的时空演变特征,构建空间杜宾模型深入剖析广西农业经济增长的影响因素及其空间效应,并分区域考察各影响因素对农业经济增长的贡献差异。结果表明:广西县域农业经济增长整体表现出较强的空间相关性,局部空间关联存在明显的“高—高”和“低—低”空间集聚特征;各投入要素对农业经济增长的影响存在较大差异,且空间效应以正向为主,土地、农业技术和政府资本等要素投入每增加1%,将分别带来农业经济增长水平提高0.706%、0.994%、0.108%;广西5大内部区域农业经济增长的主要影响因素及其影响程度存在明显差异,空间效应也存在明显的区域差异。基于研究结论得出政策启示:加强相邻县域之间农业发展的区域协同性,并努力缩减县域之间农业经济增长差距;各内部区域应有针对性地提升农业投入水平,遵循相对比较优势原则,通过增加农业要素投入促进农业经济增长。