Two-dimensional time-resolved particle image velocimetry(TR-PIV)and stereographic particle image velocimetry(SPIV)techniques were used to investigate the effect of leading-edge tubercles on the flow over low-aspect-ra...Two-dimensional time-resolved particle image velocimetry(TR-PIV)and stereographic particle image velocimetry(SPIV)techniques were used to investigate the effect of leading-edge tubercles on the flow over low-aspect-ratio wing models.The angle of attack is fixed at 10°,and the Reynolds number based on chord length is 5.8×10^(3).It is shown that the leading-edge tubercles can effectively mitigate flow separation in the model and also reduce the contribution of wake vortex to the fluctuating energy of flow.Counter-rotating vortex pairs(CVPs)initiated from the peak of leading-edge tubercles can promote nearby momentum exchange,enhance mixing of the flow and increase the energy contained in the boundary layer,which results in resisting the larger adverse pressure gradient.Therefore,it is concluded that CVPs play an important role in mitigating the flow separation for wings with leading-edge tubercles.展开更多
BACKGROUND Tibial tubercle osteotomy(TTO) is a well-established surgical technique to deal with a stiff knee in revision total knee arthroplasty(RTKA). However, several reports have described potential osteotomy-relat...BACKGROUND Tibial tubercle osteotomy(TTO) is a well-established surgical technique to deal with a stiff knee in revision total knee arthroplasty(RTKA). However, several reports have described potential osteotomy-related complications such as nonunion, tibial tubercle migration and fragmentation, and metalware related pain.AIM To evaluate the literature and estimate the efficiency of TTO in RTKA in terms of osteotomy union, knee mobility and complications.METHODS MEDLINE, Scopus, and the Cochrane Central Register of Controlled Trials were investigated for completed studies until February 2020. The principle outcome of the study was the incidence of union of the osteotomy. Secondary outcomes were the knee range of motion as well as the TTO-related and overall procedure complication rate.RESULTS Fifteen clinical studies with a total of 593 TTOs were included. The TTO union rate was 98.1%. Proximal migration and anterior knee pain were the most common TTO-related complications accounting for 6.9% and 6.4% of all cases,respectively. However, only 2.2% of cases suffering from anterior knee pain needed hardware removal. Knee flexion was improved from 82.9° preoperatively to 100.1° postoperatively and total knee range of motion was increased from 73.4° before surgery to 97° after surgery. Stiffness requiring manipulation under anesthesia was recorded in 4.6% of cases. No major complications were reported.CONCLUSION The current systematic review supports the use of TTO in RTKA, as it is associated with high union rate, significant improvement in knee motion and low osteotomy-related complication risk that rarely leads to secondary tibial tubercle procedures.展开更多
BACKGROUND Several previous studies have reported an unusual root formation in which a fractured apical fragment of an immature root continued to develop independent of the main root after trauma to an immature tooth....BACKGROUND Several previous studies have reported an unusual root formation in which a fractured apical fragment of an immature root continued to develop independent of the main root after trauma to an immature tooth.To date,there have been only rare reports of the continuing apical formation of the fractured root associated with dens evaginatus(DE).This paper presents a case of a separated root tip formation associated with a fractured tubercle of DE.CASE SUMMARY An 11-year-old boy was referred for gingival sinus on the buccal side of the right mandibular second premolar(tooth#45).Clinically,tooth#45 was free of caries,but there was a sign of a fractured tubercle of DE on the occlusal surface.Radiography showed that the root canal of tooth#45 was widely radiolucent.A separated root apex was found apically under the main root and was nearly completely formed with an apical orifice at the apical tip.Tooth#45 was diagnosed as tubular fracture of DE with chronic apical periodontitis.A revascularization technique was recommended to treat the tooth.At 3-mo and 1-yr follow-up,the patient remained asymptomatic.Periapical radiography revealed that the separated root tip distally drifted with closure of the apex.However,the root length and thickness of the main root did not increased.CONCLUSION Clinicians should be aware that even if tubercle of DE is fractured in an immature tooth,the root tip may be separated from the main root and completely formed.展开更多
BACKGROUND Identification of the morphology of the genial tubercles (GTs) is valuable for different dental applications. The morphological pattern of the GTs is still controversial, and therefore, the study of its mor...BACKGROUND Identification of the morphology of the genial tubercles (GTs) is valuable for different dental applications. The morphological pattern of the GTs is still controversial, and therefore, the study of its morphology using cone beam computed tomography (CBCT) plays a valuable role in resolving the controversy. AIM To assess the morphological pattern, dimensions and position of the GTs using CBCT among a selected Saudi population. METHODS CBCT records of 155 Saudi subjects (49 female and 106 male) were used to assess the pattern and size of the GTs and to determine the distance from the apices of the lower central incisors to the superior border of the incisors (I-SGT) and the distance from the inferior border of the GTs to the menton (IGT-M). RESULTS The results of this study showed that the most common morphological pattern was of two superior GTs and a rough impression below them (36.8%), followed by two superior GTs and a median ridge representing fused inferior GTs below them (22.6%) and a single median eminence or projection (20%). The classically described pattern, of two superior and two inferior GTs placed one above the other, was found in only 14.2% of cases, while 6.4% of the studied cases had no GTs. The mean width and height were 6.23 ± 1.93 mm and 6.67 ± 3.04 mm, respectively, while the mean I-SGT and IGT-M measurements were 8.26 ± 2.7 mm and 8.13 ± 3.07 mm, respectively. CONCLUSION The GTs are a controversial anatomical landmark with wide variation in their morphological pattern. The most common pattern among the studied Saudi sample was of two superior GTs and a rough impression below them, and there were no significant differences between males and females.展开更多
To distinguish the taxonomy of Yihuang wild rice found in Yihuang County, Jiangxi Province, China in 1999, the botanical characteristics of Yihuang wild rice were retrieved by genus, and species; at the same time, the...To distinguish the taxonomy of Yihuang wild rice found in Yihuang County, Jiangxi Province, China in 1999, the botanical characteristics of Yihuang wild rice were retrieved by genus, and species; at the same time, the tubercle characters on lemma in Yihuang wild rice, O. rufipogon, 0. officinalis, 0. meyeriana, and O. granulata, were also observed by scanning electron microscopy. The retrieval result by genus showed that Yihuang wild rice is Leersia Soland. Ex Swartz., not Oryza L., Hygroryza Nees and Chikusichloa Koidz. The retrieval result by species showed that Yihuang wild rice is L. sayanuka Ohwi, not L. hexandra Swartz., L. japonica (Makino) Honda and L. oryzoides (L.) Swartz. The results of the SEM observation on tubercles on lemma showed that the tubercle characters on lemma of Yihuang wild rice belongs to "inlaid- silica-peak" type, which is different from the three types of wild rice existing in China, O. rufipogon, O. officinalis, O. Meyeriana, and also O. granulata, but is similar to L. tisseranti, thereby gives a proof of the above retrieval results. It could be concluded that Yihuang wild rice does not belong to Oryza L., but to Leersia sayanuka Ohwi of Leersia Soland. Ex Swartz.展开更多
Dear Editor,I am Bing Li from the Department of Ophthalmology,Peking Union Medical College Hospital in Beijing, China,and I write to present a case report of choroidal and ciliary body tubercles.Ocular tuberculosis (T...Dear Editor,I am Bing Li from the Department of Ophthalmology,Peking Union Medical College Hospital in Beijing, China,and I write to present a case report of choroidal and ciliary body tubercles.Ocular tuberculosis (TB) is an extrapulmonary tuberculous condition with variable manifestations[1].展开更多
目的探讨糖尿病合并跟骨结节撕脱性骨折患者实施切开复位空心螺钉结合锚钉固定术(open reduction and internal fixation,ORIF)的效果。方法回顾性研究2020年8月—2022年4月北京丰台医院收治的22例糖尿病合并跟骨结节撕脱性骨折的患者,...目的探讨糖尿病合并跟骨结节撕脱性骨折患者实施切开复位空心螺钉结合锚钉固定术(open reduction and internal fixation,ORIF)的效果。方法回顾性研究2020年8月—2022年4月北京丰台医院收治的22例糖尿病合并跟骨结节撕脱性骨折的患者,采用切开复位空心螺钉结合锚钉固定术治疗。围手术期及术后进行血糖的评估;术后随访使用足踝关节预后评分(foot and ankle outcome score,FAOS)、视觉模拟量表(visual analogue scale,VAS)、单脚跟抬高测试和X射线图像进行评估。结果所有骨折均在解剖位置愈合,没有出现术后固定失败、内固定松动移位以及皮肤感染、坏死等情况。术后随访6~8个月,所有患者都恢复了完全的足底屈曲范围和力量,没有步态异常或负重限制。FAOS评分:疼痛(80.85±6.20)分,症状(79.85±4.90)分,日常生活(72.35±8.00)分,运动和娱乐功能(68.25±11.93)分,足踝活动影响(77.47±6.70)分。VAS评分为(2.16±0.30)分。结论切开复位空心螺钉结合锚钉固定术是治疗糖尿病相关跟骨结节撕脱性骨折的有效手段,并显示出良好的功能和影像学结果。展开更多
BACKGROUND De-Quervain’s tenosynovitis is a disorder arising from the compression and irritation of the first dorsal extensor compartment of the wrist.Patients who fail conservative treatment modalities are candidate...BACKGROUND De-Quervain’s tenosynovitis is a disorder arising from the compression and irritation of the first dorsal extensor compartment of the wrist.Patients who fail conservative treatment modalities are candidates for surgical release.However,risks with surgery include damage to the superficial radial nerve and an incomplete release due to inadequate dissection.Currently,there is a paucity of literature demonstrating the exact anatomic location of the first dorsal extensor compartment in reference to surface anatomy.Thus,this cadaveric study was performed to determine the exact location of the first extensor compartment and to devise a reliable surgical incision to prevent complications.AIM To describe the location of the first dorsal compartment in relation to bony surface landmarks to create replicable surgical incisions.METHODS Six cadaveric forearms,including four left and two right forearm specimens were dissected.Dissections were performed by a single fellowship trained upper extremity orthopaedic surgeon.Distance of the first dorsal compartment from landmarks such as Lister’s tubercle,the wrist crease,and the radial styloid were calculated.Other variables studied included the presence of the superficial radial nerve overlying the first dorsal compartment,additional compartment subsheaths,number of abductor pollicis longus(APL)tendon slips,and the presence of a pseudo-retinaculum.RESULTS Distance from the radial most aspect of the wrist crease to the extensor retinaculum was 5.14 mm±0.80 mm.The distance from Lister’s tubercle to the distal aspect of the extensor retinaculum was 13.37 mm±2.94 mm.Lister’s tubercle to the start of the first dorsal compartment was 18.43 mm±2.01 mm.The radial styloid to the initial aspect of the extensor retinaculum measured 2.98 mm±0.99 mm.The retinaculum length longitudinally on average was 26.82 mm±3.34 mm.Four cadaveric forearms had separate extensor pollicis brevis compartments.The average number of APL tendon slips was three.A pseudo-retinaculum was present in four cadavers.Two cadavers had a superficial radial nerve that crossed over the first dorsal compartment and retinaculum proximally(7.03 mm and 13.36 mm).CONCLUSION An incision that measures 3 mm proximal from the radial styloid,2 cm radial from Lister’s tubercle,and 5 mm proximal from the radial wrist crease will safely place surgeons at the first dorsal compartment.展开更多
目的探讨联合超微血流成像(superb microvascular imaging,SMI)和彩色多普勒血流显像(color Doppler flow imaging,CDFI)在乳腺影像学报告和数据系统(breast imaging reporting and data system,BI-RADS)分级为4类的微小结节诊断中的应...目的探讨联合超微血流成像(superb microvascular imaging,SMI)和彩色多普勒血流显像(color Doppler flow imaging,CDFI)在乳腺影像学报告和数据系统(breast imaging reporting and data system,BI-RADS)分级为4类的微小结节诊断中的应用,并与超声造影(contrast-enhanced ultrasound,CEUS)结果比较。方法前瞻性纳入乳腺BI-RADS分级4类、最大径≤1 cm,并经术后病理检查证实的165例乳腺微小结节患者共165例病灶,其中良性病灶125例、恶性病灶40例,每例病灶均进行CDFI、SMI及CEUS检查,分析其声像图资料。采用Adler半定量法进行血流分级评价,比较CDFI和SMI显示微小结节内血流情况的差异。制定了CDFI、CDFI+SMI联合两种方式预测结节性质的诊断标准,分析了CDFI、CDFI和SMI联合及CEUS三种血流显像方法对乳腺微小结节性质的诊断价值。结果恶性乳腺微小结节患者患病年龄大于良性患者,CDFI及SMI对乳腺微小结节血流检出能力不同,CDFI血流显示率为47.3%(78/165)、SMI为83.6%(138/165)。以病理结果为金标准,CDFI、联合CDFI和SMI、CEUS三种方法诊断乳腺微小结节的灵敏度分别为72.5%、87.5%、72.5%,特异度分别为60.8%、59.2%、82.4%,准确性分别为63.6%、66.1%、80.0%,曲线下面积(area under the curve,AUC)分别为0.665、0.771、0.772,且三种方式对微小结节诊断的差异有统计学意义,表明联合应用CDFI和SMI的方式优于单独使用CDFI。结论对于诊断为BI-RADS 4类的乳腺微小结节,联合应用CDFI和SMI,可有助于提高判断结节性质的灵敏度,并减少有创性检查超声造影的使用。展开更多
Introduction: Tuberculosis is a chronic infectious disease that remains a global public health problem. Children, accounting for 10% of cases, are particularly vulnerable to this disease. Based on a case of multifocal...Introduction: Tuberculosis is a chronic infectious disease that remains a global public health problem. Children, accounting for 10% of cases, are particularly vulnerable to this disease. Based on a case of multifocal tuberculosis in a 14-month-old infant, the authors conducted a literature review on this condition. Observation: The case involved a 14-month-old infant referred from a health center for persistent symptoms including anemia, fever, and lateral deviation of the mouth during crying. Clinical examination revealed an infectious and meningeal syndrome, as well as facial paralysis. The results of brain imaging, cerebrospinal fluid examination, fundus examination, and gastric lavage fluid examination led to the conclusion of multifocal tuberculosis in the infant without association with HIV. Improvement was observed one week after the start of antituberculosis treatment, with complete recovery without sequelae after 12 months. Conclusion: Although rare, multifocal tuberculosis does exists and its diagnosis remains challenging in infants. Early treatment generally leads to favorable outcomes, especially in the absence of HIV coinfection.展开更多
The influences of leading-edge tubercle amplitude on airfoil flow field have been analyzed at high angle of attack.The accuracy of a large eddy simulation(LES)research is validated through quantitative comparisons wit...The influences of leading-edge tubercle amplitude on airfoil flow field have been analyzed at high angle of attack.The accuracy of a large eddy simulation(LES)research is validated through quantitative comparisons with corresponding experimental results.Then,a proper orthogonal decomposition(POD)analysis has been carried out based on the unsteady flow field and the fluid mechanisms of corresponding POD modes have been identified.Consequently,the influences of leading-edge tubercle amplitude have been uncovered.Since the streamwise vorticity is larger than that of small amplitude cases,the momentum transfer process at peaks is more obvious for large amplitude,leading to delayed flow separation.Both amplitude and wavelength play important roles in the generation of laminar separation bubble(LSB)at troughs.Moreover,the Karman vortex shedding process takes place at specific trough sections as pairs of periodic spatial structures exist in the dominant POD modes.The destruction of Karman vortex shedding process is strengthened along with the increase of amplitude.展开更多
基金financial support from the National Natural Science Foundation of China under grand No.11721202。
文摘Two-dimensional time-resolved particle image velocimetry(TR-PIV)and stereographic particle image velocimetry(SPIV)techniques were used to investigate the effect of leading-edge tubercles on the flow over low-aspect-ratio wing models.The angle of attack is fixed at 10°,and the Reynolds number based on chord length is 5.8×10^(3).It is shown that the leading-edge tubercles can effectively mitigate flow separation in the model and also reduce the contribution of wake vortex to the fluctuating energy of flow.Counter-rotating vortex pairs(CVPs)initiated from the peak of leading-edge tubercles can promote nearby momentum exchange,enhance mixing of the flow and increase the energy contained in the boundary layer,which results in resisting the larger adverse pressure gradient.Therefore,it is concluded that CVPs play an important role in mitigating the flow separation for wings with leading-edge tubercles.
文摘BACKGROUND Tibial tubercle osteotomy(TTO) is a well-established surgical technique to deal with a stiff knee in revision total knee arthroplasty(RTKA). However, several reports have described potential osteotomy-related complications such as nonunion, tibial tubercle migration and fragmentation, and metalware related pain.AIM To evaluate the literature and estimate the efficiency of TTO in RTKA in terms of osteotomy union, knee mobility and complications.METHODS MEDLINE, Scopus, and the Cochrane Central Register of Controlled Trials were investigated for completed studies until February 2020. The principle outcome of the study was the incidence of union of the osteotomy. Secondary outcomes were the knee range of motion as well as the TTO-related and overall procedure complication rate.RESULTS Fifteen clinical studies with a total of 593 TTOs were included. The TTO union rate was 98.1%. Proximal migration and anterior knee pain were the most common TTO-related complications accounting for 6.9% and 6.4% of all cases,respectively. However, only 2.2% of cases suffering from anterior knee pain needed hardware removal. Knee flexion was improved from 82.9° preoperatively to 100.1° postoperatively and total knee range of motion was increased from 73.4° before surgery to 97° after surgery. Stiffness requiring manipulation under anesthesia was recorded in 4.6% of cases. No major complications were reported.CONCLUSION The current systematic review supports the use of TTO in RTKA, as it is associated with high union rate, significant improvement in knee motion and low osteotomy-related complication risk that rarely leads to secondary tibial tubercle procedures.
基金National Natural Science Foundation of China,No.81801028Natural Science Foundation of Zhejiang Province,No.LQ19H140001.
文摘BACKGROUND Several previous studies have reported an unusual root formation in which a fractured apical fragment of an immature root continued to develop independent of the main root after trauma to an immature tooth.To date,there have been only rare reports of the continuing apical formation of the fractured root associated with dens evaginatus(DE).This paper presents a case of a separated root tip formation associated with a fractured tubercle of DE.CASE SUMMARY An 11-year-old boy was referred for gingival sinus on the buccal side of the right mandibular second premolar(tooth#45).Clinically,tooth#45 was free of caries,but there was a sign of a fractured tubercle of DE on the occlusal surface.Radiography showed that the root canal of tooth#45 was widely radiolucent.A separated root apex was found apically under the main root and was nearly completely formed with an apical orifice at the apical tip.Tooth#45 was diagnosed as tubular fracture of DE with chronic apical periodontitis.A revascularization technique was recommended to treat the tooth.At 3-mo and 1-yr follow-up,the patient remained asymptomatic.Periapical radiography revealed that the separated root tip distally drifted with closure of the apex.However,the root length and thickness of the main root did not increased.CONCLUSION Clinicians should be aware that even if tubercle of DE is fractured in an immature tooth,the root tip may be separated from the main root and completely formed.
文摘BACKGROUND Identification of the morphology of the genial tubercles (GTs) is valuable for different dental applications. The morphological pattern of the GTs is still controversial, and therefore, the study of its morphology using cone beam computed tomography (CBCT) plays a valuable role in resolving the controversy. AIM To assess the morphological pattern, dimensions and position of the GTs using CBCT among a selected Saudi population. METHODS CBCT records of 155 Saudi subjects (49 female and 106 male) were used to assess the pattern and size of the GTs and to determine the distance from the apices of the lower central incisors to the superior border of the incisors (I-SGT) and the distance from the inferior border of the GTs to the menton (IGT-M). RESULTS The results of this study showed that the most common morphological pattern was of two superior GTs and a rough impression below them (36.8%), followed by two superior GTs and a median ridge representing fused inferior GTs below them (22.6%) and a single median eminence or projection (20%). The classically described pattern, of two superior and two inferior GTs placed one above the other, was found in only 14.2% of cases, while 6.4% of the studied cases had no GTs. The mean width and height were 6.23 ± 1.93 mm and 6.67 ± 3.04 mm, respectively, while the mean I-SGT and IGT-M measurements were 8.26 ± 2.7 mm and 8.13 ± 3.07 mm, respectively. CONCLUSION The GTs are a controversial anatomical landmark with wide variation in their morphological pattern. The most common pattern among the studied Saudi sample was of two superior GTs and a rough impression below them, and there were no significant differences between males and females.
基金supported by the National Natural Science Foundation of China(30560073)the Key Technologies R&D Program of Jiangxi Province,China(200210100210).
文摘To distinguish the taxonomy of Yihuang wild rice found in Yihuang County, Jiangxi Province, China in 1999, the botanical characteristics of Yihuang wild rice were retrieved by genus, and species; at the same time, the tubercle characters on lemma in Yihuang wild rice, O. rufipogon, 0. officinalis, 0. meyeriana, and O. granulata, were also observed by scanning electron microscopy. The retrieval result by genus showed that Yihuang wild rice is Leersia Soland. Ex Swartz., not Oryza L., Hygroryza Nees and Chikusichloa Koidz. The retrieval result by species showed that Yihuang wild rice is L. sayanuka Ohwi, not L. hexandra Swartz., L. japonica (Makino) Honda and L. oryzoides (L.) Swartz. The results of the SEM observation on tubercles on lemma showed that the tubercle characters on lemma of Yihuang wild rice belongs to "inlaid- silica-peak" type, which is different from the three types of wild rice existing in China, O. rufipogon, O. officinalis, O. Meyeriana, and also O. granulata, but is similar to L. tisseranti, thereby gives a proof of the above retrieval results. It could be concluded that Yihuang wild rice does not belong to Oryza L., but to Leersia sayanuka Ohwi of Leersia Soland. Ex Swartz.
文摘Dear Editor,I am Bing Li from the Department of Ophthalmology,Peking Union Medical College Hospital in Beijing, China,and I write to present a case report of choroidal and ciliary body tubercles.Ocular tuberculosis (TB) is an extrapulmonary tuberculous condition with variable manifestations[1].
文摘BACKGROUND De-Quervain’s tenosynovitis is a disorder arising from the compression and irritation of the first dorsal extensor compartment of the wrist.Patients who fail conservative treatment modalities are candidates for surgical release.However,risks with surgery include damage to the superficial radial nerve and an incomplete release due to inadequate dissection.Currently,there is a paucity of literature demonstrating the exact anatomic location of the first dorsal extensor compartment in reference to surface anatomy.Thus,this cadaveric study was performed to determine the exact location of the first extensor compartment and to devise a reliable surgical incision to prevent complications.AIM To describe the location of the first dorsal compartment in relation to bony surface landmarks to create replicable surgical incisions.METHODS Six cadaveric forearms,including four left and two right forearm specimens were dissected.Dissections were performed by a single fellowship trained upper extremity orthopaedic surgeon.Distance of the first dorsal compartment from landmarks such as Lister’s tubercle,the wrist crease,and the radial styloid were calculated.Other variables studied included the presence of the superficial radial nerve overlying the first dorsal compartment,additional compartment subsheaths,number of abductor pollicis longus(APL)tendon slips,and the presence of a pseudo-retinaculum.RESULTS Distance from the radial most aspect of the wrist crease to the extensor retinaculum was 5.14 mm±0.80 mm.The distance from Lister’s tubercle to the distal aspect of the extensor retinaculum was 13.37 mm±2.94 mm.Lister’s tubercle to the start of the first dorsal compartment was 18.43 mm±2.01 mm.The radial styloid to the initial aspect of the extensor retinaculum measured 2.98 mm±0.99 mm.The retinaculum length longitudinally on average was 26.82 mm±3.34 mm.Four cadaveric forearms had separate extensor pollicis brevis compartments.The average number of APL tendon slips was three.A pseudo-retinaculum was present in four cadavers.Two cadavers had a superficial radial nerve that crossed over the first dorsal compartment and retinaculum proximally(7.03 mm and 13.36 mm).CONCLUSION An incision that measures 3 mm proximal from the radial styloid,2 cm radial from Lister’s tubercle,and 5 mm proximal from the radial wrist crease will safely place surgeons at the first dorsal compartment.
文摘目的探讨联合超微血流成像(superb microvascular imaging,SMI)和彩色多普勒血流显像(color Doppler flow imaging,CDFI)在乳腺影像学报告和数据系统(breast imaging reporting and data system,BI-RADS)分级为4类的微小结节诊断中的应用,并与超声造影(contrast-enhanced ultrasound,CEUS)结果比较。方法前瞻性纳入乳腺BI-RADS分级4类、最大径≤1 cm,并经术后病理检查证实的165例乳腺微小结节患者共165例病灶,其中良性病灶125例、恶性病灶40例,每例病灶均进行CDFI、SMI及CEUS检查,分析其声像图资料。采用Adler半定量法进行血流分级评价,比较CDFI和SMI显示微小结节内血流情况的差异。制定了CDFI、CDFI+SMI联合两种方式预测结节性质的诊断标准,分析了CDFI、CDFI和SMI联合及CEUS三种血流显像方法对乳腺微小结节性质的诊断价值。结果恶性乳腺微小结节患者患病年龄大于良性患者,CDFI及SMI对乳腺微小结节血流检出能力不同,CDFI血流显示率为47.3%(78/165)、SMI为83.6%(138/165)。以病理结果为金标准,CDFI、联合CDFI和SMI、CEUS三种方法诊断乳腺微小结节的灵敏度分别为72.5%、87.5%、72.5%,特异度分别为60.8%、59.2%、82.4%,准确性分别为63.6%、66.1%、80.0%,曲线下面积(area under the curve,AUC)分别为0.665、0.771、0.772,且三种方式对微小结节诊断的差异有统计学意义,表明联合应用CDFI和SMI的方式优于单独使用CDFI。结论对于诊断为BI-RADS 4类的乳腺微小结节,联合应用CDFI和SMI,可有助于提高判断结节性质的灵敏度,并减少有创性检查超声造影的使用。
文摘Introduction: Tuberculosis is a chronic infectious disease that remains a global public health problem. Children, accounting for 10% of cases, are particularly vulnerable to this disease. Based on a case of multifocal tuberculosis in a 14-month-old infant, the authors conducted a literature review on this condition. Observation: The case involved a 14-month-old infant referred from a health center for persistent symptoms including anemia, fever, and lateral deviation of the mouth during crying. Clinical examination revealed an infectious and meningeal syndrome, as well as facial paralysis. The results of brain imaging, cerebrospinal fluid examination, fundus examination, and gastric lavage fluid examination led to the conclusion of multifocal tuberculosis in the infant without association with HIV. Improvement was observed one week after the start of antituberculosis treatment, with complete recovery without sequelae after 12 months. Conclusion: Although rare, multifocal tuberculosis does exists and its diagnosis remains challenging in infants. Early treatment generally leads to favorable outcomes, especially in the absence of HIV coinfection.
基金This work was supported by the National Key R&D Program of China(Grant No.2022YFB2402801)the National Natural Science Foundation of China(Grant No.11972250 and 11672206)+1 种基金the Key Program of Tianjin Natural Science Foundation(Grant No.19JCZDJC32000)the Tianjin Natural Science Foundation(Grant No.20JCQNJC01950).
文摘The influences of leading-edge tubercle amplitude on airfoil flow field have been analyzed at high angle of attack.The accuracy of a large eddy simulation(LES)research is validated through quantitative comparisons with corresponding experimental results.Then,a proper orthogonal decomposition(POD)analysis has been carried out based on the unsteady flow field and the fluid mechanisms of corresponding POD modes have been identified.Consequently,the influences of leading-edge tubercle amplitude have been uncovered.Since the streamwise vorticity is larger than that of small amplitude cases,the momentum transfer process at peaks is more obvious for large amplitude,leading to delayed flow separation.Both amplitude and wavelength play important roles in the generation of laminar separation bubble(LSB)at troughs.Moreover,the Karman vortex shedding process takes place at specific trough sections as pairs of periodic spatial structures exist in the dominant POD modes.The destruction of Karman vortex shedding process is strengthened along with the increase of amplitude.