While large language models(LLMs)have made significant strides in natural language processing(NLP),they continue to face challenges in adequately addressing the intricacies of the Chinese language in certain scenarios...While large language models(LLMs)have made significant strides in natural language processing(NLP),they continue to face challenges in adequately addressing the intricacies of the Chinese language in certain scenarios.We propose a framework called Six-Writings multimodal processing(SWMP)to enable direct integration of Chinese NLP(CNLP)with morphological and semantic elements.The first part of SWMP,known as Six-Writings pictophonetic coding(SWPC),is introduced with a suitable level of granularity for radicals and components,enabling effective representation of Chinese characters and words.We conduct several experimental scenarios,including the following:(1)We establish an experimental database consisting of images and SWPC for Chinese characters,enabling dual-mode processing and matrix generation for CNLP.(2)We characterize various generative modes of Chinese words,such as thousands of Chinese idioms,used as question-and-answer(Q&A)prompt functions,facilitating analogies by SWPC.The experiments achieve 100%accuracy in answering all questions in the Chinese morphological data set(CA8-Mor-10177).(3)A fine-tuning mechanism is proposed to refine word embedding results using SWPC,resulting in an average relative error of≤25%for 39.37%of the questions in the Chinese wOrd Similarity data set(COS960).The results demonstrate that SWMP/SWPC methods effectively capture the distinctive features of Chinese and offer a promising mechanism to enhance CNLP with better efficiency.展开更多
The exption of Chinese natural language processing(NLP)has stimulated research in the broader NLP domain.However,existing large language models have limitations in comprehending and reasoning in Chinese.This paper add...The exption of Chinese natural language processing(NLP)has stimulated research in the broader NLP domain.However,existing large language models have limitations in comprehending and reasoning in Chinese.This paper addresses these limitations by enhancing Chinese language models comprehension and reasoning capabilities while minimizing resource requirements.We propose LLaMA-LoRA,a neural prompt engineering framework that builds upon the LLaMA-13B model and incorporates the Low-Rank Adaptation(LoRA)of Large Language Models technique for refinement.Chain-of-Thought(CoT)are crucial for generating intermediate reasoning chains in language models,but their effectiveness can be limited by isolated language patterns.Erroneous reasoning resulting from conventional prompts negatively impacts model performance.Automatic prompts are introduced to encourage reasoning chain generation and accurate answer inference.Training the model with an extensive corpus of Chinese CoT data enhances its comprehension and reasoning abilities.The LLaMA-LoRA model demonstrates exceptional performance across numerous Chinese language tasks,surpassing benchmark performance achieved by related language models such as GPT-3.5,Chat-GLM,and OpenAssistant,delivering accurate,comprehensive,and professional answers.The availability of our open-source model code facilitates further research in the field of Chinese text logical reasoning thinking chains.展开更多
The identity of Eastern and Western cultures should include aspects such as its concepts of societal development and science and technology.Though this is related to issues like history of the culture and regional cul...The identity of Eastern and Western cultures should include aspects such as its concepts of societal development and science and technology.Though this is related to issues like history of the culture and regional cultural psychologies,the essence lies in the identity of social values at its core.展开更多
Objective To establish an objective method for evaluating the intrinsic characteristics between cold and hot nature of Chinese materia medica (CMM) through the different effects of Mahuang decoction (MHD) and Maxing S...Objective To establish an objective method for evaluating the intrinsic characteristics between cold and hot nature of Chinese materia medica (CMM) through the different effects of Mahuang decoction (MHD) and Maxing Shigan decoction (MSD) on animal temperature tropism. Methods The equipment with cold/hot pads was used to investigate the variety of the temperature tropism between two groups of mice treated by MHD and MSD, respectively. Meanwhile, the activities of adenosine triphosphatase (ATPase), superoxide dismutase, succinate dehydrogenase, and malondialdehyde were measured. Results After treated by MHD, the macroscopic behavioral index of remaining rate on warm pad (40 ℃ ) of mice decreased significantly (P < 0.05), suggesting the enhancement of cold tropism, meanwhile, the internal indices of ATPase activity and oxygen consuming volume increased significantly (P < 0.05), suggesting the enhancement of energy metabolism. On the other hand, the above-mentioned indices in MSD group changed on the inverse way. Conclusion The relative drug nature of MHD and MSD revealed in this study is consistent with the theoretical prognostication or definition. It indicates that the internal cold and hot nature of CMM could be reflected in ethological way on the changes of animal temperature tropism which might be internally regulated by body energy metabolism.展开更多
Chemotherapy is still the effective strategy for treating cancer.It is important to explore anticancer agents from Traditional Chinese Medicine and Natural products.Different cancer cell lines were included in our res...Chemotherapy is still the effective strategy for treating cancer.It is important to explore anticancer agents from Traditional Chinese Medicine and Natural products.Different cancer cell lines were included in our research,such as HL60,K562,K562/ADR,KB,KBv200 cells.Cell growth inhibition assay,Annexin V-FITC/PI double-staining assay,measurement of reactive展开更多
出版专刊/专栏已成为国内外科技期刊争取优质稿件、提升期刊影响力的重要措施。但近年来,国内外撤稿事件中专刊/专栏文章屡见不鲜,表明部分专刊/专栏的约组事与愿违,忽略了组约稿件学术质量的把控。本研究在分析近年来专刊/专栏撤稿经...出版专刊/专栏已成为国内外科技期刊争取优质稿件、提升期刊影响力的重要措施。但近年来,国内外撤稿事件中专刊/专栏文章屡见不鲜,表明部分专刊/专栏的约组事与愿违,忽略了组约稿件学术质量的把控。本研究在分析近年来专刊/专栏撤稿经典案例的基础上,进一步比较分析国内外2种期刊PNAS和《Chinese Journal of Natural Medicines--》专刊/专栏相对于同期其他自由投稿论文的影响力,据此提出提升专刊/专栏质量的相关建议:核实客座编辑身份,慎重选择客座编辑;加强评审环节,避免"既当运动员又当裁判";稿件面前一视同仁,不迷信权威;合理安排专刊/专栏出版频率,保证学术质量。展开更多
Objective:To explore the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction(麻黄汤,MHD) and Maxing Shigan Decoction(麻杏石甘汤,MXSGD),both categorized formulas but with differe...Objective:To explore the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction(麻黄汤,MHD) and Maxing Shigan Decoction(麻杏石甘汤,MXSGD),both categorized formulas but with different hot/cold natures.Methods:Oxygen consumption of mice was determined among three groups:MHD,MXSGD and the control;a cold-hot pad differentiating assay was used to observe the variability of temperature tropism among the groups of mice which was treated with MHD,MXSGD,and their compositions. Meanwhile,the total anti-oxidant capability(T-AOC) activity were detected.Results:After administration of MHD, the mice showed increased oxygen consumption(P0.01).Compared with MHD group,the remaining rate of MXSGD mice on the hot pad was found to be significantly increased with the cold-hot pad differentiating assay (P0.05).There was no significant difference(P0.05) among the remaining rates of MXSGD,MXSGD with high dose Gypsum Fibrosum(MXHGF) group,and MXSGD with low dose Gypsum Fibrosum(MXLGF) group mice.Compared with the MHD group,T-AOC activity of the mice in the Consensus Compositons group was significantly decreased(P=0.0494).Compared with the MXSGD group,T-AOC activity of Gypsum Fibrosum (GF) group was increased significantly(P=0.0013).Conclusions:The differences in cold and hot nature could be represented objectively between MHD with a hot nature and MXSGD with a cold nature.The reason may be the Gypsum Fibrosum which decreased the efficacy of the consensus compositions.However,increasing or decreasing the dose of Gypsum Fibrosum will not change the cold and hot nature of MXSGD.展开更多
基金Project partially supported by the Brazilian National Council for Scientific and Technological Development(CNPq)(No.309545/2021-8)。
文摘While large language models(LLMs)have made significant strides in natural language processing(NLP),they continue to face challenges in adequately addressing the intricacies of the Chinese language in certain scenarios.We propose a framework called Six-Writings multimodal processing(SWMP)to enable direct integration of Chinese NLP(CNLP)with morphological and semantic elements.The first part of SWMP,known as Six-Writings pictophonetic coding(SWPC),is introduced with a suitable level of granularity for radicals and components,enabling effective representation of Chinese characters and words.We conduct several experimental scenarios,including the following:(1)We establish an experimental database consisting of images and SWPC for Chinese characters,enabling dual-mode processing and matrix generation for CNLP.(2)We characterize various generative modes of Chinese words,such as thousands of Chinese idioms,used as question-and-answer(Q&A)prompt functions,facilitating analogies by SWPC.The experiments achieve 100%accuracy in answering all questions in the Chinese morphological data set(CA8-Mor-10177).(3)A fine-tuning mechanism is proposed to refine word embedding results using SWPC,resulting in an average relative error of≤25%for 39.37%of the questions in the Chinese wOrd Similarity data set(COS960).The results demonstrate that SWMP/SWPC methods effectively capture the distinctive features of Chinese and offer a promising mechanism to enhance CNLP with better efficiency.
基金supported by the the Science and Technology Program of Sichuan Province(Grant no.2023YFS0424)the"Open bidding for selecting the best candidates"Science and Technology Project of Chengdu(Grant no.2023-JB00-00020-GX)the National Natural Science Foundation(Grant nos.61902324,11426179,and 61872298).
文摘The exption of Chinese natural language processing(NLP)has stimulated research in the broader NLP domain.However,existing large language models have limitations in comprehending and reasoning in Chinese.This paper addresses these limitations by enhancing Chinese language models comprehension and reasoning capabilities while minimizing resource requirements.We propose LLaMA-LoRA,a neural prompt engineering framework that builds upon the LLaMA-13B model and incorporates the Low-Rank Adaptation(LoRA)of Large Language Models technique for refinement.Chain-of-Thought(CoT)are crucial for generating intermediate reasoning chains in language models,but their effectiveness can be limited by isolated language patterns.Erroneous reasoning resulting from conventional prompts negatively impacts model performance.Automatic prompts are introduced to encourage reasoning chain generation and accurate answer inference.Training the model with an extensive corpus of Chinese CoT data enhances its comprehension and reasoning abilities.The LLaMA-LoRA model demonstrates exceptional performance across numerous Chinese language tasks,surpassing benchmark performance achieved by related language models such as GPT-3.5,Chat-GLM,and OpenAssistant,delivering accurate,comprehensive,and professional answers.The availability of our open-source model code facilitates further research in the field of Chinese text logical reasoning thinking chains.
文摘The identity of Eastern and Western cultures should include aspects such as its concepts of societal development and science and technology.Though this is related to issues like history of the culture and regional cultural psychologies,the essence lies in the identity of social values at its core.
基金National Basic Research Program of China ("973" Program) (2007CB5126072006CB504703)National Science Fund for Distinguished Young Scholars (30625042)
文摘Objective To establish an objective method for evaluating the intrinsic characteristics between cold and hot nature of Chinese materia medica (CMM) through the different effects of Mahuang decoction (MHD) and Maxing Shigan decoction (MSD) on animal temperature tropism. Methods The equipment with cold/hot pads was used to investigate the variety of the temperature tropism between two groups of mice treated by MHD and MSD, respectively. Meanwhile, the activities of adenosine triphosphatase (ATPase), superoxide dismutase, succinate dehydrogenase, and malondialdehyde were measured. Results After treated by MHD, the macroscopic behavioral index of remaining rate on warm pad (40 ℃ ) of mice decreased significantly (P < 0.05), suggesting the enhancement of cold tropism, meanwhile, the internal indices of ATPase activity and oxygen consuming volume increased significantly (P < 0.05), suggesting the enhancement of energy metabolism. On the other hand, the above-mentioned indices in MSD group changed on the inverse way. Conclusion The relative drug nature of MHD and MSD revealed in this study is consistent with the theoretical prognostication or definition. It indicates that the internal cold and hot nature of CMM could be reflected in ethological way on the changes of animal temperature tropism which might be internally regulated by body energy metabolism.
文摘Chemotherapy is still the effective strategy for treating cancer.It is important to explore anticancer agents from Traditional Chinese Medicine and Natural products.Different cancer cell lines were included in our research,such as HL60,K562,K562/ADR,KB,KBv200 cells.Cell growth inhibition assay,Annexin V-FITC/PI double-staining assay,measurement of reactive
文摘出版专刊/专栏已成为国内外科技期刊争取优质稿件、提升期刊影响力的重要措施。但近年来,国内外撤稿事件中专刊/专栏文章屡见不鲜,表明部分专刊/专栏的约组事与愿违,忽略了组约稿件学术质量的把控。本研究在分析近年来专刊/专栏撤稿经典案例的基础上,进一步比较分析国内外2种期刊PNAS和《Chinese Journal of Natural Medicines--》专刊/专栏相对于同期其他自由投稿论文的影响力,据此提出提升专刊/专栏质量的相关建议:核实客座编辑身份,慎重选择客座编辑;加强评审环节,避免"既当运动员又当裁判";稿件面前一视同仁,不迷信权威;合理安排专刊/专栏出版频率,保证学术质量。
基金Supported by the Major State Basic Research Development Program of China(973 Program,No.2007CB512607)the National Science Fund for Distinguished Young Scholars (No.30625042)National Science and Technology Major Project of the Ministry of Science and Technology of China(No. 2009ZX10005-017)
文摘Objective:To explore the complex prescription compatibility law of the cold and hot nature of Mahuang Decoction(麻黄汤,MHD) and Maxing Shigan Decoction(麻杏石甘汤,MXSGD),both categorized formulas but with different hot/cold natures.Methods:Oxygen consumption of mice was determined among three groups:MHD,MXSGD and the control;a cold-hot pad differentiating assay was used to observe the variability of temperature tropism among the groups of mice which was treated with MHD,MXSGD,and their compositions. Meanwhile,the total anti-oxidant capability(T-AOC) activity were detected.Results:After administration of MHD, the mice showed increased oxygen consumption(P0.01).Compared with MHD group,the remaining rate of MXSGD mice on the hot pad was found to be significantly increased with the cold-hot pad differentiating assay (P0.05).There was no significant difference(P0.05) among the remaining rates of MXSGD,MXSGD with high dose Gypsum Fibrosum(MXHGF) group,and MXSGD with low dose Gypsum Fibrosum(MXLGF) group mice.Compared with the MHD group,T-AOC activity of the mice in the Consensus Compositons group was significantly decreased(P=0.0494).Compared with the MXSGD group,T-AOC activity of Gypsum Fibrosum (GF) group was increased significantly(P=0.0013).Conclusions:The differences in cold and hot nature could be represented objectively between MHD with a hot nature and MXSGD with a cold nature.The reason may be the Gypsum Fibrosum which decreased the efficacy of the consensus compositions.However,increasing or decreasing the dose of Gypsum Fibrosum will not change the cold and hot nature of MXSGD.