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Rock mechanics for design of Brisbane tunnels and implications of recent thinking in relation to rock mass strength 被引量:2
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作者 L.B.McQueen A.Purwodihardjo S.V.L.Barrett 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2019年第3期676-683,共8页
This paper explores the potential implications of recent thinking in relation to rock mass strength for future tunnelling projects in Brisbane,Australia,particularly as they are constructed within deep horizons where ... This paper explores the potential implications of recent thinking in relation to rock mass strength for future tunnelling projects in Brisbane,Australia,particularly as they are constructed within deep horizons where the in situ stress magnitudes is larger.Rock mass failure mechanisms for the current tunnels in Brisbane are generally discontinuity controlled and the potential for stress-induced failure is relatively rare.For the road tunnels which have been constructed in Brisbane over the last 12 years,the strength of the more massive rock masses for continuum analysis has been estimated by the application of the Hoek-Brown(H-B)failure criterion using the geological strength index(GSI)to determine the H-B parameters mb,s and a.Over the last few years,alternative approaches to estimating rock mass strength for‘massive to moderately jointed hard rock masses’have been proposed by others,which are built on the work completed by E.Hoek and E.T.Brown in this area over their joint careers.This paper explores one of these alternative approaches to estimating rock mass strength for one of the geological units(the Brisbane Tuff),which is often encountered in tunnelling projects in Brisbane.The potential implications of these strength forecasts for future tunnelling projects are discussed along with the additional work which will need to be undertaken to confirm the applicability of such alternative strength criteria for this rock mass. 展开更多
关键词 Rock mass strength Hoek-Brown(H-B)failure criterion Triaxial testing BRITTLE FAILURE brisbane TUFF
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An Important Forum for the Future of the World’s Rivers: The 8th International Riversymposium in Brisbane
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作者 YAO Lufeng 《Journal of Geographical Sciences》 SCIE CSCD 2005年第4期511-512,共2页
The 8th Intemational Riversymposium was held in Brisbane, Australia on 6-9 September 2005. The Intemational Riversymposium is an integral part of Brisbane's annual broadbased cultural event. The Queensland Government... The 8th Intemational Riversymposium was held in Brisbane, Australia on 6-9 September 2005. The Intemational Riversymposium is an integral part of Brisbane's annual broadbased cultural event. The Queensland Government is a foundation partner of the Intemational River Foundation, formed to secure the future of the Intemational and National Thiess Riverprize. The theme of symposium in this year is “Water and Food Security- Rivers in a Global Context” ( www.riversymposium.com ). The Riversymposium provides a global forum which aims to make a difference to the declining state of rivers and waterways globally. Its strength lies in the breadth of its challenging program content of important keynote presentations and case studies of rivers in crisis, attracting a diverse range of national and intemational delegates. Some 450 scientists from 38 countries attended this conference, and about 100 papers were presented on the symposium in 2005. 展开更多
关键词 An Important Forum for the Future of the World The 8th International Riversymposium in brisbane s Rivers
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IGU-2006 Brisbane Conference Convened in Brisbane, Australia
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作者 ZHAO Xin 《Journal of Geographical Sciences》 SCIE CSCD 2006年第4期509-509,共1页
The IGU-2006 Brisbane Conference was convened on 3-7 July 2006 in Queenland University of Technology, Brisbane, Australia. Approximately 1000 geographers from nearly 50 countries and regions participated in the IGU-20... The IGU-2006 Brisbane Conference was convened on 3-7 July 2006 in Queenland University of Technology, Brisbane, Australia. Approximately 1000 geographers from nearly 50 countries and regions participated in the IGU-2006 Brisbane Conference, which was sponsored by International Geographical Union (IGU), and organized by the Institute of Australian Geographers (IAG) and the New Zealand Geographical Society (NZGS). 展开更多
关键词 IGU-2006 brisbane Conference Convened in brisbane AUSTRALIA
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雪貂感染流感病毒H3N2动物模型的建立 被引量:7
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作者 鲍琳琳 占玲俊 +5 位作者 邓巍 许黎黎 朱华 吕琦 李枫棣 秦川 《中国比较医学杂志》 CAS 2011年第8期5-9,F0002,共6页
目的建立甲型流感病毒H3N2感染的雪貂动物模型。方法按实验要求筛选出流感抗体反应阴性的雪貂,经兽用氯胺酮轻度麻醉后进行滴鼻感染H3N2流感病毒株A/Brisbane/10/07,设立两个稀释度106和107 TCID50,每个稀释度接种3只雪貂,感染后第5天... 目的建立甲型流感病毒H3N2感染的雪貂动物模型。方法按实验要求筛选出流感抗体反应阴性的雪貂,经兽用氯胺酮轻度麻醉后进行滴鼻感染H3N2流感病毒株A/Brisbane/10/07,设立两个稀释度106和107 TCID50,每个稀释度接种3只雪貂,感染后第5天安乐处死。感染前采集鼻甲骨活检,感染后1~5 d鼻甲骨活检检测病毒载量,每天记录雪貂一般临床变化。处死时取雪貂肺、肝、脾、小肠、脑组织作病毒滴度检测,肺组织做病理检查。结果 106和107TCID50的H3N2病毒分别感染雪貂,没有雪貂死亡。雪貂感染后都出现一过性的体温升高,体重的下降,流涕、打喷嚏等症状。在鼻甲骨活检物中可测到病毒载量,肠组织可分离到病毒。肺组织以轻度性间质性肺炎为主要病理变化。结论雪貂感染H3N2病毒株A/Brisbane/10/07后,临床表现、病毒学、分子生物学、病理学方面的检测都可以证实雪貂感染H3N2病毒动物模型已建立,其中106 TCID50病毒滴度的是一个建立感染动物模型比较合适的剂量。 展开更多
关键词 A/brisbane/10/07 H3N2 雪貂 模型 动物
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甲型H1N1流感病毒在季流病毒、禽流感病毒共感染时变异可能性的验证
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作者 鲍琳琳 许黎黎 +6 位作者 孙惠惠 占玲俊 邓巍 朱华 高虹 陈鸿霖 秦川 《中国实验动物学报》 CAS CSCD 2011年第3期211-215,共5页
目的甲型H1N1流感病毒A/California/7/2009分别与A/Brisbane/10/07和A/ShenZhen/406H/06共感染小型香猪,预测甲流病毒在与季流H3N2病毒/甲流病毒与禽流感病毒共感染时是否会发生变异。方法分别将A/California/7/2009(CA7)与A/Brisbane/1... 目的甲型H1N1流感病毒A/California/7/2009分别与A/Brisbane/10/07和A/ShenZhen/406H/06共感染小型香猪,预测甲流病毒在与季流H3N2病毒/甲流病毒与禽流感病毒共感染时是否会发生变异。方法分别将A/California/7/2009(CA7)与A/Brisbane/10/07(H3N2),A/California/7/2009与A/Shenzhen/406H/06(H5N1)对5~6月龄小型猪共感染,小型猪经复方氯胺酮0.1 mL/kg麻醉后进行滴鼻感染,感染后第5天安乐死动物,取动物肺组织作病毒测序分析。结果 A/California/7/2009(CA7)与A/Brisbane/10/07(H3N2)共感染后,A/California/7/2009病毒PB1基因993位G→A突变,PA基因1659位G→A突变,没有氨基酸的变异。A/California/7/2009与A/Shenzhen/406H/06(H5N1)共感染后A/California/7/2009病毒PB2基因1711位T→C突变。碱基的突变未引起氨基酸的变异。结论 A/California/7/2009(CA7)与A/Brisbane/10/07(H3N2),A/California/7/2009与A/Shenzhen/406H/06(H5N1)共感染后在猪的体内没有发生病毒重组、变异。 展开更多
关键词 A/California/7/2009 A/brisbane/10/07 A/Shenzhen/406H/06 小型猪 变异
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