Evaluation of the Sensitivity and Specificity of the New Clinical Diagnostic and Classification Criteria for Kashin-Beck Disease,an Endemic Osteoarthritis,in China

This study aimed to evaluate the sensitivity and specificity of the new clinical diagnostic and classification criteria for Kashin-Beck disease （KBD） using six clinical markers： flexion of the distal part of fingers, deformed fingers, enlarged finger joints, shortened fingers, squat down, and dwarfism. One-third of the total population in Linyou County was sampled by stratified random sampling.

Siting of Dark Sky Reserves in China Based on Multi-source Spatial Data and Multiple Criteria Evaluation Method

With the rapid development of population and urbanization and the progress of lighting technology, the influence of artificial light sources has increased.In this context, the problem of light pollution has attracted wide attention.Previous studies have revealed that light pollution can affect biological living environments, human physical and mental health, astronomical observations and many other aspects.Therefore, organizations internationally have begun to advocate for measures to prevent light pollution, many of which are recognized by the International Dark-Sky Association(IDA).In addition to improving public awareness, legal protections, technical treatments and other means, the construction of Dark Sky Reserves(DSR) has proven to be an effective preventive measure.So far, as a pioneer practice in this field, the IDA has identified 11 DSRs worldwide.Based on the DA requirements for DSRs, this paper utilizes NPP-VIIRS nighttime light data and other multi-source spatial data to analyze possible DSR sites in China.The land of China was divided into more than ten thousand 30 km × 30 km fishnets, and constraint and suitable conditions were designated, respectively, as light and cloud conditions, and scale, traffic and attractiveness conditions.Using a multiple criteria evaluation, 1443 fishnets were finally selected as most suitable sites for the construction of DSRs.Results found that less than 25% of China is not subject to light pollution, and less than 13% is suitable for DSR construction, primarily in western and northern areas, including Tibet, Xinjiang, Qinghai, Gansu and Inner Mongolia.

Mass-transport Deposits of the Upper Cretaceous Qingshankou Formation, Songliao Terrestrial Basin, Northeast China: Depositional Characteristics, Recognition Criteria and External Geometry

Extensive mass transport deposits（MTDs）, which form a significant component of the stratigraphic record in ancient and modern deep water systems, mostly distributed in the continental margin of ocean basins worldwide. To date, no large-scale MTDs have been found in Chinese terrestrial basins. Based on integrated analysis of the seismic, drilling, core and logging data, this article report MTDs have been found in Songliao terrestrial basin（SLTB）, Northeast China. During the depositional period of the Upper Cretaceous Qingshankou Formation, slope break of lacustrine basins was an ideal discharge place for gravity depositions. Regional sedimentary study of MTDs reveals that Cretaceous-age MTDs in SLTB were deposited in slope-break environments by slide, slump and debris flow, and MTDs were mixed with little turbidite simultaneously. Besides the massive aspect, key features of MTDs are the common presence of deformational structures or softsedimentary deformation, floating shale clasts, boudins, microfaults, distortion beddings, rotated sand debris. Detailed mapping of two three-dimensional（3-D） seismic surveys acquired in Yingtai（YT） and Haituozi（HTZ） areas reveals that MTDs are characterized by chaotic, mounded, and transparent seismic reflection. Growth fault, slope gully and geomorphology of the slope break greatly influenced the sedimentary process and external geometry of MTDs, and as a consequence, MTDs in SLTB exhibit classic fan-like geometry and some special（non-fan-like） external geometry. Furthermore, fanlike MTDs can be divided into three subcategories, including isolated fan, mother-son fan and stacked fan. Non-fan-like MTDs can be divided into two subcategories, strip-like MTDs and faulted-pit MTDs. A new sedimentary model has been built for MTDs in SLTB. MTDs have become a new exploration and development target in the SLTB.

Developing nutrient criteria for the Jiulong River Estuary,Southeast China

One of the key concerns in estuarine and coastal environments is eutrophication, which is known to be closely connected to nutrient enrichment. To control and improve surface water quality, nutrient criteria are recommended in order to provide reference conditions for the environment. However, the current datasets of nutrient criteria in China are either designed for surface water or sea water, and as such these are not suitable for assessing estuarine water quality, especially given the unique ecosystem and dynamic properties of estuaries. To address this issue in current estuarine water management, nutrient criteria have been developed for a local estuary in the southeast of China. Segmentation of the Jiulong River Estuary, China was firstly analysed through field investigations carried out during 2013–2014, which resulted in the delineation of three segments characterized by their distinct properties in relation to salinity, hydrology, ecosystems, etc. Historical records from 1997 to 2014 were then analysed using statistical modelling to develop candidate nutrient criteria for the estuary.This stage of the analysis was undertaken in combination with the study of nutrient status records from the 1980s,which were used to establish a baseline reference condition. The recommended criteria values of dissolved inorganic nitrogen（DIN） in Segments Ⅰ, Ⅱ and Ⅲ of the Jiulong River Estuary are 64, 21 and 14 μmol/L,respectively, and the corresponding values for soluble reactive phosphorus（SRP） are 0.89, 0.76 and 0.89 μmol/L,respectively. It should be emphasised that these values are site-dependent, and that different results may be achieved at other locations depending on the physical and biogeochemical characteristics of an estuary, or even a single site within a catchment. It is hoped that by demonstrating a possible methodological approach and methods of nutrient criteria derivation in the Jiulong River Estuary, the current study will offer researchers some fundamental basis from which to begin to develop more complete nutrient criteria indices for the study of nutrient conditions in other estuaries throughout China.

Deriving freshwater quality criteria of sulphocyanic sodium for the protection of aquatic life in China

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Geological Characteristics and Prospecting Criteria of Senji Molybdenum Ore Body in Urad Houqi, Inner Mongolia, China

Geological Characteristics and Prospecting Indicators of Senji Molybdenum Ore Body in Urad Houqi, Inner Mongolia Based on geological mapping, soil geochemical survey, surface trough exploration and deep drilling verification and control, the Senji Molybdenum deposit was discovered. Geological characteristics of the molybdenum ore body are described. The host lithology of molybdenum ore body is mainly in the cataclastic carbonated black plagioclase gneiss of the second rock member of the Paleoproterozoic Baoyintu Group, followed by Early Carboniferous monzogranite. The genetic type of the deposit is preliminarily deduced to be a hydrothermal filling vein-type molybdenum deposit. The significance of this paper is to summarize the prospecting marks of the molybdenum ore body in this area, so as to further guide the exploration work in this area, and at the same time provide a useful reference for the exploration work of similar deposits in other areas.

The Derivation of Nutrient Criteria for the Adjacent Waters of Yellow River Estuary in China

Ecological protection and high-quality development of the Yellow River basin are becoming part of the national strategy in recent years.The Yellow River Estuary has been seriously affected by human activities.Especially,it has been severely polluted by the nitrogen and phosphorus from land sources,which have caused serious eutrophication and harmful algal blooms.Nutrient criteria,however,was not developed for the Yellow River Estuary,which hindered nutrient management measures and eutrophication risk assessment in this key ecological function zone of China.Based on field data during 2004-2019,we adopted the frequency distribution method,correlation analysis,Linear Regression Model(LRM),Classification and Regression Tree(CART)and Nonparametric Changepoint Analysis(nCPA)methods to establish the nutrient criteria for the adjacent waters of Yellow River Estuary.The water quality criteria of dissolved inorganic nitrogen(DIN)and soluble reactive phosphorus(SRP)are recommended as 244.0μg L^(−1) and 22.4μg L^(−1),respectively.It is hoped that the results will provide scientific basis for the formulation of nutrient standards in this important estuary of China.

Interpretation Criteria for Standardized Western Blot for the Predominant Species of Borrelia Burgdorferi Sensu Lato in China

Objective Western blotting （WB;immunoblotting） is a widely used tool for the serodiagnosis of Lyme borreliosis （LB）,but so far,no generally accepted criteria for its performance and interpretation have been established in China.The present study was designed to determine the criteria for standardized Western blot for the predominant species of Borrelia burgdorferi sensu lato in China,in which WB was produced with strain PD91 as the representative strain attributed to predominant genospecies Borrelia garinii of Borrelia burgdorferi sensu lato.Methods Approximately 13 bands between 14 and 100 kD were differentiated for strain PD91 by using Gel-Pro analysis software.In a study with 631 serum samples （taken from 127 patients with Lyme borreliosis and 504 controls）,all observed bands were documented.To establish criteria for a positive WB result for strain PD91,receiver operating characteristic （ROC） curves were used.Results The following interpretation criteria were recommended：for IgG,at least one band of P83/100,P58,P39,P30,OspC,P17,P66,and OspA;for IgM,at least one band of P83/100,P58,OspA,P30,OspC,P17 or P41.In addition,syphilis,leptospirosis and other related diseases should be excluded when the positive band is P41 in IgM.For IgG criteria,the sensitivity is 73.2%,the specificity is 99.4% and Youden index is 0.726;for IgM criteria,the sensitivity is 50.6%,the specificity is 93.1% and Youden index is 0.437.Conclusion Standardization of WB assays is necessary for comparison of results from different laboratories.Moreover,the criteria of other genospecies of Borrelia burgdorferi sensu lato should be determined in the future to complete the criteria of WB for the diagnosis of the Lyme disease in China.

A review on rules for examination of licensing criteria for producing foods for special medical purpose in China

In this paper,the background,principles,and main contents of the rules for the examination of production licenses of foods for special medical purposes are introduced.The contents including general rules,production sites,equipment facilities,equipment layout,technological process,personnel management,management system and supplementary rules are interpreted item by item.This study has important value and historical significance for promoting the development of Chinese enterprises and industries of foods for special medical purposes.

Stipulation of the criteria for the construction of eco agricultural county in China

The criteria for the construction of an eco agricultural county in China were suggested. The criteria should coordinate social, economic, and environmental effects together. At first, it emphasizes on the social effect input into the system, which includes population control, cultural, scientific, and moral education, technical training and so on. Secondly, economic criteria are mainly those of the increase of gross national product(GNP) and income per capita every year. Finally, the technical criteria consist of not only the grain yield, commodity percentage of the agricultural product, cultivated output/input, animal husbandry production value/total agricultural production value and other agricultural criteria, but also environmental criteria, such as the percentage of forest and grass cover, degenerated land under control, recycling of organic waste, recommended fertilization, integrated pest management, treatment of discharged wastes and others. In an eco agricultural system, the realization of these criteria by three different development steps were recommended too.

Impacts of Future Changes in Heavy Precipitation and Extreme Drought on the Economy over South China and Indochina

Heavy precipitation and extreme drought have caused severe economic losses over South China and Indochina(INCSC)in recent decades.Given the areas with large gross domestic product(GDP)in the INCSC region are distributed along the coastline and greatly affected by global warming,understanding the possible economic impacts induced by future changes in the maximum consecutive 5-day precipitation(RX5day)and the maximum consecutive dry days(CDD)is critical for adaptation planning in this region.Based on the latest data released by phase 6 of the Coupled Model Intercomparison Project(CMIP6),future projections of precipitation extremes with bias correction and their impacts on GDP over the INCSC region under the fossil-fueled development Shared Socioeconomic Pathway(SSP5-8.5)are investigated.Results indicate that RX5day will intensify robustly throughout the INCSC region,while CDD will lengthen in most regions under global warming.The changes in climate consistently dominate the effect on GDP over the INCSC region,rather than the change of GDP.If only considering the effect of climate change on GDP,the changes in precipitation extremes bring a larger impact on the economy in the future to the provinces of Hunan,Jiangxi,Fujian,Guangdong,and Hainan in South China,as well as the Malay Peninsula and southern Cambodia in Indochina.Thus,timely regional adaptation strategies are urgent for these regions.Moreover,from the sub-regional average viewpoint,over two thirds of CMIP6 models agree that maintaining a lower global warming level will reduce the economic impacts from heavy precipitation over the INCSC region.

Intensity Allocation Criteria of Carbon Emissions Permits and Regional Economic Development in China——Based on a 30-Province/Autonomous Region Computable General Equilibrium Model

在瓷器地区性的开发的碳排出物许可证和它的影响的紧张分配标准通过 30-province/autonomous 区域被分析可计算出来的一般平衡(CGE ) 模型。模拟结果显示出那：没有进行地区性的经济开发进帐号的工业紧张标准加深地区性的经济开发的 unbalance；没有考虑工业性质的地区性的紧张标准几乎不在地区性的和谐开发，而是对高碳的排放工业的相对高的否定影响施加很少否定影响。中央政府分配的二拍子的圆舞分配计划到省的政府的排出物许可证基于工业性质基于地区性的经济开发然后省的政府分配排出物许可证到排放资源或实体是一种可行、合用的选择。引证元， Y.-N. ， M.-J. 史， N. 李，等， 2012：在中国的碳排出物许可证和地区性的经济开发的紧张分配标准基于一个 30-province/autonomous 区域可计算出来的一般平衡模型。副词。Clim。变化物件， 3 (3 ) ， doi：10.3724/SP .J.1248.2012.00154。

Resilience effects for household food expenditure and dietary diversity in rural western China

A more resilient livelihood is increasingly recognized as an efficient way to improve vulnerable households’food security and optimize their dietary decisions.This study quantifies rural household resilience in western China,identifies the three pillars(absorptive capacity,adaptive capacity,and transformative capacity)contribution to resilience,and then establishes the estimated Resilience Capacity Index(RCI)linked with food security and dietary diversity supported by the multiple indicator multiple cause(MIMIC)model.Results show that,despite geographical heterogeneity,the RCI consistently increased from 2015 to 2021.Households with a higher RCI inheriting better capacity to deal with risk and shocks are significantly and positively correlated with increasing food expenditure and diversifying food choices.It can be because resilient households will allocate more money to food expenditure instead of saving for livelihood uncertainty.Thus,policymakers can provide more incentives for rural households to adopt more dynamic and effective risk management strategies.This,in turn,could yield positive spillover effects by preventing human capital loss associated with dietary-related chronic diseases and mortality.

How do the landslide and non-landslide sampling strategies impact landslide susceptibility assessment? d A catchment-scale case study from China

The aim of this study is to investigate the impacts of the sampling strategy of landslide and non-landslide on the performance of landslide susceptibility assessment(LSA).The study area is the Feiyun catchment in Wenzhou City,Southeast China.Two types of landslides samples,combined with seven non-landslide sampling strategies,resulted in a total of 14 scenarios.The corresponding landslide susceptibility map(LSM)for each scenario was generated using the random forest model.The receiver operating characteristic(ROC)curve and statistical indicators were calculated and used to assess the impact of the dataset sampling strategy.The results showed that higher accuracies were achieved when using the landslide core as positive samples,combined with non-landslide sampling from the very low zone or buffer zone.The results reveal the influence of landslide and non-landslide sampling strategies on the accuracy of LSA,which provides a reference for subsequent researchers aiming to obtain a more reasonable LSM.

The impact of Internet access on household dietary quality:Evidence from rural China

Over the past few decades,the Internet has rapidly diffused across China.The spread of the Internet has had a profound economic and social impact on Chinese rural areas.Existing research shows that Internet access significantly impacts agricultural production and improves smallholder farmers’income.Beyond these,the Internet can affect other dimensions of social welfare.However,research about the impact of Internet access on dietary quality in rural China remains scarce.This study utilizes multi-period panel data from Fixed Observation Point in rural China from 2009 to 2015 to estimate the impact of Internet access on dietary quality and food consumption of rural households and conducts a causal analysis.Regression models with time and household fixed effects allow robust estimation while reducing potential issues of unobserved heterogeneity.The estimates show that Internet access has significantly increased rural household dietary quality(measured by the Chinese Diet Balance Index).Further research finds that Internet access has increased the consumption of animal products,such as aquatic and dairy products.We also examine the underlying mechanisms.Internet access improves dietary quality and food consumption mainly through increasing household income and food expenditure.These results encourage the promotion of Internet access as a valuable tool for nutritional improvements,especially in rural areas.

基于AHP和熵值法China Daily头版封面插画视觉感知评价研究

为了探索报纸插图视觉中哪些因素对读者产生影响,提升阅读者的视觉感知水平,以China Daily头版封面插画为例,从内容层、形式、功能感知三个维度,建构出审美艺术性、创意趣味性、风格独特性、符号内涵性、标题内容区分度、色调内容协调度、色调舒适度、明度舒适度、纯度舒适度、图形大小舒适度、图形造型舒适度、构图留白舒适度等24个指标。结合问卷调查,利用层次分析法和熵值法进行统计分析。研究得出:读者对于China Daily封面插画的感知评价由高到低依次为形式层感知、功能层感知、内容层感知;构图留白舒适度、阅读动态性、叙事直观性等因素对读者视觉感知影响较大;从优化读者文化继承性、字体设计协调度、主题明确性等方面入手,有助于提升读者的视觉阅读体验。

对外传播中的福州城市形象话语建构——以“十三五”期间China Daily报道为例

以“十三五”期间China Daily有关福州的报道为语料,以文化话语研究为理论框架,从话语主体、话语主题和话语形式三个方面探讨福州城市形象的话语建构。研究发现,总体上China Daily对外塑造了一个积极的福州城市形象,其中以文化形象最受关注。此外,与以往同类研究相比,样本媒体进一步传递了普通民众的声音,更多使用人物通讯的报道形式,从而更有效地对外讲述了福州故事、中国故事。本研究对城市形象的话语建构与国际传播具有现实意义。

Differences in spring precipitation over southern China associated with multiyear La Ni?a events

Composite analyses were performed in this study to reveal the difference in spring precipitation over southern China during multiyear La Ni?a events during 1901 to 2015. It was found that there is significantly below-normal precipitation during the first boreal spring, but above-normal precipitation during the second year. The difference in spring precipitation over southern China is correlative to the variation in western North Pacific anomalous cyclone(WNPC), which can in turn be attributed to the different sea surface temperature anomaly(SSTA) over the Tropical Pacific. The remote forcing of negative SSTA in the equatorial central and eastern Pacific and the local air-sea interaction in the western North Pacific are the usual causes of WNPC formation and maintenance.SSTA in the first spring is stronger than those in the second spring. As a result, the intensity of WNPC in the first year is stronger, which is more likely to reduce the moisture in southern China by changing the moisture transport, leading to prolonged precipitation deficits over southern China. However, the tropical SSTA signals in the second year are too weak to induce the formation and maintenance of WNPC and the below-normal precipitation over southern China. Thus, the variation in tropical SSTA signals between two consecutive springs during multiyear La Ni?a events leads to obvious differences in the spatial pattern of precipitation anomaly in southern China by causing the different WNPC response.

Epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China:a hospital-based retrospective study

Traumatic spinal cord injury is potentially catastrophic and can lead to permanent disability or even death.China has the largest population of patients with traumatic spinal cord injury.Previous studies of traumatic spinal cord injury in China have mostly been regional in scope;national-level studies have been rare.To the best of our knowledge,no national-level study of treatment status and economic burden has been performed.This retrospective study aimed to examine the epidemiological and clinical features,treatment status,and economic burden of traumatic spinal cord injury in China at the national level.We included 13,465 traumatic spinal cord injury patients who were injured between January 2013 and December 2018 and treated in 30 hospitals in 11 provinces/municipalities representing all geographical divisions of China.Patient epidemiological and clinical features,treatment status,and total and daily costs were recorded.Trends in the percentage of traumatic spinal cord injuries among all hospitalized patients and among patients hospitalized in the orthopedic department and cost of care were assessed by annual percentage change using the Joinpoint Regression Program.The percentage of traumatic spinal cord injuries among all hospitalized patients and among patients hospitalized in the orthopedic department did not significantly change overall(annual percentage change,-0.5%and 2.1%,respectively).A total of 10,053(74.7%)patients underwent surgery.Only 2.8%of patients who underwent surgery did so within 24 hours of injury.A total of 2005(14.9%)patients were treated with high-dose(≥500 mg)methylprednisolone sodium succinate/methylprednisolone(MPSS/MP);615(4.6%)received it within 8 hours.The total cost for acute traumatic spinal cord injury decreased over the study period(-4.7%),while daily cost did not significantly change(1.0%increase).Our findings indicate that public health initiatives should aim at improving hospitals’ability to complete early surgery within 24 hours,which is associated with improved sensorimotor recovery,increasing the awareness rate of clinical guidelines related to high-dose MPSS/MP to reduce the use of the treatment with insufficient evidence.

Multi-Model Approach for Assessing the Influence of Calibration Criteria on the Water Balance in Ouémé Basin

Hydrological models are very useful tools for evaluating water resources, and the hydroclimatic hazards associated with the water cycle. However, their calibration and validation require the use of performance criteria which choice is not straightforward. This paper aims to evaluate the influence of the performance criteria on water balance components and water extremes using two global rainfall-runoff models (HBV and GR4J) over the Ouémé watershed at the Bonou and Savè outlets. Three (3) Efficacy criteria (Nash, coefficient of determination, and KGE) were considered for calibration and validation. The results show that the Nash criterion provides a good assessment of the simulation of the different parts of the hydrograph. KGE is better for simulating peak flows and water balance elements than other efficiency criteria. This study could serve as a basis for the choice of performance criteria in hydrological modelling.