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Contrast enhancement of vascular walls of intracranial high flow malformations in black blood MRI indicates high inflammatory activity 被引量:1
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作者 Athanasios K.Petridis Maxine Dibue-Adjei +7 位作者 Jan F.Cornelius Marian Preetham Suresh Lan Li Marcel A.Kamp Yousef Abusabha Bernd Turowski Hans Jakob Steiger Rebecca May 《Chinese Neurosurgical Journal》 CSCD 2018年第2期89-93,共5页
Background: There are controversies concerning the natural history of arteriovenous malformations (AVMs) in literature and it is not clear which AVMs should be treated and which should be just observed. Objective crit... Background: There are controversies concerning the natural history of arteriovenous malformations (AVMs) in literature and it is not clear which AVMs should be treated and which should be just observed. Objective criteria beyond growth in serial MRIs or angiographies are needed. The use of black blood MRI is currently under investigation for evaluating the rupture risk of cerebral aneurysms, however its use for assessment of AVMs has yet to be evaluated. We therefore conducted a feasibility study on the application of black blood MRI (bbMRI) in AVMs to assess rupture risk. Methods: Retrospective study of 10 patients with intracranial AVMs and 4 patients with arteriovenous fistulas who received a black blood MRI before treatment. Results: AVM niduses (9/10) show contrast enhancement irrespective of rupture or size. All arteriovenous fistulas (4/4) were contrast enhancing irrespective of rupture. Conclusion: High flow malformations are in a permanent stage of inflammation which does not seem to allow conclusions on their rupture risk at the current stage. BbMRI is a feasible method of identifying inflammation in AVMs and arteriovenous fistulas. However, future prospective studies are needed to evaluate whether bbMRI contrast enhancement correlates with rupture risk. 展开更多
关键词 ARTERIOVENOUS MALFORMATION ARTERIOVENOUS FISTULA black blood MRI Inflammation
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Cavernous brain malformations and their relation to black blood MRI in respect to vessel wall contrast enhancement
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作者 Athanasios K.Petridis Marian P.Suresh +7 位作者 Jan F.Cornelius Richard Bostelmann Maxine Dibué-Adjei Lan Li Marcel A.Kamp Hans Jakob Steiger Bernd Turowski Rebecca May 《Chinese Neurosurgical Journal》 CSCD 2018年第2期65-68,共4页
Background: Inflammatory responses are implicated as crucial patho-mechanisms of vascular brain malformations. Inflammation is suggested to be a key contributor to aneurysm rupture; however it is unclear whether infla... Background: Inflammatory responses are implicated as crucial patho-mechanisms of vascular brain malformations. Inflammation is suggested to be a key contributor to aneurysm rupture; however it is unclear whether inflammation contributes similarly to bleeding of cerebral cavernous malformations (CCMs). Black blood MRI is a sequence which identifies inflammation in blood vessel walls and in the present study is used to detect inflammatory response in CCMs. Methods: Fifteen patients with 17 CCMs treated in our department in 2017 were retrospectively analysed. All patients received black blood MRIs and the results were analysed in correlation with, size and bleeding of CCMs. Results: Size and bleeding status of CCMs did not correlate with contrast enhancement in the CCM wall. One of 3 patients with bleeding displayed contrast enhancement in black blood MRI, whereas the others had non enhancing lesions. Because of the small number of cases a statistical analysis was not performed. Conclusion: In this limited cohort, inflammatory reactions in CCMs could not be detected by black blood MRI suggesting that the level of inflammation is minimal in these lesions and those different patho-mechanisms play a more important role in the rupture of CCMs. 展开更多
关键词 CAVERNOUS MALFORMATIONS Inflammation black blood MRI
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Determination of Blood Indices of Guide Black-Fur Sheep in Qinghai Province of China
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作者 ZOU Wen-hui SHEN Lei 《Animal Husbandry and Feed Science》 CAS 2009年第11期13-15,共3页
[ Objective] The research was aimed to provide the basis for the development and utilization of Guide black-fur sheep and its disease di- agnosis and prevention. [ Methed] Blood samples were collected from 15 healthy ... [ Objective] The research was aimed to provide the basis for the development and utilization of Guide black-fur sheep and its disease di- agnosis and prevention. [ Methed] Blood samples were collected from 15 healthy adult Guide black-fur sheep in Black-Fur Sheep Farm o'f Guinan County in Qinghai Province. Eighteen blood indices belonging to three classes, erythrocyte, leukocyte and platelet, were determined. E Resultl The blood indices of the Guide black-fur sheep were as follows: the white blood cell count, (7.52 ±2.72) × 109/L; the red blood cell count, (13.04 ± 2.81 ) × 1012/L; the mean corpuscular hemoglobin, (85.36 +27.05) g/L; the mean corpuscular volume, (37.22 ± 1.93) fL; the mean corpuscular hemoglobin concentration, (13.19 ±0.96) pg; the platelet count, (370.67 ± 139.60) × 109/L; the lymphocyte absolute count, (14.11 +9.36) x 109/L; the absolute count of intermediate cell, (0.79 ±0.46)× 109/L; and the absolute neutrophil count, (0.81 +0.71 ) ×109/L.- Conclusion] The reseamh lays the foundation for further Drotectina the aenetic resources of the Guide black-fur sheep and imDrovinQ their production performance. 展开更多
关键词 Guide black-fur sheep blood indices DETERMINATION
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Blood Typing of Asiatic Black Bear (Ursus thibetanus)
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作者 Li Qin Chen Yucun +3 位作者 Zhao Fengyong Zhang Jiamin Zhang Shuhui Zhu Ziyan 《Animal Husbandry and Feed Science》 CAS 2017年第5期322-325,共4页
[Objective]The paper was to analyze whether Asiatic black bear( Ursus thibetanus) had different blood group systems. [Method]Whole blood samples were collected from 40 Asiatic black bears in Fujian Province,China. Tub... [Objective]The paper was to analyze whether Asiatic black bear( Ursus thibetanus) had different blood group systems. [Method]Whole blood samples were collected from 40 Asiatic black bears in Fujian Province,China. Tube method was used to detect antibodies in plasma,and antibody isotype was determined with 2-mercaptoethanol. Plasma was further analyzed by mass spectrometry. [Result] The plasma from four black bears had antibodies,possibly Ig M isoform,which could agglutinate RBCs from 30 bears. Blood samples from 10 bears were tested by human blood typing reagents. The results showed that four black bears had blood type like human type O,while six bears had like human type B. Mass spectrometry results demonstrated that plasma protein had extensive homology to serum albumin-like isoform 1 found in giant panda( Ailuropoda melanoleuca). [Conclusion]Asiatic black bear might have at least one blood group system with two blood types. If the sick bear needs blood transfusion,a cross-matching test is necessary. Moreover,giant panda might receive blood from Asiatic black bear in case of emergency. 展开更多
关键词 Asiatic black BEAR (Ursus thibetanus) blood group system Cross matching test TRANSFUSION MEDICINE
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Analyzing of "Xu Sanguan a blood":The Black Humor Artistic
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作者 隋瑞歆 《海外英语》 2011年第4X期199-200,共2页
"Black Humor",as a literary genre."Xu Sanguan a Blood" is a novel created by a well-known writer Yu Hua in 1995.It expresses the human desire to survive when the bad luck.The story tells us that Xu... "Black Humor",as a literary genre."Xu Sanguan a Blood" is a novel created by a well-known writer Yu Hua in 1995.It expresses the human desire to survive when the bad luck.The story tells us that Xu Sanguan spent relying on selling blood they had to get a life and overcome adversity.And when he was old,Xu Sanguan knows that nobody should want his blood,his spirit has collapsed.Black humor from this man gives us more heavy consider and let's know what the truth of the life is.Xu Sanguan had the both of many hates and also many hopes about the family and the life in this story.And his black humor makes him crying with the smile and smiling with the tears. 展开更多
关键词 black HUMOR Xu Sanguan a blood ANALYZING
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Relationship between Obesity, Serum Uric Acid, Serum Potassium and Glomerular Filtration Rate with Electric Left Ventricular Hypertrophy in Blacks Central Africans with High Blood Pressure 被引量:1
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作者 Bertrand Fikahem Ellenga Mbolla Paul Macaire Ossou Nguiet +6 位作者 Richard Loumingou Meo Stéphane Ikama Narcisse Ngangoue Thierry Raoul Gombet Henri Germain Monabeka Benjamn Longo Mbenza Gisèle Kimbally Kaky 《World Journal of Cardiovascular Diseases》 2018年第4期248-255,共8页
The authors conducted a retrospective study over a period of 6 months in a hypertensive population in order to determine the correlation between serum uric acid on glomerular filtration rate (GFR) and estimated serum ... The authors conducted a retrospective study over a period of 6 months in a hypertensive population in order to determine the correlation between serum uric acid on glomerular filtration rate (GFR) and estimated serum potassium with left ventricular hypertrophy (LVH) and obesity. This study enrolled 122 patients including 63 women (51.6%). The mean age was 55.9 ± 10.6 years (range 30 to 74 years). Obesity weight was found in 38 cases (31.1%) of which 20?were men (33.9%) and 18 women (28.6%). Abdominal obesity was found in 104 cases (85.2%). The average serum uric acid in patients with obesity weight was 63.3 ± 18.9 mg/L vs 62.4 ± 14.2 mg/L for no-obese patients (p?= 0.63). The average serum potassium in obese patients was 4.06 ± 0.42 mEq/L vs 4.02 ± 0.46 mEq/L for no-obese (p?= 0.65). The average GFR was 73.4 ± 21.4 ml/L in obese patients vs 66.6 ± 22.6 ml/min in no-obese (p?= 0.03). The LVH was found in 81 cases (66.4%). The LVH was found in 65 (62.5%) obese patients vs?16 (88%) non-obese patients (OR = 4.8, 95% 1.04?-?22?p?= 0.02). Only abdominal?obesity has been correlated with left ventricular hypertrophy after multivariate analysis. Emphasis must be focused on public health actions for effective and appropriate measures against obesity and hypertension, whose prevalence is increasing in our region. 展开更多
关键词 OBESITY High blood Pressure Glomerular FILTRATION Rate Uric Acid SERUM POTASSIUM black AFRICAN
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Detection and Analysis of Routine Blood Indexes in Guike Pig 被引量:6
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作者 Qianlian SU Bin LI +9 位作者 Jiaxing LIANG Yingning ZHOU Zhongwei CHEN Yibin QIN Bingxia LU Ying HE Qunpeng DUAN Dongfu JIANG Jingzhuan LU Wu ZHAO 《Agricultural Biotechnology》 CAS 2018年第3期95-98,103,共5页
[Objectives] In this study,routine blood indexes of Guike pig were detected to clarify quantity variation and morphology distribution of different functional cells( red blood cells,white blood cells and platelets),t... [Objectives] In this study,routine blood indexes of Guike pig were detected to clarify quantity variation and morphology distribution of different functional cells( red blood cells,white blood cells and platelets),thus providing reference data for immunological evaluation and disease resistance research of Guike pig. [Methods] Blood samples were collected from forty-four 49-day-old healthy Guike pigs( 22 males and 22 females) once a week for seven consecutive weeks to detect routine blood indexes,and the results were compared with routine blood indexes of Landrace pig and Enshi black pig. [Results]Among red blood cell indexes of Guike pig at different day ages,red blood cell count( RBC) and hemoglobin count( HGB) both reached the lowest levels( 6. 85 × 10^12/L and 97. 1 g/L)at 70 days of age,which were significantly lower than the corresponding indexes at 49,56,63,84 and 91 days of age( P 〈 0. 05,similarly hereinafter); mean corpuscular hemoglobin( MCH) and mean corpuscular hemoglobin concentration( MCHC) demonstrated basically the same variation pattern,which both reached the lowest levels( 15. 11 pg and 275. 70 g/L) at 70 days of age and reached the highest levels( 16. 40 pg and 314. 30 g/L) at 91 days of age; hematocrit( HCT),mean corpuscular volume( MCV) and red blood cell distribution width( RDW) exhibited relatively stable changes with no significant differences among different day ages( P 〉 0. 05,similarly hereinafter). Among white blood cell indexes of Guike pig at different day ages,white blood cell count( WBC) reached the lowest level( 13. 71 × 10^9/L) at 63 days of age and reached the highest level( 17. 52 × 10^9/L) at 84 days of age,with significant differences; neutrophil count( NEUT)reached the lowest level( 3. 61 × 10^9/L) at 70 days of age,which was significantly lower than that at 49,56 and 77 days of age; lymphocyte count( LYMPH) exhibited relatively stable changes and was not significantly affected by the increase in day age. Among platelet indexes of Guike pig at different day ages,platelet count( PLT),thrombocytocrit( PCT) and platelet volume distribution width( PDW) exhibited relatively stable changes among different day ages,which were not significantly affected by the increase in day age. Compared to 35-day-old Landrace pig and 5-month-old Enshi black pig,most routine blood indexes of Guike pig were similar to or ranged between those of Landrace pig and Enshi black pig except HCT,mean platelet volume( MPV),PCT and PDW. [Conclusions]Guike pig has a certain uniqueness in routine blood indexes,which has developed a stable immune system at 49-91 days of age. 展开更多
关键词 Guike pig Landrace pig Enshi black pig Routine blood indexes Detection and analysis
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Effects of <i>Nigella sativa</i>L. Seed Extract on Fatigue, Blood Biochemical Parameters and Thyroid Function in Male Mice
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作者 Azadeh Shariatifar Mahdieh Riazi +1 位作者 Mona Ebnolelm Mahsa Hadipour Jahromy 《Chinese Medicine》 2014年第1期16-21,共6页
Nigella sativa L. (Black seed), is a traditional herbal medicine that has been used for many purposes. The present study was designed to investigate the effects of hydro-alcoholic extract of nigella sativa L. (NS) on ... Nigella sativa L. (Black seed), is a traditional herbal medicine that has been used for many purposes. The present study was designed to investigate the effects of hydro-alcoholic extract of nigella sativa L. (NS) on performance of Forced Swimming Test (FST), blood biochemical parameters related to fatigue and thyroid functions. Therefore, Blood Urea Nitrogen (BUN), Creatine Kinase (CK), Lactic Dehydrogenase (LDH), and Total Protein (TP), triiodothyronine T3, thyroxin T4 and TSH tests were investigated. Thirty five male adult mice were randomly divided into five groups: three NS-fed groups, one fluoxetine treated group and one control group. Three NS experimental groups received hydro-alcoholic extract of NS at doses of 50, 100 and 200 mg/kg orally for two weeks. Immobility time decreased in all NS groups compared with control group. Administration of NS significantly increased the concentration of T3 and T4 of the treatment groups. On the contrary, the amount of BUN, CK, LDH, TP and TSH decreased. In conclusion, black seed extract at the experimented doses showed anti-depressant, anti-fatigue and hyperthyroid effects. 展开更多
关键词 Nigella sativa Hydro-Alcoholic EXTRACT black SEED Thyroid Functions Forced Swimming Test blood Biochemical Parameters Related to FATIGUE
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高分辨MRI 3D黑血技术及CT血管成像在急性缺血性脑卒中的应用价值 被引量:2
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作者 高宗露 秦伟英 《中国实用神经疾病杂志》 2024年第4期409-414,共6页
目的 探究高分辨磁共振成像(MRI)3D黑血技术与CT血管成像(CTA)在急性缺血性脑卒中患者中的应用价值。方法 选取2020-01—2022-12江苏省中西医结合医院的急性缺血性脑卒中患者102例为研究对象,所有患者接受颈部高分辨MRI 3D黑血技术及CT... 目的 探究高分辨磁共振成像(MRI)3D黑血技术与CT血管成像(CTA)在急性缺血性脑卒中患者中的应用价值。方法 选取2020-01—2022-12江苏省中西医结合医院的急性缺血性脑卒中患者102例为研究对象,所有患者接受颈部高分辨MRI 3D黑血技术及CTA扫描,比较不同检查方法所得管腔面积、管壁面积、管壁外界面积。以数字减影血管造影(DSA)为金标准,分析高分辨MRI 3D黑血技术及CTA对缺血性脑卒中患者血管狭窄、溃疡斑块的诊断价值。结果 高分辨MRI 3D黑血技术与CTA所测管腔面积、管壁面积、管壁外界面积比较差异无统计学意义(P>0.05)。以DSA为金标准,高分辨MRI 3D黑血技术诊断血管狭窄>70%真阳性62例,假阳性2例,真阴性35例,假阴性3例;CTA诊断真阳性62例,假阳性3例,真阴性34例,假阴性3例。两种方式诊断特异度、敏感度、准确度比较无统计学差异(P>0.05)。高分辨MRI 3D黑血技术诊断溃疡斑块真阳性49例,假阳性1例,真阴性50例,假阴性2例;CTA诊断真阳性38例,假阳性17例,真阴性35例,假阴性12例。高分辨MRI 3D黑血技术诊断溃疡斑块特异度、敏感度、准确度高于CTA(P<0.05)。结论 两种检查方式对急性缺血性脑卒中患者颈动脉狭窄的诊断均有较高参考价值,高分辨MRI 3D黑血技术对于溃疡斑块的诊断参考价值更高。 展开更多
关键词 急性缺血性脑卒中 高分辨磁共振成像 3D黑血技术 CT血管成像 诊断价值
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血浆脂蛋白琼脂糖凝胶电泳综合实验设计
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作者 冯俊荣 唐永政 高慧鑫 《广州化工》 CAS 2024年第13期162-164,共3页
血浆脂蛋白琼脂糖凝胶电泳实验是生物化学实验课程中的经典实验,但因其操作单一、等待时间过长,学生的收获感不强,有必要进行综合设计。把上课时间分为三个时段,在各个时段设计多种学习活动:串讲原理、做练习题使相关知识融会贯通;阅读... 血浆脂蛋白琼脂糖凝胶电泳实验是生物化学实验课程中的经典实验,但因其操作单一、等待时间过长,学生的收获感不强,有必要进行综合设计。把上课时间分为三个时段,在各个时段设计多种学习活动:串讲原理、做练习题使相关知识融会贯通;阅读文献,提出疑问;设置试误样品组、做相关实验,启发学生顿悟。通过这些学习活动,学生不仅学会了电泳技术的基本操作,还深刻理解了实验原理,强化了勇于探索的科学精神,体会了顿悟的快乐。 展开更多
关键词 血浆脂蛋白 琼脂糖凝胶电泳 苏丹黑 综合实验设计 试误教学
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影响氨基黑10B显现指纹因素的系统探究 被引量:1
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作者 丁远 刘丽 胡语嫣 《化学世界》 2024年第1期55-59,共5页
指纹是犯罪现场的最常见物证之一,更是对犯罪嫌疑人或受害人进行同一认证的重要物证,而由于犯罪现场的复杂性,不同的环境因素会对指纹的显现结果造成影响。以瓷砖上的新鲜血手印这一室内凶案现场常见的指纹物证为研究对象,探究了不同因... 指纹是犯罪现场的最常见物证之一,更是对犯罪嫌疑人或受害人进行同一认证的重要物证,而由于犯罪现场的复杂性,不同的环境因素会对指纹的显现结果造成影响。以瓷砖上的新鲜血手印这一室内凶案现场常见的指纹物证为研究对象,探究了不同因素对氨基黑10B显现液显现指纹的影响,表明质量分数为0.60%氨基黑10B,质量分数为25%冰乙酸的显现液是显现瓷砖上新鲜血潜手印的最佳配方,同时,该配方也适用于不同显现方法、不同承痕客体、不同浓度和不同遗留时间的血手印和显现含有蛋白质的指纹。 展开更多
关键词 氨基黑10B 手印显现 血潜手印
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黑磷纳米片在帕金森病中的治疗作用
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作者 袁佳丽 张春林 雷莉 《中国生物化学与分子生物学报》 CAS CSCD 北大核心 2024年第8期1112-1118,共7页
帕金森病是一种中枢神经系统变性疾病,为多基因遗传。因中脑多巴胺代谢失调而引起运动障碍等症状。目前,尽管用于治疗帕金森病的药物是针对该疾病发病机制开发的,但是由于在血脑屏障渗透性方面仍存在着一定的缺陷,导致这些药物的治疗效... 帕金森病是一种中枢神经系统变性疾病,为多基因遗传。因中脑多巴胺代谢失调而引起运动障碍等症状。目前,尽管用于治疗帕金森病的药物是针对该疾病发病机制开发的,但是由于在血脑屏障渗透性方面仍存在着一定的缺陷,导致这些药物的治疗效果不佳。纳米材料为帕金森病的药物治疗提供了解决方案,能够将药物靶向到特定区域,解决药物缺乏特定部位的递送问题。纳米材料具有独特的物理化学特性,可以通过不同的机制穿越血脑屏障。最新研究表明,携带纳米载体和合适配体的治疗药物,有助于改善亲、疏水性药物在大脑中的分布,实现特定部位的药物递送。黑磷是近5年备受关注的新型纳米材料,因其独特结构赋予的性能,包括优越的光热/光动力特性、还原性、高载药能力以及良好的生物相容性等,被广泛应用于生物医药领域研究。在这篇综述中,我们将介绍帕金森病的病理机制以及黑磷纳米片在帕金森病治疗中的适用性。 展开更多
关键词 帕金森病 黑磷纳米片 血脑屏障 神经保护作用
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流动敏感黑血序列三维T_(1)WI增强扫描在脑转移瘤中的应用价值
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作者 冉红芹 向正东 +3 位作者 段庆红 陈振涛 徐军 杨洁 《放射学实践》 CSCD 北大核心 2024年第2期169-174,共6页
目的:探讨3.0T磁共振流动敏感黑血序列三维T_(1)加权增强扫描(FSBB 3D CE-T_(1)WI)在脑转移瘤中的应用价值。方法:回顾性将2021年1月-2022年8月在本院就诊且经临床和影像检查证实的52例脑转移患者纳入研究。所有患者分别行颅脑FSBB 3D C... 目的:探讨3.0T磁共振流动敏感黑血序列三维T_(1)加权增强扫描(FSBB 3D CE-T_(1)WI)在脑转移瘤中的应用价值。方法:回顾性将2021年1月-2022年8月在本院就诊且经临床和影像检查证实的52例脑转移患者纳入研究。所有患者分别行颅脑FSBB 3D CE-T_(1)WI、FSE CE-T_(1)WI和快速梯度回波序列三维T_(1)加权对比增强(FFE 3D CE-T_(1)WI)扫描,采用卡方检验或Fisher精确概率检验比较3个序列之间病灶检出率的差异。结果:经随访证实颅内转移灶总数为371个,FSBB 3D CE-T_(1)WI的检出率99.73%(370/371),FFE 3D CE-T_(1)WI的检出率为83.02%(308/371),FSE CE-T_(1)WI的检出率为78.44%(291/371),三者之间检出率的差异有统计学意义(χ^(2)=82.748,P<0.05)。分层分析:直径<3 mm的转移灶共160个,FSE CE-T_(1)WI、FFE 3D CE-T_(1)WI和FSBB 3D CE-T_(1)WI的检出率分别为50.62%、60.62%和99.37%,三个序列之间检出率的差异有统计学意义(χ^(2)=101.436,P<0.05);对于直径3~10 mm的转移灶,FSE CE-T_(1)WI、FFE 3D CE-T_(1)WI和FSBB 3D CE-T_(1)WI的检出率分别为99.38%、100%和100%,三个序列之间检出率的差异无统计学意义(P>0.05);对直径>10 mm的转移灶,三个序列的检出率均为100%,差异无统计学意义(P>0.05)。结论:FSBB 3D CE-T_(1)WI在检出脑转移瘤方面要优于常规和高分辨序列MR增强扫描,值得临床推广。 展开更多
关键词 脑转移瘤 流动敏感黑血序列 对比增强 磁共振成像
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菌草灵芝多糖肽对闽西南黑兔生长性能、血液生化指标及免疫机能的影响 被引量:2
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作者 覃娟清 杜志坚 +3 位作者 张富 秦莉雯 郭宇康 刘庆华 《西北农林科技大学学报(自然科学版)》 CSCD 北大核心 2024年第4期49-56,84,共9页
【目的】研究日粮中添加菌草灵芝多糖肽(JCGLPP)对闽西南黑兔生长性能、血液生化指标及免疫功能的影响,为JCGLPP在肉兔中的应用提供依据。【方法】选取(33±2)d、初始体质量(655.65±25.90)g、健康状况良好的断奶闽西南黑兔公兔... 【目的】研究日粮中添加菌草灵芝多糖肽(JCGLPP)对闽西南黑兔生长性能、血液生化指标及免疫功能的影响,为JCGLPP在肉兔中的应用提供依据。【方法】选取(33±2)d、初始体质量(655.65±25.90)g、健康状况良好的断奶闽西南黑兔公兔100只,随机分为4组,对照组饲喂基础饲粮,试验Ⅰ、Ⅱ、Ⅲ组分别饲喂在基础饲粮中添加50,100和150 mg/kg JCGLPP的日粮,56 d后统计腹泻率和死亡率,测算平均日采食量(ADFI)、平均日增重(ADG)以及料重比(F/G);屠宰后取背腰最长肌,测定pH值、滴水损失率和剪切力;采集血清,测定总蛋白(TP)、白蛋白(ALB)质量浓度,尿素氮(UN)、丙二醛(MDA)浓度,超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性以及IgG、IgA、IgM和IL-6质量浓度;计算心脏、肝脏、肾脏、圆小囊、脾脏、胸腺和蚓突器官指数;测定十二指肠、空肠、回肠黏膜炎性因子IL-1α、IL-2和分泌型免疫球蛋白(sIgA)质量浓度及肠道淀粉酶、纤维素酶和胰蛋白酶活性。【结果】①各组间兔的终末体质量、平均日增重、平均采食量和料重比均无显著差异(P>0.05);对照组兔的腹泻率和死亡率最高,Ⅱ组兔的腹泻率显著低于对照(P<0.05)。②试验组兔肌肉的pH、滴水损失和剪切力均与对照无显著差异(P>0.05)。③Ⅱ组兔血液中的TP、ALB质量浓度及SOD、GSH-Px活性显著高于对照(P<0.05),而UN和MDA浓度显著低于对照(P<0.05)。④Ⅱ组兔血液中的IgG、IgA、IgM质量浓度均显著高于对照(P<0.05),而IL-6质量浓度各组差异不显著(P>0.05)。⑤各组兔免疫器官指数差异均不显著(P>0.05);试验组兔十二指肠、空肠、回肠IL-1α、IL-2和sIgA质量浓度大多显著高于对照(P<0.05),肠道淀粉酶活性均显著低于对照(P<0.05),Ⅰ组兔的肠道纤维素酶和胰蛋白酶活性、Ⅱ组兔的肠道胰蛋白酶活性显著高于对照(P<0.05)。【结论】JCGLPP对闽西南黑兔的促生长作用不明显,但能提高机体的抗氧化和免疫能力,降低腹泻率和死亡率,添加量以100 mg/kg为宜。 展开更多
关键词 闽西南黑兔 菌草灵芝多糖肽 生长性能 血液生化指标 免疫机能
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不同饲养方式对乌骨鸡生长性能和血液生化指标的影响
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作者 李世新 邵淑娟 +4 位作者 李洁 朱彤 刘彩燕 何钦 李谨 《现代畜牧兽医》 2024年第9期42-45,共4页
为探究不同饲养方式对乌骨鸡生长性能和血液生化指标的影响,试验选择240羽10周龄、体重相近、健康无病的白羽乌骨鸡,随机分为果林散养和笼养两组,每组3个重复,每个重复40只鸡。试验期10周。结果显示:果林散养组试验鸡末重显著低于笼养组... 为探究不同饲养方式对乌骨鸡生长性能和血液生化指标的影响,试验选择240羽10周龄、体重相近、健康无病的白羽乌骨鸡,随机分为果林散养和笼养两组,每组3个重复,每个重复40只鸡。试验期10周。结果显示:果林散养组试验鸡末重显著低于笼养组(P<0.05),平均日增重低于笼养组(P>0.05)。果林散养组乌骨鸡血液总蛋白(TP)含量和淀粉酶(AMY)活性显著高于笼养组(P<0.05),球蛋白(GLB)、尿素氮(BUN)、葡萄糖(GLU)的含量及天门冬氨酸转移酶(AST)活性高于笼养组(P>0.05),甘油三酯(TG)含量显著低于笼养组(P<0.05),白蛋白(ALB)、总胆红素(TBIL)的含量及丙氨酸氨基转移酶(ALT)、肌酸激酶(CK)的活性低于笼养组(P>0.05)。结果显示,与笼养相比,果林散养不利于乌骨鸡体重增长,但对乌骨鸡的健康状况具有一定改善作用。 展开更多
关键词 乌骨鸡 饲养方式 生长性能 血液生化指标
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荷叶大豆及其合剂调脂活性部位的研究 被引量:105
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作者 杜力军 孙虹 +2 位作者 李敏 金文 徐丽珍 《中草药》 CAS CSCD 北大核心 2000年第7期526-528,共3页
目的 :通过体内外实验探讨荷叶大豆调脂的活性部位及其作用特点。方法 :以急性高脂血症小鼠为整体模型观察药物对血清胆固醇及甘油三酯的影响。体外给药观察药物对肝细胞合成胆固醇的影响。结果 :荷叶大豆的水提取部分及其生物碱和黄酮... 目的 :通过体内外实验探讨荷叶大豆调脂的活性部位及其作用特点。方法 :以急性高脂血症小鼠为整体模型观察药物对血清胆固醇及甘油三酯的影响。体外给药观察药物对肝细胞合成胆固醇的影响。结果 :荷叶大豆的水提取部分及其生物碱和黄酮均有调脂作用。大豆黄酮对体外肝细胞合成胆固醇有抑制的趋势。结论 :荷叶和大豆均有调脂作用 ,其主要活性部位在黄酮和生物碱 ,其作用特点在于促进胆固醇的代谢方面。 展开更多
关键词 荷叶 大豆 调血脂 中药合剂 高脂血症 小鼠
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高分辨3D黑血磁共振定量评价颈动脉粥样硬化斑块 被引量:21
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作者 刘丹青 王庆军 +3 位作者 蔡剑鸣 蔡幼铨 王勇 韩旭 《南方医科大学学报》 CAS CSCD 北大核心 2013年第3期365-369,共5页
目的通过与高分辨2D黑血磁共振成像技术比较,评价3D黑血磁共振成像(3D-BB-MRI)对颈动脉粥样硬化斑块定量分析的价值。方法 40例患者进行颈动脉常规轴位2D-BB-MRI及斜矢状位3D-BB-MRI扫描。对斜矢状位3D-BB-MRI原始图像进行轴位重建。对... 目的通过与高分辨2D黑血磁共振成像技术比较,评价3D黑血磁共振成像(3D-BB-MRI)对颈动脉粥样硬化斑块定量分析的价值。方法 40例患者进行颈动脉常规轴位2D-BB-MRI及斜矢状位3D-BB-MRI扫描。对斜矢状位3D-BB-MRI原始图像进行轴位重建。对于每个测量对象(单侧颈动脉),由两名有经验的放射科医师在2D-BB-MRI图像上共同找出其斑块测量的兴趣层面,以此进行3D-BB-MRI轴位重建图像与2D-BB-MRI图像的匹配。对该侧颈动脉分别进行斑块厚度、管腔狭窄程度、管腔面积、总血管面积的测量及管壁面积和标准化管壁指数的计算,并分析所有数据。结果在评估斑块厚度、管腔狭窄程度、管腔面积、总血管面积、管壁面积及标准化管壁指数方面,2D-BB-MRI与3D-BB-MRI轴位重建图像的测量差异无统计学意义(P>0.05),两者呈较强的相关性(r>0.9)。Bland-Altman图显示对于测量斑块厚度、管腔面积、总血管面积,2D-BB-MRI与3D-BB-MRI两种方法具有良好的一致性。结论 3D-BB-MRI和2D-BB-MRI对于定量评价颈动脉粥样硬化斑块方面无明显差异;3D-BB-MRI具有任意角度重建图像、灵活显示管壁及斑块情况的特点,我们认为3D-BB-MRI对于颈动脉粥样硬化成像较2D-BB-MRI具有更好的发展前景。 展开更多
关键词 高分辨黑血磁共振成像技术 颈动脉粥样硬化 斑块
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高分辨率核磁黑血成像技术评估颅内静脉及静脉窦血栓形成病程分期的价值 被引量:20
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作者 杨旗 杨晓旭 +5 位作者 段祥攻 吴芳 武晔 杜祥颖 段建钢 吉训明 《中国脑血管病杂志》 CAS CSCD 北大核心 2017年第8期420-423,共4页
目的应用高分辨率MR黑血血栓成像(BTI)技术评价颅内静脉及静脉窦血栓形成(CVT)在病程分期中的价值。方法前瞻性纳入2015年6月至2016年10月首都医科大学宣武医院37例常规影像学检查确诊为CVT的患者,均另行BTI检查。根据临床症状出现至BT... 目的应用高分辨率MR黑血血栓成像(BTI)技术评价颅内静脉及静脉窦血栓形成(CVT)在病程分期中的价值。方法前瞻性纳入2015年6月至2016年10月首都医科大学宣武医院37例常规影像学检查确诊为CVT的患者,均另行BTI检查。根据临床症状出现至BTI检查时间,将患者分为急性组(≤14 d,23例)和慢性组(>15 d,14例)。测量BTI图像上检测到的血栓信号噪声比(SNR)和对比噪声比(CNR),比较两组血栓信号的差异。以MR静脉成像(MRV)检查结果作为参照,计算血管节段水平BTI诊断的准确性。结果 (1)血栓SNR在急性组和慢性组分别为206±97和94±41,CNR为201±96和86±40,两组比较差异有统计学意义(t值分别为4.9和5.0,均P<0.01)。(2)37例CVT患者中,MRV共检出159处脑静脉及静脉窦节段存在血栓,BTI在其中152处准确识别血栓,在352处排除血栓,诊断敏感度和特异度分别为95.6%(152/159)和98.0%(352/359)。结论 BTI技术实现脑静脉血栓直接成像,能够准确区分急性与慢性血栓,具有较高准确性。 展开更多
关键词 脑静脉及静脉窦血栓 磁共振成像 黑血血栓成像 颅内静脉血栓分期
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贵州黑山羊母羊部分血液生理指标的测定与分析 被引量:16
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作者 田兴贵 朱红刚 +4 位作者 主性 潘顺本 吴飞 冯会利 刘若余 《西南农业学报》 CSCD 北大核心 2011年第1期366-368,共3页
为黑山羊品种的选育及临床珍断提供参考依据,测定了5月龄、8月龄、1岁、2岁和3岁贵州黑山羊母羊的15项血液生理指标。结果表明:5个年龄段的白细胞中单核细胞数量(MON)、平均红细胞体积(MCV)、平均红细胞血红蛋白含量(MCH)、平均红细胞... 为黑山羊品种的选育及临床珍断提供参考依据,测定了5月龄、8月龄、1岁、2岁和3岁贵州黑山羊母羊的15项血液生理指标。结果表明:5个年龄段的白细胞中单核细胞数量(MON)、平均红细胞体积(MCV)、平均红细胞血红蛋白含量(MCH)、平均红细胞血红蛋白浓度(MCHC)、平均血小板体积(MPV)、血小板体积分布宽度(PDW)等6项指标无显著性差异,其他9个血液生理指标在不同年龄间存在一定的差异。但各年龄段的血液生理指标与平均值相比,除8月龄的白细胞中淋巴细胞数量(LYM)、3岁的血红蛋白浓度(HGB)和1岁的白细胞中中性粒细胞比率(GRA%)外,其他指标间无显著性差异。所测定的15项血液生理指标的平均值可作为贵州黑山羊的正常血液生理指标。 展开更多
关键词 贵州黑山羊 血液 生理指标 分析
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磁共振黑血序列冠状动脉管壁成像评价粥样硬化斑块初步研究结果:与血管内超声对照研究 被引量:9
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作者 张兆琪 贺毅 +2 位作者 戴沁怡 于薇 李勐 《磁共振成像》 CAS 2010年第2期94-97,共4页
目的与血管内超声(IVUS)对照,探讨磁共振黑血序列冠状动脉管壁成像评价冠状动脉斑块的可行性及准确性。方法拟行IVUS检查及行IVUS检查而未行支架植入术的患者11例,分别于IVUS术前及术后10日内行磁共振检查。成像序列采用二维横截面、双... 目的与血管内超声(IVUS)对照,探讨磁共振黑血序列冠状动脉管壁成像评价冠状动脉斑块的可行性及准确性。方法拟行IVUS检查及行IVUS检查而未行支架植入术的患者11例,分别于IVUS术前及术后10日内行磁共振检查。成像序列采用二维横截面、双反转恢复、呼吸导航心电门控触发、压脂TSE序列,采集自病变冠脉开口至中段无间隔连续扫描,测量以下数据:血管横截面积(CSA)、管腔CSA、斑块负荷、管壁信噪比(SNR)及对比噪声比(CNR)。在IVUS上将靶冠脉自开口分为每5mm节段,与MRI管壁横截面一一对应。当冠状动脉管壁厚度≥0.5mm时考虑存在斑块。结果共9例病人,9支冠脉,37个层面纳入分析;2例病人被排除(因扫描时间长,病人无法坚持),扫描成功率82%。37个层面中有20个有斑块。斑块层面的斑块负荷、SNR、CNR大于非斑块层面(分别为0.70±0.11vs0.58±0.14,1.95±0.39vs1.48±0.21,5.47±2.06vs2.99±0.78,P<0.05)。MRI斑块层面血管CSA、管腔CSA及斑块负荷与IVUS比较,具有良好的相关性(13.66±4.52vs14.92±6.37,4.62±2.23vs6.03±3.85,0.63±0.13vs0.60±0.14,P<0.05)。结论冠状动脉黑血管壁成像可以发现冠状动脉近中段的粥样硬化斑块,且能够相对评价狭窄段血管面积和管腔面积。 展开更多
关键词 磁共振成像 冠状动脉 管壁成像 黑血 血管内超声
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