The true stress-strain curves of Ti-6Al-2Zr-1Mo-1V alloy were achieved by a series of isothermal compression tests with height reduction of 60% under the deformation temperatures of 1073-1323 K and the strain rates of...The true stress-strain curves of Ti-6Al-2Zr-1Mo-1V alloy were achieved by a series of isothermal compression tests with height reduction of 60% under the deformation temperatures of 1073-1323 K and the strain rates of 0.01-10s 1.The critical conditions for the onset of DRX were attained when the value of d /d,where strain hardening rate d /d,reached the minimum which corresponds to an inflection of θ versus σ curve.Thus,two important potential parameters,critical strain and critical stress,were identified,and expressed as εc/εp=0.37-0.60,σc/σp=0.81-0.91.Furthermore,by the regression analysis for conventional hyperbolic sine equation,the main material parameters such as α,β,n,and DRX activation energy,Q,were calculated.In addition,the evolution of Q with strain rate and temperature was revealed as a 3D response surface.展开更多
The influence of different lubricants on the deformation behaviour of IN 718 alloy was studied. The results show that, with the improvement of lubrication condition, the deformation of the alloy tends to be homogeneou...The influence of different lubricants on the deformation behaviour of IN 718 alloy was studied. The results show that, with the improvement of lubrication condition, the deformation of the alloy tends to be homogeneous, and the resistance of deformation decreases. Consequently, FR 2 glass lubricant is considered to be an ideal choice when the relationship between stress and strain of IN 718 alloy is measured by means of hot compression experiment.展开更多
Resistance/sensitivity to polymyxin-B(PB)antibiotic has been employed as one among other epidemiologically relevant biotyping-scheme for Vibrio cholerae into Classical/El Tor biotypes.However,recent studies have re-ve...Resistance/sensitivity to polymyxin-B(PB)antibiotic has been employed as one among other epidemiologically relevant biotyping-scheme for Vibrio cholerae into Classical/El Tor biotypes.However,recent studies have re-vealed some pitfalls bordering on PB-sensitivity/resistance(PBR/S)necessitating study.Current study assesses the PBR/S cosmopolitan prevalence,epidemiology/distribution among O1/O139 and nonO1/nonO139 V.cholerae strains.Relevant databases(Web of Science,Scopus and PubMed)were searched to retrieve data from environ-mental and clinical samples employing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA).Random-effect-model(REM)and common-effect-model(CEM)of meta-analysis was performed to de-termine prevalence of PBR/S V.cholerae strains,describe the cosmopolitan epidemiological potentials and biotype relevance.Heterogeneity was determined by meta-regression and subgroup analyses.The pooled analyzed iso-lates from articles(7290),with sensitive and resistance are 2219(30.44%)and 5028(69.56%).Among these PB-sensitive strains,more than 1944(26.67%)were O1 strains,132(1.81%)were nonO1 strains while mis-reported Classical biotype were 2080(28.53)respectively indicating potential spread of variant/dual biotype.A significant PB-resistance was observed in the models(CEM=0.66,95%CI[0.65;0.68],p-value=0.001;REM=0.83[0.74;0.90],p=0.001)as both models had a high level of heterogeneity(I^(2)=98.0%;^(2)_(df=33)=1755.09,Qp=2.4932).Egger test(z=5.4017,p<0.0001)reveal publication bias by funnel plot asymmetry.The subgroup analysis for continents(Asia,Africa)and sources(acute diarrhea)revealed(98%CI(0.73;0.93);55%CI(0.20;0.86)),and 92%CI(0.67;0.98).The Epidemiological prevalence for El tor/variant/dual biotype showed 88%CI(0.78;0.94)with O1 strains at 88%CI(0.78;0.94).Such global prevalence,distribution/spread of phenotypes/genotypes ne-cessitates updating the decades-long biotype classification scheme.An antibiotic stewardship in the post antibiotic era is suggestive/recommended.Also,there is need for holistic monitoring/evaluation of clinical/epidemiological relevance of the disseminating strains in endemic localities.展开更多
基金Project(2012ZX04010081)supported by the National Key Technologies R&D Program of ChinaProject(cstc2009aa3012-1)supported by the Science and Technology Committee of Chongqing,ChinaProject(CDJZR12130045)supported by the Fundamental Research Funds for the Central Universities,China
文摘The true stress-strain curves of Ti-6Al-2Zr-1Mo-1V alloy were achieved by a series of isothermal compression tests with height reduction of 60% under the deformation temperatures of 1073-1323 K and the strain rates of 0.01-10s 1.The critical conditions for the onset of DRX were attained when the value of d /d,where strain hardening rate d /d,reached the minimum which corresponds to an inflection of θ versus σ curve.Thus,two important potential parameters,critical strain and critical stress,were identified,and expressed as εc/εp=0.37-0.60,σc/σp=0.81-0.91.Furthermore,by the regression analysis for conventional hyperbolic sine equation,the main material parameters such as α,β,n,and DRX activation energy,Q,were calculated.In addition,the evolution of Q with strain rate and temperature was revealed as a 3D response surface.
文摘The influence of different lubricants on the deformation behaviour of IN 718 alloy was studied. The results show that, with the improvement of lubrication condition, the deformation of the alloy tends to be homogeneous, and the resistance of deformation decreases. Consequently, FR 2 glass lubricant is considered to be an ideal choice when the relationship between stress and strain of IN 718 alloy is measured by means of hot compression experiment.
基金funds provided by African German Network of Excellence in Science 2022 (AGNES-2022).
文摘Resistance/sensitivity to polymyxin-B(PB)antibiotic has been employed as one among other epidemiologically relevant biotyping-scheme for Vibrio cholerae into Classical/El Tor biotypes.However,recent studies have re-vealed some pitfalls bordering on PB-sensitivity/resistance(PBR/S)necessitating study.Current study assesses the PBR/S cosmopolitan prevalence,epidemiology/distribution among O1/O139 and nonO1/nonO139 V.cholerae strains.Relevant databases(Web of Science,Scopus and PubMed)were searched to retrieve data from environ-mental and clinical samples employing the Preferred Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA).Random-effect-model(REM)and common-effect-model(CEM)of meta-analysis was performed to de-termine prevalence of PBR/S V.cholerae strains,describe the cosmopolitan epidemiological potentials and biotype relevance.Heterogeneity was determined by meta-regression and subgroup analyses.The pooled analyzed iso-lates from articles(7290),with sensitive and resistance are 2219(30.44%)and 5028(69.56%).Among these PB-sensitive strains,more than 1944(26.67%)were O1 strains,132(1.81%)were nonO1 strains while mis-reported Classical biotype were 2080(28.53)respectively indicating potential spread of variant/dual biotype.A significant PB-resistance was observed in the models(CEM=0.66,95%CI[0.65;0.68],p-value=0.001;REM=0.83[0.74;0.90],p=0.001)as both models had a high level of heterogeneity(I^(2)=98.0%;^(2)_(df=33)=1755.09,Qp=2.4932).Egger test(z=5.4017,p<0.0001)reveal publication bias by funnel plot asymmetry.The subgroup analysis for continents(Asia,Africa)and sources(acute diarrhea)revealed(98%CI(0.73;0.93);55%CI(0.20;0.86)),and 92%CI(0.67;0.98).The Epidemiological prevalence for El tor/variant/dual biotype showed 88%CI(0.78;0.94)with O1 strains at 88%CI(0.78;0.94).Such global prevalence,distribution/spread of phenotypes/genotypes ne-cessitates updating the decades-long biotype classification scheme.An antibiotic stewardship in the post antibiotic era is suggestive/recommended.Also,there is need for holistic monitoring/evaluation of clinical/epidemiological relevance of the disseminating strains in endemic localities.
