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The Clinical Possibility to Make Use of P++ Strategy to Obtain Refined Biological Optimization for the Treatment of Locally Advanced Nasopharyngeal Carcinoma
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作者 FU Yu-chuan AI Ping +1 位作者 YANG Yu-qiong LI Ping 《Chinese Journal of Biomedical Engineering(English Edition)》 2012年第3期117-122,共6页
It has been believed that the better optimization can be achieved by tile P++ optimization strategy since the P+ curve shows a rather shallow maximum. In this paper, the P++ optimization strategy has been verifie... It has been believed that the better optimization can be achieved by tile P++ optimization strategy since the P+ curve shows a rather shallow maximum. In this paper, the P++ optimization strategy has been verified by evaluating (intensity-modulated radiation therapy, IMRT) plans for a T4 stage NPC patient in the situation where diffieuh compromise has to be made between probabilities for tumor control and normal tissue injuh'y. The results showed that including the biological objective gEUD into the plan optimization couht decrease the mean dose of OAR. Theoretically, P++ optimization strategy could be helpfnl to find the refined optimization solution for radiation therapy planning. However, in clinical radiotherapy practice, disease situations will form restrictions to use the biological evaluation only. More factors including both physical and biological models should be considered in a planning evaluation process to aehieve a best clinical solution. 展开更多
关键词 radiotherapy IMRT biological optimization P++ strategy plan evaluation
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Design and experiment on atomizer parameter of impinging low-speed centrifugal atomization sprayer
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作者 Dejiang Liu Yan Gong +2 位作者 Xiao Chen Xiao Zhang Guo Wang 《International Journal of Agricultural and Biological Engineering》 SCIE EI CAS 2020年第6期118-124,共7页
Atomizers were designed with different atomization parameters to obtain droplets that satisfy optimal particle size requirements for an impinging-type low-speed centrifugal atomizing sprayer.The main factors affecting... Atomizers were designed with different atomization parameters to obtain droplets that satisfy optimal particle size requirements for an impinging-type low-speed centrifugal atomizing sprayer.The main factors affecting droplet size are turntable speed,the number of teeth and the tooth shape of the toothed disc.Winner318 software was used to evaluate droplet sizes for different structures and the working parameters of the atomizer.The response surface method and Design-Expert were used to analyze the effect of each factor.The response surface analysis of the effect of structural and working parameters of the atomizer on the interaction between the volume medium diameter of the droplet and the spectral width of the droplet size was used to establish the atomizer droplet Granular spectrum prediction model.Optimal design fitting formulas are obtained,and the droplet sizes required for pesticides to control flying insect pests,to control the growth of reptile larvae,and the use of spraying fungicides to prevent crop damage were determined.This research provides a product not only similar to those in the market,but also the theoretical basis and references for innovation,development,and optimization of centrifugal atomization technology. 展开更多
关键词 centrifugal atomization impinging low-speed droplets diameter optimal biological particle size theory quadratic regression analysis
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