To establish the parsimonious model for blood glucose monitoring in patients with type 2 diabetes receiving oral hypoglycemic agent treatment. One hundred and fifty-nine adult Chinese type 2 diabetes patients were ran...To establish the parsimonious model for blood glucose monitoring in patients with type 2 diabetes receiving oral hypoglycemic agent treatment. One hundred and fifty-nine adult Chinese type 2 diabetes patients were randomized to receive rapid-acting or sustained-release gliclazide therapy for 12 weeks.展开更多
Introduction: Diabetes mellitus type 2 is a growing threat in developing countries already burdened with high levels of infectious disease. Screening the general population has debatable advantages. This study aims to...Introduction: Diabetes mellitus type 2 is a growing threat in developing countries already burdened with high levels of infectious disease. Screening the general population has debatable advantages. This study aims to determine whether spouses of patients with diabetes mellitus have higher random blood glucose (RBG) levels as well as the benefit of RBG testing as a targetted screening tool. Methodology: The survey employed a cross-sectional comparative study of spouses’ of diabetics and non-diabetics attending the general out-patient department of the LagosStateUniversityTeaching Hospital (LASUTH), Ikeja. A modified WHO STEPS Surveillance Instrument and a one-touch Glucometer were used to collect data. Blood pressures and BMI were measured and correlated to blood glucose levels. Results: Prevalence of high RBG was found to be 7% among spouses of diabetics and 3.3% among spouses of non-diabetic patients. Mean RBG was 5.57 mmol/L and 7.7 mmol/L within the age group 40 - 49 years and 50 - 59 years respectively among spouses of diabetic patients compared to 5.4 mmol/L and 5.5 mmol/L within the same age group among the spouses non-diabetics. Spouses of patients with diabetes mellitus had higher systolic and diastolic blood pressures and BMI compared to spouses of non-diabetics. Conclusion: Being male, married to a diabetic patient, lower educational levels and higher body mass index are significantly associated with higher random blood glucose in the spouses of diabetic patients. Random blood glucose measurements are an effective screening tool and spouses of diabetic patients can benefit from targeted screening in controlled clinical settings.展开更多
Background: The aim of the current study was to evaluate the anthropometric and demographic factors and their correlation with type 2 diabetes mellitus (T2DM) in Bangladesh. Methods: One hundred fourteen patients (70 ...Background: The aim of the current study was to evaluate the anthropometric and demographic factors and their correlation with type 2 diabetes mellitus (T2DM) in Bangladesh. Methods: One hundred fourteen patients (70 males and 44 females) between 30 and 75 years of age from various areas of Bangladesh were screened for T2DM. Fasting blood sugar (FBS) was analyzed by using laboratory kits and spectrophotometric technique. Anthropometric and socio-demographic data were collected using a structured questionnaire. Body mass index (BMI) was calculated from weight (kg) and height (m) of the individual respondents. Physical activity was categorized based on activity during daily work. Economic condition is defined by respective family income and education level is categorized into 3 levels: illiterate, 0 - 12 years of education and graduate or above. Results: According to the current study results, half of the patients were from the middle-class family with low physical activity and their age was within the range of 30 - 45 years. The male and female ratio of the study population was 60:40. Most of the patients were found to be obese and educated. Urban populations were more prone to have DM than the rural population. Age, education, the area of residence (urban and rural), physical activity and co-morbid diseases were significantly correlated with T2DM in Bangladesh (P Conclusion: Our study shows that different socio-demographic factors have a significant correlation with T2DM in Bangladesh. Diabetes awareness, early diagnosis, patient education and life-style modification can be initiated to manage T2DM efficiently.展开更多
目的分析恩格列净治疗2型糖尿病合并心力衰竭(心衰)的疗效。方法128例2型糖尿病合并心衰患者,采用信封抽签分组方法分为对照组与观察组,每组64例。对照组应用二甲双胍治疗,观察组应用恩格列净治疗。比较两组患者治疗前后餐后2 h血糖(2 h...目的分析恩格列净治疗2型糖尿病合并心力衰竭(心衰)的疗效。方法128例2型糖尿病合并心衰患者,采用信封抽签分组方法分为对照组与观察组,每组64例。对照组应用二甲双胍治疗,观察组应用恩格列净治疗。比较两组患者治疗前后餐后2 h血糖(2 h PBG)、空腹血糖(FPG)、糖化血红蛋白(HbA1c)、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、C反应蛋白(CRP)、左心室射血分数(LVEF)、左心室收缩末期容积(LVESV)、左心室舒张末期容积(LVEDV)、左心室舒张末期内径(LVEDD)、6 min步行试验距离(6MWD)、N末端B型钠尿肽前体(NT-proBNP)水平。结果治疗后,两组患者2 h PBG、FPG、HbA1c水平均明显降低,且观察组患者2 h PBG(7.26±1.22)mmol/L、FPG(5.97±0.48)mmol/L、HbA1c(6.53±0.67)%均低于对照组的(9.84±2.07)mmol/L、(7.24±0.85)mmol/L、(7.75±0.83)%,具有统计学差异(P<0.05)。治疗后,观察组和对照组患者的TNF-α、IL-6、CRP水平均明显降低,且观察组患者TNF-α(31.55±7.84)pg/ml、IL-6(68.35±9.32)pg/ml、CRP(5.09±1.25)mg/L均低于对照组的(43.23±10.45)pg/ml、(80.78±12.67)pg/ml、(6.18±1.46)mg/L,有统计学差异(P<0.05)。治疗后,两组患者的LVEF、LVESV、LVEDV、LVEDD、6MWD水平较治疗前均明显改善,且观察组患者LVEF(60.18±8.47)%、6MWD(427.20±24.54)m、LVESV(42.24±6.29)ml、LVEDV(81.31±6.54)ml、LVEDD(46.29±4.78)mm均优于对照组的(56.24±6.48)%、(405.42±11.43)m、(47.93±7.65)ml、(88.32±7.54)ml、(49.31±5.54)mm,有统计学差异(P<0.05)。治疗后,两组患者的NT-proBNP水平均明显降低,且观察组患者NT-proBNP(1577.59±625.63)pg/ml低于对照组的(2248.32±939.85)pg/ml,有统计学差异(P<0.05)。结论2型糖尿病合并心衰患者采用恩格列净治疗可显著降低患者血糖水平,也有助于改善心脏功能,是此类患者具有临床价值的用药选择。展开更多
目的:探析以自我管理为导向的5A护理联合人文关怀在老年2型糖尿病(T2DM)患者中的实施效果。方法:选取2021年1月—2022年12月福建中医药大学附属人民医院收治的84例T2DM患者作为研究对象,根据随机数表法将其分为对照组和观察组,各42例。...目的:探析以自我管理为导向的5A护理联合人文关怀在老年2型糖尿病(T2DM)患者中的实施效果。方法:选取2021年1月—2022年12月福建中医药大学附属人民医院收治的84例T2DM患者作为研究对象,根据随机数表法将其分为对照组和观察组,各42例。对照组给予常规护理,观察组实施以自我管理为导向的5A护理联合人文关怀,比较两组血糖水平、自我管理能力及护理满意度。结果:护理前,两组空腹血糖(FBG)、餐后2 h血糖(2 h PG)水平比较,差异无统计学意义(P>0.05);护理后,两组FBG、2 h PG水平低于护理前,且观察组低于对照组,差异有统计学意义(P<0.05)。护理前,两组糖尿病自我管理行为量表(SDSCA)各维度评分比较,差异无统计学意义(P>0.05);护理后,两组SDSCA量表各维度评分高于护理前,且观察组高于对照组,差异有统计学意义(P<0.05);观察组护理总满意度为95.24%,高于对照组的80.95%,差异有统计学意义(P<0.05)。结论:老年T2DM患者实施以自我管理为导向的5A护理联合人文关怀,可更好地控制血糖水平,且能有效提升患者自我管理能力及对护理服务的满意度。展开更多
文摘To establish the parsimonious model for blood glucose monitoring in patients with type 2 diabetes receiving oral hypoglycemic agent treatment. One hundred and fifty-nine adult Chinese type 2 diabetes patients were randomized to receive rapid-acting or sustained-release gliclazide therapy for 12 weeks.
文摘Introduction: Diabetes mellitus type 2 is a growing threat in developing countries already burdened with high levels of infectious disease. Screening the general population has debatable advantages. This study aims to determine whether spouses of patients with diabetes mellitus have higher random blood glucose (RBG) levels as well as the benefit of RBG testing as a targetted screening tool. Methodology: The survey employed a cross-sectional comparative study of spouses’ of diabetics and non-diabetics attending the general out-patient department of the LagosStateUniversityTeaching Hospital (LASUTH), Ikeja. A modified WHO STEPS Surveillance Instrument and a one-touch Glucometer were used to collect data. Blood pressures and BMI were measured and correlated to blood glucose levels. Results: Prevalence of high RBG was found to be 7% among spouses of diabetics and 3.3% among spouses of non-diabetic patients. Mean RBG was 5.57 mmol/L and 7.7 mmol/L within the age group 40 - 49 years and 50 - 59 years respectively among spouses of diabetic patients compared to 5.4 mmol/L and 5.5 mmol/L within the same age group among the spouses non-diabetics. Spouses of patients with diabetes mellitus had higher systolic and diastolic blood pressures and BMI compared to spouses of non-diabetics. Conclusion: Being male, married to a diabetic patient, lower educational levels and higher body mass index are significantly associated with higher random blood glucose in the spouses of diabetic patients. Random blood glucose measurements are an effective screening tool and spouses of diabetic patients can benefit from targeted screening in controlled clinical settings.
文摘Background: The aim of the current study was to evaluate the anthropometric and demographic factors and their correlation with type 2 diabetes mellitus (T2DM) in Bangladesh. Methods: One hundred fourteen patients (70 males and 44 females) between 30 and 75 years of age from various areas of Bangladesh were screened for T2DM. Fasting blood sugar (FBS) was analyzed by using laboratory kits and spectrophotometric technique. Anthropometric and socio-demographic data were collected using a structured questionnaire. Body mass index (BMI) was calculated from weight (kg) and height (m) of the individual respondents. Physical activity was categorized based on activity during daily work. Economic condition is defined by respective family income and education level is categorized into 3 levels: illiterate, 0 - 12 years of education and graduate or above. Results: According to the current study results, half of the patients were from the middle-class family with low physical activity and their age was within the range of 30 - 45 years. The male and female ratio of the study population was 60:40. Most of the patients were found to be obese and educated. Urban populations were more prone to have DM than the rural population. Age, education, the area of residence (urban and rural), physical activity and co-morbid diseases were significantly correlated with T2DM in Bangladesh (P Conclusion: Our study shows that different socio-demographic factors have a significant correlation with T2DM in Bangladesh. Diabetes awareness, early diagnosis, patient education and life-style modification can be initiated to manage T2DM efficiently.
文摘目的分析恩格列净治疗2型糖尿病合并心力衰竭(心衰)的疗效。方法128例2型糖尿病合并心衰患者,采用信封抽签分组方法分为对照组与观察组,每组64例。对照组应用二甲双胍治疗,观察组应用恩格列净治疗。比较两组患者治疗前后餐后2 h血糖(2 h PBG)、空腹血糖(FPG)、糖化血红蛋白(HbA1c)、肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、C反应蛋白(CRP)、左心室射血分数(LVEF)、左心室收缩末期容积(LVESV)、左心室舒张末期容积(LVEDV)、左心室舒张末期内径(LVEDD)、6 min步行试验距离(6MWD)、N末端B型钠尿肽前体(NT-proBNP)水平。结果治疗后,两组患者2 h PBG、FPG、HbA1c水平均明显降低,且观察组患者2 h PBG(7.26±1.22)mmol/L、FPG(5.97±0.48)mmol/L、HbA1c(6.53±0.67)%均低于对照组的(9.84±2.07)mmol/L、(7.24±0.85)mmol/L、(7.75±0.83)%,具有统计学差异(P<0.05)。治疗后,观察组和对照组患者的TNF-α、IL-6、CRP水平均明显降低,且观察组患者TNF-α(31.55±7.84)pg/ml、IL-6(68.35±9.32)pg/ml、CRP(5.09±1.25)mg/L均低于对照组的(43.23±10.45)pg/ml、(80.78±12.67)pg/ml、(6.18±1.46)mg/L,有统计学差异(P<0.05)。治疗后,两组患者的LVEF、LVESV、LVEDV、LVEDD、6MWD水平较治疗前均明显改善,且观察组患者LVEF(60.18±8.47)%、6MWD(427.20±24.54)m、LVESV(42.24±6.29)ml、LVEDV(81.31±6.54)ml、LVEDD(46.29±4.78)mm均优于对照组的(56.24±6.48)%、(405.42±11.43)m、(47.93±7.65)ml、(88.32±7.54)ml、(49.31±5.54)mm,有统计学差异(P<0.05)。治疗后,两组患者的NT-proBNP水平均明显降低,且观察组患者NT-proBNP(1577.59±625.63)pg/ml低于对照组的(2248.32±939.85)pg/ml,有统计学差异(P<0.05)。结论2型糖尿病合并心衰患者采用恩格列净治疗可显著降低患者血糖水平,也有助于改善心脏功能,是此类患者具有临床价值的用药选择。
文摘目的:探析以自我管理为导向的5A护理联合人文关怀在老年2型糖尿病(T2DM)患者中的实施效果。方法:选取2021年1月—2022年12月福建中医药大学附属人民医院收治的84例T2DM患者作为研究对象,根据随机数表法将其分为对照组和观察组,各42例。对照组给予常规护理,观察组实施以自我管理为导向的5A护理联合人文关怀,比较两组血糖水平、自我管理能力及护理满意度。结果:护理前,两组空腹血糖(FBG)、餐后2 h血糖(2 h PG)水平比较,差异无统计学意义(P>0.05);护理后,两组FBG、2 h PG水平低于护理前,且观察组低于对照组,差异有统计学意义(P<0.05)。护理前,两组糖尿病自我管理行为量表(SDSCA)各维度评分比较,差异无统计学意义(P>0.05);护理后,两组SDSCA量表各维度评分高于护理前,且观察组高于对照组,差异有统计学意义(P<0.05);观察组护理总满意度为95.24%,高于对照组的80.95%,差异有统计学意义(P<0.05)。结论:老年T2DM患者实施以自我管理为导向的5A护理联合人文关怀,可更好地控制血糖水平,且能有效提升患者自我管理能力及对护理服务的满意度。
