With the appearance of novel radar signal with low intercept probability, the bandwidth of radar receiver is wider and wider. Wideband digital receiver becomes a research hotspot in the field of communication...With the appearance of novel radar signal with low intercept probability, the bandwidth of radar receiver is wider and wider. Wideband digital receiver becomes a research hotspot in the field of communication, radar and electronic reconnaissance, etc. As one of wideband digital receiver systems, digital channelized receiver has become a research emphasis due to the characteristics of full probability receiving and processing multiple signals. Digital channelized technology and signal sampling theory are deeply studied and an efficient channelized model is derived based on filter banks. The correctness of the model is verified by computer simulation The model has less computation compared with the traditional model, which is suitable for engineering application展开更多
The data on the hillslope and channelized debris flows in the Shitou area of central Taiwan occurred during Typhoons Toraji and Nali in 2001 were applied in this paper. The geomorphic parameters, including the flow le...The data on the hillslope and channelized debris flows in the Shitou area of central Taiwan occurred during Typhoons Toraji and Nali in 2001 were applied in this paper. The geomorphic parameters, including the flow length, gully gradient, drainage area and form factor of the debris flows were determined by spatial analysis using a Geographic Information System (GIS) based on the data derived from field investigation, aerial photographs, and topographical maps. According to such determined geomorphic parameters, the threshold conditions and empirical equations, such as the relationship between the gully gradient and drainage area and that between gully length and drainage area and topographic parameter, are presented and used to distinguish the geomorphic characteristics between the channelized and hillslope debris flows.展开更多
An approach is proposed to realize a digital channelized receiver in the fractional Fourier domain (FRFD) for signal intercept applications. The presented architecture can be considered as a generalization of that i...An approach is proposed to realize a digital channelized receiver in the fractional Fourier domain (FRFD) for signal intercept applications. The presented architecture can be considered as a generalization of that in the traditional Fourier domain. Since the linear frequency modulation (LFM) signal has a good energy concentration in the FRFD, by choosing an appropriate fractional Fourier transform (FRFT) order, the presented architecture can concentrate the broadband LFM signal into only one sub-channel and that will prevent it from crossing several sub-channels. Thus the performance of the signal detection and parameter estimation after the sub-channel output will be improved significantly. The computational complexity is reduced enormously due to the implementation of the polyphase filter bank decomposition, thus the proposed architecture can be realized as efficiently as in the Fourier domain. The related simulation results are presented to verify the validity of the theories and methods involved in this paper.展开更多
For digital channelized frequency division multiple access based satellite communication(SATCOM) systems,it is a challenging but critical issue to improve the transponder power and spectrum efficiency simultaneously u...For digital channelized frequency division multiple access based satellite communication(SATCOM) systems,it is a challenging but critical issue to improve the transponder power and spectrum efficiency simultaneously under limited and non-linear high-power amplifier conditions.In this paper,different from the traditional link supportability designs aiming at minimizing the total transponder output power,a maximal sum Shannon capacity optimization objective is firstly raised subject to link supportability constraints.Furthermore,an efficient multilevel optimization(MO) algorithm is proposed to solve the considered optimization problem in the case of single link for each terminal.Moreover,in the case of multiple links for one terminal,an improved MO algorithm involving Golden section and discrete gradient searching procedures is proposed to optimize power allocation over all links.Finally,several numerical results are provided to demonstrate the effectiveness of our proposals.Comparison results show that,by the MO algorithm,not only all links' supportability can be guaranteed but also a larger sum capacity can be achieved with lower complexity.展开更多
A novel efficient partial sharing channelization structure with odd and even stacking is designed and implemented. There are two special designs in the proposed structure. Firstly, by the intensive channel overlap des...A novel efficient partial sharing channelization structure with odd and even stacking is designed and implemented. There are two special designs in the proposed structure. Firstly, by the intensive channel overlap design, for non-cooperative wideband signals, the proposed structure can achieve good parameter estimation accuracy and high probability of complete interception.Secondly, based on the partial sharing design developed in this paper, the computation burden of the proposed structure can be greatly reduced compared with the traditional directly implemented structures. Experiments and numerical simulations are conducted to evaluate the proposed structure, which shows its improvements over traditional methods in terms of field programmable gate arrays(FPGA) resource consumption and parameter estimation accuracy.展开更多
Assessing environmental flows (e-flows) for urban rivers is important for water resources planning and river protection, Many e-flow assessment methods have been established based on species' habitat pro- vision re...Assessing environmental flows (e-flows) for urban rivers is important for water resources planning and river protection, Many e-flow assessment methods have been established based on species' habitat pro- vision requirements and pollutant dilution requirements, To avoid flood risk, however, many urban rivers have been transformed into straight, trapezoidal-profiled concrete channels, leading to the disappearance of valuable species, With the construction of water pollution-control projects, pollutant inputs into rivers have been effectively controlled in some urban rivers, For these rivers, the e-flows determined by tradi- tional methods will be very small, and will consequently lead to a low priority being given to river pro- tection in future water resources allocation and management, To more effectively assess the e-flows of channelized urban rivers, we propose three e-flow degrees, according to longitudinal hydrological con- nectivity (high, medium, and low), in addition to the pollutant dilution water requirement determined by the mass-balance equation, In the high connectivity scenario, the intent is for the e-flows to maintain flow velocity, which can ensure the self-purification of rivers and reduce algal blooms; in the medium connectivity scenario, the intent is for the e-flows to permanently maintain the longitudinal hydrological connectivity of rivers that are isolated into several ponds by means of weirs, in order to ensure the exchange of material, energy, and information in rivers; and in the low connectivity scenario, the intent is for the e-flows to intermittently connect isolated ponds every few days (which is designed to further reduce e-flows), The proposed methods have been used in Shiwuli River, China, to demonstrate their effectiveness, The new methods can offer more precise and realistic e-flow results and can effectively direct the construction and management of e-flow supply projects,展开更多
Most inverse reservoir modeling techniques require many forward simulations, and the posterior models cannot preserve geological features of prior models. This study proposes an iterative static modeling approach that...Most inverse reservoir modeling techniques require many forward simulations, and the posterior models cannot preserve geological features of prior models. This study proposes an iterative static modeling approach that utilizes dynamic data for rejecting an unsuitable training image(TI) among a set of TI candidates and for synthesizing history-matched pseudo-soft data. The proposed method is applied to two cases of channelized reservoirs, which have uncertainty in channel geometry such as direction, amplitude, and width. Distance-based clustering is applied to the initial models in total to select the qualified models efficiently. The mean of the qualified models is employed as a history-matched facies probability map in the next iteration of static models. Also, the most plausible TI is determined among TI candidates by rejecting other TIs during the iteration. The posterior models of the proposed method outperform updated models of ensemble Kalman filter(EnKF) and ensemble smoother(ES) because they describe the true facies connectivity with bimodal distribution and predict oil and water production with a reasonable range of uncertainty. In terms of simulation time, it requires 30 times of forward simulation in history matching, while the EnKF and ES need 9000 times and 200 times, respectively.展开更多
Granular mass flows (e.g., debris flows/avalanches) in landslide-prone areas are of great concern because they often cause catastrophic disasters as a result of their long run-out distances and large impact forces. ...Granular mass flows (e.g., debris flows/avalanches) in landslide-prone areas are of great concern because they often cause catastrophic disasters as a result of their long run-out distances and large impact forces. To investigate the factors influencing granular mass flow mobility, experimental tests were conducted in a flume model. Granular materials consisting of homogeneous sand and non- homogeneous sandy soil were used for studying particle size effects. Run-out tests with variable flow masses, water contents, and sloping channel confinement parameters were conducted as well. The results indicated that granular mass flow mobility was significantly influenced by the initial water content; a critical water content corresponding to the smallest flow mobility exists for different granular materials. An increase in the total flow mass generally induced a reduction in the travel angle (an increase in flow mobility). Consistent with field observations, the travel angles for different granular materials decreased roughly in proportion to the logarithm of mass. The flume model tests illustrate that the measured travel angles increase as the proportion of fine particles increases. Interestingly, natural terrain possesses critical confinement characteristics for different granular mass flows.展开更多
Riparian zones of channelized agricultural streams in northwestern Mississippi typically consist of narrow vegetative corridors low in habitat diversity and lacking riparian wetlands. Land clearing practices and strea...Riparian zones of channelized agricultural streams in northwestern Mississippi typically consist of narrow vegetative corridors low in habitat diversity and lacking riparian wetlands. Land clearing practices and stream channelization have led to the development of gully erosion and further fragmentation of these degraded riparian zones. Currently, installation of a gully erosion control structure (drop pipe) at the riparian zone-agricultural field interface leads to the incidental establishment of four riparian habitat types that differ in habitat area, vegetative structure, and pool size. Small mammals were sampled within four sites of each habitat type from June 1994 to July 1995. Small mammal diversity, abundance, and hispid cotton rat (Sigmodon hispidus) weight were the least within smallest Type I habitats with the least vegetative structural diversity and were the greatest within the larger Type II, III, or IV habitats having greater vegetative structural diversity and pool size. Small mammal diversity and abundance were the least in the summer 1994, increased in the fall 1994, and then declined later in our study. Hispid cotton rat abundance was the least in summer 1994, winter 1994, and spring 1995 and was the greatest in fall 1994 and summer 1995. Our results suggest that modifying the drop pipe installation design to facilitate the development of larger riparian habitats with greater vegetative structural diversity will provide the greatest benefits for small mammals.展开更多
A structure of dynamic reconfigurable channelized filter bank is proposed in order to solve the problem that the uniform channelized receiver cannot receive the cross-channel and wideband signal. The dynamic reconfigu...A structure of dynamic reconfigurable channelized filter bank is proposed in order to solve the problem that the uniform channelized receiver cannot receive the cross-channel and wideband signal. The dynamic reconfigurable channelized filter bank is divided into two parts-the analysis filter bank and the synthesis filter bank. The function of the analysis filter bank is to divide the received signal into several sub-signals according to the channel division. Then the sub-signals of each channel need to be detected and discriminated. At last, we use the sub-signals to reconstruct the original received signal by the synthesis filter bank. The analysis filter and the synthesis filter bank of the dynamic reconfigurable channelized filter bank are all efficient polyphase structures, so it can save more hardware resources and has extensive applicability. The structure is simulated by MATLAB and the simulation results verify the correctness of this structure.展开更多
The concentration difference in the near-surface region of lithium metal is the main cause of lithium dendrite growth.Resolving this issue will be key to achieving high-performance lithium metal batteries(LMBs).Herein...The concentration difference in the near-surface region of lithium metal is the main cause of lithium dendrite growth.Resolving this issue will be key to achieving high-performance lithium metal batteries(LMBs).Herein,we construct a lithium nitrate(LiNO_(3))-implanted electroactiveβphase polyvinylidene fluoride-co-hexafluoropropylene(PVDF-HFP)crystalline polymorph layer(PHL).The electronegatively charged polymer chains attain lithium ions on the surface to form lithium-ion charged channels.These channels act as reservoirs to sustainably release Li ions to recompense the ionic flux of electrolytes,decreasing the growth of lithium dendrites.The stretched molecular channels can also accelerate the transport of Li ions.The combined effects enable a high Coulombic efficiency of 97.0%for 250 cycles in lithium(Li)||copper(Cu)cell and a stable symmetric plating/stripping behavior over 2000 h at 3 mA cm^(-2)with ultrahigh Li utilization of 50%.Furthermore,the full cell coupled with PHL-Cu@Li anode and Li Fe PO_(4) cathode exhibits long-term cycle stability with high-capacity retention of 95.9%after 900 cycles.Impressively,the full cell paired with LiNi_(0.87)Co_(0.1)Mn_(0.03)O_(2)maintains a discharge capacity of 170.0 mAh g^(-1)with a capacity retention of 84.3%after 100 cycles even under harsh condition of ultralow N/P ratio of 0.83.This facile strategy will widen the potential application of LiNO_(3)in ester-based electrolyte for practical high-voltage LMBs.展开更多
Na^(+)/K^(+)-ATPase is a transmembrane protein that has important roles in the maintenance of electrochemical gradients across cell membranes by transporting three Na^(+)out of and two K^(+)into cells.Additionally,Na^...Na^(+)/K^(+)-ATPase is a transmembrane protein that has important roles in the maintenance of electrochemical gradients across cell membranes by transporting three Na^(+)out of and two K^(+)into cells.Additionally,Na^(+)/K^(+)-ATPase participates in Ca^(2+)-signaling transduction and neurotransmitter release by coordinating the ion concentration gradient across the cell membrane.Na^(+)/K^(+)-ATPase works synergistically with multiple ion channels in the cell membrane to form a dynamic network of ion homeostatic regulation and affects cellular communication by regulating chemical signals and the ion balance among different types of cells.Therefo re,it is not surprising that Na^(+)/K^(+)-ATPase dysfunction has emerged as a risk factor for a variety of neurological diseases.However,published studies have so far only elucidated the important roles of Na^(+)/K^(+)-ATPase dysfunction in disease development,and we are lacking detailed mechanisms to clarify how Na^(+)/K^(+)-ATPase affects cell function.Our recent studies revealed that membrane loss of Na^(+)/K^(+)-ATPase is a key mechanism in many neurological disorders,particularly stroke and Parkinson's disease.Stabilization of plasma membrane Na^(+)/K^(+)-ATPase with an antibody is a novel strategy to treat these diseases.For this reason,Na^(+)/K^(+)-ATPase acts not only as a simple ion pump but also as a sensor/regulator or cytoprotective protein,participating in signal transduction such as neuronal autophagy and apoptosis,and glial cell migration.Thus,the present review attempts to summarize the novel biological functions of Na^(+)/K^(+)-ATPase and Na^(+)/K^(+)-ATPase-related pathogenesis.The potential for novel strategies to treat Na^(+)/K^(+)-ATPase-related brain diseases will also be discussed.展开更多
To date,several molecules have been found to facilitate iron influx,while the types of iron influx channels remain to be elucidated.Here,Piezo1 channel was identified as a key iron transporter in response to mechanica...To date,several molecules have been found to facilitate iron influx,while the types of iron influx channels remain to be elucidated.Here,Piezo1 channel was identified as a key iron transporter in response to mechanical stress.Piezo1-mediated iron overload disturbed iron metabolism and exaggerated ferroptosis in nucleus pulposus cells(NPCs).Importantly,Piezo1-induced iron influx was independent of the transferrin receptor(TFRC),a well-recognized iron gatekeeper.Furthermore,pharmacological inactivation of Piezo1 profoundly reduced iron accumulation,alleviated mitochondrial ROS,and suppressed ferroptotic alterations in stimulation of mechanical stress.Moreover,conditional knockout of Piezo1(Col2a1-CreERT Piezo1^(flox/flox))attenuated the mechanical injury-induced intervertebral disc degeneration(IVDD).Notably,the protective effect of Piezo1 deficiency in IVDD was dampened in Piezo1/Gpx4 conditional double knockout(cDKO)mice(Col2a1-CreERT Piezo1^(flox/flox)/Gpx4^(flox/flox)).These findings suggest that Piezo1 is a potential determinant of iron influx,indicating that the Piezo1-iron-ferroptosis axis might shed light on the treatment of mechanical stress-induced diseases.展开更多
Identification of the ice channel is the basic technology for developing intelligent ships in ice-covered waters,which is important to ensure the safety and economy of navigation.In the Arctic,merchant ships with low ...Identification of the ice channel is the basic technology for developing intelligent ships in ice-covered waters,which is important to ensure the safety and economy of navigation.In the Arctic,merchant ships with low ice class often navigate in channels opened up by icebreakers.Navigation in the ice channel often depends on good maneuverability skills and abundant experience from the captain to a large extent.The ship may get stuck if steered into ice fields off the channel.Under this circumstance,it is very important to study how to identify the boundary lines of ice channels with a reliable method.In this paper,a two-staged ice channel identification method is developed based on image segmentation and corner point regression.The first stage employs the image segmentation method to extract channel regions.In the second stage,an intelligent corner regression network is proposed to extract the channel boundary lines from the channel region.A non-intelligent angle-based filtering and clustering method is proposed and compared with corner point regression network.The training and evaluation of the segmentation method and corner regression network are carried out on the synthetic and real ice channel dataset.The evaluation results show that the accuracy of the method using the corner point regression network in the second stage is achieved as high as 73.33%on the synthetic ice channel dataset and 70.66%on the real ice channel dataset,and the processing speed can reach up to 14.58frames per second.展开更多
Low Earth Orbit(LEO)multibeam satellites will be widely used in the next generation of satellite communication systems,whose inter-beam interference will inevitably limit the performance of the whole system.Nonlinear ...Low Earth Orbit(LEO)multibeam satellites will be widely used in the next generation of satellite communication systems,whose inter-beam interference will inevitably limit the performance of the whole system.Nonlinear precoding such as Tomlinson-Harashima precoding(THP)algorithm has been proved to be a promising technology to solve this problem,which has smaller noise amplification effect compared with linear precoding.However,the similarity of different user channels(defined as channel correlation)will degrade the performance of THP algorithm.In this paper,we qualitatively analyze the inter-beam interference in the whole process of LEO satellite over a specific coverage area,and the impact of channel correlation on Signal-to-Noise Ratio(SNR)of receivers when THP is applied.One user grouping algorithm is proposed based on the analysis of channel correlation,which could decrease the number of users with high channel correlation in each precoding group,thus improve the performance of THP.Furthermore,our algorithm is designed under the premise of co-frequency deployment and orthogonal frequency division multiplexing(OFDM),which leads to more users under severe inter-beam interference compared to the existing research on geostationary orbit satellites broadcasting systems.Simulation results show that the proposed user grouping algorithm possesses higher channel capacity and better bit error rate(BER)performance in high SNR conditions relative to existing works.展开更多
The great potentials of massive Multiple-Input Multiple-Output(MIMO)in Frequency Division Duplex(FDD)mode can be fully exploited when the downlink Channel State Information(CSI)is available at base stations.However,th...The great potentials of massive Multiple-Input Multiple-Output(MIMO)in Frequency Division Duplex(FDD)mode can be fully exploited when the downlink Channel State Information(CSI)is available at base stations.However,the accurate CsI is difficult to obtain due to the large amount of feedback overhead caused by massive antennas.In this paper,we propose a deep learning based joint channel estimation and feedback framework,which comprehensively realizes the estimation,compression,and reconstruction of downlink channels in FDD massive MIMO systems.Two networks are constructed to perform estimation and feedback explicitly and implicitly.The explicit network adopts a multi-Signal-to-Noise-Ratios(SNRs)technique to obtain a single trained channel estimation subnet that works well with different SNRs and employs a deep residual network to reconstruct the channels,while the implicit network directly compresses pilots and sends them back to reduce network parameters.Quantization module is also designed to generate data-bearing bitstreams.Simulation results show that the two proposed networks exhibit excellent performance of reconstruction and are robust to different environments and quantization errors.展开更多
Due to the interdependency of frame synchronization(FS)and channel estimation(CE),joint FS and CE(JFSCE)schemes are proposed to enhance their functionalities and therefore boost the overall performance of wireless com...Due to the interdependency of frame synchronization(FS)and channel estimation(CE),joint FS and CE(JFSCE)schemes are proposed to enhance their functionalities and therefore boost the overall performance of wireless communication systems.Although traditional JFSCE schemes alleviate the influence between FS and CE,they show deficiencies in dealing with hardware imperfection(HI)and deterministic line-of-sight(LOS)path.To tackle this challenge,we proposed a cascaded ELM-based JFSCE to alleviate the influence of HI in the scenario of the Rician fading channel.Specifically,the conventional JFSCE method is first employed to extract the initial features,and thus forms the non-Neural Network(NN)solutions for FS and CE,respectively.Then,the ELMbased networks,named FS-NET and CE-NET,are cascaded to capture the NN solutions of FS and CE.Simulation and analysis results show that,compared with the conventional JFSCE methods,the proposed cascaded ELM-based JFSCE significantly reduces the error probability of FS and the normalized mean square error(NMSE)of CE,even against the impacts of parameter variations.展开更多
Transient receptor potential(TRP)channels are strongly associated with colon cancer development and progression.This study leveraged a multivariate Cox regression model on publicly available datasets to construct a TR...Transient receptor potential(TRP)channels are strongly associated with colon cancer development and progression.This study leveraged a multivariate Cox regression model on publicly available datasets to construct a TRP channels-associated gene signature,with further validation of signature in real world samples from our hospital treated patient samples.Kaplan-Meier(K-M)survival analysis and receiver operating characteristic(ROC)curves were employed to evaluate this gene signature’s predictive accuracy and robustness in both training and testing cohorts,respectively.Additionally,the study utilized the CIBERSORT algorithm and single-sample gene set enrichment analysis to explore the signature’s immune infiltration landscape and underlying functional implications.The support vector machine algorithm was applied to evaluate the signature’s potential in predicting chemotherapy outcomes.The findings unveiled a novel three TRP channels-related gene signature(MCOLN1,TRPM5,and TRPV4)in colon adenocarcinoma(COAD).The ROC and K-M survival curves in the training dataset(AUC=0.761;p=1.58e-05)and testing dataset(AUC=0.699;p=0.004)showed the signature’s robust predictive capability for the overall survival of COAD patients.Analysis of the immune infiltration landscape associated with the signature revealed higher immune infiltration,especially an increased presence of M2 macrophages,in high-risk group patients compared to their low-risk counterparts.High-risk score patients also exhibited potential responsiveness to immune checkpoint inhibitor therapy,evident through increased CD86 and PD-1 expression profiles.Moreover,the TRPM5 gene within the signature was highly expressed in the chemoresistance group(p=0.00095)and associated with poor prognosis(p=0.036)in COAD patients,highlighting its role as a hub gene of chemoresistance.Ultimately,this signature emerged as an independent prognosis factor for COAD patients(p=6.48e-06)and expression of model gene are validated by public data and real-world patients.Overall,this bioinformatics study provides valuable insights into the prognostic implications and potential chemotherapy resistance mechanisms associated with TRPs-related genes in colon cancer.展开更多
Calcium influx into neurons triggers neuronal death during cerebral ischemia/reperfusion injury.Various calcium channels are involved in cerebral ischemia/reperfusion injury.Cav3.2 channel is a main subtype of T-type ...Calcium influx into neurons triggers neuronal death during cerebral ischemia/reperfusion injury.Various calcium channels are involved in cerebral ischemia/reperfusion injury.Cav3.2 channel is a main subtype of T-type calcium channels.T-type calcium channel blockers,such as pimozide and mibefradil,have been shown to prevent cerebral ischemia/reperfusion injury-induced brain injury.However,the role of Cav3.2 channels in cerebral ischemia/reperfusion injury remains unclear.Here,in vitro and in vivo models of cerebral ischemia/reperfusion injury were established using middle cerebral artery occlusion in mice and high glucose hypoxia/reoxygenation exposure in primary hippocampal neurons.The results showed that Cav3.2 expression was significantly upregulated in injured hippocampal tissue and primary hippocampal neurons.We further established a Cav3.2 gene-knockout mouse model of cerebral ischemia/reperfusion injury.Cav3.2 knockout markedly reduced infarct volume and brain water content,and alleviated neurological dysfunction after cerebral ischemia/reperfusion injury.Additionally,Cav3.2 knockout attenuated cerebral ischemia/reperfusion injury-induced oxidative stress,inflammatory response,and neuronal apoptosis.In the hippocampus of Cav3.2-knockout mice,calcineurin overexpression offset the beneficial effect of Cav3.2 knockout after cerebral ischemia/reperfusion injury.These findings suggest that the neuroprotective function of Cav3.2 knockout is mediated by calcineurin/nuclear factor of activated T cells 3 signaling.Findings from this study suggest that Cav3.2 could be a promising target for treatment of cerebral ischemia/reperfusion injury.展开更多
基金Natural Science Foundation of Inner Mongolia Autonomous Region of China(No.2013MS0916)Research Program of Science and Technology at Universities of Inner Mongolia Autonomous Region(No.NJZY237)
文摘With the appearance of novel radar signal with low intercept probability, the bandwidth of radar receiver is wider and wider. Wideband digital receiver becomes a research hotspot in the field of communication, radar and electronic reconnaissance, etc. As one of wideband digital receiver systems, digital channelized receiver has become a research emphasis due to the characteristics of full probability receiving and processing multiple signals. Digital channelized technology and signal sampling theory are deeply studied and an efficient channelized model is derived based on filter banks. The correctness of the model is verified by computer simulation The model has less computation compared with the traditional model, which is suitable for engineering application
文摘The data on the hillslope and channelized debris flows in the Shitou area of central Taiwan occurred during Typhoons Toraji and Nali in 2001 were applied in this paper. The geomorphic parameters, including the flow length, gully gradient, drainage area and form factor of the debris flows were determined by spatial analysis using a Geographic Information System (GIS) based on the data derived from field investigation, aerial photographs, and topographical maps. According to such determined geomorphic parameters, the threshold conditions and empirical equations, such as the relationship between the gully gradient and drainage area and that between gully length and drainage area and topographic parameter, are presented and used to distinguish the geomorphic characteristics between the channelized and hillslope debris flows.
基金supported by the Program for New Century Excellent Talents in University(NCET-06-0921)
文摘An approach is proposed to realize a digital channelized receiver in the fractional Fourier domain (FRFD) for signal intercept applications. The presented architecture can be considered as a generalization of that in the traditional Fourier domain. Since the linear frequency modulation (LFM) signal has a good energy concentration in the FRFD, by choosing an appropriate fractional Fourier transform (FRFT) order, the presented architecture can concentrate the broadband LFM signal into only one sub-channel and that will prevent it from crossing several sub-channels. Thus the performance of the signal detection and parameter estimation after the sub-channel output will be improved significantly. The computational complexity is reduced enormously due to the implementation of the polyphase filter bank decomposition, thus the proposed architecture can be realized as efficiently as in the Fourier domain. The related simulation results are presented to verify the validity of the theories and methods involved in this paper.
基金supportedin part by Natural Science Foundation under grant No.91338108,91438206Co-innovation Laboratory of Aerospace Broadband Network Technology
文摘For digital channelized frequency division multiple access based satellite communication(SATCOM) systems,it is a challenging but critical issue to improve the transponder power and spectrum efficiency simultaneously under limited and non-linear high-power amplifier conditions.In this paper,different from the traditional link supportability designs aiming at minimizing the total transponder output power,a maximal sum Shannon capacity optimization objective is firstly raised subject to link supportability constraints.Furthermore,an efficient multilevel optimization(MO) algorithm is proposed to solve the considered optimization problem in the case of single link for each terminal.Moreover,in the case of multiple links for one terminal,an improved MO algorithm involving Golden section and discrete gradient searching procedures is proposed to optimize power allocation over all links.Finally,several numerical results are provided to demonstrate the effectiveness of our proposals.Comparison results show that,by the MO algorithm,not only all links' supportability can be guaranteed but also a larger sum capacity can be achieved with lower complexity.
文摘A novel efficient partial sharing channelization structure with odd and even stacking is designed and implemented. There are two special designs in the proposed structure. Firstly, by the intensive channel overlap design, for non-cooperative wideband signals, the proposed structure can achieve good parameter estimation accuracy and high probability of complete interception.Secondly, based on the partial sharing design developed in this paper, the computation burden of the proposed structure can be greatly reduced compared with the traditional directly implemented structures. Experiments and numerical simulations are conducted to evaluate the proposed structure, which shows its improvements over traditional methods in terms of field programmable gate arrays(FPGA) resource consumption and parameter estimation accuracy.
文摘Assessing environmental flows (e-flows) for urban rivers is important for water resources planning and river protection, Many e-flow assessment methods have been established based on species' habitat pro- vision requirements and pollutant dilution requirements, To avoid flood risk, however, many urban rivers have been transformed into straight, trapezoidal-profiled concrete channels, leading to the disappearance of valuable species, With the construction of water pollution-control projects, pollutant inputs into rivers have been effectively controlled in some urban rivers, For these rivers, the e-flows determined by tradi- tional methods will be very small, and will consequently lead to a low priority being given to river pro- tection in future water resources allocation and management, To more effectively assess the e-flows of channelized urban rivers, we propose three e-flow degrees, according to longitudinal hydrological con- nectivity (high, medium, and low), in addition to the pollutant dilution water requirement determined by the mass-balance equation, In the high connectivity scenario, the intent is for the e-flows to maintain flow velocity, which can ensure the self-purification of rivers and reduce algal blooms; in the medium connectivity scenario, the intent is for the e-flows to permanently maintain the longitudinal hydrological connectivity of rivers that are isolated into several ponds by means of weirs, in order to ensure the exchange of material, energy, and information in rivers; and in the low connectivity scenario, the intent is for the e-flows to intermittently connect isolated ponds every few days (which is designed to further reduce e-flows), The proposed methods have been used in Shiwuli River, China, to demonstrate their effectiveness, The new methods can offer more precise and realistic e-flow results and can effectively direct the construction and management of e-flow supply projects,
基金supported by Korea Institute of Geoscience and Mineral Resources(Project No.GP2017-024)Ministry of Trade and Industry [Project No.NP2017-021(20172510102090)]funded by National Research Foundation of Korea(NRF)Grants(Nos.NRF-2017R1C1B5017767,NRF-2017K2A9A1A01092734)
文摘Most inverse reservoir modeling techniques require many forward simulations, and the posterior models cannot preserve geological features of prior models. This study proposes an iterative static modeling approach that utilizes dynamic data for rejecting an unsuitable training image(TI) among a set of TI candidates and for synthesizing history-matched pseudo-soft data. The proposed method is applied to two cases of channelized reservoirs, which have uncertainty in channel geometry such as direction, amplitude, and width. Distance-based clustering is applied to the initial models in total to select the qualified models efficiently. The mean of the qualified models is employed as a history-matched facies probability map in the next iteration of static models. Also, the most plausible TI is determined among TI candidates by rejecting other TIs during the iteration. The posterior models of the proposed method outperform updated models of ensemble Kalman filter(EnKF) and ensemble smoother(ES) because they describe the true facies connectivity with bimodal distribution and predict oil and water production with a reasonable range of uncertainty. In terms of simulation time, it requires 30 times of forward simulation in history matching, while the EnKF and ES need 9000 times and 200 times, respectively.
基金financial support from the Science and Technology Service Network Initiative Program of the Chinese Academy of Sciences (grant no.KFJ-EW-STS-094-2)"Hundred Talents" Program of the Chinese Academy of Sciences (Sulijun)+2 种基金the National Natural Science Foundation of China (grant no.41201012, 51208218)the Hundred Young Talents Program of the Institute of Mountain Hazards and Environment (grant no.SDSQB-2013-01)the Chinese Academy of Sciences Visiting Professorship for Senior International Scientists (grant no.2012T1Z0042)
文摘Granular mass flows (e.g., debris flows/avalanches) in landslide-prone areas are of great concern because they often cause catastrophic disasters as a result of their long run-out distances and large impact forces. To investigate the factors influencing granular mass flow mobility, experimental tests were conducted in a flume model. Granular materials consisting of homogeneous sand and non- homogeneous sandy soil were used for studying particle size effects. Run-out tests with variable flow masses, water contents, and sloping channel confinement parameters were conducted as well. The results indicated that granular mass flow mobility was significantly influenced by the initial water content; a critical water content corresponding to the smallest flow mobility exists for different granular materials. An increase in the total flow mass generally induced a reduction in the travel angle (an increase in flow mobility). Consistent with field observations, the travel angles for different granular materials decreased roughly in proportion to the logarithm of mass. The flume model tests illustrate that the measured travel angles increase as the proportion of fine particles increases. Interestingly, natural terrain possesses critical confinement characteristics for different granular mass flows.
文摘Riparian zones of channelized agricultural streams in northwestern Mississippi typically consist of narrow vegetative corridors low in habitat diversity and lacking riparian wetlands. Land clearing practices and stream channelization have led to the development of gully erosion and further fragmentation of these degraded riparian zones. Currently, installation of a gully erosion control structure (drop pipe) at the riparian zone-agricultural field interface leads to the incidental establishment of four riparian habitat types that differ in habitat area, vegetative structure, and pool size. Small mammals were sampled within four sites of each habitat type from June 1994 to July 1995. Small mammal diversity, abundance, and hispid cotton rat (Sigmodon hispidus) weight were the least within smallest Type I habitats with the least vegetative structural diversity and were the greatest within the larger Type II, III, or IV habitats having greater vegetative structural diversity and pool size. Small mammal diversity and abundance were the least in the summer 1994, increased in the fall 1994, and then declined later in our study. Hispid cotton rat abundance was the least in summer 1994, winter 1994, and spring 1995 and was the greatest in fall 1994 and summer 1995. Our results suggest that modifying the drop pipe installation design to facilitate the development of larger riparian habitats with greater vegetative structural diversity will provide the greatest benefits for small mammals.
文摘A structure of dynamic reconfigurable channelized filter bank is proposed in order to solve the problem that the uniform channelized receiver cannot receive the cross-channel and wideband signal. The dynamic reconfigurable channelized filter bank is divided into two parts-the analysis filter bank and the synthesis filter bank. The function of the analysis filter bank is to divide the received signal into several sub-signals according to the channel division. Then the sub-signals of each channel need to be detected and discriminated. At last, we use the sub-signals to reconstruct the original received signal by the synthesis filter bank. The analysis filter and the synthesis filter bank of the dynamic reconfigurable channelized filter bank are all efficient polyphase structures, so it can save more hardware resources and has extensive applicability. The structure is simulated by MATLAB and the simulation results verify the correctness of this structure.
基金the financial support from the National Natural Science Foundation of China(Nos.22205191 and 52002346)the Science and Technology Innovation Program of Hunan Province(No.2021RC3109)+1 种基金the Natural Science Foundation of Hunan Province,China(No.2022JJ40446)Guangxi Key Laboratory of Low Carbon Energy Material(No.2020GXKLLCEM01)。
文摘The concentration difference in the near-surface region of lithium metal is the main cause of lithium dendrite growth.Resolving this issue will be key to achieving high-performance lithium metal batteries(LMBs).Herein,we construct a lithium nitrate(LiNO_(3))-implanted electroactiveβphase polyvinylidene fluoride-co-hexafluoropropylene(PVDF-HFP)crystalline polymorph layer(PHL).The electronegatively charged polymer chains attain lithium ions on the surface to form lithium-ion charged channels.These channels act as reservoirs to sustainably release Li ions to recompense the ionic flux of electrolytes,decreasing the growth of lithium dendrites.The stretched molecular channels can also accelerate the transport of Li ions.The combined effects enable a high Coulombic efficiency of 97.0%for 250 cycles in lithium(Li)||copper(Cu)cell and a stable symmetric plating/stripping behavior over 2000 h at 3 mA cm^(-2)with ultrahigh Li utilization of 50%.Furthermore,the full cell coupled with PHL-Cu@Li anode and Li Fe PO_(4) cathode exhibits long-term cycle stability with high-capacity retention of 95.9%after 900 cycles.Impressively,the full cell paired with LiNi_(0.87)Co_(0.1)Mn_(0.03)O_(2)maintains a discharge capacity of 170.0 mAh g^(-1)with a capacity retention of 84.3%after 100 cycles even under harsh condition of ultralow N/P ratio of 0.83.This facile strategy will widen the potential application of LiNO_(3)in ester-based electrolyte for practical high-voltage LMBs.
基金supported by the National Natural Science Foundation of China,No.82173800 (to JB)Shenzhen Science and Technology Program,No.KQTD20200820113040070 (to JB)。
文摘Na^(+)/K^(+)-ATPase is a transmembrane protein that has important roles in the maintenance of electrochemical gradients across cell membranes by transporting three Na^(+)out of and two K^(+)into cells.Additionally,Na^(+)/K^(+)-ATPase participates in Ca^(2+)-signaling transduction and neurotransmitter release by coordinating the ion concentration gradient across the cell membrane.Na^(+)/K^(+)-ATPase works synergistically with multiple ion channels in the cell membrane to form a dynamic network of ion homeostatic regulation and affects cellular communication by regulating chemical signals and the ion balance among different types of cells.Therefo re,it is not surprising that Na^(+)/K^(+)-ATPase dysfunction has emerged as a risk factor for a variety of neurological diseases.However,published studies have so far only elucidated the important roles of Na^(+)/K^(+)-ATPase dysfunction in disease development,and we are lacking detailed mechanisms to clarify how Na^(+)/K^(+)-ATPase affects cell function.Our recent studies revealed that membrane loss of Na^(+)/K^(+)-ATPase is a key mechanism in many neurological disorders,particularly stroke and Parkinson's disease.Stabilization of plasma membrane Na^(+)/K^(+)-ATPase with an antibody is a novel strategy to treat these diseases.For this reason,Na^(+)/K^(+)-ATPase acts not only as a simple ion pump but also as a sensor/regulator or cytoprotective protein,participating in signal transduction such as neuronal autophagy and apoptosis,and glial cell migration.Thus,the present review attempts to summarize the novel biological functions of Na^(+)/K^(+)-ATPase and Na^(+)/K^(+)-ATPase-related pathogenesis.The potential for novel strategies to treat Na^(+)/K^(+)-ATPase-related brain diseases will also be discussed.
基金supported in part by the National Nature Science Foundation(81874022 and 82172483 to Xinyu Liu,82102522 to Lianlei Wang,82072478 to Yunpeng Zhao,82072435 to Qiang Yang,82073437 to Weiwei Li,81930070 to Shiqing Feng,82272548 to Lei Cheng)Key R&D Project of Shandong Province(2022CXGC010503 to Xinyu Liu)+1 种基金Shandong Natural Science Foundation(ZR202102210113 to Lianlei Wang,ZR2020YQ54 to Yunpeng Zhao)Shandong Province Taishan Scholar Project(tsqn202211317 to Lianlei Wang).The authors thank the Translational Medicine Core Facility of Shandong University for the consultation and instrument availability that supported this work.
文摘To date,several molecules have been found to facilitate iron influx,while the types of iron influx channels remain to be elucidated.Here,Piezo1 channel was identified as a key iron transporter in response to mechanical stress.Piezo1-mediated iron overload disturbed iron metabolism and exaggerated ferroptosis in nucleus pulposus cells(NPCs).Importantly,Piezo1-induced iron influx was independent of the transferrin receptor(TFRC),a well-recognized iron gatekeeper.Furthermore,pharmacological inactivation of Piezo1 profoundly reduced iron accumulation,alleviated mitochondrial ROS,and suppressed ferroptotic alterations in stimulation of mechanical stress.Moreover,conditional knockout of Piezo1(Col2a1-CreERT Piezo1^(flox/flox))attenuated the mechanical injury-induced intervertebral disc degeneration(IVDD).Notably,the protective effect of Piezo1 deficiency in IVDD was dampened in Piezo1/Gpx4 conditional double knockout(cDKO)mice(Col2a1-CreERT Piezo1^(flox/flox)/Gpx4^(flox/flox)).These findings suggest that Piezo1 is a potential determinant of iron influx,indicating that the Piezo1-iron-ferroptosis axis might shed light on the treatment of mechanical stress-induced diseases.
基金financially supported by the National Key Research and Development Program(Grant No.2022YFE0107000)the General Projects of the National Natural Science Foundation of China(Grant No.52171259)the High-Tech Ship Research Project of the Ministry of Industry and Information Technology(Grant No.[2021]342)。
文摘Identification of the ice channel is the basic technology for developing intelligent ships in ice-covered waters,which is important to ensure the safety and economy of navigation.In the Arctic,merchant ships with low ice class often navigate in channels opened up by icebreakers.Navigation in the ice channel often depends on good maneuverability skills and abundant experience from the captain to a large extent.The ship may get stuck if steered into ice fields off the channel.Under this circumstance,it is very important to study how to identify the boundary lines of ice channels with a reliable method.In this paper,a two-staged ice channel identification method is developed based on image segmentation and corner point regression.The first stage employs the image segmentation method to extract channel regions.In the second stage,an intelligent corner regression network is proposed to extract the channel boundary lines from the channel region.A non-intelligent angle-based filtering and clustering method is proposed and compared with corner point regression network.The training and evaluation of the segmentation method and corner regression network are carried out on the synthetic and real ice channel dataset.The evaluation results show that the accuracy of the method using the corner point regression network in the second stage is achieved as high as 73.33%on the synthetic ice channel dataset and 70.66%on the real ice channel dataset,and the processing speed can reach up to 14.58frames per second.
基金supported by the Key R&D Project of the Ministry of Science and Technology of China(2020YFB1808005)。
文摘Low Earth Orbit(LEO)multibeam satellites will be widely used in the next generation of satellite communication systems,whose inter-beam interference will inevitably limit the performance of the whole system.Nonlinear precoding such as Tomlinson-Harashima precoding(THP)algorithm has been proved to be a promising technology to solve this problem,which has smaller noise amplification effect compared with linear precoding.However,the similarity of different user channels(defined as channel correlation)will degrade the performance of THP algorithm.In this paper,we qualitatively analyze the inter-beam interference in the whole process of LEO satellite over a specific coverage area,and the impact of channel correlation on Signal-to-Noise Ratio(SNR)of receivers when THP is applied.One user grouping algorithm is proposed based on the analysis of channel correlation,which could decrease the number of users with high channel correlation in each precoding group,thus improve the performance of THP.Furthermore,our algorithm is designed under the premise of co-frequency deployment and orthogonal frequency division multiplexing(OFDM),which leads to more users under severe inter-beam interference compared to the existing research on geostationary orbit satellites broadcasting systems.Simulation results show that the proposed user grouping algorithm possesses higher channel capacity and better bit error rate(BER)performance in high SNR conditions relative to existing works.
基金supported in part by the National Natural Science Foundation of China(NSFC)under Grants 61941104,61921004the Key Research and Development Program of Shandong Province under Grant 2020CXGC010108+1 种基金the Southeast University-China Mobile Research Institute Joint Innovation Centersupported in part by the Scientific Research Foundation of Graduate School of Southeast University under Grant YBPY2118.
文摘The great potentials of massive Multiple-Input Multiple-Output(MIMO)in Frequency Division Duplex(FDD)mode can be fully exploited when the downlink Channel State Information(CSI)is available at base stations.However,the accurate CsI is difficult to obtain due to the large amount of feedback overhead caused by massive antennas.In this paper,we propose a deep learning based joint channel estimation and feedback framework,which comprehensively realizes the estimation,compression,and reconstruction of downlink channels in FDD massive MIMO systems.Two networks are constructed to perform estimation and feedback explicitly and implicitly.The explicit network adopts a multi-Signal-to-Noise-Ratios(SNRs)technique to obtain a single trained channel estimation subnet that works well with different SNRs and employs a deep residual network to reconstruct the channels,while the implicit network directly compresses pilots and sends them back to reduce network parameters.Quantization module is also designed to generate data-bearing bitstreams.Simulation results show that the two proposed networks exhibit excellent performance of reconstruction and are robust to different environments and quantization errors.
基金supported in part by the Sichuan Science and Technology Program(Grant No.2023YFG0316)the Industry-University Research Innovation Fund of China University(Grant No.2021ITA10016)+1 种基金the Key Scientific Research Fund of Xihua University(Grant No.Z1320929)the Special Funds of Industry Development of Sichuan Province(Grant No.zyf-2018-056).
文摘Due to the interdependency of frame synchronization(FS)and channel estimation(CE),joint FS and CE(JFSCE)schemes are proposed to enhance their functionalities and therefore boost the overall performance of wireless communication systems.Although traditional JFSCE schemes alleviate the influence between FS and CE,they show deficiencies in dealing with hardware imperfection(HI)and deterministic line-of-sight(LOS)path.To tackle this challenge,we proposed a cascaded ELM-based JFSCE to alleviate the influence of HI in the scenario of the Rician fading channel.Specifically,the conventional JFSCE method is first employed to extract the initial features,and thus forms the non-Neural Network(NN)solutions for FS and CE,respectively.Then,the ELMbased networks,named FS-NET and CE-NET,are cascaded to capture the NN solutions of FS and CE.Simulation and analysis results show that,compared with the conventional JFSCE methods,the proposed cascaded ELM-based JFSCE significantly reduces the error probability of FS and the normalized mean square error(NMSE)of CE,even against the impacts of parameter variations.
基金the Ethics Committee of University Magdeburg(Ethical code:33/0119.03.2001).
文摘Transient receptor potential(TRP)channels are strongly associated with colon cancer development and progression.This study leveraged a multivariate Cox regression model on publicly available datasets to construct a TRP channels-associated gene signature,with further validation of signature in real world samples from our hospital treated patient samples.Kaplan-Meier(K-M)survival analysis and receiver operating characteristic(ROC)curves were employed to evaluate this gene signature’s predictive accuracy and robustness in both training and testing cohorts,respectively.Additionally,the study utilized the CIBERSORT algorithm and single-sample gene set enrichment analysis to explore the signature’s immune infiltration landscape and underlying functional implications.The support vector machine algorithm was applied to evaluate the signature’s potential in predicting chemotherapy outcomes.The findings unveiled a novel three TRP channels-related gene signature(MCOLN1,TRPM5,and TRPV4)in colon adenocarcinoma(COAD).The ROC and K-M survival curves in the training dataset(AUC=0.761;p=1.58e-05)and testing dataset(AUC=0.699;p=0.004)showed the signature’s robust predictive capability for the overall survival of COAD patients.Analysis of the immune infiltration landscape associated with the signature revealed higher immune infiltration,especially an increased presence of M2 macrophages,in high-risk group patients compared to their low-risk counterparts.High-risk score patients also exhibited potential responsiveness to immune checkpoint inhibitor therapy,evident through increased CD86 and PD-1 expression profiles.Moreover,the TRPM5 gene within the signature was highly expressed in the chemoresistance group(p=0.00095)and associated with poor prognosis(p=0.036)in COAD patients,highlighting its role as a hub gene of chemoresistance.Ultimately,this signature emerged as an independent prognosis factor for COAD patients(p=6.48e-06)and expression of model gene are validated by public data and real-world patients.Overall,this bioinformatics study provides valuable insights into the prognostic implications and potential chemotherapy resistance mechanisms associated with TRPs-related genes in colon cancer.
基金supported by the Natural Science Foundation of Anhui Province of China,No.2208085Y32Scientific Research Plan Project of Anhui Province of China,No.2022AH020076the Chen Xiao-Ping Foundation for the Development of Science and Technology of Hubei Province,No.CXPJJH12000005-07-115(all to CT).
文摘Calcium influx into neurons triggers neuronal death during cerebral ischemia/reperfusion injury.Various calcium channels are involved in cerebral ischemia/reperfusion injury.Cav3.2 channel is a main subtype of T-type calcium channels.T-type calcium channel blockers,such as pimozide and mibefradil,have been shown to prevent cerebral ischemia/reperfusion injury-induced brain injury.However,the role of Cav3.2 channels in cerebral ischemia/reperfusion injury remains unclear.Here,in vitro and in vivo models of cerebral ischemia/reperfusion injury were established using middle cerebral artery occlusion in mice and high glucose hypoxia/reoxygenation exposure in primary hippocampal neurons.The results showed that Cav3.2 expression was significantly upregulated in injured hippocampal tissue and primary hippocampal neurons.We further established a Cav3.2 gene-knockout mouse model of cerebral ischemia/reperfusion injury.Cav3.2 knockout markedly reduced infarct volume and brain water content,and alleviated neurological dysfunction after cerebral ischemia/reperfusion injury.Additionally,Cav3.2 knockout attenuated cerebral ischemia/reperfusion injury-induced oxidative stress,inflammatory response,and neuronal apoptosis.In the hippocampus of Cav3.2-knockout mice,calcineurin overexpression offset the beneficial effect of Cav3.2 knockout after cerebral ischemia/reperfusion injury.These findings suggest that the neuroprotective function of Cav3.2 knockout is mediated by calcineurin/nuclear factor of activated T cells 3 signaling.Findings from this study suggest that Cav3.2 could be a promising target for treatment of cerebral ischemia/reperfusion injury.