Improvement of the efficacy of influenza vaccination (H5N1) in chicken by using extract of Cochinchina momordica seed (ECMS)

Seeds of a Chinese traditional medicine plant, Cochinchina momordica were used in the present study for the improvement of influenza vaccine (H5N1) in chicken. Crude extraction from Cochinchina momordica seed (ECMS) was obtained by ethanol extraction method. In experiment No. 1, two weeks old chickens were immunized with influenza vaccine (H5N1) alone or combined with ECMS (5, 10, 20, 40 and 80 μg/dose). Serum IgG antibody levels (by ELISA) as well as effects on daily weight gain were measured on 0, 7, 14 and 28th day after immunization. Results revealed that all ECMS groups numerically increased the antibody levels while 10 and 20 μg/dose groups significantly (P<0.05) enhanced total IgG antibody on day 28, when compared with control. Average daily weight gain was also significantly higher in 20 μg/dose ECMS group. Adjuvant effect was also confirmed in experiment No. 2 when chickens were immunized with 20 μg/dose ECMS and antibody titer was measured through hemagglutination inhibition (HI). It is concluded that ECMS has potential to improve the immune responses and deserve further study as an adjuvant.

珠海市农村禽类养殖人员禽流感健康教育干预效果评价

目的了解珠海市农村禽类养殖人员预防人禽流感知识、态度和行为,评价健康教育干预措施的效果,为探索可行的干预策略提供依据。方法对珠海市农村地区的禽类养殖人员进行健康教育干预,干预前后分别采用多阶段分层随机整群抽样方法,抽取禽类养殖人员进行问卷调查,对干预效果进行评价。结果调查对象对禽流感相关知识和正确态度干预后较干预前均有显著改善(P<0.01);村民圈养家禽、正确洗手和病死禽的正确处理干预后较干预前均有显著提高(P<0.01),干预前后,村民获得禽流感知识的最主要途径都是电视。结论在农村地区开展形式多样的健康教育干预,能有效提高农村禽类养殖人员禽流感知识的知晓率,对于提高其健康意识和形成良好的行为习惯具有积极促进作用。

综合医院收治人感染H7N9禽流感后的防控工作

本文以综合医院为例,阐述医院收治人感染H7N9禽流感应该采取的防控措施,为我国医院开展人感染H7N9禽流感的防控提供参考。人感染H7N9禽流感对人类健康具有较大危害,对于其防控工作应该做到医院各部门、科室分工明确,各司其职;医教部院感科制定出人感染H7N9禽流感的防控细则,对医护人员进行培训,与应急办、护理部联合开展防控技术演练,实施防控技术知识竞赛,并对医护人员进行考核。本院从2014年至今收治了6例H7N9禽流感感染患者,确保了疾病没有出现扩大传播。