As an important branch of medicine, Traditional Chinese Medicine(TCM) has been applied for the treatment of diseases for thousands of years in China and other countries in East Asia. The Chinese Pharmacopoeia(ChP) is ...As an important branch of medicine, Traditional Chinese Medicine(TCM) has been applied for the treatment of diseases for thousands of years in China and other countries in East Asia. The Chinese Pharmacopoeia(ChP) is a drug code formulated by the Chinese government, and it includes a special volume for the monographs of TCM, which plays an important role in ensuring the quality of drugs. The use of quality control technology has always been a complex and important factor in TCM. Owing to the chemical diversity of TCM, chromatography technology has been proven to be a comprehensive strategy for the assessment of the overall quality of TCM and has become the main analytical method in the ChP.This article provides an overview of the classical and modern chromatographic technologies applied in the ChP, and summarizes the advantages and disadvantages of each technique in the TCM monographs.In 2020, the new edition of the Ch P(the 2020 edition) has been implemented at the end of 2020. This paper also contains a brief introduction about the application of chromatographic technologies in the new edition of the ChP.展开更多
In this study, whole-oil gas chromatographic fingerprint analyses were performed on oils from the Es3^3 reservoir in the Liubei area of the Nanpu Sag. The gas chromatographic peaks of cyclic and branched alkanes with ...In this study, whole-oil gas chromatographic fingerprint analyses were performed on oils from the Es3^3 reservoir in the Liubei area of the Nanpu Sag. The gas chromatographic peaks of cyclic and branched alkanes with relatively high resolution from nCl0 to nC25 were selected to establish a database of whole-oil gas chromatographic peak height ratio fingerprints. Reservoir fluid connectivity was identified by using clustering analysis. This method can reflect the gas chromatography fingerprint information accurately and entirely, and avoid the one-sidedness of the star diagram method which only selects several fixed gas chromatographic peaks.展开更多
The homochiral compounds play an important role in human health and pharmaceutical industry.Currently,the chromatographic enantioseparation has become one of the most effective and practical approach to obtain pure en...The homochiral compounds play an important role in human health and pharmaceutical industry.Currently,the chromatographic enantioseparation has become one of the most effective and practical approach to obtain pure enantiomers.Herein,the exploration of advanced materials,using as chromatographic chiral stationary phases for racemic separation,has attracted great attention.Thanks to their high enantioselectivity and controllable synthesis,the emerging chiral metal-organic frameworks (CMOFs)have been widely studied as the stationary phase in chromatographic technology.In this review,we will summarize the principles of synthetic strategies and mechanism of chiral microenvironment.In particular,the recent progress and research hotspot of CMOFs regarding as the chiral stationary phases in gas chromatography (GC),high-performance liquid chromatography (HPLC),and capillary electrochromatography (CEC),are elucidated systematically according to the published work.Last but not the least,we also highlight the challenges and perspectives of rational design of CMOFs,as well as their corresponding racemic separation.We envision that the review will provide a further understanding of CMOFs and facilitate the development of chromatographic enantioselective applications.展开更多
文摘As an important branch of medicine, Traditional Chinese Medicine(TCM) has been applied for the treatment of diseases for thousands of years in China and other countries in East Asia. The Chinese Pharmacopoeia(ChP) is a drug code formulated by the Chinese government, and it includes a special volume for the monographs of TCM, which plays an important role in ensuring the quality of drugs. The use of quality control technology has always been a complex and important factor in TCM. Owing to the chemical diversity of TCM, chromatography technology has been proven to be a comprehensive strategy for the assessment of the overall quality of TCM and has become the main analytical method in the ChP.This article provides an overview of the classical and modern chromatographic technologies applied in the ChP, and summarizes the advantages and disadvantages of each technique in the TCM monographs.In 2020, the new edition of the Ch P(the 2020 edition) has been implemented at the end of 2020. This paper also contains a brief introduction about the application of chromatographic technologies in the new edition of the ChP.
基金funded by Shandong Provincial Key Laboratory of Depositional Mineralization & Sedimentary Minerals (Project DMSM201009)Key Laboratory of Tectonics and Petroleum Resources (China University of Geosciences), Ministry of Education, China (Project TPR-2010-29)
文摘In this study, whole-oil gas chromatographic fingerprint analyses were performed on oils from the Es3^3 reservoir in the Liubei area of the Nanpu Sag. The gas chromatographic peaks of cyclic and branched alkanes with relatively high resolution from nCl0 to nC25 were selected to establish a database of whole-oil gas chromatographic peak height ratio fingerprints. Reservoir fluid connectivity was identified by using clustering analysis. This method can reflect the gas chromatography fingerprint information accurately and entirely, and avoid the one-sidedness of the star diagram method which only selects several fixed gas chromatographic peaks.
基金supported by the Science and Technology Project of Education Department of Jiangxi Province (No.GJJ201249)。
文摘The homochiral compounds play an important role in human health and pharmaceutical industry.Currently,the chromatographic enantioseparation has become one of the most effective and practical approach to obtain pure enantiomers.Herein,the exploration of advanced materials,using as chromatographic chiral stationary phases for racemic separation,has attracted great attention.Thanks to their high enantioselectivity and controllable synthesis,the emerging chiral metal-organic frameworks (CMOFs)have been widely studied as the stationary phase in chromatographic technology.In this review,we will summarize the principles of synthetic strategies and mechanism of chiral microenvironment.In particular,the recent progress and research hotspot of CMOFs regarding as the chiral stationary phases in gas chromatography (GC),high-performance liquid chromatography (HPLC),and capillary electrochromatography (CEC),are elucidated systematically according to the published work.Last but not the least,we also highlight the challenges and perspectives of rational design of CMOFs,as well as their corresponding racemic separation.We envision that the review will provide a further understanding of CMOFs and facilitate the development of chromatographic enantioselective applications.
