Visual performance after implantation of two types of phakic foldable intraocular lenses for correction of high myopia

AIM: To compare Visian lens(model V4 c) and Artiflex lens regarding quality(contrast sensitivity) and quantity(efficacy, predictability, safety and stability) of vision in correcting high myopia with recording and analysis of complications. METHODS: The comparative prospective study included 39 eyes of 23 patients with high myopia, 19 eyes had Visian lens implantation(model V4 c) and 20 eyes had Artiflex lens implantation. The inclusion criteria were high myopia(higher than 6.0 D) and stable refraction(<0.5 D change over one year). Outcomes included assessment of safety and efficacy indices, predictability, stability, contrast sensitivity and analysis of complications at postoperative 1 d, 1 wk and 1, 3, 6 and 12 mo. Selection of the type of phakic intraocular lens for patients was based on surgeons' preferences, which was no specific selection criteria. RESULTS: After 12 mo of follow up, difference in uncorrected and corrected distant visual acuity(CDVA) between both groups was statistically insignificant(UDVA for VisianV4 c and Artiflex lens were 0.33±0.2 logMAR and 0.37±0.2 logMAR respectively, P=0.59, CDVA for VisianV4 c and Artiflex lens were 0.155±0.1 logMAR and 0.147± 0.1 logMAR respectively, P=0.87). The efficacy index was 1.25 for VisianV4 c lens and 0.8 for Artiflex lens, 78.9% of eyes were within one diopter spherical equivalent in Visian V4 c lens group compared to 70% in the Artiflex lens group. No eye lost lines of CVDA proving a good safety index for both lenses(safety index was 1.67 for VisianV4 c lens and 1.34 for Artiflex lens). Difference in contrast sensitivity between both groups was statistically insignificant(P=0.15, 0.88, 0.27, 0.32 and 0.82 at five spatial frequencies). CONCLUSION: Both Visian ICL V4 c and Artiflex lensesare safe and effective with stable and predictable refraction and they have comparable contrast sensitivity outcomes with no vision threatening complications.

Evaluation of suturless scleral fixation with posterior chamber foldable intraocular lens implantation

AIM: To assess the sutureless scleral fixation technique for posterior chamber foldable intraocular lens(PCIOL) implantation in aphakic eyes with insufficient or no capsular support. METHODS: A technique for sutureless intrascleral fixation of the haptics of a standard 3-piece PCIOL was used which ensures sutureless fixation by permanent incarceration of the haptics in a scleral tunnel parallel to the limbus. All patients were evaluated for preoperative status [visual acuity, refractive error, K readings, intraocular pressure(IOP) measurement, slit lamp examination, fundus examination and optical biometry], postoperative status and complications. Ultrasound biomicroscopy(UBM) was done for 10 cases to evaluate optic tilt. RESULTS: The study evaluated 42 eyes of 42 patients. The follow-up period was 6 mo. Improvement of best corrected visual acuity(BCVA) one line occurred in 10 cases(23.8%) and loss of one line in 3 cases(7.1%). Intraoperative complications included: haptic kink in 4 cases(9.5%), haptic breakage in 1 case(2.4%), haptic dislocation in 1 case(2.4%), haptic slippage in 3 cases(7.1%), IOL dislocation in 1 case(2.4%) and sclerotomy related bleeding in 1 case(2.4%). Postoperative complications included: transient mild vitreous hemorrhage in 3 cases(7.1%), choroidal detachment in 1 case(2.4%), cystoid macular edema(CME) in 1 case(2.4%), optic capture in 1 case(2.4%), subconjunctival haptic in 2 cases(4.8%), ocular hypotony in 4 cases(9.5%) and ocular hypertension in 1 case(2.4%). There were no cases of retinal detachment or endophthalmitis. UBM showed optic tilt in 3 cases(30%). CONCLUSION: Fixation of three-piece foldable IOL haptics in scleral tunnel parallel to the limbus-providedaxial stability and proper centration of the IOL with minimal or no tilt in most cases and a low complication rate during the follow up period which lasted 6 mo.

Comparison of Trans-scleral Fixation of PMMA and Foldable Intraocular Lens in Children

Purpose: To observe the difference of the effects of PMMA and foldable intraocular lenses (IOLs) trans-sclerally fixed in pediatric eyes. Methods: Thirty-two children (43 eyes) who had undergone trans-scleral fixation of IOL were retrospected, of whom 5 children were implanted PMMA IOL in both eyes, 6children were implanted PMMA IOL in one eye and foldable IOL in the other eye, 12children were implanted foldable IOL in one eye and 9 chilrden were implanted PMMA IOL in one eye. Mean age was 5.3 years ( range 2.5 ～ 12 years ). Twelve children had traumatic cataract and the others congenital cataract before lens extraction. Results: Foldable group (18 eyes ): Mean follow-up was 12.1 months. Visual acuity (VA): compared with the best corrected VA before IOL fixation, postoperative best corrected VA improved in 16 eyes, remained unchanged in 2 eyes. In 14 eyes, one or two stitches were needed to seal the incision. Complications: Severe anterior chamber reaction was seen in 3 eyes. Intraocular bleeding was found in 3 eyes. IOL decentration was detected in 1 eye. Iris capture of IOL was seen in one eye. PMMA group (25 eyes ):Mean follow-up was 20.3 months. Visual acuity (VA): compared with the best corrected VA before IOL fixation, postoperative best corrected VA improved in 19 eyes,remained unchanged in 5 eyes and got worse in one eye. In 24 eyes, one to three stitches were needed to seal the incision. Complications: Severe anterior chamber reaction was seen in 5 eyes. Intraocular bleeding was found in 4 eyes. IOL decentration was seen in one eye. Iris capture of IOL was seen in 3 eyes. Intraocular pressure elevated in one eye. Conclusion: Our study shows that trans-scleral fixation of IOL is a safe procedure in pediatric eyes. Foldable IOL showed similar effect compared with PMMA IOL in pediatric trans-scleral fixation. Eye Science 2001; 17:61 ～ 64.

Application of Foldable Intraocular Lens in Multiple Types of Cataract

Objective: To evaluate the clinical results of implantation of foldable intraocular lens inmultiple types of cataract.Methods: This retrospective study comprised 162 eyes of 148 patients undergoingphacoemulsification and implantation of foldable intraocular lens, some of whom under-went combined pars plana vitrectomy or trabeculectomy or silicone oil removal. Theperiod of follow-up was from 3 months to 17 months.Results: There is slight reaction postoperatively in all cases. The postoperative uncorrectedvisual acuites was from 0. 05 to 1.2, patient with 0.6 or above acuity were 70.98%. Aneodymium: YAG capsulotomy was required in 5 eyes. Posterior capsule ruptured in 1eyes, and a PMMA intraocular lens was implanted in ciliary sulcus. In one eye, a lenswas removed because of recurrence of retina detachment.Conclusions: The application of foldable intraocular lens in multiple types of cataract issafe, and there is a slight postoperative reaction. less complications , and fast visualacuity recovery.

Comparison of iris-fixated foldable lens and scleralfixated foldable lens implantation in eyes with insufficient capsular support

AIM： To compare the outcomes of vision using two different intraocular lens（IOL） replacement techniques,iris-fixated foldable intraocular lens（IF-IOL） and scleralfixated foldable intraocular lens（SF-IOL） in patients with insufficient capsular support.METHODS： Total 63 eyes（62 patients） with insufficient posterior capsule support underwent replacement of IF-IOL or SF-IOL between January 2008 and August 2011.Outcome measures included changes in visual acuity, slit lamp examination, refractive indices and corneal curvatures. RESULTS： The mean improvement of uncorrected visual acuity（UCVA） was greater in IF-IOL group compared to the SF-IOL group（0.43 D±0.19 D vs 0.35 D±0.18 D, P 〈0.05）. Moreover, 12（38.71%） eyes in IF-IOL group and 4（12.50%） in SF-IOL group had a higher postoperative UCVA than preoperative best corrected visual acuity（BCVA） while 9（29.03%） eyes in IF-IOLgroup and 18（56.25%） in SF-IOL group had a lower postoperative UCVA than preoperative BCVA. The myopic mean manifest sphere and mean cylinder magnitude were lower in the IF-IOL group than that in the SF-IOL group（-0.47 D±0.58 D vs 0.50 D±0.43 D, P 〈0.01; 0.84 D ±0.53 D vs 1.23 D ±0.70 D, P 〈0.05）. No difference of corneal astigmatism and surgically induced astigmatism was found between the two groups. In addition, fewer complications were observed in IF-IOL eyes. CONCLUSION： IF-IOL implantation can give a significant improvement in vision with fewer complications than SF-IOL in patients with insufficient capsular support.

Foldable Lens Explantation and Exchange: The Reason and Solution

Objective: To report the explantation and exchange of Hydrophilic Acrylic foldable intraocular lens (IOL) on 14 patients who had visual disturbances caused by the change of transparence on optic. Methods: Sixteen Hydrophilic Acrylic foldable intraocular lenses from 14 patients who presented with decreased visual acuity from 6 months to 1 year after normal phacoemulsification and IOL implantation associated with extensive transparent change on optic of the lens. The lenses were explanted with the bisection technique. All the eyes were reinserted with Acrysof foldable lenses. Results: Sixteen lenses were removed successfully and exchanged with the new lens in the capsule. The posterior capsular rupture and vitreous loss were found in the first two cases. One of them had the zonulysis due to the radial tear of the anterior capsule during the enlargement of the capsular opening. The anterior vitrectomy was performed with IOL fixed on the ciliary sulcus. The visual acuity of all the patients improved obviously without posterior complication. Conclusion: Foldable lens explantation with the bisection technique and exchange had a successful outcome with improvement of ocular condition. Eye science 2001; 17:54 ～56.

AcrySof phakic angle-supported intraocular lens for the correction of high to extremely high myopia:one-year follow-up results

AIM: To assess the safety, efficacy and predictability of the AcrySof phakic angle-supported intraocular lens (IOL) (Alcon Inc., U.S.A.) for correction of high-to-extremely high myopia in adults. METHODS: In this prospective study performed in Tianjin Medical University Eye Center & College of Optometry, Tianjin, China, 25 eyes of 13 patients were implanted with AcrySof phakic angle-supported IOLs and followed for 1 year postoperatively. Preoperative manifest refractive sphere was (-12.08 +/- 2.44) diopters (D) and cylinder was (-1.35 +/- 0.62)D. Visual acuity, predictability and stability of manifest refraction spherical equivalent (MRSE), adverse events, and endothelial cell density were analyzed during 1-year of follow-up. RESULTS: After 1 year of follow-up, no eyes lost 1 line (best spectacle-corrected visual acuity)BSCVA; an uncorrected visual acuity (UCVA) of 20/20 or better was achieved in 60% of eyes; 100% had an UCVA of 20/40 or better; a BSCVA of 20/30 or better was achieved by 100% of eyes; 84% had a BSCVA of 20/20 or better. The overall mean percentage change in endothelial cell density 1 year after surgery was (-0.27 +/- 3.60)%. Two eyes (8%) had increased intraocular pressure (IOP) on the day of surgery. No pupil ovalization, pupillary block, or retinal detachment events were observed. CONCLUSION: After 1 year of follow-up, the implantation of AcrySof phakic angle-supported IOL is proved to be safe, effective and predictable with minimal complications in patients with high-to-extremely high myopia. Due to the limitation of visiting time, long-term of clinical investigation is necessary to verify the safety and efficacy of this IOL.

Corneal injection track: an unusual complication of intraocular lens implantation and review

Phacoemulsification is the main gold standard for cataract operation in the developed world together with foldable intraocular lens(IOL) implantation by injection,allowing for stable wound construction and less postoperative astigmatism. It is a safe procedure with high success rate with the advancement in machines,improvement of IOL injection systems and further maturation of surgeons’ techniques. Despite the large number of operations performed every day, foldable IOL injection leading to an intra-stromal corneal track is a very rare complication. We report a case of this unusual finding in a 70-year-old gentleman who has undergone cataract operation in November 2011 in our hospital and will review on the complications related to foldable IOL injection.

白内障撕囊口控制环的临床应用价值分析

目的 评价白内障撕囊口控制环的临床应用效果。方法 选取60例(60眼)年龄相关性白内障患者为研究对象,按照随机数字表法分为A组与B组,每组30例(30眼)。A组行常规连续环形撕囊白内障超声乳化+折叠式人工晶状体植入术, B组在白内障撕囊口控制环辅助下行连续环形撕囊白内障超声乳化+折叠式人工晶状体植入术。比较两组撕囊口合格率、人工晶状体轻度偏移情况、视力、眼压,以及术中和术后并发症发生情况。结果 两组均顺利完成连续环形撕囊。A组撕囊口合格24眼(80.0%), B组合格30眼(100.0%)。B组撕囊口合格率高于A组,差异有统计学意义(P<0.05)。两组术后1个月人工晶状体轻度偏移率比较差异无统计学意义(P>0.05)。两组术后1 d、1周视力>0.5占比比较,差异无统计学意义(P>0.05)。术前, A组眼压为(14.17±2.47)mm Hg(1 mm Hg=0.133 kPa), B组为(14.60±2.97)mm Hg;术后A组眼压为(15.37±3.59)mm Hg, B组为(15.63±3.05)mm Hg。手术前后两组眼压比较差异无统计学意义(P>0.05)。术中两组无一例发生前房出血、虹膜损伤及后囊膜破裂。术后两组无一例发生前房渗出,两组角膜水肿及前房闪辉发生率比较差异无统计学意义(P>0.05)。两组角膜水肿均在1周内消退。结论 白内障撕囊口控制环可明显提高撕囊口合格率,有助于手术顺利完成,使人工晶状体处于完美位置,并提高手术的安全性。

人工晶状体巩膜缝线固定术矫正儿童玻璃体切割术后无晶状体眼疗效分析

目的评价二期人工晶状体巩膜缝线固定术矫正儿童玻璃体切割术后无晶状体眼的疗效。方法对16例16眼儿童玻璃体切割术后(其中8例因化脓性眼内炎、8例因外伤性视网膜脱离行手术)的无晶状体眼行四襻折叠人工晶状体经巩膜缝线固定术;术中全程均使用前房维持器。患者平均年龄为(7.62±2.02)岁(5～11岁),术前最佳矫正视力平均为0.25±0.24,患儿平均眼压为(13.14±0.33)mmHg(1kPa=7.5mmHg),其中10眼有角膜瘢痕。术后随访6～22个月,平均(12.56±5.73)个月。结果术后早期原发病为眼内炎者有5眼出现低眼压,平均为(6.02±1.34)mmHg,一般在术后7d恢复正常眼压。末次随访时,尚未出现缝线暴露、人工晶状体脱位与偏斜和视网膜脱离等严重并发症;患眼最佳矫正视力平均为0.29±0.21,其中最佳矫正视力<0.05者2眼,0.05～0.3者5眼,≥0.3者9眼。结论儿童玻璃体切割术后二期人工晶状体行经巩膜缝线固定术,是矫正儿童单侧无晶状体眼的较好方法,但如何预防和处理患者术后早期低眼压以及对其远期疗效和并发症的评价仍需长期随访观察。

超声乳化联合折叠人工晶状体推注式植入治疗超高度近视白内障疗效观察

目的观察晶状体超声乳化吸出联合推注式折叠人工晶状体(IOL)植入术治疗白内障合并超高度近视的临床效果。方法对81例(98只眼)白内障患者合并超高度近视行小切口超声乳化吸除联合推注式折叠IOL植入术。观察术后视力、角膜散光、并发症等情况。结果术后第一天裸眼视力≥0.2共76眼(77.56%),≥0.5共37只眼(37.76%);术后1月裸眼视力≥0.2共85只眼,占86.73%,≥0.5共42只眼,占42.86%。最佳矫正视力≥0.2共90只眼,占91.84%,最佳矫正视力≥0.5共72只眼,占73.50%。随访中5眼(5.10%)晶状体后囊膜混浊,无后囊破裂,视网膜、脉络膜脱离者。结论超声乳化联合推注式折叠IOL植入是治疗白内障合并超高度近视眼安全、有效的方法。

小切口两点固定折叠人工晶状体悬吊术的临床观察

目的:探讨小切口对无后囊膜无晶状体眼行两点固定折叠人工晶状体缝线悬吊术的临床疗效。方法:对11例11眼无后囊膜或后囊膜不足以支撑人工晶状体的患者用RAYNER(570C)折叠式人工晶状体,通过小切口两点固定行折叠人工晶状体悬吊术,观察患者术后视力、并发症情况。结果:术后1d裸眼视力>0.5者5眼(46%),0.3～0.5者4眼(36%),2眼(18%)为0.2。术后1,3,6mo视力均达到或好于术前最佳矫正视力。无明显并发症发生。结论:小切口两点固定折叠人工晶状体悬吊术是治疗无囊膜无晶状体眼的一种安全有效的方法。

小切口非超声乳化联合推注式折叠型人工晶状体植入术

目的研究小切口非超声乳化联合推注式折叠型人工晶状体植入术治疗白内障的疗效.方法对34例38眼不同类型的白内障施行3 mm巩膜隧道切口非超声乳化白内障摘出联合推注式折叠型人工晶状体植入术.结果 38眼全部囊袋内植入人工晶状体,术后1 d视力≥0.8者12眼,0.4～0.6者22眼,视力≤0.3者4眼,术后2周视力≥0.8者15眼,0.4～0.6者21眼,视力≤0.3者2眼.术前、术后角膜散光差异无显著性(P>0.05).结论小切口非超声乳化联合推注式折叠型人工晶状体植入术实现了真正意义上的小切口手术,具有许多优点,是治疗白内障的一种好方法.

2.6mm切口人工晶状体植入治疗白内障合并高度近视的疗效观察

目的:观察使用MonarchⅡ折叠推注系统.通过2.6 mm角膜切口植入低度数或负度数丙烯酸脂(ActySof)折叠式人工晶状体治疗白内障合并高度近视的临床疗效。方法:对52例(68眼)白内障合并高度近视患者行超声乳化白内障吸除,使用MonarchⅡ折叠推注系统通过2.6 mm角膜切口植入低度数或负度数AcrySof折叠式人工晶状体,观察术中和术后并发症、术后视力。术后随访时间平均6个月(3～12个月)。结果:所有人工晶状体均能顺利植入眼内,没有发生人工晶状体断裂、擦痕、断襻或襻变形等情况,术中无并发症发生。术后3个月最佳矫正视力0.12—0.25者8眼(11.8％),0.3～0.5者21眼(30.9％),0.6～1.0者36眼(52.9％),大于1.0者3眼(4.4％);随访期间出现黄斑囊样水肿2眼,无出现视网膜脱离和后发性白内障者。结论:在白内障合并高度近视超声乳化吸除、低度数或负度数折叠式人工晶状体植入手术中,应用MonarchⅡ折叠推注系统可以将通常需要3.5 mm左右的切口减少为2.6 mm,是一种安全有效的方法。

微小切口推注式人工晶状体睫状沟悬吊术临床应用

目的:探讨微小切口推注式折叠人工晶状体睫状沟悬吊术的有效性和安全性。方法:选择因晶状体后囊破裂或悬韧带断裂不能正常植入后房型人工晶状体的患者52例52眼,利用推注器系统,通过3.2mm的透明角膜小切口,把襻预扎了聚丙烯缝线的折叠人工晶状体植入后房并缝合固定于睫状沟,观察术后视力、角膜散光度及并发症。结果:所有患者术后裸眼视力均提高,其中1.0以上8眼,0.6～0.8为18眼,0.4～0.6为16眼,0.4以下10眼。术后1wk;1,3mo视力在0.5以上者分别为33眼(63%)、39眼(75%)、41眼(79%)。术前及术后1wk;1,3mo的平均角膜散光度分别为1.86±1.65D,2.09±1.28D,1.92±1.34D和1.77±1.16D,术后各时期与术前的角膜散光度差别均无统计学意义(P>0.05)。术中、术后没有出现严重并发症。结论:微小切口推注式折叠人工晶状体睫状沟悬吊术为治疗晶状体、玻璃体切除术后,无晶状体囊支持的患者,提供了一个更安全可靠的人工晶状体植入方法。

白内障超声乳化术后囊膜混浊的多因素分析

目的研究白内障超声乳化术后发生后囊膜混浊的相关因素。方法采用多元逐步回归方法对可能引起后囊膜混浊的诸多因素进行分析。结果在105例经过6～18个月临床随访的患者中,发现与后囊膜混浊的相关因素是术后第1天前房反应及人工晶状体类型,其它因素包括病人性别、年龄、白内障类型、核硬度、眼轴长度、术中超声时间等均与后羹膜混浊无关。结论减轻术后第1天前房反应及选用丙烯酸酯类折叠式人工晶状体有助于减少后发障的发生率。

透明角膜小切口折叠人工晶体植入术

目的评价透明角膜小切口折叠人工晶体植入术的效果。方法经３．５ｍｍ小切口完成４１例４５眼。分别观察视力、角膜地形图及角膜内皮细胞丢失率。结果术后ｄ１，裸眼视力≥０．５占８２．３５％，≥１．０占５０％；术后１个月时≥０．５占１００％，≥１．０占７５．３２％。角膜地形图显示角膜切口附近较为平坦，但术后１月时可恢复至术前状态。角膜内皮丢失率术后１周为９．３７％±４．１２。结论透明角膜小切口折叠人工晶体植入术反应轻，散光小，视力恢复快。

可调节折叠人工晶状体临床应用初步报告

目的:通过植入一种新型的可调节折叠人工晶状体1CU,观察患者术后远近视力,观察改型人工晶状体的拟调节力。方法:对10眼单纯老年性白内障患者实施超声乳化联合囊袋内可调节折叠人工晶状体植入术,同期随机抽取10眼单纯老年性白内障行超声乳化及单焦点折叠晶状体植入术作为对照,于术前、及术后1wk;1,3mo查裸眼远近视力、矫正视力,并进行主客观验光。结果:1CU组裸眼近视力优于对照组(0.01<P<0.02),裸眼远视力及矫正远近视力无显著差异(P>0.2),两组手术前后散光无显著差异(P>0.05)。结论:植入可调节折叠人工晶状体后,术眼具有一定的假晶状体调节。

小切口Akreos Adapt AO折叠人工晶状体睫状沟固定术的方法改进

目的：探讨2.4mm小切口改良Akreos Adapt AO折叠人工晶状体经巩膜睫状沟固定术的的疗效。方法：选择由外伤、先天、手术等原因造成晶状体后囊破损或悬韧带离断不能正常植入后房型人工晶状体的患者37例37眼,制作角膜缘垂直的“钱包样冶板层巩膜瓣,采用博士伦Akreos Adapt AO折叠人工晶状体,利用瑞士产VE2200人工晶状体植入系统,经过透明角膜缘内2.4mm小切口,由双针各带有环形10/0的聚丙烯缝线将人工晶状体固定于睫状沟,埋藏式结扎缝线于板层巩膜瓣内。结果：所有患者术后植入的人工晶状体居中,裸眼视力均有不同程度的提高。术后3mo视力逸0.8者3眼（8%）;〉0.4-臆0.6者18眼（49%）;臆0.4者16眼（43%）。术前、术后3mo平均角膜散光分别为1.73±1.22、1.62±1.34D,差异无统计学意义（P〉0.05）。术中、术后除1例出现玻璃体积血,2例角膜水肿外,未见其它严重并发症。所有患者均无固定线结暴露。结论：2.4mm微创小切口行Akreos Adapt AO折叠人工晶状体睫状沟固定术,手术切口小、晶状体悬吊稳固、居中性好、视力恢复满意、术后角膜散光变化小。固定线结扎方法具有线结埋藏无暴露并同时关闭巩膜瓣切口的特点,操作步骤简捷、手术并发症少、实用有效可行。

后极性白内障超声乳化吸除及折叠型人工晶状体植入术的临床观察

目的:探讨小切口超声乳化治疗后极性白内障的手术技术以及术中、术后并发症的处理方法。方法:46例患者(61只眼),年龄38～78岁,平均57岁。在表麻下行颞侧透明角膜隧道切口的超声乳化,并对后囊下混浊斑块行剥离吸除、环形撕后囊或剪除混浊的后囊及折叠型人工晶状体植入术。结果:51只眼后囊膜完整,其中6只眼有后囊膜混浊;在10只后囊膜破裂眼中,4只眼有玻璃体脱出需行前段玻璃体切割术,并有1只眼晶状体皮质软壳沉入玻璃体腔引起葡萄膜炎及继发性青光眼需再次行后段玻璃体切割。58只眼人工晶状体囊袋内固定,3只眼睫状沟固定。结论:对后极性白内障行超声乳化手术时,谨慎处理后囊下混浊斑块,可以减少术中、术后的并发症,明显提高患者的术后视力。眼科学报2003;