At the Juncture of China's Entry to WTO, An Overall Development of Foreign Economic Relations andTrade Will Be Carried out in XPCC

The Xinjiang Production andConstruction Corps (XPCC) was foundedin October 1954. Since 1990, its plan hasbeen listed directly under the state councilof PRC.After 50 years of arduouspioneering and development, the XPCChas now developed to be a specialorganization with a solid economicstrength and enterprise group superiority,which is based on the large-scale andmodernized agriculture, and guided

A Successful Piggyback Microgravity Experiment Carried out by China for Japan

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基于FPGA的单光子时间数字转换器设计

针对单光子计数器对高速飞行光子时间测量的高分辨率要求,传统的TDC在时间测量上存在误差较大的不足。本文设计了一种利用FPGA内部逻辑延迟单元Carry4级联构建延迟链的TDC。该方法首先使用子链平均的方式进行数据采样,避免数据“气泡”。其次,结合码密度测试和bin-by-bin校准将各级延迟单元宽度校准至接近均匀宽度,提高系统的测量精度。最后,通过Vivado软件仿真并烧录至ZYNQ7000进行板级测试,实验结果表明,该TDC能够在3 ns的动态时间范围内实现时间分辨率10.91 ps,差分非线性(DNL)范围为[-0.75,1.01]LSB,积分非线性(INL)范围为[-1.74,2.19]LSB。

Clustering of voltage-gated ion channels as an evolutionary trigger of myelin formation

Neurons carry apical dendrites that perceive information and a basal axon that transmits the computed information towards its to rgets.The axon originates at the axon hillock which is followed by the axon initial segment.Here,action potentials are initiated that are based on millisecond long openings of specific voltagegated sodium and potassium channels that are conserved in all parahoxozoa(Placozoa,Cnidaria,Bilateria)(Li et al.,2015).

A NovelMethod for Determining Tourism Carrying Capacity in a Decision-Making Context Using q−Rung Orthopair Fuzzy Hypersoft Environment

Tourism is a popular activity that allows individuals to escape their daily routines and explore new destinations for various reasons,including leisure,pleasure,or business.A recent study has proposed a unique mathematical concept called a q−Rung orthopair fuzzy hypersoft set(q−ROFHS)to enhance the formal representation of human thought processes and evaluate tourism carrying capacity.This approach can capture the imprecision and ambiguity often present in human perception.With the advanced mathematical tools in this field,the study has also incorporated the Einstein aggregation operator and score function into the q−ROFHS values to supportmultiattribute decision-making algorithms.By implementing this technique,effective plans can be developed for social and economic development while avoiding detrimental effects such as overcrowding or environmental damage caused by tourism.A case study of selected tourism carrying capacity will demonstrate the proposed methodology.

The Quest for Haven in Sister Carrie

This essay analyses Theodore Dreiser’s Sister Carrie through the lens of cultural studies,examining the portrayal of domesticity and the quest for an ideal home in late-nineteenth-century America.It explores the complex relationships between the main characters,Carrie and Hurstwood,and their families,as well as their struggles with materialism and alienation.Through close analysis of societal context,the characters’familial backgrounds and emotional yearnings,the essay delves into the characters’longing for stability and belonging and their journey toward understanding the true essence of dwelling amidst the changing urban landscape.It argues that Dreiser’s novel critiques the superficial pursuit of material comforts and highlights the importance of introspection and self-discovery in finding lasting happiness amidst societal turmoil.Ultimately,through the prism of domesticity,the essay delves into broader themes of identity,belonging,and existential fulfillment in a heartless society marked by materialism and alienation.

2024 ‘Happy Chinese New Year’ Tour Performance in 4 European Countries by China National Opera & Dance Drama Theater

During the Chinese New Year of 2024,China National Opera&Dance Drama Theater was invited to Hungary,Sweden,Denmark and Norway to carry out the 2024"Happy Chinese NewYear"tour performance.China National Opera&Dance Drama Theater sent a visiting team composed of 29 artists to touch the hearts of overseas audiences with the art of ethnic singing and dancing and the deep charm of the Chinese culture,and to spread the essence of the Chinese culture in the dialogue with the world.

Microvesicles with mitochondrial content are increased in patients with sepsis and associated with inflammatory responses

BACKGROUND Endothelial activation plays an important role in sepsis-mediated inflammation,but the triggering factors have not been fully elucidated.Microvesicles carrying mitochondrial content(mitoMVs)have been implicated in several diseases and shown to induce endothelial activation.AIM To explore whether mitoMVs constitute a subset of MVs isolated from plasma of patients with sepsis and contribute to endothelial activation.METHODS MVs were isolated from human plasma and characterized by confocal microscopy and flow cytometry.Proinflammatory cytokines,including interleukin(IL)-6,IL-8 and tumour necrosis factor(TNF)-α,and soluble vascular cell adhesion molecule(sVCAM)-1 were detected by ELISA.Human umbilical vein endothelial cells(HUVECs)were stimulated with the circulating MVs to evaluate their effect on endothelial activation.RESULTS MitoMVs were observed in plasma from patients with sepsis.Compared with those in healthy controls,expression of MVs,mitoMVs,proinflammatory cytokines and sVCAM-1 was increased.The number of mitoMVs was positively associated with TNF-αand sVCAM-1.In vitro,compared with MVs isolated from the plasma of healthy controls,MVs isolated from the plasma of patients with sepsis induced expression of OAS2,RSAD2,and CXCL10 in HUVECs.MitoMVs were taken up by HUVECs,and sonication of MVs significantly reduced the uptake of mitoMVs by HUVECs and expression of the above three type I IFNdependent genes.CONCLUSION MitoMVs are increased in the plasma of patients with sepsis,which induces elevated expression of type I IFN-dependent genes.This suggests that circulating mitoMVs activate the type I IFN signalling pathway in endothelial cells and lead to endothelial activation.

A Model Predictive Control Algorithm Based on Biological Regulatory Mechanism and Operational Research

Dear Editor,This letter presents an intelligent model predictive control algorithm inspired by biological regulatory mechanism and operational research. In terms of overall architecture, based on biological regulatory system and operational research theory, priority factor module and central coordination module are innovatively added on the basis structure of heuristic dynamic programming to carry out overall regulation of the system.

Integrated water risk early warning framework of the semi-arid transitional zone based on the water environmental carrying capacity (WECC)

Water risk early warning systems based on the water environmental carrying capacity(WECC)are powerful and effective tools to guarantee the sustainability of rivers.Existing work on the early warning of WECC has mainly concerned the comprehensive evaluation of the status quo and lacked a quantitative prejudgement and warning of future overload.In addition,existing quantitative methods for short-term early warning have rarely focused on the integrated change trends of the early warning indicators.Given the periodicity of the socioeconomic system,however,the water environmental system also follows a trend of cyclical fluctuations.Thus,it is meaningful to monitor and use this periodicity for the early warning of the WECC.In this study,we first adopted and improved the prosperity index method to develop an integrated water risk early warning framework.We also constructed a forecast model to qualitatively and quantitatively prejudge and warn about the development trends of the water environmental system.We selected the North Canal Basin(an essential connection among the Beijing-Tianjin-Hebei region)in China as a case study and predicted the WECC in 25 water environmental management units of the basin in 2018–2023.We found that the analysis of the prosperity index was helpful in predicting the WECC,to some extent.The result demonstrated that the early warning system provided reliable prediction(root mean square error of 0.0651 and mean absolute error of 0.1418),and the calculation results of the comprehensive early warning index(CEWI)conformed to the actual situation and related research in the river basin.From 2008 to 2023,the WECC of most water environmental management units in the basin had improved but with some spatial differences:the CEWI was generally poor in areas with many human disturbances,while it was relatively good in the upstream regions with higher forest and grass covers as well as in the downstream areas with larger water volume.Finally,through a sensitivity analysis of the indicators,we proposed specific management measures for the sustainability of the water environmental system in the North Canal Basin.Overall,the integrated water risk early warning framework could provide an appropriate method for the water environmental administration department to predict the WECC of the basin in the future.This framework could also assist in implementing corresponding management measures in advance,especially for the performance evaluation and the arrangement of key short-term tasks in the River Chief System in China.

Optimal Concentration of the Bubble Drainage Agent in Foam Drainage Gas Recovery Applications

Foam drainage is theflow of liquid through the interstitial spaces between bubbles driven by capillarity and grav-ity and resisted by viscous damping.The so-called foam drainage gas recovery technology is a technique tradi-tionally used to mitigate the serious bottom-hole liquid loading in the middle and late stages of gas well production.In this context,determining the optimal concentration of the bubble drainage agent is generally cru-cial for the proper application of this method.In this study,a combination of indoor experiments and theoretical analysis have been used to determine the pressure drop related to the foam-carrying capacity in a representative gasfield.Dynamic and static experiments were designed with a bubble drainage agent concentration varying in the range 0.3%–0.6%.Using thefield formation water data,the optimal soaking agent concentration was obtained and pressure drop test experiments on the foam carrying capacity were conducted accordingly.These tests have revealed that the optimal foam displacement agent concentration is 0.5%,and the foam quality at the optimum concentration is between 0.78–0.98.A theoretical method for calculating the pressure drop at the optimum soak-away concentration based on experimental data has also been introduced.The error of the proposed method is within 15%compared to the experimental measured value,demonstrating that it is highly accurate and simple.

Principles of Nanoparticle Delivery to Solid Tumors

The effective treatment of patients with cancer hinges on the delivery of therapeutics to a tumor site.Nanoparticles provide an essential transport system.We present 5 principles to consider when designing nanoparticles for cancer targeting:(a)Nanoparticles acquire biological identity in vivo,(b)organs compete for nanoparticles in circulation,(c)nanoparticles must enter solid tumors to target tumor components,(d)nanoparticles must navigate the tumor microenvironment for cellular or organelle targeting,and(e)size,shape,surface chemistry,and other physicochemical properties of nanoparticles influence their transport process to the target.This review article describes these principles and their application for engineering nanoparticle delivery systems to carry therapeutics to tumors or other disease targets.

Performance Measurement of Energy Efficient and Highly Scalable Hybrid Adder

The adders are the vital arithmetic operation for any arithmetic operations like multiplication,subtraction,and division.Binary number additions are performed by the digital circuit known as the adder.In VLSI(Very Large Scale Integration),the full adder is a basic component as it plays a major role in designing the integrated circuits applications.To minimize the power,various adder designs are implemented and each implemented designs undergo defined drawbacks.The designed adder requires high power when the driving capability is perfect and requires low power when the delay occurred is more.To overcome such issues and to obtain better performance,a novel parallel adder is proposed.The design of adder is initiated with 1 bit and has been extended up to 32 bits so as verify its scalability.This proposed novel parallel adder is attained from the carry look-ahead adder.The merits of this suggested adder are better speed,power consumption and delay,and the capability in driving.Thus designed adders are verified for different supply,delay,power,leakage and its performance is found to be superior to competitive Manchester Carry Chain Adder(MCCA),Carry Look Ahead Adder(CLAA),Carry Select Adder(CSLA),Carry Select Adder(CSA)and other adders.

Water resource utilization characteristics and driving factors in the Hainan Island

The scarcity of water resources caused by the unique topography and uneven rainfall distribution in Hainan Island has become a major factor restricting local development. In order to provide effective and scientific reference basis for the overall water resource utilization status and solving this problem, this study calculated the water resource utilization situation of Hainan Island from 2017 to 2021 in detail using methods including water resource ecological footprint analysis. Furthermore, a spatial correlation analysis was conducted to examine the island's water resource utilization characteristics, and the driving factors behind the changes in water resource utilization over the past five years were analyzed using the LMDI model. The results show that:(1) During the study period, the water resource ecological footprint in Hainan Island exhibited a slow growth trend, while the ecological carrying capacity showed a downward tendency.The per capita ecological deficit of water resources remains relatively high, and the water consumption per 10 000 yuan GDP in the whole land continues to decrease, indicating that the overall pressure on water resource demand remains high with significant regional differences accompanied by the efficiency of water resource utilization steadily improving at the same time;(2) Agricultural water use accounts for the highest proportion in the entire water use structure, while ecological water use represents the smallest share, with a year-on-year increase, indicating that Hainan Island highlights the agricultural development and is increasingly conscious of the ecological environment;(3) Significant spatial differentiation in water resource utilization characteristics exists in Hainan Island, with the western region being a hot spot aggregation area for per capita water resource ecological footprint, per capita ecological carrying capacity of water resources, water consumption per 10 000 yuan GDP, while it is a cold spot cluster area for per capita ecological deficit of water resources. The opposite holds true for the eastern region of Hainan Island;(4) Economic and technological factors have a major impact on the changes in water resource ecological footprint within the designated area. Among them, economic factors drive the growth of the water resource ecological footprint in Hainan Island, and exacerbate local water resource consumption, while technological factors negatively contribute to the amount of water resource utilization in Hainan Island, indicating that advanced technology has improved water resource utilization efficiency and significantly reduced water resource consumption.

Analysis of the Concept of Environmental Carrying Capacity

From the concept of carrying capacity proposed in the early 20th century to as an important tool for describing development constraints in the 21st century,many scholars have conducted extensive and detailed research on carrying capacity at different levels,but the carrying capacity system has not yet formed a unified theoretical and methodological system.By summarizing and analyzing the existing literature,based on the viewpoints of Mr.Gao Jixi and Mr.Zeng Weihua,the relationship between different mainstream carrying capacities is analyzed,and finally a system for summarizing the elements of different carrying capacities is provided,which to some extent serves as a reference for scholars who have just come into contact with the concept of carrying capacity.It is thought that:①the research on ecological carrying capacity covers the scope of cities,and the research at the urban level complements the neglected and insufficient areas of ecological research.②The main difference among ecological carrying capacity,urban comprehensive carrying capacity and resource environment carrying capacity lies in the different research scopes.In the mainstream view,environmental carrying capacity and resource carrying capacity are summarized under the framework of different research scopes.Water environment carrying capacity,land resource carrying capacity and other single factor carrying capacity are special in-depth studies of environment and resource carrying capacity.③Ecological carrying capacity at the ecological level includes environmental carrying capacity and resource carrying capacity.At the urban level,urban ecology is equivalent to urban environment to a certain extent,and resources can be classified into urban environmental carrying capacity as an environmental element.

Analysis of Pollutant Load Carrying Capacity of the River Tapi Using QUAL2Kw for Surat City

River Tapi is the prime water body for Surat city, Gujarat, India. On a long stretch of 22.39 km in Surat city (Kamrej to Causeway) of the Tapi river, there are many identified and non-identified discharge points available. Excessive discharge from these points restricts the efficiency of the self-purification process which ultimately degrades the river water quality. In this paper, an attempt has been made to estimate the pollutant load-carrying capacity at different segments of the river Tapi using the QUAL2Kw tool. The study has been undertaken with different scenarios: First, the QUAL2Kw model was trained with available river water quality and hydraulic data of the Tapi river in which the complete river segment was divided into 21 reaches. The model was calibrated and validated with the actual concentrations of the pollutants entering. In the second phase, all the point source, non-point source, and headwater characteristics were considered and the pollutant load-carrying capacity of the river in terms of BOD, ISS, and N-nitrate was found. In the third phase, all the sources of pollutants entering the river have been removed and only headwater characteristics were considered for the study. The results indicate that reach no. 21 (21.23ºN, 72.82ºE) has the maximum load-carrying capacity of Biochemical Oxygen Demand (BOD) up to 2057.7 kg/day, Inorganic Suspended Solids (ISS) up to 85633.8 kg/day, and Nitrate (NO3) up to 31688.8 kg/day. However, reach no. 4 has the minimum load carrying capacity of BOD up to 1088.1 kg/day, reach 8 carries a minimum of ISS 205341.6 kg/day and NO3 10215.57 kg/day.

Evaluation of Water Resources Carrying Capacity in Gansu Section of Yellow River Basin Based on Fuzzy Comprehensive Evaluation Model

As a basic natural resource and strategic economic resource,the development and utilization of water resources is an important issue related to the national economy and people's livelihood.How to scientifically evaluate the water resources carrying capacity is the premise to improve the regional water resources carrying capacity and ensure the regional water security.The Gansu section of the Yellow River basin is an important water conservation and recharge area.Whether the water resources in this area can ensure the normal operation of the ecosystem and whether it can carry the sustainable development of social economy is the key to realize the high-quality development of the Yellow River basin.In this study,from the three dimensions of water consumption per capita,water consumption of 10000 yuan GDP and ecological water use rate,by constructing the evaluation index system and index grading standard of water resources carrying capacity,the fuzzy comprehensive evaluation model was used to evaluate the water resources carrying capacity of Gansu section of the Yellow River Basin,in order to provide theoretical decision-making basis for the comprehensive development,utilization and planning management of water resources in Gansu section of the Yellow River basin and even the whole basin,and help the high-quality development of the Yellow River basin.

Exploring the Goal Synergy between the Ecological Carrying Capacity of Miyun District and the Development of the Ecological Home-stay Industry in Beijing

Green construction in culture and environmental protection will be the development trend in a long run,the urban and suburban area will be ecologically developed as well.Rural revitalization must adhere to the position of historical progress theory and modern concepts,innovate spatial layout,optimize ecological resources,and appropriately determine its historical significance and sustainable development responsibility with reasonable value orientation and environmental ecological carrying capacity for local ecological construction.In order to achieve this responsibility,the authors must expand the dimensions to consider more relevant factors.The guarantee of ecological carrying capacity is an important means to ensure the promotion of ecological civilization.This paper aims to integrate and regulate the goal synergy of the cultural development of the home-stay industry in Miyun District of Beijing by means of the innovative model of sustainable economic development of cultural ecology,ecological people,ecological health preservation and rich home-stay ecological elements.Assuming that the role of the former in promoting the latter can be expanded,then in the range of ecological and cultural towns(conceptual model)that maintain a certain tolerance of ecological carrying capacity,as a characteristic home-stay industry in Miyun,there will be some effective growth,so the integration and development of multiple cultural genes and elements must be the ecological and cultural town model under the enhanced multi-factor aggregation effect,(See the ecological environment carrying capacity development goal A:A=B12345+C1234567 later).This article will explain that the development goals of Miyun's ecological culture and the ecological homestay industry are coordinated,and the two are mutually raised in the same direction.

SCIENCE AND TECHNOLOGY

Departing from east China’s Shandong Province,an intelligent research vessel named Haitun 1 started its maiden voyage on June 30.Developed by the Harbin Engineering University in northeast China’s Heilongjiang Province,Haitun 1(or Dolphin 1)is 25 meters long with a displacement of 100 tonnes.It is equipped with digital twin technology and will carry out a series of experiments through­out its voyage.