This article introduces a novel variant of the generalized linear exponential(GLE)distribution,known as the sine generalized linear exponential(SGLE)distribution.The SGLE distribution utilizes the sine transformation ...This article introduces a novel variant of the generalized linear exponential(GLE)distribution,known as the sine generalized linear exponential(SGLE)distribution.The SGLE distribution utilizes the sine transformation to enhance its capabilities.The updated distribution is very adaptable and may be efficiently used in the modeling of survival data and dependability issues.The suggested model incorporates a hazard rate function(HRF)that may display a rising,J-shaped,or bathtub form,depending on its unique characteristics.This model includes many well-known lifespan distributions as separate sub-models.The suggested model is accompanied with a range of statistical features.The model parameters are examined using the techniques of maximum likelihood and Bayesian estimation using progressively censored data.In order to evaluate the effectiveness of these techniques,we provide a set of simulated data for testing purposes.The relevance of the newly presented model is shown via two real-world dataset applications,highlighting its superiority over other respected similar models.展开更多
A class of estimators of the mean survival time with interval censored data are studied by unbiased transformation method. The estimators are constructed based on the observations to ensure unbiasedness in the sense t...A class of estimators of the mean survival time with interval censored data are studied by unbiased transformation method. The estimators are constructed based on the observations to ensure unbiasedness in the sense that the estimators in a certain class have the same expectation as the mean survival time. The estimators have good properties such as strong consistency (with the rate of O(n^-1/1 (log log n)^1/2)) and asymptotic normality. The application to linear regression is considered and the simulation reports are given.展开更多
This paper considers the local linear regression estimators for partially linear model with censored data. Which have some nice large-sample behaviors and are easy to implement. By many simulation runs, the author als...This paper considers the local linear regression estimators for partially linear model with censored data. Which have some nice large-sample behaviors and are easy to implement. By many simulation runs, the author also found that the estimators show remarkable in the small sample case yet.展开更多
Type-I censoring mechanism arises when the number of units experiencing the event is random but the total duration of the study is fixed. There are a number of mathematical approaches developed to handle this type of ...Type-I censoring mechanism arises when the number of units experiencing the event is random but the total duration of the study is fixed. There are a number of mathematical approaches developed to handle this type of data. The purpose of the research was to estimate the three parameters of the Frechet distribution via the frequentist Maximum Likelihood and the Bayesian Estimators. In this paper, the maximum likelihood method (MLE) is not available of the three parameters in the closed forms;therefore, it was solved by the numerical methods. Similarly, the Bayesian estimators are implemented using Jeffreys and gamma priors with two loss functions, which are: squared error loss function and Linear Exponential Loss Function (LINEX). The parameters of the Frechet distribution via Bayesian cannot be obtained analytically and therefore Markov Chain Monte Carlo is used, where the full conditional distribution for the three parameters is obtained via Metropolis-Hastings algorithm. Comparisons of the estimators are obtained using Mean Square Errors (MSE) to determine the best estimator of the three parameters of the Frechet distribution. The results show that the Bayesian estimation under Linear Exponential Loss Function based on Type-I censored data is a better estimator for all the parameter estimates when the value of the loss parameter is positive.展开更多
An empirical likelihood approach to estimate the coefficients in linear model with interval censored responses is developed in this paper. By constructing unbiased transformation of interval censored data,an empirical...An empirical likelihood approach to estimate the coefficients in linear model with interval censored responses is developed in this paper. By constructing unbiased transformation of interval censored data,an empirical log-likelihood function with asymptotic X^2 is derived. The confidence regions for the coefficients are constructed. Some simulation results indicate that the method performs better than the normal approximation method in term of coverage accuracies.展开更多
In this paper, based on random left truncated and right censored data, the authors derive strong representations of the cumulative hazard function estimator and the product-limit estimator of the survival function. wh...In this paper, based on random left truncated and right censored data, the authors derive strong representations of the cumulative hazard function estimator and the product-limit estimator of the survival function. which are valid up to a given order statistic of the observations. A precise bound for the errors is obtained which only depends on the index of the last order statistic to be included.展开更多
This paper aims to explore the application of Extreme Value Theory (EVT) in estimating the conditional extreme quantile for time-to-event outcomes by examining the functional relationship between ambulatory blood pres...This paper aims to explore the application of Extreme Value Theory (EVT) in estimating the conditional extreme quantile for time-to-event outcomes by examining the functional relationship between ambulatory blood pressure trajectories and clinical outcomes in stroke patients. The study utilizes EVT to analyze the functional connection between ambulatory blood pressure trajectories and clinical outcomes in a sample of 297 stroke patients. The 24-hour ambulatory blood pressure measurement curves for every 15 minutes are considered, acknowledging a censored rate of 40%. The findings reveal that the sample mean excess function exhibits a positive gradient above a specific threshold, confirming the heavy-tailed distribution of data in stroke patients with a positive extreme value index. Consequently, the estimated conditional extreme quantile indicates that stroke patients with higher blood pressure measurements face an elevated risk of recurrent stroke occurrence at an early stage. This research contributes to the understanding of the relationship between ambulatory blood pressure and recurrent stroke, providing valuable insights for clinical considerations and potential interventions in stroke management.展开更多
Based on left truncated and right censored dependent data, the estimators of higher derivatives of density function and hazard rate function are given by kernel smoothing method. When observed data exhibit α-mixing d...Based on left truncated and right censored dependent data, the estimators of higher derivatives of density function and hazard rate function are given by kernel smoothing method. When observed data exhibit α-mixing dependence, local properties including strong consistency and law of iterated logarithm are presented. Moreover, when the mode estimator is defined as the random variable that maximizes the kernel density estimator, the asymptotic normality of the mode estimator is established.展开更多
Empirical-likelihood-based inference for the parameters in a partially linear single-index model with randomly censored data is investigated. We introduce an estimated empirical likelihood for the parameters using a s...Empirical-likelihood-based inference for the parameters in a partially linear single-index model with randomly censored data is investigated. We introduce an estimated empirical likelihood for the parameters using a synthetic data approach and show that its limiting distribution is a mixture of central chi-squared distribution. To attack this difficulty we propose an adjusted empirical likelihood to achieve the standard X2-1imit. Furthermore, since the index is of norm 1, we use this constraint to reduce the dimension of parameters, which increases the accuracy of the confidence regions. A simulation study is carried out to compare its finite-sample properties with the existing method. An application to a real data set is illustrated.展开更多
In this paper an asymptotic distribution is obtained for the maximaldeviation between the kernel quantile density estimator and the quantile density when the data aresubject to random left truncation and right censors...In this paper an asymptotic distribution is obtained for the maximaldeviation between the kernel quantile density estimator and the quantile density when the data aresubject to random left truncation and right censorship. Based on this result we propose a fullysequential procedure for constructing a fixed-width confidence band for the quantile density on afinite interval and show that the procedure has the desired coverage probability asymptotically asthe width of the band approaches zero.展开更多
Abstract In this paper we consider a fixed design model in which the observations are subject to left truncation and right censoring. A generalized product-limit estimator for the conditional distribution at a given c...Abstract In this paper we consider a fixed design model in which the observations are subject to left truncation and right censoring. A generalized product-limit estimator for the conditional distribution at a given covariate value is proposed, and an almost sure asymptotic representation of this estimator is established. We also obtain the rate of uniform consistency, weak convergence and a modulus of continuity for this estimator. Applications include trimmed mean and quantile function estimators.These applications demonstrate the usefulness of the new matrix products.展开更多
In this paper, we give a detailed description of the local behavior of theLipschitz-1/2 modulus for cumulative hazard process and PL-process when the data are subject to lefttruncation and right censored observations....In this paper, we give a detailed description of the local behavior of theLipschitz-1/2 modulus for cumulative hazard process and PL-process when the data are subject to lefttruncation and right censored observations. We establish laws of the iterated logarithm of theLipschitz-1/2 modulus of PL-process and cumulative hazard process. These results for the PL-processare sharper than other results found in the literature, which can be used to establish theasymptotic properties of many statistics.展开更多
Consider a semiparametric regression model Y_i=X_iβ+g(t_i)+e_i, 1 ≤ i ≤ n, where Y_i is censored on the right by another random variable C_i with known or unknown distribution G. The wavelet estimators of param...Consider a semiparametric regression model Y_i=X_iβ+g(t_i)+e_i, 1 ≤ i ≤ n, where Y_i is censored on the right by another random variable C_i with known or unknown distribution G. The wavelet estimators of parameter and nonparametric part are given by the wavelet smoothing and the synthetic data methods. Under general conditions, the asymptotic normality for the wavelet estimators and the convergence rates for the wavelet estimators of nonparametric components are investigated. A numerical example is given.展开更多
Receiver operating characteristic (ROC) curves are often used to study the two sample problem in medical studies. However, most data in medical studies are censored. Usually a natural estimator is based on the Kapla...Receiver operating characteristic (ROC) curves are often used to study the two sample problem in medical studies. However, most data in medical studies are censored. Usually a natural estimator is based on the Kaplan-Meier estimator. In this paper we propose a smoothed estimator based on kernel techniques for the ROC curve with censored data. The large sample properties of the smoothed estimator are established. Moreover, deficiency is considered in order to compare the proposed smoothed estimator of the ROC curve with the empirical one based on Kaplan-Meier estimator. It is shown that the smoothed estimator outperforms the direct empirical estimator based on the Kaplan-Meier estimator under the criterion of deficiency. A simulation study is also conducted and a real data is analyzed.展开更多
In some situations,the failure time of interest is defined as the gap time between two related events and the observations on both event times can suffer either right or interval censoring.Such data are usually referr...In some situations,the failure time of interest is defined as the gap time between two related events and the observations on both event times can suffer either right or interval censoring.Such data are usually referred to as doubly censored data and frequently encountered in many clinical and observational studies.Additionally,there may also exist a cured subgroup in the whole population,which means that not every individual under study will experience the failure time of interest eventually.In this paper,we consider regression analysis of doubly censored data with a cured subgroup under a wide class of flexible transformation cure models.Specifically,we consider marginal likelihood estimation and develop a two-step approach by combining the multiple imputation and a new expectation-maximization(EM)algorithm for its implementation.The resulting estimators are shown to be consistent and asymptotically normal.The finite sample performance of the proposed method is investigated through simulation studies.The proposed method is also applied to a real dataset arising from an AIDS cohort study for illustration.展开更多
Published auxiliary information can be helpful in conducting statistical inference in a new study.In this paper,we synthesize the auxiliary information with semiparametric likelihood-based inference for censoring data...Published auxiliary information can be helpful in conducting statistical inference in a new study.In this paper,we synthesize the auxiliary information with semiparametric likelihood-based inference for censoring data with the total sample size is available.We express the auxiliary information as constraints on the regression coefficients and the covariate distribution,then use empirical likelihood method for general estimating equations to improve the efficiency of the interested parameters in the specified model.The consistency and asymptotic normality of the resulting regression parameter estimators established.Also numerical simulation and application with different supposed conditions show that the proposed method yields a substantial gain in efficiency of the interested parameters.展开更多
A kernel density estimator is proposed when tile data are subject to censorship in multivariate case. The asymptotic normality, strong convergence and asymptotic optimal bandwidth which minimize the mean square error ...A kernel density estimator is proposed when tile data are subject to censorship in multivariate case. The asymptotic normality, strong convergence and asymptotic optimal bandwidth which minimize the mean square error of the estimator are studied.展开更多
The maximum entropy method has been widely used in many fields, such as statistical mechanics,economics, etc. Its crucial idea is that when we make inference based on partial information, we must use the distribution ...The maximum entropy method has been widely used in many fields, such as statistical mechanics,economics, etc. Its crucial idea is that when we make inference based on partial information, we must use the distribution with maximum entropy subject to whatever is known. In this paper, we investigate the empirical entropy method for right censored data and use simulation to compare the empirical entropy method with the empirical likelihood method. Simulations indicate that the empirical entropy method gives better coverage probability than that of the empirical likelihood method for contaminated and censored lifetime data.展开更多
In survival analysis, the Kaplan-Meter estimator plays a very important role, and its asymptotic properties have been studied by many authors. In recefit years, people find that someimportant statistics can be express...In survival analysis, the Kaplan-Meter estimator plays a very important role, and its asymptotic properties have been studied by many authors. In recefit years, people find that someimportant statistics can be expressed as the integrals with respect to it. In this paper we shalldiscuss the asymptotic behavior of such integrals. The strong convergence rste shall be givenand the weak convergence result in space D shall be proved.展开更多
In this work,we consider the problem of estimating the parameters and predicting the unobserved or removed ordered data for the progressive type II censored flexible Weibull sample.Frequentist and Bayesian analyses ar...In this work,we consider the problem of estimating the parameters and predicting the unobserved or removed ordered data for the progressive type II censored flexible Weibull sample.Frequentist and Bayesian analyses are adopted for conducting the estimation and prediction problems.The likelihood method as well as the Bayesian sampling techniques is applied for the inference problems.The point predictors and credible intervals of unobserved data based on an informative set of data are computed.Markov ChainMonte Carlo samples are performed to compare the so-obtained methods,and one real data set is analyzed for illustrative purposes.展开更多
基金This work was supported and funded by the Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University(IMSIU)(Grant Number IMSIU-RG23142).
文摘This article introduces a novel variant of the generalized linear exponential(GLE)distribution,known as the sine generalized linear exponential(SGLE)distribution.The SGLE distribution utilizes the sine transformation to enhance its capabilities.The updated distribution is very adaptable and may be efficiently used in the modeling of survival data and dependability issues.The suggested model incorporates a hazard rate function(HRF)that may display a rising,J-shaped,or bathtub form,depending on its unique characteristics.This model includes many well-known lifespan distributions as separate sub-models.The suggested model is accompanied with a range of statistical features.The model parameters are examined using the techniques of maximum likelihood and Bayesian estimation using progressively censored data.In order to evaluate the effectiveness of these techniques,we provide a set of simulated data for testing purposes.The relevance of the newly presented model is shown via two real-world dataset applications,highlighting its superiority over other respected similar models.
基金Supported by the National Natural Science Foundation of China (70171008)
文摘A class of estimators of the mean survival time with interval censored data are studied by unbiased transformation method. The estimators are constructed based on the observations to ensure unbiasedness in the sense that the estimators in a certain class have the same expectation as the mean survival time. The estimators have good properties such as strong consistency (with the rate of O(n^-1/1 (log log n)^1/2)) and asymptotic normality. The application to linear regression is considered and the simulation reports are given.
文摘This paper considers the local linear regression estimators for partially linear model with censored data. Which have some nice large-sample behaviors and are easy to implement. By many simulation runs, the author also found that the estimators show remarkable in the small sample case yet.
文摘Type-I censoring mechanism arises when the number of units experiencing the event is random but the total duration of the study is fixed. There are a number of mathematical approaches developed to handle this type of data. The purpose of the research was to estimate the three parameters of the Frechet distribution via the frequentist Maximum Likelihood and the Bayesian Estimators. In this paper, the maximum likelihood method (MLE) is not available of the three parameters in the closed forms;therefore, it was solved by the numerical methods. Similarly, the Bayesian estimators are implemented using Jeffreys and gamma priors with two loss functions, which are: squared error loss function and Linear Exponential Loss Function (LINEX). The parameters of the Frechet distribution via Bayesian cannot be obtained analytically and therefore Markov Chain Monte Carlo is used, where the full conditional distribution for the three parameters is obtained via Metropolis-Hastings algorithm. Comparisons of the estimators are obtained using Mean Square Errors (MSE) to determine the best estimator of the three parameters of the Frechet distribution. The results show that the Bayesian estimation under Linear Exponential Loss Function based on Type-I censored data is a better estimator for all the parameter estimates when the value of the loss parameter is positive.
文摘An empirical likelihood approach to estimate the coefficients in linear model with interval censored responses is developed in this paper. By constructing unbiased transformation of interval censored data,an empirical log-likelihood function with asymptotic X^2 is derived. The confidence regions for the coefficients are constructed. Some simulation results indicate that the method performs better than the normal approximation method in term of coverage accuracies.
文摘In this paper, based on random left truncated and right censored data, the authors derive strong representations of the cumulative hazard function estimator and the product-limit estimator of the survival function. which are valid up to a given order statistic of the observations. A precise bound for the errors is obtained which only depends on the index of the last order statistic to be included.
文摘This paper aims to explore the application of Extreme Value Theory (EVT) in estimating the conditional extreme quantile for time-to-event outcomes by examining the functional relationship between ambulatory blood pressure trajectories and clinical outcomes in stroke patients. The study utilizes EVT to analyze the functional connection between ambulatory blood pressure trajectories and clinical outcomes in a sample of 297 stroke patients. The 24-hour ambulatory blood pressure measurement curves for every 15 minutes are considered, acknowledging a censored rate of 40%. The findings reveal that the sample mean excess function exhibits a positive gradient above a specific threshold, confirming the heavy-tailed distribution of data in stroke patients with a positive extreme value index. Consequently, the estimated conditional extreme quantile indicates that stroke patients with higher blood pressure measurements face an elevated risk of recurrent stroke occurrence at an early stage. This research contributes to the understanding of the relationship between ambulatory blood pressure and recurrent stroke, providing valuable insights for clinical considerations and potential interventions in stroke management.
文摘Based on left truncated and right censored dependent data, the estimators of higher derivatives of density function and hazard rate function are given by kernel smoothing method. When observed data exhibit α-mixing dependence, local properties including strong consistency and law of iterated logarithm are presented. Moreover, when the mode estimator is defined as the random variable that maximizes the kernel density estimator, the asymptotic normality of the mode estimator is established.
基金Supported by National Social Science Foundation of China (Grant No. 11CTJ004)National Natural Science Foundation of China (Grant Nos. 11171012 and 11101452)+3 种基金National Natural Science Foundation of Beijing (Grant No. 1102008)Natural Science Foundation Project of CQ CSTC (Grant No. cstcjjA00014)Research Foundation of Chongqing Municipal Education Commission (Grant No. KJ110720)Natural Science Foundation of Guangxi (Grant No. 2010GXNSFB013051)
文摘Empirical-likelihood-based inference for the parameters in a partially linear single-index model with randomly censored data is investigated. We introduce an estimated empirical likelihood for the parameters using a synthetic data approach and show that its limiting distribution is a mixture of central chi-squared distribution. To attack this difficulty we propose an adjusted empirical likelihood to achieve the standard X2-1imit. Furthermore, since the index is of norm 1, we use this constraint to reduce the dimension of parameters, which increases the accuracy of the confidence regions. A simulation study is carried out to compare its finite-sample properties with the existing method. An application to a real data set is illustrated.
基金Supported by the National Natural Science Foundation of China (No.10471140)
文摘In this paper an asymptotic distribution is obtained for the maximaldeviation between the kernel quantile density estimator and the quantile density when the data aresubject to random left truncation and right censorship. Based on this result we propose a fullysequential procedure for constructing a fixed-width confidence band for the quantile density on afinite interval and show that the procedure has the desired coverage probability asymptotically asthe width of the band approaches zero.
基金Partially supported by the National Natural Science Foundation of China (No.10071092).
文摘Abstract In this paper we consider a fixed design model in which the observations are subject to left truncation and right censoring. A generalized product-limit estimator for the conditional distribution at a given covariate value is proposed, and an almost sure asymptotic representation of this estimator is established. We also obtain the rate of uniform consistency, weak convergence and a modulus of continuity for this estimator. Applications include trimmed mean and quantile function estimators.These applications demonstrate the usefulness of the new matrix products.
文摘In this paper, we give a detailed description of the local behavior of theLipschitz-1/2 modulus for cumulative hazard process and PL-process when the data are subject to lefttruncation and right censored observations. We establish laws of the iterated logarithm of theLipschitz-1/2 modulus of PL-process and cumulative hazard process. These results for the PL-processare sharper than other results found in the literature, which can be used to establish theasymptotic properties of many statistics.
基金Supported by the National Natural Science Foundation of China (11071022)the Key Project of Hubei Provincial Department of Education (D20092207)
文摘Consider a semiparametric regression model Y_i=X_iβ+g(t_i)+e_i, 1 ≤ i ≤ n, where Y_i is censored on the right by another random variable C_i with known or unknown distribution G. The wavelet estimators of parameter and nonparametric part are given by the wavelet smoothing and the synthetic data methods. Under general conditions, the asymptotic normality for the wavelet estimators and the convergence rates for the wavelet estimators of nonparametric components are investigated. A numerical example is given.
基金partially supported by National Natural Science Foundation of China (NSFC) (No.70911130018,No.71271128)National Natural Science Funds for Distinguished Young Scholar (No.70825004)+1 种基金Creative Research Groups of China (No.10721101)Shanghai University of Finance and Economics through Project 211Phase III and Shanghai Leading Academic Discipline Project, Project Number: B803
文摘Receiver operating characteristic (ROC) curves are often used to study the two sample problem in medical studies. However, most data in medical studies are censored. Usually a natural estimator is based on the Kaplan-Meier estimator. In this paper we propose a smoothed estimator based on kernel techniques for the ROC curve with censored data. The large sample properties of the smoothed estimator are established. Moreover, deficiency is considered in order to compare the proposed smoothed estimator of the ROC curve with the empirical one based on Kaplan-Meier estimator. It is shown that the smoothed estimator outperforms the direct empirical estimator based on the Kaplan-Meier estimator under the criterion of deficiency. A simulation study is also conducted and a real data is analyzed.
基金Supported by the National Natural Science Foundation of China(Grant Nos.11771431,11690015,11926341,11901128 and 11601097)Key Laboratory of RCSDS,CAS(Grant Nos.2008DP 173182)Natural Science Foundation of Guangdong Province of China(Grant No.2018A030310068)。
文摘In some situations,the failure time of interest is defined as the gap time between two related events and the observations on both event times can suffer either right or interval censoring.Such data are usually referred to as doubly censored data and frequently encountered in many clinical and observational studies.Additionally,there may also exist a cured subgroup in the whole population,which means that not every individual under study will experience the failure time of interest eventually.In this paper,we consider regression analysis of doubly censored data with a cured subgroup under a wide class of flexible transformation cure models.Specifically,we consider marginal likelihood estimation and develop a two-step approach by combining the multiple imputation and a new expectation-maximization(EM)algorithm for its implementation.The resulting estimators are shown to be consistent and asymptotically normal.The finite sample performance of the proposed method is investigated through simulation studies.The proposed method is also applied to a real dataset arising from an AIDS cohort study for illustration.
基金supported by the State Key Program of National Natural Science Foundation of China(No.71331006)by the Graduate Innovation Foundation of Shanghai University of Finance and Economics of China(No.CXJJ-2018-408)。
文摘Published auxiliary information can be helpful in conducting statistical inference in a new study.In this paper,we synthesize the auxiliary information with semiparametric likelihood-based inference for censoring data with the total sample size is available.We express the auxiliary information as constraints on the regression coefficients and the covariate distribution,then use empirical likelihood method for general estimating equations to improve the efficiency of the interested parameters in the specified model.The consistency and asymptotic normality of the resulting regression parameter estimators established.Also numerical simulation and application with different supposed conditions show that the proposed method yields a substantial gain in efficiency of the interested parameters.
文摘A kernel density estimator is proposed when tile data are subject to censorship in multivariate case. The asymptotic normality, strong convergence and asymptotic optimal bandwidth which minimize the mean square error of the estimator are studied.
基金Supported by the National Natural Science Foundation of China(No.11171230,11231010)
文摘The maximum entropy method has been widely used in many fields, such as statistical mechanics,economics, etc. Its crucial idea is that when we make inference based on partial information, we must use the distribution with maximum entropy subject to whatever is known. In this paper, we investigate the empirical entropy method for right censored data and use simulation to compare the empirical entropy method with the empirical likelihood method. Simulations indicate that the empirical entropy method gives better coverage probability than that of the empirical likelihood method for contaminated and censored lifetime data.
文摘In survival analysis, the Kaplan-Meter estimator plays a very important role, and its asymptotic properties have been studied by many authors. In recefit years, people find that someimportant statistics can be expressed as the integrals with respect to it. In this paper we shalldiscuss the asymptotic behavior of such integrals. The strong convergence rste shall be givenand the weak convergence result in space D shall be proved.
文摘In this work,we consider the problem of estimating the parameters and predicting the unobserved or removed ordered data for the progressive type II censored flexible Weibull sample.Frequentist and Bayesian analyses are adopted for conducting the estimation and prediction problems.The likelihood method as well as the Bayesian sampling techniques is applied for the inference problems.The point predictors and credible intervals of unobserved data based on an informative set of data are computed.Markov ChainMonte Carlo samples are performed to compare the so-obtained methods,and one real data set is analyzed for illustrative purposes.