The Beila ophiolite is located in the middle part of the Bangong-Nujiang suture zone,northern Tibetan plateau.It is a complete ophiolite suite,and plays a key role in understanding the evolution of the Bangong-Nujiang...The Beila ophiolite is located in the middle part of the Bangong-Nujiang suture zone,northern Tibetan plateau.It is a complete ophiolite suite,and plays a key role in understanding the evolution of the Bangong-Nujiang suture zone,as well as the Meso-Tethys Ocean.The Beila ophiolite was composed of peridotite,serpentinite,gabbro,pillow basalt,and minor rodingite.Peridotites comprisemainlymedium–tocoarse–grained serpentinized harzburgites and minor plagioclase-bearing lherzolites and dunites.There are some felsic-ultramafic dykes within the peridotite and they are mainlypegmatoidal pyroxenites,coarse to fine-grained gabbros,and diabases.Gabbros included isotropic and cumulate gabbros,and they commonly contain minor pegmatoidal gabbros veins.Pillow basalts and basaltic andesites overlaid on the margin of the serpentinized peridotites.Rodingite occurs as lenses and/or dykes within the host serpentinized peridotites.Zircon SHRIMP U–Pb dating for two rodingite samples yielded the ages ranging from172 to 164 Ma.Whole-rock geochemical and zircon Hf isotopic data show that the Beila ophiolite shows SSZ-type ophiolite affinity.Finally,we suggest that the Beila ophiolite was generated in an initial subduction process at the middle Jurassic(164–172 Ma).展开更多
Yongzhu–Guomang Lake ophiolitic melange exposed about 100 km with large scale and complete ophiolitic uint in Xainza County,Xizang(Tibet).It is connected with Nam Lake,Kaimeng ophiolitic mélange to the east,and
There is a long-term dispute at Moho depth across the Bangong-Nujiang suture (BNS). Due to the complicated and changeable seismic geological condition, it is not easy to acquire images of the reflective Moho in centra...There is a long-term dispute at Moho depth across the Bangong-Nujiang suture (BNS). Due to the complicated and changeable seismic geological condition, it is not easy to acquire images of the reflective Moho in central Tibet. In the support of the SinoProbe project, a series of deep seismic reflection profiles were conducted to image Moho structure across the BNS and the Qiangtang terrane. These profiles extend from the northern Lhasa terrane to the Qiangtang terrane crossing the BNS. Both shot gathers and migration data show clear Moho images beneath the BNS. The Moho depth varies from 75.1 km (~24 s TWT) beneath the northmost Lhasa terrane to 68.9 km (~22 s TWT) beneath southmost Qiangtang terrane, and rises smoothly to 62.6 km (~20 s TWT ) at ~28 km north of the BNS beneath the Qiangtang terrane. We speculate that the Moho appears a 6.2 km sharp offset across the BNS and becomes ~12.5 km shallower from the northmost Lhasa terrane to the south Qiangtang terrane at ~28 km north of the BNS. The viewpoint of Moho depth across the BNS based on deep seismic reflection data is inconsistent with the previous 20 km offset.展开更多
The ophiolite-bearing Bangong-Nujiang zone (BNZ) traversing central Tibet from east to west separates the Qiangtang block in the north from the Lhasa block in the south. The Cretaceous of the area includes Chuanba For...The ophiolite-bearing Bangong-Nujiang zone (BNZ) traversing central Tibet from east to west separates the Qiangtang block in the north from the Lhasa block in the south. The Cretaceous of the area includes Chuanba Formation (K 1c ), Duoba Formation (K 1d ), Langshan Formation (K 1l ) and Jiangba Formation (K 2j ). The K 1c is composed of black shale, sandy pelite, siltstone, sandstone, coal beds and volcanic rocks, of shallow marine facies. The K 1 d consists of terrestrial siliciclastics intercalated with some calcareous sandstone beds bearing Orbitolina sp. indicating marine influence. The K 1j is carbonate platform deposits of shallow marine and lagoon. The K 2j is characterized by terrestrial thick massive red conglomerate. An active margin related to B-subduction zone is considered to be the geological setting of the Cretaceous sedimentation.展开更多
BACKGROUND Endoscopic full-thickness resection(EFTR)of gastric submucosal tumors(SMTs)is safe and effective;however,postoperative wound management is equally important.Literature on suturing following EFTR for large(...BACKGROUND Endoscopic full-thickness resection(EFTR)of gastric submucosal tumors(SMTs)is safe and effective;however,postoperative wound management is equally important.Literature on suturing following EFTR for large(≥3 cm)SMTs is scarce and limited.AIM To evaluate the efficacy and clinical value of double-nylon purse-string suture in closing postoperative wounds following EFTR of large(≥3 cm)SMTs.METHODS We retrospectively analyzed the data of 85 patients with gastric SMTs in the fundus of the stomach or in the lesser curvature of the gastric body whose wounds were treated with double-nylon purse-string sutures after successful tumor resection at the Endoscopy Center of Renmin Hospital of Wuhan University.The operative,postoperative,and follow-up conditions of the patients were evaluated.RESULTS All tumors were completely resected using EFTR.36(42.35%)patients had tumors located in the fundus of the stomach,and 49(57.65%)had tumors located in the body of the stomach.All patients underwent suturing with double-nylon sutures after EFTR without laparoscopic assistance or further surgical treatment.Postoperative fever and stomach pain were reported in 13(15.29%)and 14(16.47%)patients,respectively.No serious adverse events occurred during the intraoperative or postoperative periods.A postoperative review of all patients revealed no residual or recurrent lesions.CONCLUSION Double-nylon purse-string sutures can be used to successfully close wounds that cannot be completely closed with a single nylon suture,especially for large(≥3 cm)EFTR wounds in SMTs.展开更多
In this study,zircon U-Pb dating of volcanic rocks from the Zhongba ophiolite of the Yarlung Zangbo Suture Zone(YZSZ)in southern Xizang(Tibet)yielded an age of 247±3 Ma.According to whole rock geochemical and Sr-...In this study,zircon U-Pb dating of volcanic rocks from the Zhongba ophiolite of the Yarlung Zangbo Suture Zone(YZSZ)in southern Xizang(Tibet)yielded an age of 247±3 Ma.According to whole rock geochemical and Sr-NdPb isotopic data,the Early Triassic samples could be divided into two groups:Group 1 with P-MORB affinity,showing initial^(87)Sr/^(86)Sr ratios of 0.70253–0.70602,ε_(Nd)(t)values of 4.2–5.3,(^(206)Pb/^(204)Pb)_(t)ratios of 16.353–18.222,(^(207)Pb/^(204)Pb)_(t)ratios of 15.454–15.564,and(^(208)Pb/^(204)Pb)_(t)ratios of 35.665–38.136;Group 2 with OIB affinity,showing initial^(87)Sr/^(86)Sr ratios of 0.70249–0.70513,ε_(Nd)(t)values of 4.4–4.9,(^(206)Pb/^(204)Pb)_(t)ratios of 17.140–18.328,(^(207)Pb/^(204)Pb)_(t)ratios of 15.491–15.575,and(^(208)Pb/^(204)Pb)_(t)ratios of 36.051–38.247.Group 2 rocks formed by partial melting of the mantle source enriched by a former plume,and assimilated continental crustal material during melt ascension.The formation of Group 1 rocks corresponds to the mixing of OIB melts,with the same components as Group 2 and N-MORBs.The Zhongba Early Triassic rocks belong to the continental margin type ophiolite and formed in the continental–oceanic transition zone during the initial opening of the Neo-Tethys in southern Xizang(Tibet).展开更多
Precise orchestration of cell fate determination underlies the success of scaffold-based skeletal regeneration.Despite extensive studies on mineralized parenchymal tissue rebuilding,regenerating and maintaining undiff...Precise orchestration of cell fate determination underlies the success of scaffold-based skeletal regeneration.Despite extensive studies on mineralized parenchymal tissue rebuilding,regenerating and maintaining undifferentiated mesenchyme within calvarial bone remain very challenging with limited advances yet.Current knowledge has evidenced the indispensability of rebuilding suture mesenchymal stem cell niches to avoid severe brain or even systematic damage.But to date,the absence of promising therapeutic biomaterials/scaffolds remains.The reason lies in the shortage of fundamental knowledge and methodological evidence to understand the cellular fate regulations of scaffolds.To address these issues,in this study,we systematically investigated the cellular fate determinations and transcriptomic mechanisms by distinct types of commonly used calvarial scaffolds.Our data elucidated the natural processes without scaffold transplantation and demonstrated how different scaffolds altered in vivo cellular responses.A feasible scaffold,polylactic acid electrospinning membrane(PLA),was next identified to precisely control mesenchymal ingrowth and self-renewal to rebuild non-osteogenic suture-like tissue at the defect center,meanwhile supporting proper osteointegration with defect bony edges.Especially,transcriptome analysis and cellular mechanisms underlying the well-orchestrated cell fate determination of PLA were deciphered.This study for the first time cellularly decoded the fate regulations of scaffolds in suture-bony composite defect healing,offering clinicians potential choices for regenerating such complicated injuries.展开更多
Dear Editor,We described an innovative“single self-leading suture technique”for repairing iridodialysis.Instead of moving the needle forth and back,our method is easier to manipulate in the narrow surgical space bet...Dear Editor,We described an innovative“single self-leading suture technique”for repairing iridodialysis.Instead of moving the needle forth and back,our method is easier to manipulate in the narrow surgical space between the cornea and lens,which will decrease the unnecessary complications related to iatrogenic injury.We provide an economical friendly and less time-taking method,which improves the suture accuracy.展开更多
AIM:To report a technique used with intermittent slidinglock-knot(ISLK)fixation for limbal conjunctival autografts in pterygium surgery and compared with those of routine intermittent(RI)fixation.METHODS:Consecutive p...AIM:To report a technique used with intermittent slidinglock-knot(ISLK)fixation for limbal conjunctival autografts in pterygium surgery and compared with those of routine intermittent(RI)fixation.METHODS:Consecutive patients with primary pterygium who had undergone pterygium excision combined with limbal conjunctival autograft transplantation between March 2021 and March 2022 at our institute were retrospectively analyzed.Primary outcome measures were mean duration of surgery and suture removal,degree of conjunctival hyperemia on postoperative day 1,pain score at suture removal,postoperative symptoms at 6mo,including conjunctival hyperemia,foreign body sensation,and graft stability.RESULTS:Ninety-eight patients underwent monocular surgery and were divided into ISLK(51 eyes)and RI(47 eyes)groups according to the type of conjunctiva autograft fixation method planned.There was no significant difference in mean duration of surgery between the two groups(18.59±2.39min vs 18.15±2.20min,P=0.417);however,compared to the RI group,shorter suture removal times were observed in the ISLK group[0.58min(0.42-0.87)vs 3.00min(2.21-4.15),P<0.001].The degree of conjunctival hyperemia on postoperative day 1 was milder in the ISLK group(P<0.001).Pain scores at suture removal were lower in the ISLK group than in RI group[1(0-3)vs 2(1-4),P<0.001].Postoperative symptoms at 6mo were comparable between the groups(P=0.487),with no recurrence.CONCLUSION:ISLK is an innovative method for limbal conjunctival autograft fixation after pterygium excision.Compared to RI fixation,ISLK facilitates suture removal and reduces discomfort,with comparable surgery duration and less conjunctival hyperemia.展开更多
Objective:Double-J(DJ)ureteric stents are commonly placed perioperatively for semirigid or flexible ureteroscopic renal surgery.It is believed that lesser stent material within the bladder mitigates stent-related symp...Objective:Double-J(DJ)ureteric stents are commonly placed perioperatively for semirigid or flexible ureteroscopic renal surgery.It is believed that lesser stent material within the bladder mitigates stent-related symptoms.This study aimed to evaluate the J-Fil ureteral stent,a single pigtail suture stent compared with conventional DJ stent in relation to stent symptoms in an Asian population undergoing ureterorenal intervention.Methods:Based on internal audit committee recommendation approval,the records of 50 patients retrieved,available data of 41 patients who were prospectively enrolled into two groups(Group 1[J-Fil stent group],n=21 and Group 2[DJ stent group],n=20)between August 2020 to January 2021,were analysed.Parameters compared were nature of procedure,stone location and size,ease of deployment or removal,and complications.A modified universal stent symptom questionnaire was used to assess morbidity of stent symptoms within 48 h of insertion and at removal.Results:Both groups had similar median age,distribution in male to female ratio,and stone size.The overall median universal stent symptom questionnaire score at insertion was similar for bladder pain,flank or loin pain,and quality of life between Group 1 and 2;however,at removal Group 1 fared significantly better than Group 2,especially for flank or loin pain and pain at voiding.Both groups had similar ease in insertion with no hospital readmissions.Conclusion:Our audit favoured the single pigtail suture stent in Asian ureters in mitigating stent-related issues.It showed a good safety profile with easy deployment and removal.It promises a new standard in stenting.展开更多
BACKGROUND Tibial avulsion fractures of the posterior cruciate ligament(PCL)are challenging to treat and compromise knee stability and function.Traditional open surgery often requires extensive soft tissue dissection,...BACKGROUND Tibial avulsion fractures of the posterior cruciate ligament(PCL)are challenging to treat and compromise knee stability and function.Traditional open surgery often requires extensive soft tissue dissection,which may increase the risk of morbidity.In response to these concerns,arthroscopic techniques have been evolving.The aim of this study was to introduce a modified arthroscopic tech-nique utilizing an M-shaped suture fixation method for the treatment of tibial avulsion fractures of the PCL and to evaluate its outcomes through a case series.AIM To evaluate the effects of arthroscopic M-shaped suture fixation on treating tibia avulsion fractures of the PCL.METHODS We developed a modified arthroscopic M-shaped suture fixation technique for tibia avulsion fractures of the PCL.This case series included 18 patients who underwent the procedure between January 2021 and December 2022.The patients were assessed for range of motion(ROM),Lysholm score and International knee documentation committee(IKDC)score.Postoperative complications were also recorded.RESULTS The patients were followed for a mean of 13.83±2.33 months.All patients showed radiographic union.At the final follow-up,all patients had full ROM and a negative posterior drawer test.The mean Lysholm score significantly improved from 45.28±8.92 preoperatively to 91.83±4.18 at the final follow-up(P<0.001),and the mean IKDC score improved from 41.98±6.06 preoperatively to 90.89±5.32 at the final follow-up(P<0.001).CONCLUSION The modified arthroscopic M-shaped suture fixation technique is a reliable and effective treatment for tibia avulsion fractures of the PCL,with excellent fracture healing and functional recovery.展开更多
BACKGROUND Rotator cuff tears and Bankart lesions significantly affect shoulder function and quality of life.Arthroscopic rotator cuff repair and Bankart repair has become the standard treatment for restoring function...BACKGROUND Rotator cuff tears and Bankart lesions significantly affect shoulder function and quality of life.Arthroscopic rotator cuff repair and Bankart repair has become the standard treatment for restoring function and reducing pain.Recent advancements include new suture anchor technologies,such as the Sironix suture anchor known for its biomechanical strength and promising outcomes.However,there are limited real-world data on its effectiveness and safety,particularly in the Indian population.AIM To evaluate the effectiveness and safety of Sironix suture anchors in rotator cuff and Bankart repair surgeries.METHODS Sixty participants underwent surgery between January 2021 and December 2022,and demographic data and postoperative outcomes were collected through retrospective reviews and telephonic interviews.Validated scales,including the PENN Shoulder Score(PSS),Disabilities of the Arm,Shoulder,and Hand(DASH)score,and Single Assessment Numeric Evaluation(SANE),were utilized for assessment.RESULTS Treatment with Sironix suture anchor devices,including Ceptre Knotted UHMWPE Suture Titanium Anchor,Spyke Knotted UHMWPE Suture Peek Anchor,Stativ Knotted UHMWPE Suture Anchor,and Viplok Knotless Peek Screw Anchor with Titanium Tip,revealed no repair failures.Participants demonstrated high satisfaction and functional improvement,as evidenced by the mean Quick DASH score(32.01)and PSS(71.65)and the satisfactory SANE scores for both injured joints(74.33)and non-injured(83.67)shoulder joints.CONCLUSION The study yielded favorable outcomes for rotator cuff tear repair and Bankart repair.No repair failures were observed,supporting the safety and efficacy of these devices in shoulder injury management.展开更多
By analyzing teleseismic waveforms recorded by 53 stations of Hi-Climb profile passing through the central Bangong-Nujiang suture(BNS) ,a total of 4764 high-quality receiver functions are obtained.The average crustal ...By analyzing teleseismic waveforms recorded by 53 stations of Hi-Climb profile passing through the central Bangong-Nujiang suture(BNS) ,a total of 4764 high-quality receiver functions are obtained.The average crustal thickness and Poisson's ratio beneath each station are estimated using the travel time of Ps and PpPs of the Moho.The discontinuities such as the Moho,the 410and 660-km interfaces are also studied using the common converted points(CCP) time to depth migration of receiver functions. The main results are as follows:(1) The Moho of Lhasa terrane and that of Qiangtang terrane nearby BNS are overridden and offset by~10 km.The structural geometry shows a northward uplifting and the southward deepening for the Moho of Lhasa terrane and Qiangtang terrane,respectively,which is related to the reactivated structure beneath BNS since Cenozoic era.(2) The variation range of Poisson's ratios along the profile is between 0.237 and 0.280,indicating that the crust is mainly composed of felsic and intermediate rocks.The anti-correlation between the crustal thickness and Poisson's ratio suggests that thicker crust beneath the southern Qiangtang terrane may be related to the successive thrust of felsic and intermediate rock of Lhasa terrane.(3) The thickness of the mantle transition zone along the profile remains about 255 km,implying that the tectonic activities caused by the India-Asia collision are confined to the depths above 410 km.展开更多
The Dingqing ophiolite is located in the eastern segment of the Bangong-Nujiang suture zone. This suture zone is W–E trending parallel with the Yarlung–Zangbo suture zone and is an strategic area for exploring chrom...The Dingqing ophiolite is located in the eastern segment of the Bangong-Nujiang suture zone. This suture zone is W–E trending parallel with the Yarlung–Zangbo suture zone and is an strategic area for exploring chromite deposits in China. The Dingqign ophiolite is distributed in near SE-NW direction. According to the spatial distribution, the Dingqing ophiolite is sudivided into two massifs, including the East and the West massifs. The Dingqing ophiolite covers an area of nearly 600 km2. This ophiolite is composed of peridotite, pyroxenite, gabbro, diabase, basalt, plagiogranite and chert(Fig. 1). The peridotite is the main lithology of the Dingqing ophiolite. The peridotite covers about 90% of the total area of the Dingqing ophiolite. The Dingqing ophiolite is dominated by harzburgite with a small amounts of dunite. The Dingqing harzburgite displays different textures, such as massive, Taxitic, oriented and spherulitic textures(Fig. 2d–i). These four types of harzburgite occur in both the East and West massifs, especially in the Laraka area of the eastern part of the East massif. Dunites have different occurrences in the field outcrops, such as lenticular or stripshaped, thin-shell and agglomerate varieties(Fig. 2a–c). On the basis of detailed field work, we have discovered 83 chromitite bodies, including 27 in the East massif and 56 in the West massif. According to the occurrence scale and quantity of the chromitite bodies, we have identified four prospecting areas, namely Laraka, Latanguo, Langda and Nazona. Chromitites in the Dingqing ophiolite show different textures, including massive, disseminated, veined and disseminated-banded textures(Fig. 3). On the basis of the Cr#(=Cr/(Cr+Al)×100) of chromite, we have classified the Dingqing chromitite into high-Cr, medium high chromium type, medium chromium type and low chromium type chromitite(Figs. 4, 5). Among them, low chromium type chromitite Cr# is extremely low, ranging from 9.23 to 14.01, with an average of 11.89;TiO2 content is 0.00% to 0.04%, and the average value is 0.01%, which may be a new output type of chromitite. These different types of chromitites have different associations/assemblages of mineral inclusions. The inclusions in high chromium type chromitite are mainly clinopyroxene and a small amount of olivine;medium high chromium chromitite are mainly amphibole, a small amount of clinopyroxene and phlogopite;while low-chromium chromite rarely develops mineral inclusions, and micron-sized clinopyroxene inclusions are common in olivines which are gangue mineral in it. These different types of chromite ore bodies have a certain correspondence with the field output, and may also restrict their genesis. This part will be further developed in the follow-up work.展开更多
文摘The Beila ophiolite is located in the middle part of the Bangong-Nujiang suture zone,northern Tibetan plateau.It is a complete ophiolite suite,and plays a key role in understanding the evolution of the Bangong-Nujiang suture zone,as well as the Meso-Tethys Ocean.The Beila ophiolite was composed of peridotite,serpentinite,gabbro,pillow basalt,and minor rodingite.Peridotites comprisemainlymedium–tocoarse–grained serpentinized harzburgites and minor plagioclase-bearing lherzolites and dunites.There are some felsic-ultramafic dykes within the peridotite and they are mainlypegmatoidal pyroxenites,coarse to fine-grained gabbros,and diabases.Gabbros included isotropic and cumulate gabbros,and they commonly contain minor pegmatoidal gabbros veins.Pillow basalts and basaltic andesites overlaid on the margin of the serpentinized peridotites.Rodingite occurs as lenses and/or dykes within the host serpentinized peridotites.Zircon SHRIMP U–Pb dating for two rodingite samples yielded the ages ranging from172 to 164 Ma.Whole-rock geochemical and zircon Hf isotopic data show that the Beila ophiolite shows SSZ-type ophiolite affinity.Finally,we suggest that the Beila ophiolite was generated in an initial subduction process at the middle Jurassic(164–172 Ma).
文摘Yongzhu–Guomang Lake ophiolitic melange exposed about 100 km with large scale and complete ophiolitic uint in Xainza County,Xizang(Tibet).It is connected with Nam Lake,Kaimeng ophiolitic mélange to the east,and
文摘There is a long-term dispute at Moho depth across the Bangong-Nujiang suture (BNS). Due to the complicated and changeable seismic geological condition, it is not easy to acquire images of the reflective Moho in central Tibet. In the support of the SinoProbe project, a series of deep seismic reflection profiles were conducted to image Moho structure across the BNS and the Qiangtang terrane. These profiles extend from the northern Lhasa terrane to the Qiangtang terrane crossing the BNS. Both shot gathers and migration data show clear Moho images beneath the BNS. The Moho depth varies from 75.1 km (~24 s TWT) beneath the northmost Lhasa terrane to 68.9 km (~22 s TWT) beneath southmost Qiangtang terrane, and rises smoothly to 62.6 km (~20 s TWT ) at ~28 km north of the BNS beneath the Qiangtang terrane. We speculate that the Moho appears a 6.2 km sharp offset across the BNS and becomes ~12.5 km shallower from the northmost Lhasa terrane to the south Qiangtang terrane at ~28 km north of the BNS. The viewpoint of Moho depth across the BNS based on deep seismic reflection data is inconsistent with the previous 20 km offset.
基金DFG-Tibet-Projects SCHN 202/14-1 and attained with the assistance of the AvH.
文摘The ophiolite-bearing Bangong-Nujiang zone (BNZ) traversing central Tibet from east to west separates the Qiangtang block in the north from the Lhasa block in the south. The Cretaceous of the area includes Chuanba Formation (K 1c ), Duoba Formation (K 1d ), Langshan Formation (K 1l ) and Jiangba Formation (K 2j ). The K 1c is composed of black shale, sandy pelite, siltstone, sandstone, coal beds and volcanic rocks, of shallow marine facies. The K 1 d consists of terrestrial siliciclastics intercalated with some calcareous sandstone beds bearing Orbitolina sp. indicating marine influence. The K 1j is carbonate platform deposits of shallow marine and lagoon. The K 2j is characterized by terrestrial thick massive red conglomerate. An active margin related to B-subduction zone is considered to be the geological setting of the Cretaceous sedimentation.
基金This observational study was approved by the Ethics Committee of Renmin Hospital of Wuhan University.
文摘BACKGROUND Endoscopic full-thickness resection(EFTR)of gastric submucosal tumors(SMTs)is safe and effective;however,postoperative wound management is equally important.Literature on suturing following EFTR for large(≥3 cm)SMTs is scarce and limited.AIM To evaluate the efficacy and clinical value of double-nylon purse-string suture in closing postoperative wounds following EFTR of large(≥3 cm)SMTs.METHODS We retrospectively analyzed the data of 85 patients with gastric SMTs in the fundus of the stomach or in the lesser curvature of the gastric body whose wounds were treated with double-nylon purse-string sutures after successful tumor resection at the Endoscopy Center of Renmin Hospital of Wuhan University.The operative,postoperative,and follow-up conditions of the patients were evaluated.RESULTS All tumors were completely resected using EFTR.36(42.35%)patients had tumors located in the fundus of the stomach,and 49(57.65%)had tumors located in the body of the stomach.All patients underwent suturing with double-nylon sutures after EFTR without laparoscopic assistance or further surgical treatment.Postoperative fever and stomach pain were reported in 13(15.29%)and 14(16.47%)patients,respectively.No serious adverse events occurred during the intraoperative or postoperative periods.A postoperative review of all patients revealed no residual or recurrent lesions.CONCLUSION Double-nylon purse-string sutures can be used to successfully close wounds that cannot be completely closed with a single nylon suture,especially for large(≥3 cm)EFTR wounds in SMTs.
基金the National Natural Science Foundation of China(Grant Nos.91955206,41603038)Second Tibetan Plateau Scientific Expedition and Research program(Grant No.2019QZKK0803)+2 种基金Scientific Research Foundation for Advanced ScholarsWest Yunnan University of Applied Sciences(Grant No.2022RCKY0004)Yunnan Fundamental Research Projects(Grant No.202301AT070012).
文摘In this study,zircon U-Pb dating of volcanic rocks from the Zhongba ophiolite of the Yarlung Zangbo Suture Zone(YZSZ)in southern Xizang(Tibet)yielded an age of 247±3 Ma.According to whole rock geochemical and Sr-NdPb isotopic data,the Early Triassic samples could be divided into two groups:Group 1 with P-MORB affinity,showing initial^(87)Sr/^(86)Sr ratios of 0.70253–0.70602,ε_(Nd)(t)values of 4.2–5.3,(^(206)Pb/^(204)Pb)_(t)ratios of 16.353–18.222,(^(207)Pb/^(204)Pb)_(t)ratios of 15.454–15.564,and(^(208)Pb/^(204)Pb)_(t)ratios of 35.665–38.136;Group 2 with OIB affinity,showing initial^(87)Sr/^(86)Sr ratios of 0.70249–0.70513,ε_(Nd)(t)values of 4.4–4.9,(^(206)Pb/^(204)Pb)_(t)ratios of 17.140–18.328,(^(207)Pb/^(204)Pb)_(t)ratios of 15.491–15.575,and(^(208)Pb/^(204)Pb)_(t)ratios of 36.051–38.247.Group 2 rocks formed by partial melting of the mantle source enriched by a former plume,and assimilated continental crustal material during melt ascension.The formation of Group 1 rocks corresponds to the mixing of OIB melts,with the same components as Group 2 and N-MORBs.The Zhongba Early Triassic rocks belong to the continental margin type ophiolite and formed in the continental–oceanic transition zone during the initial opening of the Neo-Tethys in southern Xizang(Tibet).
基金supported by National Key Research and Development Program of China 2023YFC3605600(L.Y.)National Natural Science Foundation of China 82201045(F.Y.),82100982(F.L.)and 82202666(P.Y.)Young Elite Scientist Sponsorship Program by CAST(2022QNRC001 to F.Y.).
文摘Precise orchestration of cell fate determination underlies the success of scaffold-based skeletal regeneration.Despite extensive studies on mineralized parenchymal tissue rebuilding,regenerating and maintaining undifferentiated mesenchyme within calvarial bone remain very challenging with limited advances yet.Current knowledge has evidenced the indispensability of rebuilding suture mesenchymal stem cell niches to avoid severe brain or even systematic damage.But to date,the absence of promising therapeutic biomaterials/scaffolds remains.The reason lies in the shortage of fundamental knowledge and methodological evidence to understand the cellular fate regulations of scaffolds.To address these issues,in this study,we systematically investigated the cellular fate determinations and transcriptomic mechanisms by distinct types of commonly used calvarial scaffolds.Our data elucidated the natural processes without scaffold transplantation and demonstrated how different scaffolds altered in vivo cellular responses.A feasible scaffold,polylactic acid electrospinning membrane(PLA),was next identified to precisely control mesenchymal ingrowth and self-renewal to rebuild non-osteogenic suture-like tissue at the defect center,meanwhile supporting proper osteointegration with defect bony edges.Especially,transcriptome analysis and cellular mechanisms underlying the well-orchestrated cell fate determination of PLA were deciphered.This study for the first time cellularly decoded the fate regulations of scaffolds in suture-bony composite defect healing,offering clinicians potential choices for regenerating such complicated injuries.
基金Supported by Tianjin Health Research Project(No.TJWJ2022ZD009)Science and Technology Foundation of Tianjin Eye Hospital(No.YKPY2207)Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-016A).
文摘Dear Editor,We described an innovative“single self-leading suture technique”for repairing iridodialysis.Instead of moving the needle forth and back,our method is easier to manipulate in the narrow surgical space between the cornea and lens,which will decrease the unnecessary complications related to iatrogenic injury.We provide an economical friendly and less time-taking method,which improves the suture accuracy.
基金the Nature and Science of Science Technology Department of Fujian Province(No.2020J01233).
文摘AIM:To report a technique used with intermittent slidinglock-knot(ISLK)fixation for limbal conjunctival autografts in pterygium surgery and compared with those of routine intermittent(RI)fixation.METHODS:Consecutive patients with primary pterygium who had undergone pterygium excision combined with limbal conjunctival autograft transplantation between March 2021 and March 2022 at our institute were retrospectively analyzed.Primary outcome measures were mean duration of surgery and suture removal,degree of conjunctival hyperemia on postoperative day 1,pain score at suture removal,postoperative symptoms at 6mo,including conjunctival hyperemia,foreign body sensation,and graft stability.RESULTS:Ninety-eight patients underwent monocular surgery and were divided into ISLK(51 eyes)and RI(47 eyes)groups according to the type of conjunctiva autograft fixation method planned.There was no significant difference in mean duration of surgery between the two groups(18.59±2.39min vs 18.15±2.20min,P=0.417);however,compared to the RI group,shorter suture removal times were observed in the ISLK group[0.58min(0.42-0.87)vs 3.00min(2.21-4.15),P<0.001].The degree of conjunctival hyperemia on postoperative day 1 was milder in the ISLK group(P<0.001).Pain scores at suture removal were lower in the ISLK group than in RI group[1(0-3)vs 2(1-4),P<0.001].Postoperative symptoms at 6mo were comparable between the groups(P=0.487),with no recurrence.CONCLUSION:ISLK is an innovative method for limbal conjunctival autograft fixation after pterygium excision.Compared to RI fixation,ISLK facilitates suture removal and reduces discomfort,with comparable surgery duration and less conjunctival hyperemia.
文摘Objective:Double-J(DJ)ureteric stents are commonly placed perioperatively for semirigid or flexible ureteroscopic renal surgery.It is believed that lesser stent material within the bladder mitigates stent-related symptoms.This study aimed to evaluate the J-Fil ureteral stent,a single pigtail suture stent compared with conventional DJ stent in relation to stent symptoms in an Asian population undergoing ureterorenal intervention.Methods:Based on internal audit committee recommendation approval,the records of 50 patients retrieved,available data of 41 patients who were prospectively enrolled into two groups(Group 1[J-Fil stent group],n=21 and Group 2[DJ stent group],n=20)between August 2020 to January 2021,were analysed.Parameters compared were nature of procedure,stone location and size,ease of deployment or removal,and complications.A modified universal stent symptom questionnaire was used to assess morbidity of stent symptoms within 48 h of insertion and at removal.Results:Both groups had similar median age,distribution in male to female ratio,and stone size.The overall median universal stent symptom questionnaire score at insertion was similar for bladder pain,flank or loin pain,and quality of life between Group 1 and 2;however,at removal Group 1 fared significantly better than Group 2,especially for flank or loin pain and pain at voiding.Both groups had similar ease in insertion with no hospital readmissions.Conclusion:Our audit favoured the single pigtail suture stent in Asian ureters in mitigating stent-related issues.It showed a good safety profile with easy deployment and removal.It promises a new standard in stenting.
文摘BACKGROUND Tibial avulsion fractures of the posterior cruciate ligament(PCL)are challenging to treat and compromise knee stability and function.Traditional open surgery often requires extensive soft tissue dissection,which may increase the risk of morbidity.In response to these concerns,arthroscopic techniques have been evolving.The aim of this study was to introduce a modified arthroscopic tech-nique utilizing an M-shaped suture fixation method for the treatment of tibial avulsion fractures of the PCL and to evaluate its outcomes through a case series.AIM To evaluate the effects of arthroscopic M-shaped suture fixation on treating tibia avulsion fractures of the PCL.METHODS We developed a modified arthroscopic M-shaped suture fixation technique for tibia avulsion fractures of the PCL.This case series included 18 patients who underwent the procedure between January 2021 and December 2022.The patients were assessed for range of motion(ROM),Lysholm score and International knee documentation committee(IKDC)score.Postoperative complications were also recorded.RESULTS The patients were followed for a mean of 13.83±2.33 months.All patients showed radiographic union.At the final follow-up,all patients had full ROM and a negative posterior drawer test.The mean Lysholm score significantly improved from 45.28±8.92 preoperatively to 91.83±4.18 at the final follow-up(P<0.001),and the mean IKDC score improved from 41.98±6.06 preoperatively to 90.89±5.32 at the final follow-up(P<0.001).CONCLUSION The modified arthroscopic M-shaped suture fixation technique is a reliable and effective treatment for tibia avulsion fractures of the PCL,with excellent fracture healing and functional recovery.
文摘BACKGROUND Rotator cuff tears and Bankart lesions significantly affect shoulder function and quality of life.Arthroscopic rotator cuff repair and Bankart repair has become the standard treatment for restoring function and reducing pain.Recent advancements include new suture anchor technologies,such as the Sironix suture anchor known for its biomechanical strength and promising outcomes.However,there are limited real-world data on its effectiveness and safety,particularly in the Indian population.AIM To evaluate the effectiveness and safety of Sironix suture anchors in rotator cuff and Bankart repair surgeries.METHODS Sixty participants underwent surgery between January 2021 and December 2022,and demographic data and postoperative outcomes were collected through retrospective reviews and telephonic interviews.Validated scales,including the PENN Shoulder Score(PSS),Disabilities of the Arm,Shoulder,and Hand(DASH)score,and Single Assessment Numeric Evaluation(SANE),were utilized for assessment.RESULTS Treatment with Sironix suture anchor devices,including Ceptre Knotted UHMWPE Suture Titanium Anchor,Spyke Knotted UHMWPE Suture Peek Anchor,Stativ Knotted UHMWPE Suture Anchor,and Viplok Knotless Peek Screw Anchor with Titanium Tip,revealed no repair failures.Participants demonstrated high satisfaction and functional improvement,as evidenced by the mean Quick DASH score(32.01)and PSS(71.65)and the satisfactory SANE scores for both injured joints(74.33)and non-injured(83.67)shoulder joints.CONCLUSION The study yielded favorable outcomes for rotator cuff tear repair and Bankart repair.No repair failures were observed,supporting the safety and efficacy of these devices in shoulder injury management.
基金supported by the National Basic Research Program of China(Grant No.2008CB425704)
文摘By analyzing teleseismic waveforms recorded by 53 stations of Hi-Climb profile passing through the central Bangong-Nujiang suture(BNS) ,a total of 4764 high-quality receiver functions are obtained.The average crustal thickness and Poisson's ratio beneath each station are estimated using the travel time of Ps and PpPs of the Moho.The discontinuities such as the Moho,the 410and 660-km interfaces are also studied using the common converted points(CCP) time to depth migration of receiver functions. The main results are as follows:(1) The Moho of Lhasa terrane and that of Qiangtang terrane nearby BNS are overridden and offset by~10 km.The structural geometry shows a northward uplifting and the southward deepening for the Moho of Lhasa terrane and Qiangtang terrane,respectively,which is related to the reactivated structure beneath BNS since Cenozoic era.(2) The variation range of Poisson's ratios along the profile is between 0.237 and 0.280,indicating that the crust is mainly composed of felsic and intermediate rocks.The anti-correlation between the crustal thickness and Poisson's ratio suggests that thicker crust beneath the southern Qiangtang terrane may be related to the successive thrust of felsic and intermediate rock of Lhasa terrane.(3) The thickness of the mantle transition zone along the profile remains about 255 km,implying that the tectonic activities caused by the India-Asia collision are confined to the depths above 410 km.
基金granted by National Natural Science Foundation of China(Grant No.41720104009)China Geology Survey Project(Grant No.DD20160023-01)Foundation of MLR(Grant No.201511022)
文摘The Dingqing ophiolite is located in the eastern segment of the Bangong-Nujiang suture zone. This suture zone is W–E trending parallel with the Yarlung–Zangbo suture zone and is an strategic area for exploring chromite deposits in China. The Dingqign ophiolite is distributed in near SE-NW direction. According to the spatial distribution, the Dingqing ophiolite is sudivided into two massifs, including the East and the West massifs. The Dingqing ophiolite covers an area of nearly 600 km2. This ophiolite is composed of peridotite, pyroxenite, gabbro, diabase, basalt, plagiogranite and chert(Fig. 1). The peridotite is the main lithology of the Dingqing ophiolite. The peridotite covers about 90% of the total area of the Dingqing ophiolite. The Dingqing ophiolite is dominated by harzburgite with a small amounts of dunite. The Dingqing harzburgite displays different textures, such as massive, Taxitic, oriented and spherulitic textures(Fig. 2d–i). These four types of harzburgite occur in both the East and West massifs, especially in the Laraka area of the eastern part of the East massif. Dunites have different occurrences in the field outcrops, such as lenticular or stripshaped, thin-shell and agglomerate varieties(Fig. 2a–c). On the basis of detailed field work, we have discovered 83 chromitite bodies, including 27 in the East massif and 56 in the West massif. According to the occurrence scale and quantity of the chromitite bodies, we have identified four prospecting areas, namely Laraka, Latanguo, Langda and Nazona. Chromitites in the Dingqing ophiolite show different textures, including massive, disseminated, veined and disseminated-banded textures(Fig. 3). On the basis of the Cr#(=Cr/(Cr+Al)×100) of chromite, we have classified the Dingqing chromitite into high-Cr, medium high chromium type, medium chromium type and low chromium type chromitite(Figs. 4, 5). Among them, low chromium type chromitite Cr# is extremely low, ranging from 9.23 to 14.01, with an average of 11.89;TiO2 content is 0.00% to 0.04%, and the average value is 0.01%, which may be a new output type of chromitite. These different types of chromitites have different associations/assemblages of mineral inclusions. The inclusions in high chromium type chromitite are mainly clinopyroxene and a small amount of olivine;medium high chromium chromitite are mainly amphibole, a small amount of clinopyroxene and phlogopite;while low-chromium chromite rarely develops mineral inclusions, and micron-sized clinopyroxene inclusions are common in olivines which are gangue mineral in it. These different types of chromite ore bodies have a certain correspondence with the field output, and may also restrict their genesis. This part will be further developed in the follow-up work.