A spectrophotometric method for the determination of chlorhexidine acetate is described. The reaction between chlorhexidine acetate and chloranil took place in an alcohol-acetone solution at room temperature. The comp...A spectrophotometric method for the determination of chlorhexidine acetate is described. The reaction between chlorhexidine acetate and chloranil took place in an alcohol-acetone solution at room temperature. The composition of the charge transfer complex is 1:2. Beer's law is obeyed in the concentration range of 15–270 μg·mL?1 with correlation coefficient 0.9995. The apparent molar absorptivity is 2.21 × 103 L·mol?1·cm?1 at 412 nm. The method is accurate (with a recovery af 100 ± 1.6% ) and precise (RSD =1.0%). It was successfully applied to determine chlorhexidine acetate in suppository or disinfectant solution.展开更多
基金Project (No. 29392601) supposal by the National Natural Science Foundation of China
文摘A spectrophotometric method for the determination of chlorhexidine acetate is described. The reaction between chlorhexidine acetate and chloranil took place in an alcohol-acetone solution at room temperature. The composition of the charge transfer complex is 1:2. Beer's law is obeyed in the concentration range of 15–270 μg·mL?1 with correlation coefficient 0.9995. The apparent molar absorptivity is 2.21 × 103 L·mol?1·cm?1 at 412 nm. The method is accurate (with a recovery af 100 ± 1.6% ) and precise (RSD =1.0%). It was successfully applied to determine chlorhexidine acetate in suppository or disinfectant solution.
