Impacts of acupuncture on brainstem evoked potentials in patients with primary depression

Objective To observe the impacts of acupuncture on brainstem evoked potentials in the patients with primary depression. Methods Forty cases of primary depression were treated by acupuncture at Baihui （百会 GV 20）, Yinatng （印堂 GV 29）, DazhuT （大椎 GV 14）, bilateral Shenmen （神门 HT 7）, bilateral Taichong （太冲 LR 3）, bilateral Neiguan （内关 PC 6） and SanyTnjiao （三阴交 SP 6）. The needles were retained for 30 min. Acupuncture treatment was given once every two days, three treatments a week. The brainstem auditory evoked potential （BAEP） and visual evoked potential （VEP） were observed in 6 weeks of treatment. The change in Hamilton depression scale （HAMD） score was observed before and after treatment in the depression group. Results After treatment, VEP wave latency was shortened significantly in patients of depression （P〈0.05）, BAEPIII wave latency was shortened significantly （P〈0.05）. The score of HAMD was decreased apparently in the depression group （P〈0.05）. Conclusions The stressability of visual and auditory stimuli in the central nervous system was decreased in the patients of depression. Acupuncture shortens remarkably the brainstem evoked potentials latency in the patients of depression and achieves the effective results in the treatment of primary depression.

儿童危重症手足口病43例临床特点分析

目的探讨危重症手足口病患儿的临床特点。方法回顾分析43例危重症手足口病患儿的临床症状、体征、血常规、血生化、胸片、心电图、头颅MR I或CT、EEG、BAEP检查的结果及治疗效果。结果危重症手足口病临床特征:患儿年龄多在3岁以下,发热以高热为主;最常出现的神经系统表现有肢体震颤、精神差、烦躁、惊跳;还可出现血糖升高、肺水肿、肺出血等;脑干听觉诱发电位检查和头颅MR I检查可表现异常;除常规治疗外,40例需行气管插管呼吸机机械通气,38例治愈或好转出院,随访1年,未发现明显的智力落后、继发性癫痫及肢体瘫痪。4例死亡,1例家人放弃治疗,撤离呼吸机机械通气后死亡。结论及早识别危重症手足口病患儿的高危因素、早期干预治疗是减少后遗症、降低病死率、改善患儿预后的关键。脑干听觉诱发电位可作为筛选脑干是否受损的一种常规检查手段。