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The Polycomb Complex PRC1:Composition and Function in Plants 被引量:6
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作者 Anne Molitor Wen-Hui Shen 《Journal of Genetics and Genomics》 SCIE CAS CSCD 2013年第5期231-238,共8页
Polycomb group(PcG) proteins are crucial epigenetic regulators conferring transcriptional memory to cell lineages.They assemble into multi-protein complexes,e.g.,Polycomb Repressive Complex 1 and 2(PRC1,PRC2),whic... Polycomb group(PcG) proteins are crucial epigenetic regulators conferring transcriptional memory to cell lineages.They assemble into multi-protein complexes,e.g.,Polycomb Repressive Complex 1 and 2(PRC1,PRC2),which are thought to act in a sequential manner to stably maintain gene repression.PRC2 induces histone H3 lysine 27(H3K27) trimethylation(H3K27me3),which is subsequently read by PRCl that further catalyzes H2A monoubiquitination(H2Aub1),creating a transcriptional silent chromatin conformation.PRC2 components are conserved in plants and have been extensively characterized in Arabidopsis.In contrast,PRCl composition and function are more diverged between animals and plants.Only more recently,PRC1 existence in plants has been documented.Here we review the aspects of plant specific and conserved PRC1 and highlight critical roles of PRC1 components in seed embryonic trait determinacy,shoot stem cell fate determinacy,and flower development in Arabidopsis. 展开更多
关键词 Epigenetics chromatin histone modifications Polycomb PRC1 Arabidopsis development
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