The Application of Newmark’s Metaphor Theory in Novel Translation--A Case Study of“the Jade King:History of a Chinese Muslim Family”

This paper examines the metaphorical part of“The Jade King:History of a Chinese Muslim Family”,Hoda’s novel,under the guidance of Newmark’s theory of metaphor.Newmark proposes six categories of metaphors,namely Dead Metaphor,ClichéMetaphor,Stock or Standard Metaphor,Adapted Metaphor,Recent Metaphor,Original Metaphor;and seven strategies of metaphor translation,including reproducing the same image in the target language,replacing the image in the source language with a standard target language image,translation of metaphor by simile,translation of metaphor(or simile)by simile plus sense,conversion of metaphor to sense,deletion and same metaphor combined with sense.They can provide a strong theoretical support for analyzing the expressions of metaphors in novels and their translation methods.By deeply analyzing the expressions of metaphor and its translation methods in novels,it not only helps to understand the metaphorical meaning and cultural connotation of the original works,but also helps to explore the cultural differences and challenges faced by English and Chinese bilingualism in the process of metaphor translation,thereby significantly improving the translation level and promoting the development of translation research.

The Influence of Integrated Chinese and Western Medicine Treatment on the Quality of Life and Laboratory Indicators of Patients with Novel Coronavirus Pneumonia

Objective: To investigate the influence of integrated Chinese and Western medicine treatment on the quality of life and laboratory indicators of patients with novel coronavirus pneumonia (COVID-19). Methods: A prospective, self-controlled study was conducted to analyze the changes in corresponding laboratory indicators and quality of life in 75 confirmed COVID-19 patients treated with integrated Chinese and Western medicine in our hospital during the early stage, middle stage, recovery period, and two weeks after discharge. The effectiveness and safety of the treatment regimen were evaluated in conjunction with the time for 2019-nCoV nucleic acid conversion, disease progression, and adverse reactions. Results: The PLT levels in the initial stage were significantly lower than those in the recovery period in 75 patients. The CRP levels in the initial stage were significantly lower than those after discharge for 2 weeks. The TBIL, IBTL, and DHIL levels in the initial stage were significantly lower than those in the middle stage. The K+ levels in the initial stage were significantly lower than those in the recovery period and after discharge for 2 weeks. The LYMGH levels in the initial stage were significantly lower than those in the recovery period and after discharge for 2 weeks. The TP and ALB levels in the initial stage were higher than those in the middle stage and the recovery period. The LDH levels, scores of daily activity limitation, scores of respiratory distress symptoms, scores of psychological emotions, CT imaging scores, and positive rate of nucleic acid were significantly lower than those in the recovery period and after discharge for 2 weeks. The AG, CK, CK-MB, and α-HBDH levels in the initial stage were significantly higher than those in the recovery period. However, the AMY level in the initial stage was significantly lower than that in the recovery period and after discharge for 2 weeks (p Conclusion: Integrated Chinese and Western medicine treatment has a significant impact on laboratory indicators such as PLT, LYMGH, CRP, TBIL, IBTL, DHIL, TP, ALB, K+, AG, LDH, CK, CK-MB, α-HBDH, AMY, CT imaging, and 2019-nCoV nucleic acid in COVID-19 patients. It has good clinical efficacy and safety, and can improve the quality of life of patients.

A Novel Sample Introduction Technique for the Simultaneous Determination of As,Se,Ge and Hg in Chinese Medicinal Material

A novel technique of Moveable Reduction Bed Hydride Generator（MRBHG）was applied tohe hydride generation or cold vapor generation of As，Se，Ge，and Hg existing In TraditionalChinese Medicinal Material（TCM）．The simultaneous determination of the multi－elements wasperformed with ICP－MS．A solid reduction system involving the use of potassiumtetraborohydride and tartaric acid was applied to generating metal hydride or cold vaporefficiently．The factors affecting the metal cold vapor generation were studied．The mainadvantage of the technique is that only a 4μL volume of sample was required for the cold vapor

Efficacy and mechanisms of Traditional Chinese Medicine prevention and treatment for respiratory viruses

Respiratory virus infection was the most common viral infection in clinical practice with the greatest impact,including the Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),posing a huge threat to the world's public health and human life safety.Commonly used antiviral drugs have obvious side effects and a narrow scope of application.Respiratory viruses are susceptible to infection,mutation,and prevalence,which also pose challenges to traditional antiviral drugs and vaccine development.Traditional Chinese Medicine(TCM)has a long history of treating infectious diseases,with many herbs and compounds.Its multi-component,multi-target and multi-path characteristics have made it have great advantages and potential in the development of new anti-respiratory virus drugs.This review summarized TCM for the prevention and treatment of common respiratory viruses,and provided new strategies for the research and development of new TCM antiviral drugs and for responding to infectious respiratory virus diseases.

A novel phenotype with splicing mutation identified in a Chinese family with desminopathy

Background and Objective Desminopathy is a largely heterogeneous group of conditions involving inherited or sporadic myofibrillar myopathy.In terms of its mode of inheritance,the autosomal dominant form is predominant.Desmin gene(DES)mutations play a critical role among the pathogenic inherited factors associated with desminopathy.Desminopathy involves various phenotypes,mainly including different cardiomyopathies,skeletal myopathy and arrhythmia.The purposes of this study are characterization of a novel phenotype and identification of a DES splicing mutation in a Chinese family with desminnopathy.

Analysis of novel coronavirus pneumonia treatment with Chinese herbal compound

Objective: To analyze the prescription law of TCM compound in the treatment of new coronavirus pneumonia, and provides reference for the clinical treatment of new coronavirus pneumonia. Methods: Collected Collected 24 novel coronavirus pneumonia related diagnostic and therapeutic plans issued by the National Health Council and the Chinese medicine authority from January 26, 2020 to March 8th ,the filtered solution involved in the formula, establishing database of traditional Chinese medicine compound prescription for the treatment of new crown pneumonia, the frequency of using frequency analysis methods of analysis and clustering analysis and association rules analysis to sort out data mining analysis of traditional Chinese medicine compound. Results: In this study, a total of 159 TCM compounds were included in the treatment of new crown pneumonia from the country and 23 provinces, municipalities and autonomous regions, involving 189 TCM compounds. A total of 62 high-frequency traditional Chinese medicines (frequency ≥ 11) were obtained, mainly including licorice, almond, ephedra, gypsum, Poria cocos, Huoxiang, etc The drug types are mainly heat-clearing drugs, vacuous drugs, moisture-curing drugs, and surfactant drugs. The main effect of the medicine was warm, cold, lukewarm and flat, the main effect of the medicine was bitter and bitter, and the main effect of the medicine was the lung, stomach and spleen. Cluster analysis results according to the performance of traditional Chinese medicine treatment of new crown pneumonia high frequency drugs into 7 classes;Association rule analysis results in 29 common drug pairs. Conclusion: In the treatment of pneumonia caused by new coronavirus infection with traditional Chinese medicine, the following characteristics are presented: the number of times of supplementing qi and Yin is more than that of attacking evil and maintaining health;The method of dispersing and solving the attack of wet, beneficial, wet, permeable and wet medicine fully embodies a variety of ways to drive away evil;In terms of drugs, heat-clearing drugs, deficiency drugs, dampness drugs and surface drugs are the main ones, highlighting that the basic treatment method is to dissolve dampness and detoxify, and replenish qi and Yin. In summary, this study can provide reference for guiding clinical drug use and developing new drugs.

A review and comment on the current situation of 2019 novel coronavirus prevention by traditional Chinese medicine

Objective:To provide some valuable research ideas for the prevention of 2019-nCoV through reviewing and commenting the Chinese herbs in existing prevention programs of TCM.Methods:Firstly,searching the prevention and treatment programs for 2019-nCoV issued before January 29,2020.There are only three sources that can be selected in,including national and provincial health commissions,research and clinical institutes of TCM and national famous TCM doctors.Secondly,from the collections of all prevention and treatment programs,we sorted out prevention parts within Chinese herbs or patent drugs.Thirdly,we divided these TCM prevention programs into three categories and the classification is based on the two aspects of Zhengqi and pathogenic factors.Results:We classified the herbs into three parts:dispelling pathogenic factors mainly,tonifying Zhengqi with dispelling pathogenic factors and syndrome differentiation according to the two most important aspects,Zhengqi and pathogenic factors in TCM prevention theory.Reviewing the above three parts according to TCM theories and introducing some modern pharmacological researches of these herbs.Some matters needing attention were pointed out in clinical application of traditional Chinese herbs.Comments and perspectives:We made the comments on shortcomings of the present situation and look forward to what can be done later from three aspects:collection of clinical data,clinical controlled study and modern pharmacological research.

Interpretation of ancient Chinese novels-- The image-shaping

Novelist has a mission to shape the characters. The reason that Chinese classic novels have amazing artistic charm and immortal literary value ultimately lies in the diverse and distinctive characters that created by the author. From Jingwei and Kua Fu in the early myths to Jia Baoyu and Lin Daiyu in classical novels of mature period, the characters have been talked about for many years. Through the typical image, the author deduces a section of joys and sorrows to the reader, showing the bizarre society. When making interpretation of characters in the ancient novel, we should both root in the social context but also pay attention to authors＇ appraise attitude. Because contemporary readers can not be out of real background, and also be allowed to make a reasonable re-interpretation, in order to make a more accurate, objective and comprehensive grasp of the characters in classical novels.

Guidance on home rehabilitation in Chinese and Western medicine to prevent the relapse of novel coronavirus disease-19 pneumonia after recovery

Patients with novel coronavirus disease-19(COVID-19)pneumonia continue to have problems with respiratory function,physical and psychological function,the ability to perform activities of daily living,and social participation after discharge from the hospital.As such,strengthening rehabilitation treatments for discharged patients and relapse prevention after recovery are important aspects of the prevention and control of COVID-19.This paper combined the principles and practices of in Chinese and Western medicine and compiled the recommendations of both for home rehabilitation in the post-COVID-19 epidemic stage.The purpose of this paper is to facilitate the self-rehabilitation of patients with COVID-19 and to promote the prevention and control of COVID-19 at this current stage.

Novel in-frame deletion mutation c.177_179del TAC of neurofibromatosis type 1 in a Chinese 4-year-old boy with binocular blindness

Dear editor,I am Dr.Jie Peng,from the Department of Ophthalmology,Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai,China.I write to present a case report of a novel in-frame deletion mutation c.17779del TAC of neurofibromatosis type 1 in a Chinese boy with bilateral blindness.Neurofibromatosis type 1(NF1;OMIM#162200),an autosomal dominant disease,is caused by mutations in the NF1gene.The incidence of this disease is around 1 in 3500

Intellectuals in Chinese Novels at the Dawn of the 21st Century

The dawn of the 21st century saw images of intellectuals in novels change in a drastic way.Intellectuals,and those in the humanities in particular,are no longer portrayed as privileged Enlightenment thinkers or sages with Confucian ideas of salvation.In the novels that take intellectuals as their subject matters,such characters often end up involved in betrayal,self-exile,or spiritual/mortal death.This is not a historical process,nor an inevitable course for intellectuals to be sure,but it remains a legitimate question to ask why these fictional intellectuals are becoming,more often than not,new tragic heroes.Why are they becoming misfits in their society and ending up in exile,abandonment,and even death?The present paper examines different images of intellectuals and the makings of their destinies.

Contemporary Chinese Calligraphy Between Tradition and Innovation

Since the mid-1980s Chinese calligraphy art has undergone a radical change and has opened itself to experimentation. A vivid debate on CCC （Contemporary Chinese Calligraphy） （Zhongguo xiandai shufa） is involving art critics in China nowadays. WANG Dongling and the modernists think that, despite many changes and influences, we can still refer to the traditional calligraphic lexicon to describe the calligraphic production of contemporary Chinese art. They still remain deeply rooted in the signified system of Chinese writing, even if they break with the strict rules of Chinese classical aesthetic （contamination of Western elements and focus on the stylistic exploration）. WANG Nanming and the Avant-garde think that ＂contemporary calligraphy is not calligraphy yet＂： It is ＂anti-calligraphy＂, annihilates Chinese tradition, rejects the use of legible characters, experiments with new languages and new media within the idiom of international contemporary art. The result is the creation of works of art that could be assimilated to Abstract art, Abstract expressionism, Conceptual art, Performance art, Contemporary dance, Multimedia art, and even Street art. This paper aims at showing how still valid and extremely productive are both these two theoretical and creative/practical approaches to Chinese calligraphy in China nowadays. They turned the art of calligraphy into a medium for global comprehension and communication.

Analysis of diagnosis and treatment of traditional Chinese medicine for COVID-19 nucleic acid

Since the outbreak of coronavirus disease 2019(COVID-19),the author has been involved in the treatment of COVID-19 in the first line.It is found that some patients had a long viral nucleic acid negative time,and even the course of the disease lasted more than 40 days.After a thorough investigation of the root causes,it is found the four possible causes were:"Blood stasis syndrome"is difficult to remove;"Damp heat"sticky greasy;Stubborn basic diseases;weak constitution.All the patients treated with traditional Chinese medicine have turned negative,and now the typical cases were analyzed and summarized in order to provide reference for the traditional Chinese medicine treatment and scientific research of the patients with COVID-19 who were difficult to turn negative.

Preventing COVID-19 with Chinese Medicine: Concepts and Suggestions

The category of^epidemic diseases^is discussed extensively in the literature of traditional Chinese medicine,however it is often overlooked in modern Chinese medicine education precisely because population-level prevention and treatment do not fit easily into the dogma that individualized herbal formulas“based on patterns identified”is the primary mode of clinical reasoning in Chinese medicine.In the recent COVID-19 epidemic,the contingencies of treating large numbers of patients meant that it was not possible to provide“one prescription for each patient.”In fact,four categories of patients were sometimes given the same formula:mild and moderate confirmed cases,close contacts of confirmed cases,and suspected cases.The lines between prevention and treatment,along with clear demarcations between individual and population-level immunity,were blurred in the mist of the urgent imperative to provide what could reasonably be expected to be effective.Lessons from the large-scale participation of Chinese medicine in the COVID-19 public health crisis are relevant for the global community of Chinese medicine practitioners and may provide insights into how future epidemics could be addressed in the absence of effective vaccines or pharmaceuticals.

A network pharmacology approach to explore the mechanism of action of Yiqi Fumai lyophilized injection in the treatment of novel coronavirus disease

Background:Shengmai decoction,which has been included in the diagnosis and treatment of coronavirus disease 2019(COVID-19),is effective in the early treatment of patients with severe COVID-19.Yiqi Fumai lyophilized injection(YQFM)is a modern Chinese medicine preparation of the Shengmai decoction.The mechanism of its intervention at the molecular level in the severe stage of COVID-19 remains unclear.Therefore,it is necessary to investigate the mechanism of YQFM in the treatment of patients with severe COVID-19.Methods:The corresponding target genes of the main active ingredients in YQFM and COVID-19 were obtained by using multiple databases and literature retrieval.A protein-protein interaction network was constructed,and enrichment analysis of the target was performed using Cytoscape 3.8.1.Lastly,the docking of all the identified compounds with angiotensin-converting enzyme II was confirmed by applying molecular docking technology.Results:YQFM has anti-inflammatory effects on RAW267.4 macrophages.The main active compounds of YQFM are all effective anti-inflammatory agents,and these active compounds also show beneficial physiological functions,such as anti-oxidation,anti-bacterial,and anticancer activities.Gene Ontology analysis showed enrichment in the following pathways:lipopolysaccharides,interleukins,NF-kappa B,interleukin-2 and others,revealing that YQFM may play a role in the treatment of patients with severe COVID-19 through these pathways.Conclusion:YQFM has multicomponent and multitarget characteristics,and it could reduce lung injury by inhibiting inflammatory reactions,promoting antiviral activities,and regulating immunity,among other functions,to treat patients with severe COVID-19.

课程思政视域下的中国当代文学教学思考——以“十七年”时期革命战争题材小说为例

在课程思政视域下,中国当代文学的课堂教学改革具有重要意义。该课程具有鲜活的时代性,教学内容具有迷人的魅力,其中蕴含的思政元素与“中国故事”高度契合,在课程思政方面颇具优势,但同时也面临着某些教学改革的困惑。本文从中国当代文学课程特点出发,结合“十七年”时期的战争题材小说,分别从修订教学目标,优化教学内容,完善考核方式,创新教学手段等方面具体探究中国现当代文学课程思政教学改革的实践路径,以期切实提高中国当代文学课程思政教学的实效。

古典小说阐释中的“奇书”视野和“名著”视野

“奇书”视野,是晚明清初流行的一种阐释路径,其特点是把“四大奇书”的主旨纳入儒学的框架;“名著”视野,是五四以来逐渐流行的一种阐释路径,其特点是以“革命”话语阐释“四大名著”。这两种阐释路径,都有各自的历史因缘和文本依据,所以能产生巨大的影响,而它们都不能定于一尊,则是因为有以偏概全之嫌。补救的方法,是将两种视野互相参照,尽可能避免盲人摸象的失误。

“现代人”思想·长篇小说诗学·美学和历史视野——撰写中国现代长篇小说史(1922—1949年)的几点思考

撰写中国现代长篇小说史最基本也是最重要的一个思路是:以“现代人”思想为根,以长篇小说诗学为本,在美学和历史的视野下,通过对前二者融创度与完成度的探析与相关艺术问题的剖析、阐释,实现对中国现代长篇小说发展历程共时性与历时性的描述与定位,即在主潮中透视,在诗学中辨析,在审美中感悟,在时代中把握,进而清晰地勾勒出中国现代长篇小说的发展脉络、艺术得失。通过对现代长篇小说诗学艺术的深入揭示,对其中出现的一些重要的现象与问题加以理论的探讨与提升,深化中国现代长篇小说研究的问题意识,构建并拓宽中国现代长篇小说的审美认知谱系,是撰写中国现代长篇小说史的一个有效范式。