A self-developed laser image measurement system was established to study the behavior of bubble for- mation at a single orifice in non-Newtonian polyacrylamide(PAAm)solutions.Images of bubbles were captured by a CCD c...A self-developed laser image measurement system was established to study the behavior of bubble for- mation at a single orifice in non-Newtonian polyacrylamide(PAAm)solutions.Images of bubbles were captured by a CCD camera and volumes of bubbles were digitally analyzed online.The effects of rheological property of PAAm solution,orifice,reservoir,and gas flowrate on bubble formation were studied experimentally.It is found that the volume of bubble increases with the concentration of PAAm solution,the diameter of the orifice,and the gas flowrate,respectively,whereas little effect of reservoir is observed in experiments.展开更多
Based on the comprehensive forces balance model, a modified model of the formation of a single bub-ble in non-Newtonian fluid under constant flowrate was developed by taking account of the effect of the ingoing gas th...Based on the comprehensive forces balance model, a modified model of the formation of a single bub-ble in non-Newtonian fluid under constant flowrate was developed by taking account of the effect of the ingoing gas through orifice as well as its variation on the radial expansion of bubble. The modified model involves the radial expansion equation of bubble surface and the forces balance equation in vertical direction of the bubble respec-tively. The shape variation of bubbles formed in polyacrylamide (PAM) aqueous solutions under various conditions was predicted numerically. The practical formation of bubbles was real-time visualized and recorded by a CCD camera and a computer by means of a special laser image measurement system. Results show that the predicted shapes of the bubbles by the present model agree well with experimental observation.展开更多
Bubble formation in an opposite-flowing T-shaped microchannel with 40 μm in depth and 120 μm in width was real-time visualized and investigated experimentally by means of a high speed camera. N2 bubbles were generat...Bubble formation in an opposite-flowing T-shaped microchannel with 40 μm in depth and 120 μm in width was real-time visualized and investigated experimentally by means of a high speed camera. N2 bubbles were generated in glycerol-water mixtures with different concentrations of surfactant sodium dodecyl sulfate (SDS). And the images were captured by the high speed camera linked to a computer. Results indicated that the bubble formation process can be distinguished into three consecutive stages, i.e., expansion, collapse and pinching off. The bubble size decreases with the increase of liquid flow rate and viscosity of liquid phase as well as the decrease of gas flow rate. The surface tension of the liquid phase has no measurable influence on the bubble size. Moreover, a new approach to predicting the size of bubbles formed in the T-shaped microchannel is proposed. And the predicted values agree well with the experimental data.展开更多
The bubble formation process at submerged orifices with different geometry is investigated in the preparation of aluminum foams by gas injection method.The bubble profile on a horizontal plate is calculated by quasi-s...The bubble formation process at submerged orifices with different geometry is investigated in the preparation of aluminum foams by gas injection method.The bubble profile on a horizontal plate is calculated by quasi-static analysis through Laplace equation.The bubble formation process is then distinguished into three stages:nucleation stage,growth stage and detachment stage in wetting and less wetting conditions based on the force balance analysis.In addition,the bubble size at high Reynolds number is obtained by considering the contribution of buoyancy,pressure force,inertial force,drag force and surface tension based on the three stages of bubble formation.The bubble size is confirmed to be sensitive to the equivalent contact angle,which consists of two terms including the contact angle and the wedge angle.Therefore,the wedge angle is introduced in the design of gas outlet orifices for the purpose of decreasing bubble size generated.The experimental study is conducted at three different types of stainless steel orifices under constant gas flow rates(0.05–2 L/min).It is clarified that the orifice geometry and the orifice size are both responsible for the cell size of aluminum foams.The experimental results for three different types of orifices show a consistent trend with the theoretical predictions at various gas flow rates.In the design of orifices to generate small bubbles in the melt,the wedge angle that coordinates with the contact angle is thus suggested.展开更多
We investigated the environment of the infrared dust bubble N68 and searched for evidence of triggered star formation in its surroundings. We performed a multiwavelength study of the nebula with data taken from severa...We investigated the environment of the infrared dust bubble N68 and searched for evidence of triggered star formation in its surroundings. We performed a multiwavelength study of the nebula with data taken from several large-scale surveys: GLIMPSE, MIPSGAL, IRAS, NVSS, GRS and JCMT. We analyzed the spectral pro- file and the distribution of the molecular gas (13CO J -- 1 - 0 and J -- 3 - 2), and the dust in the environment of N68. The position-velocity diagram clearly shows that N68 may be expanding outward. We used two three-color images of the mid-infrared emis- sion to explore the physical environment, and one color-color diagram to investigate the distribution of young stellar objects (YSOs). We found that the 24 p^m emission is surrounded by the 8.0 ~m emission. Morphologically, the 1.4 GHz continuum strongly correlates with the 24 gm emission, and the 13CO J -- 1 - 0 and J -- 3 - 2 emissions correlate well with the 8.0 p^m emission. We investigated two compact cores located in the shell of N68. The spectral intensity ratios of 13CO J -- 3 - 2 to J = 1 - 0 range from 5 to 0.3. In addition, YSOs, masers, IRAS and UC HII regions are distributed in the shell of the bubble. The active region may be triggered by the expansion of the bubble N68.展开更多
The size of initial bubbles is an important factor to the developed bubble size distribution in a gas-liquid contactor. A liquid cross-flow over a sparger can produce smaller bubbles, and hereby enhance the performanc...The size of initial bubbles is an important factor to the developed bubble size distribution in a gas-liquid contactor. A liquid cross-flow over a sparger can produce smaller bubbles, and hereby enhance the performance of contactor. A one stage model by balancing the forces acting on a growing bubble was developed to describe the formation of the bubble from an orifice exposed to liquid cross-flow. The prediction with this model agrees with the experimental data available in the literatures, and show that orifice size strongly affects the bubble size. It is showed that the shear-lift force, inertia force, surface tension force and buoyancy force are major forces, and a simplified mathematical model was developed, and the detachment bubble diameter can be predicted with accuracy of <±21%.展开更多
We investigate 25 H II regions that show bubble morphology in 13CO(1-0) and infrared data, to search for quantitative evidence of triggered star formation by processes described by the collect and collapse (CC) an...We investigate 25 H II regions that show bubble morphology in 13CO(1-0) and infrared data, to search for quantitative evidence of triggered star formation by processes described by the collect and collapse (CC) and radiatively driven implosion (RDI) models. These H II regions display the morphology of a complete or partial bubble at 8 μm, and are all associated with the molecular clouds that surround them. We found that the electron temperature ranges from 5627 K to 6839 K in these H II regions, and the average electron temperature is 6083 K. The age of these H II regions is from 3.0× 10^5 yr to 1.7 × 10^6 yr, and the mean age is 7.7 × 10^5 yr. Based on the mor- phology of the associated molecular clouds, we divide these H II regions into three groups, which may support CC and RDI models. We select 23 young IRAS sources which have an infrared luminosity of 〉 10^3 Lo in 19 H II regions. In addition, we iden- tify some young stellar objects (including Class I sources), which are only concen- trated in H II regions G29.007+0.076, G44.339-0.827 and G47.028+0.232. The poly- cyclic aromatic hydrocarbon emissions of the three H II regions all show a cometary globule. Comparing the age of each H II region with the characteristic timescales for star formation, we suggest that the three H II regions can trigger clustered star forma- tion by an RDI process. In addition, we detect seven molecular outflows in the five H II regions for the first time. These outflow sources may be triggered by the corresponding H II regions.展开更多
We present a study of the Galactic bubble N4 using the 13.7 m millimeterwave telescope, which is managed by Purple Mountain Observatory at Qinghai Station. N4 is one of the science demonstration regions where simultan...We present a study of the Galactic bubble N4 using the 13.7 m millimeterwave telescope, which is managed by Purple Mountain Observatory at Qinghai Station. N4 is one of the science demonstration regions where simultaneous observations of ^12CO (J = 1 - 0), ^13CO (J = 1 - 0) and C^18O (J = 1 - 0) line emission towards N4 were carried out under the project Milky Way Imaging Scroll Painting (MWISP). We analyze the spectral profile and the distribution of the molecular gas. Morphologically, the CO emissions correlate well with Spitzer IRAC 8.0 p-m emission. The channel map and velocity-position diagram show that N4 is more likely to be an inclined expanding ring rather than a spherical bubble. We calculated the physical parameters of N4 including mass, size, column density and optical depth. Some massive star candidates were discovered in the region of N4 using the (J, J-H) colormagnitude diagram. We found a candidate for the energy source driving the expansion of N4, a massive star with a mass of -15 M⊙ and an age of - 1Myr. There is the signature of infall motion in N4, which can be a good candidate for the infall area. Combining millimeter and infrared data, we suggest that triggered star formation can exist in N4.展开更多
Objective: Laser-induced Coulomb explosion of gold nanoparticles for breast cancer has been studied by nanophotolysis technique. This study aimed to investigate whether laser-induced bubble formation due to Coulomb e...Objective: Laser-induced Coulomb explosion of gold nanoparticles for breast cancer has been studied by nanophotolysis technique. This study aimed to investigate whether laser-induced bubble formation due to Coulomb explosion can provide an effective approach for selective damage of breast cancer with gold nanoparticles. Method: Numerical method involves laser-induced Coulomb explosion of gold nanoparticles. Different parameters related to nanophotolysis such as laser fluence, tumor depth, cluster radius, laser pulse duration, and bubble formation is studied numerically. Numerical simulation was performed using Mat lab. Results: The gold nanopartieles of 10, 20, 30, 40, and 50 nm in radius could penetrate into tumor 1.14, 1.155, 1.189, 1.20 and 1.22 cm in depth respectively. The maximum penetration depth in tumor could be obtained with nanoparticles of 50 nm radius. Short laser pulse of 40 ns with nanoparticles of 10 nm radius could penetrate into tumor 1.14 cm in depth. Bubbles with a radius of 9 pm could effectively kill breast cancer cells without damaging healthy ones. The bubble radius increased from 4 to 9 lam with an increase in pulse duration in the range of 10 to 30 ns. Conclusions: Gold nanoparticles with increasing radius and bubble formation for selective damage of breast cancer cells are successfully probed. The present calculated results are compared with other experimental findings, and good correlation is found between the present work and previous experimental values. It was demonstrated that bubble formation in tumor may further increase the efficacy of breast cancer treatment.展开更多
Foam trays with porous submerged orifices endow bubbles uniformly distributed,which are considered attractive column internals to enhance the gas-liquid mass transfer process.However,its irregular orifice and complex ...Foam trays with porous submerged orifices endow bubbles uniformly distributed,which are considered attractive column internals to enhance the gas-liquid mass transfer process.However,its irregular orifice and complex gas-liquid flow make it lack pore-scale investigations concerning the transfer mechanism of dynamic bubbling.In this work,the actual porous structure of the foam tray is obtained based on micro computed tomography technology.The shape,dynamic,and mass transfer of rising bubbles at porous orifices are investigated using the volume of fluid and continue surface force model.The results demonstrate that the liquid encroaching on the gas channels causes the increasing orifices velocity,which makes the trailing bubble easily detach from the midst of the leading bubble and causes pairing coalescence.Additionally,we found that the central breakup regimes significantly improve the gas-liquid interface area and mass transfer efficiency.This discovery exemplifies the mechanism of mass transfer intensification for foam trays and serves to promote its further development.展开更多
The shape evolution of bubble formed in carboxymethylcellulose(CMC) aqueous solution was real-time observed using laser image technique. The flow fields of liquid around growing and rising bubble were measured by lase...The shape evolution of bubble formed in carboxymethylcellulose(CMC) aqueous solution was real-time observed using laser image technique. The flow fields of liquid around growing and rising bubble were measured by laser Doppler velocimetry(LDV), and the liquid mean velocity and its contour curves were obtained. The results show that bubble grows as spherical shape because of the dominant role of surface tension in the early period, and then is stretched gradually as a teardrop shape due to the common effect of buoyancy and shear-thinning of fluid. The axial mean velocity of liquid phase takes on Gaussian distribution with the symmetrical axis passing through orifice center. However, the radial mean velocity increases first and then decreases with the increase of the distance from measured point to the symmetrical axis above. Further, the axial component along symmetrical axis decreases initially and increases with the rise of height, as well as its corresponding contour map diverging gradually. The radial component, yet, decreases steadily with the rise of height, and the maximum value deviates towards the two sides until disappear, as it contour shape of butterfly's "front wing".展开更多
An analytical solution is derived with the mirror image method of the velocity field of an inviscid liquid induced by a growing bubble from a plate orifice. The flow is assumed potential, and the bubble shape is ideal...An analytical solution is derived with the mirror image method of the velocity field of an inviscid liquid induced by a growing bubble from a plate orifice. The flow is assumed potential, and the bubble shape is idealised as spherical. In deriving the motion equation, the spherical image of a point source, which is a combination of a point source and a line source, is proved approximate to a double source. This approximation enables continuation of the effectiveness of mirror image method to the case studied in this paper. The derived velocity potential equation is verified for the boundary conditions on the bubble surface and the orifice plate. The streamlines of the velocity field are presented and compared with experimental results in the literature.展开更多
The present paper describes the nonlinear behavior of bubble formation from a single submerged orifice and induced liquid motion (micro convection) surrounding the bubble. The experimental data reveals that depart...The present paper describes the nonlinear behavior of bubble formation from a single submerged orifice and induced liquid motion (micro convection) surrounding the bubble. The experimental data reveals that departing periods of successive bubbles evolve multiple periods from single to triple periods when the gas flow rate is increased and that the micro convection evolves bifurcation phenomena similar to the so called 'period doubling' in chaos dynamics. The photographic observation using high speed video movies and data analysis indicate that the nonlinear features come from the deformation of the bubble and also the interaction between consecutive bubbles. A new comprehensive theoretical model is developed for describing the instantaneous bubble behaviors during formation and ascendance processes and for predicting the departing periods and sizes of successive bubbles for constant flow rate conditions. Owing to the estimation of instantaneous interactions between successive bubbles and the incorporation of the wake effect of previous bubbles, the present model describes the evolution process and mechanisms of bubble departing periods corresponding to different gas flow rate regimes. The theoretical results are in good agreement with experimental results.展开更多
Numerical and experimental study is carried to investigate the cavitation behavior in the turbulent flow around a NACA16-012 hydrofoil. The Navier-Stokes Equations for compressible fluid are adopted to simulate the ov...Numerical and experimental study is carried to investigate the cavitation behavior in the turbulent flow around a NACA16-012 hydrofoil. The Navier-Stokes Equations for compressible fluid are adopted to simulate the overall motion and dynamical characteristics of the cavity flow, while the bubble dynamics is used to calculate the motion and growth of nuclei inside the cavity. Cavitation experiment for the hydrofoil is carried out in a water tunnel of CSS-RC, the phenomenon in the experiment is recorded and analyzed with high speed photographic technique.展开更多
In the restricted flow region of a pipe, cavitation will occur. In order to predict the cavitation occurence, the pressure distribution of the throat region should first be estimated. This paper presented a method for...In the restricted flow region of a pipe, cavitation will occur. In order to predict the cavitation occurence, the pressure distribution of the throat region should first be estimated. This paper presented a method for predicting cavitation inception in pipe. The mathematic model was proposed and the fluctuating pressure in the flow and other random factors with respect to gas nuclei were treated using the Monte-Carlo method. So that the bridge between macroscopic aspect of the cavitation in the flow and microscopic event of individual nucleus cavitation was set up. Numerical investigation and experimental test were carried out for the flow through an orifice in an uniform pipe with circular section. The approximate method presented in this paper can be adopted to engineering design of corresponding pipelines展开更多
基金Supported by the National Natural Science Foundation of China (No.20476073) and the Programs of Introducing Talents of Discipline to Universities (Grant No.B06006).
文摘A self-developed laser image measurement system was established to study the behavior of bubble for- mation at a single orifice in non-Newtonian polyacrylamide(PAAm)solutions.Images of bubbles were captured by a CCD camera and volumes of bubbles were digitally analyzed online.The effects of rheological property of PAAm solution,orifice,reservoir,and gas flowrate on bubble formation were studied experimentally.It is found that the volume of bubble increases with the concentration of PAAm solution,the diameter of the orifice,and the gas flowrate,respectively,whereas little effect of reservoir is observed in experiments.
基金Supported by National Natural Science Foundation of China (No.20476073)National Programme of Introducing Talents of Discipline to Universities (No.B06006).
文摘Based on the comprehensive forces balance model, a modified model of the formation of a single bub-ble in non-Newtonian fluid under constant flowrate was developed by taking account of the effect of the ingoing gas through orifice as well as its variation on the radial expansion of bubble. The modified model involves the radial expansion equation of bubble surface and the forces balance equation in vertical direction of the bubble respec-tively. The shape variation of bubbles formed in polyacrylamide (PAM) aqueous solutions under various conditions was predicted numerically. The practical formation of bubbles was real-time visualized and recorded by a CCD camera and a computer by means of a special laser image measurement system. Results show that the predicted shapes of the bubbles by the present model agree well with experimental observation.
基金Supported by National Natural Science Foundation of China (No. 20876107)Open Project of State Key Laboratory of Chemical Engineering (No. SKL-ChE-08B06) Program of Introducing Talents of Discipline to Universities (No. B06006)
文摘Bubble formation in an opposite-flowing T-shaped microchannel with 40 μm in depth and 120 μm in width was real-time visualized and investigated experimentally by means of a high speed camera. N2 bubbles were generated in glycerol-water mixtures with different concentrations of surfactant sodium dodecyl sulfate (SDS). And the images were captured by the high speed camera linked to a computer. Results indicated that the bubble formation process can be distinguished into three consecutive stages, i.e., expansion, collapse and pinching off. The bubble size decreases with the increase of liquid flow rate and viscosity of liquid phase as well as the decrease of gas flow rate. The surface tension of the liquid phase has no measurable influence on the bubble size. Moreover, a new approach to predicting the size of bubbles formed in the T-shaped microchannel is proposed. And the predicted values agree well with the experimental data.
基金supported by the International Cooperation Project of Ministry of Science and Technology of China(Grant No.2013DFR50330)
文摘The bubble formation process at submerged orifices with different geometry is investigated in the preparation of aluminum foams by gas injection method.The bubble profile on a horizontal plate is calculated by quasi-static analysis through Laplace equation.The bubble formation process is then distinguished into three stages:nucleation stage,growth stage and detachment stage in wetting and less wetting conditions based on the force balance analysis.In addition,the bubble size at high Reynolds number is obtained by considering the contribution of buoyancy,pressure force,inertial force,drag force and surface tension based on the three stages of bubble formation.The bubble size is confirmed to be sensitive to the equivalent contact angle,which consists of two terms including the contact angle and the wedge angle.Therefore,the wedge angle is introduced in the design of gas outlet orifices for the purpose of decreasing bubble size generated.The experimental study is conducted at three different types of stainless steel orifices under constant gas flow rates(0.05–2 L/min).It is clarified that the orifice geometry and the orifice size are both responsible for the cell size of aluminum foams.The experimental results for three different types of orifices show a consistent trend with the theoretical predictions at various gas flow rates.In the design of orifices to generate small bubbles in the melt,the wedge angle that coordinates with the contact angle is thus suggested.
基金supported by the Young Researcher Grant of the National Astronomical Observatories,Chinese Academy of Sciences (Grant No. O835032002)
文摘We investigated the environment of the infrared dust bubble N68 and searched for evidence of triggered star formation in its surroundings. We performed a multiwavelength study of the nebula with data taken from several large-scale surveys: GLIMPSE, MIPSGAL, IRAS, NVSS, GRS and JCMT. We analyzed the spectral pro- file and the distribution of the molecular gas (13CO J -- 1 - 0 and J -- 3 - 2), and the dust in the environment of N68. The position-velocity diagram clearly shows that N68 may be expanding outward. We used two three-color images of the mid-infrared emis- sion to explore the physical environment, and one color-color diagram to investigate the distribution of young stellar objects (YSOs). We found that the 24 p^m emission is surrounded by the 8.0 ~m emission. Morphologically, the 1.4 GHz continuum strongly correlates with the 24 gm emission, and the 13CO J -- 1 - 0 and J -- 3 - 2 emissions correlate well with the 8.0 p^m emission. We investigated two compact cores located in the shell of N68. The spectral intensity ratios of 13CO J -- 3 - 2 to J = 1 - 0 range from 5 to 0.3. In addition, YSOs, masers, IRAS and UC HII regions are distributed in the shell of the bubble. The active region may be triggered by the expansion of the bubble N68.
基金Supported by the National Natural Science Foundation of China (20736009)
文摘The size of initial bubbles is an important factor to the developed bubble size distribution in a gas-liquid contactor. A liquid cross-flow over a sparger can produce smaller bubbles, and hereby enhance the performance of contactor. A one stage model by balancing the forces acting on a growing bubble was developed to describe the formation of the bubble from an orifice exposed to liquid cross-flow. The prediction with this model agrees with the experimental data available in the literatures, and show that orifice size strongly affects the bubble size. It is showed that the shear-lift force, inertia force, surface tension force and buoyancy force are major forces, and a simplified mathematical model was developed, and the detachment bubble diameter can be predicted with accuracy of <±21%.
基金Supported by the National Natural Science Foundation of China
文摘We investigate 25 H II regions that show bubble morphology in 13CO(1-0) and infrared data, to search for quantitative evidence of triggered star formation by processes described by the collect and collapse (CC) and radiatively driven implosion (RDI) models. These H II regions display the morphology of a complete or partial bubble at 8 μm, and are all associated with the molecular clouds that surround them. We found that the electron temperature ranges from 5627 K to 6839 K in these H II regions, and the average electron temperature is 6083 K. The age of these H II regions is from 3.0× 10^5 yr to 1.7 × 10^6 yr, and the mean age is 7.7 × 10^5 yr. Based on the mor- phology of the associated molecular clouds, we divide these H II regions into three groups, which may support CC and RDI models. We select 23 young IRAS sources which have an infrared luminosity of 〉 10^3 Lo in 19 H II regions. In addition, we iden- tify some young stellar objects (including Class I sources), which are only concen- trated in H II regions G29.007+0.076, G44.339-0.827 and G47.028+0.232. The poly- cyclic aromatic hydrocarbon emissions of the three H II regions all show a cometary globule. Comparing the age of each H II region with the characteristic timescales for star formation, we suggest that the three H II regions can trigger clustered star forma- tion by an RDI process. In addition, we detect seven molecular outflows in the five H II regions for the first time. These outflow sources may be triggered by the corresponding H II regions.
基金funded by the National Aeronautics and Space Administrationthe National Science Foundation+1 种基金supported by the National Natural Science Foundation of China (Grant Nos. 10873037, 10921063 and 11233007)supported by the National Basic Research Program of China (973 program, 2007CB815406)
文摘We present a study of the Galactic bubble N4 using the 13.7 m millimeterwave telescope, which is managed by Purple Mountain Observatory at Qinghai Station. N4 is one of the science demonstration regions where simultaneous observations of ^12CO (J = 1 - 0), ^13CO (J = 1 - 0) and C^18O (J = 1 - 0) line emission towards N4 were carried out under the project Milky Way Imaging Scroll Painting (MWISP). We analyze the spectral profile and the distribution of the molecular gas. Morphologically, the CO emissions correlate well with Spitzer IRAC 8.0 p-m emission. The channel map and velocity-position diagram show that N4 is more likely to be an inclined expanding ring rather than a spherical bubble. We calculated the physical parameters of N4 including mass, size, column density and optical depth. Some massive star candidates were discovered in the region of N4 using the (J, J-H) colormagnitude diagram. We found a candidate for the energy source driving the expansion of N4, a massive star with a mass of -15 M⊙ and an age of - 1Myr. There is the signature of infall motion in N4, which can be a good candidate for the infall area. Combining millimeter and infrared data, we suggest that triggered star formation can exist in N4.
基金financial support by by Fund of the Ministry of Higher Education(MOHE)Malaysia and Universiti Teknologi Malaysia(UTM)Skudai,Johor,Malaysia under Grant No Q.J130000.2526.02H93/-03H78
文摘Objective: Laser-induced Coulomb explosion of gold nanoparticles for breast cancer has been studied by nanophotolysis technique. This study aimed to investigate whether laser-induced bubble formation due to Coulomb explosion can provide an effective approach for selective damage of breast cancer with gold nanoparticles. Method: Numerical method involves laser-induced Coulomb explosion of gold nanoparticles. Different parameters related to nanophotolysis such as laser fluence, tumor depth, cluster radius, laser pulse duration, and bubble formation is studied numerically. Numerical simulation was performed using Mat lab. Results: The gold nanopartieles of 10, 20, 30, 40, and 50 nm in radius could penetrate into tumor 1.14, 1.155, 1.189, 1.20 and 1.22 cm in depth respectively. The maximum penetration depth in tumor could be obtained with nanoparticles of 50 nm radius. Short laser pulse of 40 ns with nanoparticles of 10 nm radius could penetrate into tumor 1.14 cm in depth. Bubbles with a radius of 9 pm could effectively kill breast cancer cells without damaging healthy ones. The bubble radius increased from 4 to 9 lam with an increase in pulse duration in the range of 10 to 30 ns. Conclusions: Gold nanoparticles with increasing radius and bubble formation for selective damage of breast cancer cells are successfully probed. The present calculated results are compared with other experimental findings, and good correlation is found between the present work and previous experimental values. It was demonstrated that bubble formation in tumor may further increase the efficacy of breast cancer treatment.
基金grateful for the financial support from the National Natural Science Foundation of China(Grant No.22178249).
文摘Foam trays with porous submerged orifices endow bubbles uniformly distributed,which are considered attractive column internals to enhance the gas-liquid mass transfer process.However,its irregular orifice and complex gas-liquid flow make it lack pore-scale investigations concerning the transfer mechanism of dynamic bubbling.In this work,the actual porous structure of the foam tray is obtained based on micro computed tomography technology.The shape,dynamic,and mass transfer of rising bubbles at porous orifices are investigated using the volume of fluid and continue surface force model.The results demonstrate that the liquid encroaching on the gas channels causes the increasing orifices velocity,which makes the trailing bubble easily detach from the midst of the leading bubble and causes pairing coalescence.Additionally,we found that the central breakup regimes significantly improve the gas-liquid interface area and mass transfer efficiency.This discovery exemplifies the mechanism of mass transfer intensification for foam trays and serves to promote its further development.
基金Financially supported by National Natural Science Foundation of China(21076139,21106106)Tianjin Natural Science Foundation(12JCQNJC03700)Foundation of Tianjin Educational Committee of China(20100508)
文摘The shape evolution of bubble formed in carboxymethylcellulose(CMC) aqueous solution was real-time observed using laser image technique. The flow fields of liquid around growing and rising bubble were measured by laser Doppler velocimetry(LDV), and the liquid mean velocity and its contour curves were obtained. The results show that bubble grows as spherical shape because of the dominant role of surface tension in the early period, and then is stretched gradually as a teardrop shape due to the common effect of buoyancy and shear-thinning of fluid. The axial mean velocity of liquid phase takes on Gaussian distribution with the symmetrical axis passing through orifice center. However, the radial mean velocity increases first and then decreases with the increase of the distance from measured point to the symmetrical axis above. Further, the axial component along symmetrical axis decreases initially and increases with the rise of height, as well as its corresponding contour map diverging gradually. The radial component, yet, decreases steadily with the rise of height, and the maximum value deviates towards the two sides until disappear, as it contour shape of butterfly's "front wing".
文摘An analytical solution is derived with the mirror image method of the velocity field of an inviscid liquid induced by a growing bubble from a plate orifice. The flow is assumed potential, and the bubble shape is idealised as spherical. In deriving the motion equation, the spherical image of a point source, which is a combination of a point source and a line source, is proved approximate to a double source. This approximation enables continuation of the effectiveness of mirror image method to the case studied in this paper. The derived velocity potential equation is verified for the boundary conditions on the bubble surface and the orifice plate. The streamlines of the velocity field are presented and compared with experimental results in the literature.
文摘The present paper describes the nonlinear behavior of bubble formation from a single submerged orifice and induced liquid motion (micro convection) surrounding the bubble. The experimental data reveals that departing periods of successive bubbles evolve multiple periods from single to triple periods when the gas flow rate is increased and that the micro convection evolves bifurcation phenomena similar to the so called 'period doubling' in chaos dynamics. The photographic observation using high speed video movies and data analysis indicate that the nonlinear features come from the deformation of the bubble and also the interaction between consecutive bubbles. A new comprehensive theoretical model is developed for describing the instantaneous bubble behaviors during formation and ascendance processes and for predicting the departing periods and sizes of successive bubbles for constant flow rate conditions. Owing to the estimation of instantaneous interactions between successive bubbles and the incorporation of the wake effect of previous bubbles, the present model describes the evolution process and mechanisms of bubble departing periods corresponding to different gas flow rate regimes. The theoretical results are in good agreement with experimental results.
基金This work is supported by the National Natural Science Foundation of China under the grant number 58909464
文摘Numerical and experimental study is carried to investigate the cavitation behavior in the turbulent flow around a NACA16-012 hydrofoil. The Navier-Stokes Equations for compressible fluid are adopted to simulate the overall motion and dynamical characteristics of the cavity flow, while the bubble dynamics is used to calculate the motion and growth of nuclei inside the cavity. Cavitation experiment for the hydrofoil is carried out in a water tunnel of CSS-RC, the phenomenon in the experiment is recorded and analyzed with high speed photographic technique.
基金The Present work is supported by the National Natural Science Foundation of China under the grant number 58909464.
文摘In the restricted flow region of a pipe, cavitation will occur. In order to predict the cavitation occurence, the pressure distribution of the throat region should first be estimated. This paper presented a method for predicting cavitation inception in pipe. The mathematic model was proposed and the fluctuating pressure in the flow and other random factors with respect to gas nuclei were treated using the Monte-Carlo method. So that the bridge between macroscopic aspect of the cavitation in the flow and microscopic event of individual nucleus cavitation was set up. Numerical investigation and experimental test were carried out for the flow through an orifice in an uniform pipe with circular section. The approximate method presented in this paper can be adopted to engineering design of corresponding pipelines