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Roles of Eph/ephrin bidirectional signaling during injury and recovery of the central nervous system 被引量:4
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作者 Yue Wan Jin-Shan Yang +3 位作者 Li-Cai Xu Xiao-Jiang Huang Wei Wang Min-Jie Xie 《Neural Regeneration Research》 SCIE CAS CSCD 2018年第8期1313-1321,共9页
Multiple cellular components, including neuronal, glial and endothelial ceils, are involved in the sophis- ticated pathological processes following central nervous system injury. The pathological process cannot reduce... Multiple cellular components, including neuronal, glial and endothelial ceils, are involved in the sophis- ticated pathological processes following central nervous system injury. The pathological process cannot reduce damage or improve functional recovery by merely targeting the molecular mechanisms of neuronal cell death after central nerve system injuries. Eph receptors and ephrin ligands have drawn wide attention since the discovery of their extensive distribution and unique bidirectional signaling between astrocytes and neurons. The roles of Eph/ephrin bidirectional signaling in the developmental processes have been re- ported in previous research. Recent observations suggest that Eph/ephrin bidirectional signaling continues to be expressed in most regions and cell types in the adult central nervous system, playing diverse roles. The Eph/ephrin complex mediates neurogenesis and angiogenesis, promotes glial scar formation, regulates endocrine levels, inhibits myelin formation and aggravates inflammation and nerve pain caused by injury. ~lhe interaction between Eph and ephrin is also considered to be the key to angiogenesis. This review focus- es on the roles of Eph/ephrin bidirectional signaling in the repair of central nervous system injuries. 展开更多
关键词 nerve regeneration Eph/ephrin bidirectional signaling central nervous system INJURY RECOVERY NEURONS glial cells
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20.231 Gbit/s tricolor red/green/blue laser diode based bidirectional signal remodulation visible-light communication system 被引量:6
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作者 LIANG-YU WEI CHIN-WEI HSU +1 位作者 CHI-WAI CHOW CHIEN-HUNG YEH 《Photonics Research》 SCIE EI 2018年第5期422-426,共5页
We propose and experimentally demonstrate a recorded 1-m bidirectional 20.231-Gbit/s tricolor R/G/B laser diode(LD) based visible-light communication(VLC) system supporting signal remodulation. In the signal remodulat... We propose and experimentally demonstrate a recorded 1-m bidirectional 20.231-Gbit/s tricolor R/G/B laser diode(LD) based visible-light communication(VLC) system supporting signal remodulation. In the signal remodulation system, an LD source is not needed at the client side. The client reuses the downstream signal sent from the central office(CO) and remodulates it to produce the upstream signal. As the LD sources are located at the CO, the laser wavelength and temperature managements at the cost-sensitive client side are not needed.This is the first demonstration, to our knowledge, of a >20 Gbit∕s data rate tricolor R/G/B VLC signal transmission supporting upstream remodulation. 展开更多
关键词 bidirectional signal remodulation visible-light communication system blue laser
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