Objective: To study the rule of syndrome differentiation in the patients with thoracic diseases at perioperation stage. Methods: A standard was created referring to the related literature, and it was applied to diff...Objective: To study the rule of syndrome differentiation in the patients with thoracic diseases at perioperation stage. Methods: A standard was created referring to the related literature, and it was applied to differentiate the Chinese medicine syndrome in 150 patients before and three days after thoracic operation. Results: Before operation, Chinese medicine syndromes were as differentiated as phlegm type in 45.3%, blood stasis type in 17.3%, and qi-stagnancy type in 16.0%. The patients with asthenia syndrome markedly increased after operation, accounting for 34.0% (51 patients, including qi-, yin-, and blood-deficiency syndromes). The most frequently seen intermixed syndromes were qi-deficiency with phlegm-stasis syndrome and Pi (脾)-deficiency with phlegm-dampness syndrome. The intermixed syndromes revealed in 37.5% and 42.0% of the patients before and after operation, respectively. Conclusion: The syndrome in the patients with thoracic disease before operation was mostly the excessive syndrome, mainly the phlegm syndrome type; at postoperation stage, Chinese medicine syndrome in patients become asthenia in essence with excessive superficiality, which is mostly revealed as Pi-deficiency with phlegm-dampness.展开更多
The operation of the biliary system is usually employed for liver, gallbladder or pancreatic diseases. Most benign cases are cholelithiasisinduced cholecystitis and choledochitis, while malignant ones mainly include g...The operation of the biliary system is usually employed for liver, gallbladder or pancreatic diseases. Most benign cases are cholelithiasisinduced cholecystitis and choledochitis, while malignant ones mainly include gallbladder cancers, cholangiocarcinoma orcarcinoma of the head of the pancreas.展开更多
BACKGROUND: Pulse wave analysis(PWA) quantifies the phenomenon of pulse waveform propagation in patients with cardiovascular diseases, whereas pulse image analysis(PIA) is a subjective examination in traditional ...BACKGROUND: Pulse wave analysis(PWA) quantifies the phenomenon of pulse waveform propagation in patients with cardiovascular diseases, whereas pulse image analysis(PIA) is a subjective examination in traditional Chinese medicine. OBJECTIVE: This study evaluated the association of PIA with PWA and hemodynamics in patients with hypertension. DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS: This observational, cross-sectional study enrolled 45 patients(26 men,(55.2± 10.3) years, systolic blood pressure(155± 28) mm Hg, diastolic blood pressure(93± 17) mm Hg) for assessment of clinical and laboratorial data. MAIN OUTCOME MEASURES: Primary outcomes comprised: pattern differentiation based on an automated method; PIA at the radial artery using the ‘simultaneous pressing' method for identification of factors such as strength(strong/weak), depth(superficial/deep), and speed(fast/moderate/slow); and PWA at the same artery using a noninvasive system. RESULTS: Significant multivariate main effects were observed for depth(l=0.648, F_(5,29)=3.149, P=0.022, h^2 =0.352), strength(l=0.608, F_(5,29) =3.736, P=0.010, h^2 =0.392), and speed(l=0.535, F_(5,29) =5.302, P=0.002, h^2 =0.465). General effects comprised high values of PWA and blood pressure for superficial, strong, and fast pulse images. A strong pulse was found for pulse pressure ≥ 62.5 mm Hg and systolic blood pressure ≥ 149.5 mm Hg, whereas a superficial pulse was found for heart rate ≥ 58.25 beats/min; a fast pulse was found for heart rate ≥ 69.6 beats/min and pulse wave velocity ≥ 9.185 m/s. CONCLUSION: Associations were explained by La Place's law, arterial remodeling in hypertension, alongside the traditional criterion for classifying speed in pulse images. PIA is associated with PWA and hemodynamics in patients with hypertension. Systolic and pulse pressures, heart rate, and pulse wave velocity are quantitative variables that have information to describe the qualitative pulse images such as strength, depth and speed.展开更多
Objective: To observe the effects of Yunqi decoction (匀气汤, YQD) on both esophageal mucosal morphology and esophageal motility in patients with reflux esophagitis (RE). Methods: According to syndrome differentiation...Objective: To observe the effects of Yunqi decoction (匀气汤, YQD) on both esophageal mucosal morphology and esophageal motility in patients with reflux esophagitis (RE). Methods: According to syndrome differentiation of traditional Chinese medicine (TCM), 42 RE patients were divided into three groups fdisharmony of Liver and Stomach (group D), Deficiency-Cold of Spleen and Stomach (Group DC), Heat Syndrome caused by stagnation of Liver Qi (Group H). No. Ⅰ, Ⅱ, Ⅲ of YQD were taken respectively for 4 weeks.Before and after treatment scores of typical symptoms were collected, gastroscopy was performed and esophagealmotility were measured. Results: (1 ) The symptom remission rate was 81. 1 %, there were significant differences between the group DC with group D and group H (P< 0. 01 ). (2) The esophageal mucosal healing ratewas 61. 9 %, the effective rate was 90. 5 %, and the ineffective rate was 9. 5 %. There were not significant differences of effective rate among the three groups (P > 0. 05). (3) The changes of esophageal motility: Loweresophageal sphincter pressure (LESP) and average peristaltic pressure (APP) of group D were obviously higherthan before treatment (P < 0. 05), LESP, gastro--esophageal barrier pressure (GEBP) and peristaltic conductspeed (PCS) of group DC were remarkably higher (P < 0. 05). GEBP of group H was improved (P < 0. 05 ).Conclusions: YQD has a good therapeutic effect. It's not only resolving reflux esophageal symptoms, healingesophageal mucosa, but also improving esophageal motile function.展开更多
基金Supported by Health Bureau of Zhejiang Province(No. 2008CA081)
文摘Objective: To study the rule of syndrome differentiation in the patients with thoracic diseases at perioperation stage. Methods: A standard was created referring to the related literature, and it was applied to differentiate the Chinese medicine syndrome in 150 patients before and three days after thoracic operation. Results: Before operation, Chinese medicine syndromes were as differentiated as phlegm type in 45.3%, blood stasis type in 17.3%, and qi-stagnancy type in 16.0%. The patients with asthenia syndrome markedly increased after operation, accounting for 34.0% (51 patients, including qi-, yin-, and blood-deficiency syndromes). The most frequently seen intermixed syndromes were qi-deficiency with phlegm-stasis syndrome and Pi (脾)-deficiency with phlegm-dampness syndrome. The intermixed syndromes revealed in 37.5% and 42.0% of the patients before and after operation, respectively. Conclusion: The syndrome in the patients with thoracic disease before operation was mostly the excessive syndrome, mainly the phlegm syndrome type; at postoperation stage, Chinese medicine syndrome in patients become asthenia in essence with excessive superficiality, which is mostly revealed as Pi-deficiency with phlegm-dampness.
文摘The operation of the biliary system is usually employed for liver, gallbladder or pancreatic diseases. Most benign cases are cholelithiasisinduced cholecystitis and choledochitis, while malignant ones mainly include gallbladder cancers, cholangiocarcinoma orcarcinoma of the head of the pancreas.
基金supported by the grant from the Fundacao Carlos Chagas Filho de AmparoaPesquisa do Estado do Rio de Janeiro(FAPERJ)
文摘BACKGROUND: Pulse wave analysis(PWA) quantifies the phenomenon of pulse waveform propagation in patients with cardiovascular diseases, whereas pulse image analysis(PIA) is a subjective examination in traditional Chinese medicine. OBJECTIVE: This study evaluated the association of PIA with PWA and hemodynamics in patients with hypertension. DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS: This observational, cross-sectional study enrolled 45 patients(26 men,(55.2± 10.3) years, systolic blood pressure(155± 28) mm Hg, diastolic blood pressure(93± 17) mm Hg) for assessment of clinical and laboratorial data. MAIN OUTCOME MEASURES: Primary outcomes comprised: pattern differentiation based on an automated method; PIA at the radial artery using the ‘simultaneous pressing' method for identification of factors such as strength(strong/weak), depth(superficial/deep), and speed(fast/moderate/slow); and PWA at the same artery using a noninvasive system. RESULTS: Significant multivariate main effects were observed for depth(l=0.648, F_(5,29)=3.149, P=0.022, h^2 =0.352), strength(l=0.608, F_(5,29) =3.736, P=0.010, h^2 =0.392), and speed(l=0.535, F_(5,29) =5.302, P=0.002, h^2 =0.465). General effects comprised high values of PWA and blood pressure for superficial, strong, and fast pulse images. A strong pulse was found for pulse pressure ≥ 62.5 mm Hg and systolic blood pressure ≥ 149.5 mm Hg, whereas a superficial pulse was found for heart rate ≥ 58.25 beats/min; a fast pulse was found for heart rate ≥ 69.6 beats/min and pulse wave velocity ≥ 9.185 m/s. CONCLUSION: Associations were explained by La Place's law, arterial remodeling in hypertension, alongside the traditional criterion for classifying speed in pulse images. PIA is associated with PWA and hemodynamics in patients with hypertension. Systolic and pulse pressures, heart rate, and pulse wave velocity are quantitative variables that have information to describe the qualitative pulse images such as strength, depth and speed.
文摘Objective: To observe the effects of Yunqi decoction (匀气汤, YQD) on both esophageal mucosal morphology and esophageal motility in patients with reflux esophagitis (RE). Methods: According to syndrome differentiation of traditional Chinese medicine (TCM), 42 RE patients were divided into three groups fdisharmony of Liver and Stomach (group D), Deficiency-Cold of Spleen and Stomach (Group DC), Heat Syndrome caused by stagnation of Liver Qi (Group H). No. Ⅰ, Ⅱ, Ⅲ of YQD were taken respectively for 4 weeks.Before and after treatment scores of typical symptoms were collected, gastroscopy was performed and esophagealmotility were measured. Results: (1 ) The symptom remission rate was 81. 1 %, there were significant differences between the group DC with group D and group H (P< 0. 01 ). (2) The esophageal mucosal healing ratewas 61. 9 %, the effective rate was 90. 5 %, and the ineffective rate was 9. 5 %. There were not significant differences of effective rate among the three groups (P > 0. 05). (3) The changes of esophageal motility: Loweresophageal sphincter pressure (LESP) and average peristaltic pressure (APP) of group D were obviously higherthan before treatment (P < 0. 05), LESP, gastro--esophageal barrier pressure (GEBP) and peristaltic conductspeed (PCS) of group DC were remarkably higher (P < 0. 05). GEBP of group H was improved (P < 0. 05 ).Conclusions: YQD has a good therapeutic effect. It's not only resolving reflux esophageal symptoms, healingesophageal mucosa, but also improving esophageal motile function.