Numerous emerging development areas worldwide are receiving attention;however,current research on land use change simulation primarily concentrates on cities,urban clusters,or larger scales.Moreover,there is a limited...Numerous emerging development areas worldwide are receiving attention;however,current research on land use change simulation primarily concentrates on cities,urban clusters,or larger scales.Moreover,there is a limited focus on understanding the impact of regional connectivity with surrounding cities and policy factors on land use change in these new areas.In this context,the present study utilizes a cellular automata(CA)model to investigate land use changes in the case of Nansha New District in Guangzhou,China.Three scenarios are examined,emphasizing conventional locational factors,policy considerations,and the influence of regional connectivity with surrounding cities.The results reveal several key findings:(1)Between 2015 and 2021,Nansha New District experienced significant land use changes,with the most notable shifts observed in cultivated land,water area,and construction land.(2)The comprehensive scenario exhibited the highest simulation accuracy,indicating that Nansha New District,as an emerging area,is notably influenced by policy factors and regional connectivity with surrounding cities.(3)Predictions for land use changes in Nansha by 2030,based on the scenario with the highest level of simulation accuracy,suggest an increase in the proportion of cultivated and forest land areas,alongside a decrease in the proportion of construction land and water area.This study contributes valuable insights to relevant studies and policymakers alike.展开更多
The Qilian mountain area was examined for using the Logistic-CA-Markov coupling model combined with GIS spatial analyst technology to research the transformation of LUCC, driving force system and simulate future tende...The Qilian mountain area was examined for using the Logistic-CA-Markov coupling model combined with GIS spatial analyst technology to research the transformation of LUCC, driving force system and simulate future tendency of variation. Results show that： （1） Woodland area decreased by 12.55%, while grassland, cultivated land, and settlement areas increased by 0.22%, 7.92%, and 0.03%, respectively, from 1986 to 2014. During the period of 1986 to 2000, forest degradation in the middle section of the mountain area decreased by 1,501.69 km2. Vegetation cover area improved, with a net increase of grassland area of 38.12 km2 from 2000 to 2014. （2） For constructing the system driving force, the best simulation scale was 210m×210m. Based on logistic regression analysis, the contribution （weight） of composite driving forces to land use and cover change was obtained, and the weight value was more objectively compared with AHP and MCE method. （3） In the natural scenarios, it is predicted that land use and cover distribution maps of Qilian mountain area in 2028 and 2042, and the Lee-Sallee index test was adopted. Over the next 27 years （2015-2042）, farmland, woodland, grassland, settlement areas show an increasing trend, especially settlements with an obvious change of 0.56%. The area of bare land will decrease by 0.89%. Without environmental degradation, tremendous structural change of LUCC will not occur, and typical characteristic of the vertical zone of the mountain would remain. Farmland and settlement areas will increase, but only in the vicinity of Qilian and Sunan counties.展开更多
In this study, the transmission capacity of VANETs in a highway scenario is analysed on the basis of a 1D line model and the carrier sense multiple access with collision avoidance(CSMA/CA) protocol. We describe the CS...In this study, the transmission capacity of VANETs in a highway scenario is analysed on the basis of a 1D line model and the carrier sense multiple access with collision avoidance(CSMA/CA) protocol. We describe the CSMA/CA protocol used in IEEE802.11 p from the perspective of the geometric relationship amongst simultaneous transmitters. The desired channel and interfering channels are assumed to experience the same amount of path-loss and Rayleigh fading. On the basis of the proposed model, we analyse the attempted transmission probability of each road segment and the maximum intensity of active transmitters, including their theoretical values. Then, we employ the physical model to obtain the outage probability and derive the upper bound of the transmission capacity of a VANET, which is defined as the average spatial density of successful transmissions in the network. Simulation results indicate that the theoretical value offers a good bound on network capacity.展开更多
Ca^2＋ dysregulation is an early event observed in Alzheimer＇s disease（AD） patients preceding the presence of its clinical symptoms.Dysregulation of neuronalCa^2＋ will cause synaptic loss and neuronal death,eventu...Ca^2＋ dysregulation is an early event observed in Alzheimer＇s disease（AD） patients preceding the presence of its clinical symptoms.Dysregulation of neuronalCa^2＋ will cause synaptic loss and neuronal death,eventually leading to memory impairments and cognitive decline.Treatments targetingCa^2＋ signaling pathways are potential therapeutic strategies against AD.The complicated interactions make it challenging and expensive to study the underlying mechanisms as to how Ca^2＋ signaling contributes to the pathogenesis of AD.Computational modeling offers new opportunities to study the signaling pathway and test proposed mechanisms.In this mini-review,we present some computational approaches that have been used to study Ca^2＋ dysregulation of AD by simulating Ca^2＋signaling at various levels.We also pointed out the future directions that computational modeling can be done in studying the Ca^2＋ dysregulation in AD.展开更多
基金This research received was funded by the National Natural Science Foundation of China(Grant No.42271217)the Guangdong Planning Office of Philosophy and Social Science(Grant No.GD21CGL15).
文摘Numerous emerging development areas worldwide are receiving attention;however,current research on land use change simulation primarily concentrates on cities,urban clusters,or larger scales.Moreover,there is a limited focus on understanding the impact of regional connectivity with surrounding cities and policy factors on land use change in these new areas.In this context,the present study utilizes a cellular automata(CA)model to investigate land use changes in the case of Nansha New District in Guangzhou,China.Three scenarios are examined,emphasizing conventional locational factors,policy considerations,and the influence of regional connectivity with surrounding cities.The results reveal several key findings:(1)Between 2015 and 2021,Nansha New District experienced significant land use changes,with the most notable shifts observed in cultivated land,water area,and construction land.(2)The comprehensive scenario exhibited the highest simulation accuracy,indicating that Nansha New District,as an emerging area,is notably influenced by policy factors and regional connectivity with surrounding cities.(3)Predictions for land use changes in Nansha by 2030,based on the scenario with the highest level of simulation accuracy,suggest an increase in the proportion of cultivated and forest land areas,alongside a decrease in the proportion of construction land and water area.This study contributes valuable insights to relevant studies and policymakers alike.
基金supported by National Natural Science Foundation of China (No. 4961038)Natural Science Foundation of Sichuan Province Education Department (No. 16ZB0402)+1 种基金Engineering and Technical College of Chengdu University of Technology Foundation (No. C122014014)the key research projects of Science and Technology Bureau of Leshan Town
文摘The Qilian mountain area was examined for using the Logistic-CA-Markov coupling model combined with GIS spatial analyst technology to research the transformation of LUCC, driving force system and simulate future tendency of variation. Results show that： （1） Woodland area decreased by 12.55%, while grassland, cultivated land, and settlement areas increased by 0.22%, 7.92%, and 0.03%, respectively, from 1986 to 2014. During the period of 1986 to 2000, forest degradation in the middle section of the mountain area decreased by 1,501.69 km2. Vegetation cover area improved, with a net increase of grassland area of 38.12 km2 from 2000 to 2014. （2） For constructing the system driving force, the best simulation scale was 210m×210m. Based on logistic regression analysis, the contribution （weight） of composite driving forces to land use and cover change was obtained, and the weight value was more objectively compared with AHP and MCE method. （3） In the natural scenarios, it is predicted that land use and cover distribution maps of Qilian mountain area in 2028 and 2042, and the Lee-Sallee index test was adopted. Over the next 27 years （2015-2042）, farmland, woodland, grassland, settlement areas show an increasing trend, especially settlements with an obvious change of 0.56%. The area of bare land will decrease by 0.89%. Without environmental degradation, tremendous structural change of LUCC will not occur, and typical characteristic of the vertical zone of the mountain would remain. Farmland and settlement areas will increase, but only in the vicinity of Qilian and Sunan counties.
基金supported in part by the National Natural Science Foundation of China under Grant No.61271184 and 61571065
文摘In this study, the transmission capacity of VANETs in a highway scenario is analysed on the basis of a 1D line model and the carrier sense multiple access with collision avoidance(CSMA/CA) protocol. We describe the CSMA/CA protocol used in IEEE802.11 p from the perspective of the geometric relationship amongst simultaneous transmitters. The desired channel and interfering channels are assumed to experience the same amount of path-loss and Rayleigh fading. On the basis of the proposed model, we analyse the attempted transmission probability of each road segment and the maximum intensity of active transmitters, including their theoretical values. Then, we employ the physical model to obtain the outage probability and derive the upper bound of the transmission capacity of a VANET, which is defined as the average spatial density of successful transmissions in the network. Simulation results indicate that the theoretical value offers a good bound on network capacity.
文摘Ca^2＋ dysregulation is an early event observed in Alzheimer＇s disease（AD） patients preceding the presence of its clinical symptoms.Dysregulation of neuronalCa^2＋ will cause synaptic loss and neuronal death,eventually leading to memory impairments and cognitive decline.Treatments targetingCa^2＋ signaling pathways are potential therapeutic strategies against AD.The complicated interactions make it challenging and expensive to study the underlying mechanisms as to how Ca^2＋ signaling contributes to the pathogenesis of AD.Computational modeling offers new opportunities to study the signaling pathway and test proposed mechanisms.In this mini-review,we present some computational approaches that have been used to study Ca^2＋ dysregulation of AD by simulating Ca^2＋signaling at various levels.We also pointed out the future directions that computational modeling can be done in studying the Ca^2＋ dysregulation in AD.
