Study on Prevention and Treatment of Autophagy and Cervical HPV Infection by Traditional Chinese Medicine Based on Pathogenesis of "Syndrome of Dampness-heat Diffusing Downward"

Autophagy is a self-protection mechanism of the body,and also an important physiological process for cells to maintain internal environment stability.Studies have shown that the degree of autophagy damage is positively correlated with the expression of oncogenes,and the expression of oncogenes is closely related to cervical HPV infection,so the control of autophagy ability can interfere with cervical HPV virus infection.Traditional Chinese medicine believes that dampness-heat evil down,can damage and Chong Ren cell.The author believes that autophagy damage and the theory of dampness-heat injection in cervical HPV infection have similar pathogenic mechanism,and explores the prevention and treatment of autophagy and cervical HPV infection based on the theory of traditional Chinese medicine dampness-heat injection,in attempt to provide a new treatment for clinical prevention and treatment.

The Changes in the Awareness of Cervical Cancer Prevention and the Acceptability of HPV Vaccines among Women after Their Introduction in China

Cervical cancer is a form of malignant tumor that seriously threatens women’s health. In China,according to the cancer statistics, 98,900 new cervical cancer cases and 30,500 deaths due to cervical cancer were estimated to have occurred in2015, and the incidence and mortality rates still exhibited an upward trend[1].

Social innovation in diagnostics:three case studies

Background:Diagnostics are essential for identifying and controlling diseases.However,limited access to diagnostics hinders public health efforts in many settings.Social innovation may provide a framework for expanding access to diagnostics in the global south.Here social innovation is defined as implementing a known public health tool via a novel,community-driven technique.Main Body:In this article,we discuss three diverse cases that show the potential for using social innovation in diagnostics.The cases chosen for inclusion here demonstrate the importance of social innovation in diagnostics across different geographic,cultural,and health system contexts.They include malaria testing via schools in Malawi,cervical human papillomavirus(HPV)sample self-collection in Peru,and crowdsourcing human immunodeficiency virus(HIV)testing in China.For each case,we present the public health problem and the impact of using social innovation to increase accessibility of diagnostics.We discuss implications of each diagnostic approach and the importance of social innovation in creating these potential solutions.We argue that social innovation is useful in improving the delivery of essential diagnostic tools in low-and middle-income countries.Conclusions:Interventions in Malawi,Peru,and China suggest social innovation increases uptake of diagnostics.The same tools and principles utilized in these cases can be adapted for use in other contexts.Such diagnostic innovations may help improve identification of and linkage to care for many diseases.The approach presents a unique opportunity to better address public health issues and increase accessibility in LMIC health systems.