The main high points ofthis tour are sightseeing inthe Maling River Valley, riftvalley drifting, a visit to theBouyei village, and theGuizhou Wedding CustomsMuseum.
In laser-guided bomb attacking process,the target indication from the laser target designator is the premise for the bomb to hit the target accurately.Considering the lack of quantitative study of the irradiation area...In laser-guided bomb attacking process,the target indication from the laser target designator is the premise for the bomb to hit the target accurately.Considering the lack of quantitative study of the irradiation area of the laser target designator,this paper,based on the existing aircraft motion model and the laser transmission model,uses two aircraft as respectively the carrier of the laser-guided bomb and the carrier of the laser designator and proposes a method to calculate the global irradiation area of the airborne laser designator.By using the proposed algorithm,the global irradiation area when attacking a large flat target or a large spherical target is simulated respectively.Finally,according to the simulation results,the influences of different factors on the shapes of the irradiation area are discussed in detail.展开更多
Objective： To investigate the effect of Huogu II Formula （活骨 II方 ） with medicinal guide Radix Achyranthis Bidentatae （Ach） on bone marrow stem cells （BMSCs） homing to necrosis area after osteonecrosis of the...Objective： To investigate the effect of Huogu II Formula （活骨 II方 ） with medicinal guide Radix Achyranthis Bidentatae （Ach） on bone marrow stem cells （BMSCs） homing to necrosis area after osteonecrosis of the femoral head （ONFH） frozen by liquid nitrogen in rabbit as well as to explore the mechanism of prevention and treatment for ONFH. Methods： The animal model of ONFH was established by liquid nitrogen frozen on the rabbit left hind leg. Forty-eight Japanese White rabbits were randomly assigned to sham-operated group, model group, Huogu II group, and Huogu II plus Ach group, with 12 rabbits in each. During the course of ONFH animal model establishment, all rabbits were subcutaneously injected with recombinant human granulocyte colony-stimulating factor [rhG-CSF, 30 μg/（kg.day） for continuous 7 days]. Meanwhile, normal saline and decoction of the two formulae were administrated by gavage, respectively. White blood cells （WBC） were counted in peripheral blood before and after injection of rhG-CSF. Materials were drawn on the 2rid and 4th weeks after model built; bone glutamine protein （BGP） and bone morphogenetic protein 2 （BMP2） levels in serum were tested. Histopathologic changes were observed by hematoxylin and eosin （HE） staining. BMP2 mRNA levels were detected with in situ hybridization （iSH） staining. 5-Bromo-2＇-deoxyuridine （BrdU） and stromal cell derived factor 1 （SDF-1） were measured by immunohistochemical assay in femoral head of the left hind leg. Results： Compared with the shamoperated group, the ratio of empty lacuna, serum BGP, and SDF-1 level in the model group increased significantly, and BMP2 in both serum and femoral head decreased significantly. However, in comparison with the model group, the empty lacuna ratio of Huogu II group and Huogu II plus Ach group decreased obviously in addition to the levels of serum BGP and BMP2, and the expressions of BMP2 mRNA, BrdU, and SDF-1 increased significantly. Above changes were particularly obvious in Huogu II plus Ach group. BGP and SDF-1 on the 2nd week and empty lacuna rate and serum BMP2 level on the 4th week in Huogu II group significantly exceeded their counterparts. On the 2nd week, only in Huogu II plus Ach group that the BrdU counting rose significantly. On the 4th week, empty lacuna rate and serum BMP2 level in Huogu II plus Ach group exceeded those in Huogu II group distinctively. Conclusions： To a certain extent, the medicinal guide Ach improves the preventive and therapeutic effects of Huogu II Formula on expedmental ONFH model. The possible mechanism of this is related to its promoting effect on directional homing of BMSCs to the necrosis area.展开更多
目的研究胃超声结合身体质量指数(body mass index,BMI)用于指导行全麻剖宫产术术前禁食水时间的可行性。方法回顾性分析2012年1月—2022年12月在长春市妇幼保健院行全麻剖宫产术的450例孕产妇。根据孕产妇BMI增幅(△BMI)将其分为3组,A...目的研究胃超声结合身体质量指数(body mass index,BMI)用于指导行全麻剖宫产术术前禁食水时间的可行性。方法回顾性分析2012年1月—2022年12月在长春市妇幼保健院行全麻剖宫产术的450例孕产妇。根据孕产妇BMI增幅(△BMI)将其分为3组,A组△BMI<4 kg/m^(2),B组24 kg/m≤△BMI≤6 kg/m^(2),C组△BMI>6 kg/m^(2)。食用相同食物,比较3组胃排空能力及预后。结果A组禁食水时间为(6.85±1.53)h,B组禁食水时间为(7.49±1.46)h,C组禁食水时间为(7.84±1.24)h,3组禁食水时间比较,差异有统计学意义(P<0.05);3组Ⅱ、Ⅲ期及产前T1、T3、T4各时间点胃窦横截面积(cross-sectional area,CSA)比较,差异有统计学意义(P<0.05);3组妊娠结局[巨大儿、转入新生儿重症监护室(neonatal intensive care unit,NICU)、新生儿窒息]及口渴、饥饿感评分比较,差异有统计学意义(P<0.05);C组首次排气时间长于A组、B组,满意度评分低于A组与B组(P<0.05)。结论超声引导下胃窦部CSA可更精准地判定产妇的胃内容量,从而预判术前禁食水时间,改善妊娠结局。展开更多
文摘The main high points ofthis tour are sightseeing inthe Maling River Valley, riftvalley drifting, a visit to theBouyei village, and theGuizhou Wedding CustomsMuseum.
基金supported by the Aeronautical Science Foundation of China(ASFC-20135153031ASFC-20135553035ASFC-2017ZC53033)
文摘In laser-guided bomb attacking process,the target indication from the laser target designator is the premise for the bomb to hit the target accurately.Considering the lack of quantitative study of the irradiation area of the laser target designator,this paper,based on the existing aircraft motion model and the laser transmission model,uses two aircraft as respectively the carrier of the laser-guided bomb and the carrier of the laser designator and proposes a method to calculate the global irradiation area of the airborne laser designator.By using the proposed algorithm,the global irradiation area when attacking a large flat target or a large spherical target is simulated respectively.Finally,according to the simulation results,the influences of different factors on the shapes of the irradiation area are discussed in detail.
基金Supported by the National Natural Science Foundation of China (No.30672770)
文摘Objective： To investigate the effect of Huogu II Formula （活骨 II方 ） with medicinal guide Radix Achyranthis Bidentatae （Ach） on bone marrow stem cells （BMSCs） homing to necrosis area after osteonecrosis of the femoral head （ONFH） frozen by liquid nitrogen in rabbit as well as to explore the mechanism of prevention and treatment for ONFH. Methods： The animal model of ONFH was established by liquid nitrogen frozen on the rabbit left hind leg. Forty-eight Japanese White rabbits were randomly assigned to sham-operated group, model group, Huogu II group, and Huogu II plus Ach group, with 12 rabbits in each. During the course of ONFH animal model establishment, all rabbits were subcutaneously injected with recombinant human granulocyte colony-stimulating factor [rhG-CSF, 30 μg/（kg.day） for continuous 7 days]. Meanwhile, normal saline and decoction of the two formulae were administrated by gavage, respectively. White blood cells （WBC） were counted in peripheral blood before and after injection of rhG-CSF. Materials were drawn on the 2rid and 4th weeks after model built; bone glutamine protein （BGP） and bone morphogenetic protein 2 （BMP2） levels in serum were tested. Histopathologic changes were observed by hematoxylin and eosin （HE） staining. BMP2 mRNA levels were detected with in situ hybridization （iSH） staining. 5-Bromo-2＇-deoxyuridine （BrdU） and stromal cell derived factor 1 （SDF-1） were measured by immunohistochemical assay in femoral head of the left hind leg. Results： Compared with the shamoperated group, the ratio of empty lacuna, serum BGP, and SDF-1 level in the model group increased significantly, and BMP2 in both serum and femoral head decreased significantly. However, in comparison with the model group, the empty lacuna ratio of Huogu II group and Huogu II plus Ach group decreased obviously in addition to the levels of serum BGP and BMP2, and the expressions of BMP2 mRNA, BrdU, and SDF-1 increased significantly. Above changes were particularly obvious in Huogu II plus Ach group. BGP and SDF-1 on the 2nd week and empty lacuna rate and serum BMP2 level on the 4th week in Huogu II group significantly exceeded their counterparts. On the 2nd week, only in Huogu II plus Ach group that the BrdU counting rose significantly. On the 4th week, empty lacuna rate and serum BMP2 level in Huogu II plus Ach group exceeded those in Huogu II group distinctively. Conclusions： To a certain extent, the medicinal guide Ach improves the preventive and therapeutic effects of Huogu II Formula on expedmental ONFH model. The possible mechanism of this is related to its promoting effect on directional homing of BMSCs to the necrosis area.
