Two new C21 steroidal glycosides, cynanauriculoside I and cynanauriculoside II, were isolated from the roots of Cynanchum aurichulatum. Their structures were established using spectroscopic methods including one and ...Two new C21 steroidal glycosides, cynanauriculoside I and cynanauriculoside II, were isolated from the roots of Cynanchum aurichulatum. Their structures were established using spectroscopic methods including one and two-dimensional NMR.展开更多
A new C21 steroidal glycoside, named cynanversicoside F （1）, was isolated from the root of Cynanchum versicolor Bunge. Its structure was established as glaucogenin-A 3-O-β-D- digitoxopyranosyl-（1→4）-β-D-cymarop...A new C21 steroidal glycoside, named cynanversicoside F （1）, was isolated from the root of Cynanchum versicolor Bunge. Its structure was established as glaucogenin-A 3-O-β-D- digitoxopyranosyl-（1→4）-β-D-cymaropyranoside by spectroscopic and chemical methods.展开更多
Objective To investigate the chemical structures of glycosides in the roots of Cynanchum otophyllum（Asclepiadaceae） and to find new glycosides. Methods The total glycosides in the roots of C. olophyllum were separat...Objective To investigate the chemical structures of glycosides in the roots of Cynanchum otophyllum（Asclepiadaceae） and to find new glycosides. Methods The total glycosides in the roots of C. olophyllum were separated by silica gel column chromatography. The structures of the resulting compounds were determined by NMR and FAB-MS spectra. Results Three C21 steroidal glycosides were separated. Their structures were determined as caudatin 3-O-（4-O-methyl-β-D-cymaropyranosyl）-（1→4）-ɑ-D-oleandropyranosyl-（1→4）-β-D-glucopyranosyl-（1→4）-ɑ-L-rhamnopyranoside（1）, caudatin 3-O-β-D-digitoxopyranosyl-（1→4）-ɑ-D-oleandropyranosyl-（1→4）-β-Ddiginopyranosyl-（1→4）-β-D-glucopyranoside（2）, and caudatin 3-O-β-D-diginopyranosyl-（1→4）-ɑ-D-oleandropyranosyl-（1→4）-ɑ-D-oleandropyranosyl-（1→4）-β-Dglucopyranoside（3）, respectively. Conclusion Glycosides 1-3 are new compounds.展开更多
Objective To investigate the structures of compounds in the rhizome of Cynanchum otophyllum（Asclepiadaceae）, and to find new C21 steroidal glycosides. Methods The ethyl acetate extract from the rhizome was subjected...Objective To investigate the structures of compounds in the rhizome of Cynanchum otophyllum（Asclepiadaceae）, and to find new C21 steroidal glycosides. Methods The ethyl acetate extract from the rhizome was subjected to acidic hydrolysis and isolated by column chromatography; The structures of the purified compounds were determined by spectral methods. Literature search confirmed whether those compounds were of new structures. Results Three compounds were isolated and their structures were deacetylmetaplexigenin 3-O-β-D-oleandropyranosyl-（1→4）-α-D-oleandropyranosyl-（1→4）-α-D-oleandropyranoside（1）, deacetylmetaplexigenin 3-O-α-D-oleandropyranosyl-（1→4）-β-D-thevetopyranosyl-（1→4）-α-D-oleandropyranoside（2）, and deacetylmeta-plexigenin 3-O-β-D-cymaropyranosyl-（1→4）-α-D-oleandropyranoside（3）, respectively. Conclusion Compounds 1-3 are new compounds.展开更多
文摘Two new C21 steroidal glycosides, cynanauriculoside I and cynanauriculoside II, were isolated from the roots of Cynanchum aurichulatum. Their structures were established using spectroscopic methods including one and two-dimensional NMR.
文摘A new C21 steroidal glycoside, named cynanversicoside F （1）, was isolated from the root of Cynanchum versicolor Bunge. Its structure was established as glaucogenin-A 3-O-β-D- digitoxopyranosyl-（1→4）-β-D-cymaropyranoside by spectroscopic and chemical methods.
基金National Natural Science Foundation of China(30572322)Natural Science Foundation of Yunnan Province(2005C0036Q)
文摘Objective To investigate the chemical structures of glycosides in the roots of Cynanchum otophyllum（Asclepiadaceae） and to find new glycosides. Methods The total glycosides in the roots of C. olophyllum were separated by silica gel column chromatography. The structures of the resulting compounds were determined by NMR and FAB-MS spectra. Results Three C21 steroidal glycosides were separated. Their structures were determined as caudatin 3-O-（4-O-methyl-β-D-cymaropyranosyl）-（1→4）-ɑ-D-oleandropyranosyl-（1→4）-β-D-glucopyranosyl-（1→4）-ɑ-L-rhamnopyranoside（1）, caudatin 3-O-β-D-digitoxopyranosyl-（1→4）-ɑ-D-oleandropyranosyl-（1→4）-β-Ddiginopyranosyl-（1→4）-β-D-glucopyranoside（2）, and caudatin 3-O-β-D-diginopyranosyl-（1→4）-ɑ-D-oleandropyranosyl-（1→4）-ɑ-D-oleandropyranosyl-（1→4）-β-Dglucopyranoside（3）, respectively. Conclusion Glycosides 1-3 are new compounds.
基金National Natural Science Foundation of China (30572322)Natural Science Foundation of Yunnan Province (2005C0036Q)
文摘Objective To investigate the structures of compounds in the rhizome of Cynanchum otophyllum（Asclepiadaceae）, and to find new C21 steroidal glycosides. Methods The ethyl acetate extract from the rhizome was subjected to acidic hydrolysis and isolated by column chromatography; The structures of the purified compounds were determined by spectral methods. Literature search confirmed whether those compounds were of new structures. Results Three compounds were isolated and their structures were deacetylmetaplexigenin 3-O-β-D-oleandropyranosyl-（1→4）-α-D-oleandropyranosyl-（1→4）-α-D-oleandropyranoside（1）, deacetylmetaplexigenin 3-O-α-D-oleandropyranosyl-（1→4）-β-D-thevetopyranosyl-（1→4）-α-D-oleandropyranoside（2）, and deacetylmeta-plexigenin 3-O-β-D-cymaropyranosyl-（1→4）-α-D-oleandropyranoside（3）, respectively. Conclusion Compounds 1-3 are new compounds.
