Objective To synthesize18F labeled N-(2-18F-fluoropropionyl)-L-glutamine(18F-FPGLN)for tumor PET imaging,and to perform its biodistribution study on normal mice and PC-3 tumorbearing nude mice.Methods4-nitrophenyl-2-1...Objective To synthesize18F labeled N-(2-18F-fluoropropionyl)-L-glutamine(18F-FPGLN)for tumor PET imaging,and to perform its biodistribution study on normal mice and PC-3 tumorbearing nude mice.Methods4-nitrophenyl-2-18F-fluropropionate(18F-NFP)was synthesized on the MF-2V-IT-I synthesizer and was展开更多
文摘Objective To synthesize18F labeled N-(2-18F-fluoropropionyl)-L-glutamine(18F-FPGLN)for tumor PET imaging,and to perform its biodistribution study on normal mice and PC-3 tumorbearing nude mice.Methods4-nitrophenyl-2-18F-fluropropionate(18F-NFP)was synthesized on the MF-2V-IT-I synthesizer and was