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Interpeduncular cistern intrathecal targeted drug delivery for intractable postherpetic neuralgia: A case report 被引量:2
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作者 Feng Fu Xian-Feng Jiang +4 位作者 Jing-Jing Wang Lei Gong Chen Yun Hong-Tao Sun Feng-Wu Tang 《World Journal of Clinical Cases》 SCIE 2023年第30期7380-7385,共6页
BACKGROUND Intractable postherpetic neuralgia(PHN)can be difficult to manage even with aggressive multimodal therapies.Patients who experience uncontrolled refractory cranial PHN despite conservative treatment may ben... BACKGROUND Intractable postherpetic neuralgia(PHN)can be difficult to manage even with aggressive multimodal therapies.Patients who experience uncontrolled refractory cranial PHN despite conservative treatment may benefit from an intrathecal drug delivery system(IDDS).For craniofacial neuropathic pain,the traditional approach has been to place the intrathecal catheter tip below the level of the cranial nerve root entry zones,which may lead to insufficient analgesia.CASE SUMMARY We describe a 69-year-old man with a 1-year history of PHN after developing a vesicular rash in the ophthalmic division of cranial nerve V(trigeminal nerve)distribution.The pain was rated 7-8 at rest and 9-10 at breakthrough pain(BTP)on a numeric rating scale.Despite receiving aggressive multimodal therapies including large doses of oral analgesics(gabapentin 150 mg q12 h,oxycodone 5 mg/acetaminophen 325 mg q6 h,and lidocaine 5%patch 700 mg q12 h)and sphenopalatine ganglion block,there was no relief of pain.Subsequently,the patient elected to have an implantable IDDS with the catheter tip placed at the interpeduncular cistern.The frequency of BTP episodes decreased.The patient’s continuous daily dose was adjusted to 0.032 mg/d after 3 mo of follow-up and stopped 5 mo later.He did not report pain or other discomfort at outpatient follow-up 6 mo and 1 year after stopping intracisternal hydromorphone.CONCLUSION The use of interpeduncular cistern intrathecal infusion with low-dose hydromorphone by IDDS may be effective for severe craniofacial PHN. 展开更多
关键词 Postherpetic neuralgia Intrathecal drug delivery Interpeduncular cistern Craniofacial pain OPIOIDS Case report
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Suitability and Sustainability of Rainwater QualityMonitoring System in Cistern for Domestic Use
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作者 Kenedy A.Greyson 《Journal on Internet of Things》 2023年第1期1-11,共11页
Rainwater harvesting(RWH)systems have been the source of domestic water for many years and still becoming essential in many communities of developing countries.However,due to various reasons,there are several sources ... Rainwater harvesting(RWH)systems have been the source of domestic water for many years and still becoming essential in many communities of developing countries.However,due to various reasons,there are several sources of contamination in the rainwater cistern systems.Dissolved chemicals from the roofing,storage,and conveyance materials,together with the suspended particulate matter from the airborne,are examples of water contamination.In this work,the water quality monitoring system has been designed and implemented.Chemical and physical parameters of water samples were collected from three locations using a data acquisition(DAQ)system and rainwater quality was analyzed using Water Pollution Index(WPI).Results obtained from three locations have been presented. 展开更多
关键词 cistern DAQ system monitoring system RWH system water pollution WPI
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Rainwater quality assessment of a solidified soil cistern using new construction technology
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作者 许秀泉 高建恩 《Journal of Southeast University(English Edition)》 EI CAS 2014年第2期240-245,共6页
A plastic mixture construction technology using MBER (material becoming earth into rock) soil stabilizer is introduced and the water quality of a solidified soil cistern using the technology is analyzed. Rainwater w... A plastic mixture construction technology using MBER (material becoming earth into rock) soil stabilizer is introduced and the water quality of a solidified soil cistern using the technology is analyzed. Rainwater was harvested in July, 2012. Water quality of runoff and cistern water after storage was measured, including turbidity, chemical oxygen demand (COD), total nitrogen, nitrate, and ammonia. Results show that pollutant concentrations in runoff decreased with time, indicating that runoff in the early time should be removed. Nitrate concentrations in cistern water increased after storage, while the remaining parameters decreased. Measured pollutant concentrations did not exceed the limit according to the standard for drinking water in China. It can be concluded that the solidified soil cistern with plastic mixture construction technology can provide available water for domestic use. 展开更多
关键词 soil stabilizer cistern construction technology water quality
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Suprasellar cistern tuberculoma presenting as unilateral ocular motility disorder and ptosis:A case report
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作者 Bi-Bo Zhao Chao Tian +1 位作者 Le-Jun Fu Xue-Bin Zhang 《World Journal of Clinical Cases》 SCIE 2022年第14期4691-4697,共7页
BACKGROUND Intracranial tuberculoma is a rare and serious type of tuberculosis,which mostly occurs in the frontoparietal and cerebellar hemispheres,with predominance in the gray-white matter junction area,while tuberc... BACKGROUND Intracranial tuberculoma is a rare and serious type of tuberculosis,which mostly occurs in the frontoparietal and cerebellar hemispheres,with predominance in the gray-white matter junction area,while tuberculomas only in the cistern are extremely rare with only a few reported cases in the literature.We describe a unique case of isolated tuberculoma in the suprasellar cistern,with only right ocular motility disorder and upper eyelid ptosis.CASE SUMMARY A 5-year-old boy without any medical history presented with right ocular motility disorder and upper eyelid ptosis one month ago.He had no history of fever,headache,vomiting,convulsions,or limb weakness.Neurological examination showed right third cranial nerve palsy with restrictions of eye movements and ptosis,pupil dilation and negative light reflex.Imaging suggested a spaceoccupying lesion in the suprasellar cistern with calcification and ring-enhancement.Moreover,no Mycobacterium tuberculosis was found in cerebrospinal fluid by polymerase chain reaction(PCR).The lesion was initially diagnosed as a tumor,while postoperative pathology combined with PCR indicated tuberculoma.The patient continued postoperative anti-tuberculosis treatment.At present,the patient's condition is stable and the symptoms are partially relieved compared with those before surgery.CONCLUSION This case confirmed that isolated intracranial tuberculoma can occur in the suprasellar cistern.Therefore,for space-occupying lesions in the suprasellar cistern,tuberculoma should be included in the differential diagnosis even if there is no history or indication of tuberculosis infection. 展开更多
关键词 Tuberculosis Intracranial tuberculoma Suprasellar cistern Ocular motility disorder PTOSIS Case report
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Hormonal (Thyroxin, Cortisol) and Immunological (Leucocytes) Responses to Cistern Size and Heat Stress in Tunisia
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作者 Rim Ben Younes Moez Ayadi +3 位作者 Taha Najar Margherita Caccamo Iris Schadt Moncef Ben M'Rad 《Journal of Life Sciences》 2011年第5期332-338,共7页
This study was designed to determine the effects of heat stress on plasma leucocytes, Thyroxin (T4) and cortisol concentrations in dairy cows with small and large cistern under hot climate. This experiment was carri... This study was designed to determine the effects of heat stress on plasma leucocytes, Thyroxin (T4) and cortisol concentrations in dairy cows with small and large cistern under hot climate. This experiment was carried out in 2006, in North Tunisia, using a randomized block design per udder cistern size, using 60 Holstein cows. Cows were classified according to udder cistern size by ultrasonography as large-cisterned (44 ±13 cm2; LC) and small-cisterned (21 ± 8 cm2; SC). The experiment was carried out in two different periods: spring (Apr. 5 (D1)) and summer (July 19 (D2), Aug. 19 (D3) and Sept. 19 (D4)). On each test day, temperature and relative humidity data were registered hourly and cows' blood was sampled from the jugular vein to determine serum concentrates of cortisol and T4. Leucocytes (lyrnphocytes, eosinophils, neutrophils and monocytes) were counted differentially, and percentages of lymphocytes relative to total counted cells were calculated. Mean temperature-humidity index (THI) values were 62 ±2, 79 ±2, 84 ±2, and 77 ±1 in DI, D2, D3, and D4, respectively. Lymphocyte incidence relative to total cell counts and T4 concentrations were affected by test day (P 〈 0.001). Lymphocytes (%) were significantly less in hotter months. During summer, T4 concentration at D2 (87.4 nmol/L) was higher relative to concentrations at D3 (42.8 nmol/L) and D4 (53.5 nmol/L). T4 concentrations were higher (P 〈 0.01) in SC cows (67.7 ±0.1 nmol/L) compared to LC cows (52.7 ±0.1 nmol/L). Cortisol concentration was effected neither by test day nor by cistern size. However, the decrease of lymphocyte concentration during summer compared to spring could be considered as an evidence of the suppression of cows' immune system under heat stress. 展开更多
关键词 Heat stress cistern size CORTISOL THYROXIN lymphocytes.
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The Development and Application of CISMOD 1.0, a New Computerized Tool for Designing Wildlife Rainwater Cisterns
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作者 Ariel Ortega Dave Menicucci 《Computational Water, Energy, and Environmental Engineering》 2021年第2期71-81,共11页
This article reports on a case study of the research and development of a new tool to assist in the design of rainwater cisterns. A rainwater cistern is a way to improve wildlife habitat because it can be situated in ... This article reports on a case study of the research and development of a new tool to assist in the design of rainwater cisterns. A rainwater cistern is a way to improve wildlife habitat because it can be situated in locations that do not have natural water sources, such as streams or wells that can supply water for storage. However, the design and sizing of such a system can be challenging because a number of constantly varying factors must be considered, such as changing precipitation patterns, the evaporative losses from the cistern and </span><span style="font-family:Verdana;">animal water consumption. No standardized sizing methodology currently</span><span style="font-family:Verdana;"> exists for designing wildlife rainwater cisterns. In this article we present a new method for assisting in optimally sizing a rainwater cistern. We discuss how we implemented the quantitative portion of this methodology into a new Excel? model called CISMOD, which we configured for general use by wildlife professionals. We describe the methodology for designing a rainwater cistern based on standard engineering techniques. We then present and discuss our experience in applying the model to design two rainwater cisterns in an area of the Jemez Mountains in northern New Mexico, USA. The CISMOD model and a user manual are available at no cost for wildlife professionals. 展开更多
关键词 cistern WILDLIFE Design SIZING Construction
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Microsurgical anatomy of the ambient cistern and its related arachnoidal membranes
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作者 樊俊 《外科研究与新技术》 2011年第3期228-228,共1页
Objective To study microanatomy features and clinical significance of ambient cisterns and their arachnoidal membranes in detail. Methods Ambient cisterns including their shapes,borders,contents and arachnoidal membra... Objective To study microanatomy features and clinical significance of ambient cisterns and their arachnoidal membranes in detail. Methods Ambient cisterns including their shapes,borders,contents and arachnoidal membranes were observed in 20 cadaveric brains using an operating microscope. Results The 展开更多
关键词 Microsurgical anatomy of the ambient cistern and its related arachnoidal membranes
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CAN GREENWALLS CONTRIBUTE TO STORMWATER MANAGEMENT?A STUDY OF CISTERN STORAGE GREENWALL FIRST FLUSH CAPTURE
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作者 Barry Kew Eliza Pennypacker Stuart Echols 《Journal of Green Building》 2014年第3期85-99,共15页
The authors set out to study the stormwater management viability of greenwalls in a simulated retention of roof runoff,using a cistern for simulated runoff to irrigate the greenwalls.By experimenting with two greenwal... The authors set out to study the stormwater management viability of greenwalls in a simulated retention of roof runoff,using a cistern for simulated runoff to irrigate the greenwalls.By experimenting with two greenwalls of different exposures(one southeast and one northwest),this study demonstrated that the southeast facing greenwall and the northwest facing greenwall retained comparably favorable amounts to greenroof stormwater retention systems.With more and more competition for limited horizontal surface area in urbanized and urbanizing areas,the use of vertical surfaces for stormwater mitigation and evapotranspiration has attractive potential.This article presents the background,project,methods,findings,and conclusions of the study. 展开更多
关键词 greenwalls stormwater runoff cistern retention
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大脑前纵裂池表皮样囊肿1例并文献复习
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作者 林和璞 马晓东 +2 位作者 徐如祥 张鹏飞 陈鹤文 《国际神经病学神经外科学杂志》 2024年第1期48-50,共3页
报告1例生长于颅内罕见部位的表皮样囊肿病例并复习相关文献。该表皮样囊肿位于大脑前纵裂池,通过术前评估,经前纵裂入路,囊内容物完全切除,囊壁次全切除,无新发症状。对位于颅内罕见部位的表皮样囊肿存在术前诊断困难的问题,手术方案... 报告1例生长于颅内罕见部位的表皮样囊肿病例并复习相关文献。该表皮样囊肿位于大脑前纵裂池,通过术前评估,经前纵裂入路,囊内容物完全切除,囊壁次全切除,无新发症状。对位于颅内罕见部位的表皮样囊肿存在术前诊断困难的问题,手术方案需根据不同部位采取不同入路,术后并发症的发生与常见部位的颅内表皮样囊肿并无明显区别。 展开更多
关键词 前纵裂池 表皮样囊肿 文献复习
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脑室-腰大池序贯引流治疗重度脑室出血后继发引流依赖性脑积水的原因分析
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作者 张晋宁 《中华神经外科疾病研究杂志》 CAS 2024年第5期35-38,共4页
目的探究对重度脑室出血患者行脑室-腰大池序贯引流后发生脑积水的影响因素。方法选择2017年1月至2022年1月泉州市第一医院神经外科收治的重度脑室出血患者99例。根据是否继发脑积水分为实验组(n=33)和对照组(n=66),比较分析两组患者的... 目的探究对重度脑室出血患者行脑室-腰大池序贯引流后发生脑积水的影响因素。方法选择2017年1月至2022年1月泉州市第一医院神经外科收治的重度脑室出血患者99例。根据是否继发脑积水分为实验组(n=33)和对照组(n=66),比较分析两组患者的临床数据。结果实验组患者Graeb评分更高,脑脊液引流速度≤8-10 ml/h的比例更高,引流时程≤7 d的比例更高,上述差异均具有统计学意义(P<0.05),实验组患者治疗有效率为72.73%,显著低于对照组(88.76%),差异有统计学意义(P<0.05)。结论脑室-腰大池序贯引流治疗重度脑室出血是安全有效的。高Graeb评分、脑脊液引流速度慢(≤8-10 ml/h)、引流时程短(≤7 d)等均是脑室出血引流术后继发引流依赖性脑积水的独立危险因素,针对性地减少上述危险因素,可减少脑积水的发生率,改善预后。 展开更多
关键词 脑室引流 腰大池引流 脑室出血 脑积水
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经脊柱椎间隙穿刺蛛网膜下腔脑桥前池置管药物输注技术应用指南
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作者 李欣宁 王亚平 +9 位作者 邹定全 张伟 李欣 贺佩瑶 周浩宬 杨彤飚 朱钧 洪波 张宇 肖艳英 《中南大学学报(医学版)》 CAS CSCD 北大核心 2024年第1期1-10,共10页
目的:鞘内镇痛药物的分布特点和目前置管技术的限制使传统的鞘内镇痛方法对头面部难治性疼痛无法发挥作用。本技术应用指南的制订旨在促进经脊柱椎间隙穿刺蛛网膜下腔脑桥前池置管药物输注技术的推广和规范、安全应用。方法:工作小组采... 目的:鞘内镇痛药物的分布特点和目前置管技术的限制使传统的鞘内镇痛方法对头面部难治性疼痛无法发挥作用。本技术应用指南的制订旨在促进经脊柱椎间隙穿刺蛛网膜下腔脑桥前池置管药物输注技术的推广和规范、安全应用。方法:工作小组采用改良德尔菲法,邀请本技术领域的10名专家对脑桥前池药物输注技术的相关议题进行3轮电子邮件函询及3轮现场会议讨论。结果:针对脑桥前池药物输注技术的有效性和安全性,在技术原理、适应证和禁忌证、患者准备、脑桥前池置管手术规范、镇痛药物选择和剂量衔接、术后镇痛管理和并发症防治共7个议题形成一致意见(同意率≥80%)。结论:脑桥前池药物输注镇痛技术应用于头面部难治性疼痛患者具有微创、安全、有效的优点,既可减轻长期罹受疼痛患者的痛苦,也能帮助一些患者保持人生最后一程的生活质量和生命尊严,值得在国内外相关专业领域推广和规范应用。 展开更多
关键词 鞘内药物输注 脑桥前池 癌性疼痛 神经病理性疼痛 难治性疼痛 头面部疼痛 改良德尔菲法
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通过自制套管给予小脑延髓池脂多糖诱发大鼠中枢神经系统感染
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作者 郭瑶 郭畅 +5 位作者 王凯妮 臧若琪 高洁 马洋 陈怡彤 张宇 《神经解剖学杂志》 CAS CSCD 北大核心 2024年第3期334-340,共7页
目的:本研究旨在应用自制给药套管植入大鼠小脑延髓池(CMC),以实现给清醒大鼠多次给药。方法:自制给药套管,从大鼠颅骨枕外嵴中点开孔,沿枕骨内壁下行直至套管尖端达CMC,然后颅钉和自凝树脂固定。应用脂多糖(LPS)作为局部炎性刺激物注射... 目的:本研究旨在应用自制给药套管植入大鼠小脑延髓池(CMC),以实现给清醒大鼠多次给药。方法:自制给药套管,从大鼠颅骨枕外嵴中点开孔,沿枕骨内壁下行直至套管尖端达CMC,然后颅钉和自凝树脂固定。应用脂多糖(LPS)作为局部炎性刺激物注射到CMC诱发神经炎症,并使用X线、行为学检测及免疫荧光染色评估该方法的可行性。结果:X线及滂胺天蓝染料确认脑内置管埋置位置合适。经给药管注射LPS组大鼠较Control组大鼠面部机械痛阈值降低(P<0.001);LPS组大鼠在旷场中央停留时间较Control组大鼠显著下降(P<0.01)。免疫荧光染色结果表明LPS激活三叉神经脊束核尾侧亚核(SpVc)小胶质细胞。结论:该方法可有效作用于大鼠SpVc,适用于清醒大鼠小脑延髓池内的重复多次给药。 展开更多
关键词 三叉神经脊束核尾侧亚核 小脑延髓池 口面部疼痛 置管给药 神经炎症 大鼠
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腰大池引流联合生物蛋白胶黏贴肌瓣治疗骶管囊肿的疗效分析
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作者 王纪华 谢佳芯 +3 位作者 刘羽阳 姜海莉 杨凌 封亚平 《中华神经外科疾病研究杂志》 CAS 2024年第2期19-24,共6页
目的探讨腰大池引流联合生物蛋白胶黏贴肌瓣治疗骶管囊肿的疗效分析.方法回顾性分析2018年1月至2023年6月收治的82例症状性骶管囊肿患者的资料,均行腰大池引流联合生物蛋白胶黏贴肌瓣治疗骶管囊肿.结果所有患者均顺利完成手术并完成随访... 目的探讨腰大池引流联合生物蛋白胶黏贴肌瓣治疗骶管囊肿的疗效分析.方法回顾性分析2018年1月至2023年6月收治的82例症状性骶管囊肿患者的资料,均行腰大池引流联合生物蛋白胶黏贴肌瓣治疗骶管囊肿.结果所有患者均顺利完成手术并完成随访,随访时间6-14个月,平均10个月.采用日本骨科学会(JOA)和疼痛视觉模拟评分(VAS)评估患者术后3、6个月的神经功能改善情况,JOA评分术前(16.09±1.91)分,术后升至(23.09±1.77)分,差异具有统计学意义(t=-40.75,P<0.05).VAS评分术前(5.52±1.28)分,术后降至(2.22±0.83)分,差异有统计学意义(t=31.023,P<0.05).疼痛消失38例(46.34%),改善36例(43.90%),无变化5例(6.10%);感觉障碍消失19例(23.17%),改善26例(31.71%),无变化6例(7.32%);下肢无力消失2例(2.44%),改善5例(6.10%),无变化2例(2.44%);排便障碍消失6例(7.32%),改善15例(18.29%),无变化4例(4.88%);排尿障碍消失6例(7.32%),改善13例(15.85%),无变化4例(4.88%);性功能障碍消失0例(0.00%),改善2例(2.44%),无变化3例(3.66%).结论腰大池引流联合生物蛋白胶黏贴肌瓣是治疗骶管囊肿有效、复发率低、并发症少的治疗方式. 展开更多
关键词 骶管囊肿 生物蛋白胶 肌瓣 腰大池引流 疗效
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结核性脑积水患者的侧脑室和腰大池脑脊液参数相关性分析
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作者 孙久君 殷成 《实用医院临床杂志》 2024年第1期148-151,共4页
目的探讨在脑室腹腔分流术治疗结核性脑积水时,使用侧脑室脑脊液和使用腰大池脑脊液化验结果作为分流参考指标的差异。方法回顾性纳入28例结核性脑积水患者。在进行脑室腹腔分流术之前,分别从腰大池和侧脑室取脑脊液,送常规与生化检测... 目的探讨在脑室腹腔分流术治疗结核性脑积水时,使用侧脑室脑脊液和使用腰大池脑脊液化验结果作为分流参考指标的差异。方法回顾性纳入28例结核性脑积水患者。在进行脑室腹腔分流术之前,分别从腰大池和侧脑室取脑脊液,送常规与生化检测。对上述来源两个不同部位的脑脊液进行参数分析,并随访患者手术疗效。结果腰大池有核细胞、葡萄糖、氯化物、蛋白质含量与侧脑室这些指标有明显相关性(P<0.05);腰大池脑脊液有核细胞和蛋白水平明显高于侧脑室(P<0.05)。后期随访过程中,除1例失去联系,其余患者手术效果良好。结论由于侧脑室脑脊液与腰大池脑脊液存在明显差异,脑室腹腔分流术应取侧脑室脑脊液作为分流的临床参考指标。 展开更多
关键词 结核性脑积水 脑脊液 腰大池 侧脑室 脑室腹腔分流术
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The prospective study of the relationship between perimesencephalic cistern of CT scanning and the outcome of the patients with acute craniocerebral injury 被引量:2
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作者 龙连圣 江基尧 《Chinese Journal of Traumatology》 CAS 2003年第4期226-228,共3页
Objective: To explore prospectively the relationship between the state of perimesencephalic cistern and the degree of deformation of the midbrain on CT scanning and the outcome of the patients with acute craniocerebra... Objective: To explore prospectively the relationship between the state of perimesencephalic cistern and the degree of deformation of the midbrain on CT scanning and the outcome of the patients with acute craniocerebral injury.Methods: The CT scan features including the states of perimesencephalic cisterns, the deformations of the midbrain and the ratios of the occipitofrontal diameter and the transverse diameter of the midbrain of 132 cases were measured. The GOS of the patients 3 months after trauma were regarded as outcome.Results: The rate of unfavorable outcome ( dead, vegetative status, severe disability ) was significantly correlated with perimesencephalic cistern narrower than 1mm (P < 0.05), especially narrower than 0.5 mm (P < 0.005), deformed midbrain (P< 0.005) or abnormal ratio ( < 0.9 or >.1) of the occipitofrontal diameter and transverse diameter of the midbrain (P < 0.01). But the patient's perimesencephalic cistern wider than 1mm and the patients without deformed midbrain got favorable outcome (moderate disability/good recovery).Conclusions: The state of the compressedperimesencephalic cistern ( < 1 mm) and the deformation of the midbrain may significantly indicate unfavorable outcome of the patients with acute craniocerebral injury. 展开更多
关键词 Perimesencephalic cistern CT scanning OUTCOME Acute craniocerebral injury
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持续腰大池引流术与脑脊液置换术治疗自发性蛛网膜下腔出血患者的效果比较
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作者 周玉霞 王彦平 《中国民康医学》 2024年第5期142-145,共4页
目的:比较持续腰大池引流术与脑脊液置换术治疗自发性蛛网膜下腔出血患者的效果。方法:选取2022年1月至2023年10月该院收治的60例自发性蛛网膜下腔出血患者进行前瞻性研究,按照随机数字表法将其分为研究组和对照组各30例。对照组采用脑... 目的:比较持续腰大池引流术与脑脊液置换术治疗自发性蛛网膜下腔出血患者的效果。方法:选取2022年1月至2023年10月该院收治的60例自发性蛛网膜下腔出血患者进行前瞻性研究,按照随机数字表法将其分为研究组和对照组各30例。对照组采用脑脊液置换术治疗,研究组采用持续腰大池引流术治疗,比较两组临床相关指标水平、手术前后颅内压、预后良好率、术后1个月内并发症发生率和术后神经功能指标[血清神经轴突导向因子-1(netrin-1)、基质金属蛋白酶-9(MMP-9)]水平。结果:研究组血肿清除率高于对照组,头痛消失时间、颅内压恢复正常时间和脑脊液转清时间均短于对照组,差异有统计学意义(P<0.05);术后5、7 d,研究组颅内压均低于对照组,差异有统计学意义(P<0.05);研究组预后良好率为93.33%(28/30),高于对照组的73.33%(22/30),差异有统计学意义(P<0.05);研究组术后并发症发生率为3.33%(1/30),低于对照组的26.67%(8/30),差异有统计学意义(P<0.05);术后1个月,两组MMP-9水平均低于术后5 d,且研究组低于对照组,两组netrin-1水平均高于术后5 d,且研究组高于对照组,差异有统计学意义(P<0.05)。结论:持续腰大池引流术治疗自发性蛛网膜下腔出血患者可提高预后良好率,改善临床相关指标和神经功能指标水平,降低颅内压和并发症发生率,效果优于脑脊液置换术治疗。 展开更多
关键词 脑脊液置换术 持续腰大池引流术 自发性蛛网膜下腔出血 神经功能 颅内压 并发症
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慢性硬膜下血肿术后张力性硬膜下积液3例并文献复习
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作者 胡玉鲲 张绪明 +2 位作者 蔡家晨 金科 孙成法 《中国微侵袭神经外科杂志》 CAS 2024年第5期284-289,共6页
目的探讨慢性硬膜下血肿(chronic subdural hematom,CSDH)术后并发张力性硬膜下积液(traumatic subdural effusion,TSE)治疗对策。方法回顾性分析3例CSDH术后并发张力性TSE病例资料,包括一般信息、临床表现、影像学结果、治疗及预后。... 目的探讨慢性硬膜下血肿(chronic subdural hematom,CSDH)术后并发张力性硬膜下积液(traumatic subdural effusion,TSE)治疗对策。方法回顾性分析3例CSDH术后并发张力性TSE病例资料,包括一般信息、临床表现、影像学结果、治疗及预后。中文数据库(中国知网、维普、万方等)中检索2024年4月前CSDH术后并发张力性TSE的相关研究。结果3例CSDH患者术后均有头痛、意识下降,部分有恶心、呕吐等颅高压表现。经影像学检查证实发生张力性TSE,并可见中线不同程度偏移,切口愈合不良,拆线后切口可见高压液体喷出。均经历2次以上手术引流仍无法治愈,最终采用腰大池持续引流,逐步治愈出院。检索中文文献,3例患者与本研究病例相似。结论张力性TSE是CSDH术后罕见并发症,应手术彻底开放血肿腔进行引流。如疗效不佳,术后行腰大池持续引流可有效改善预后。 展开更多
关键词 血肿 硬膜下 慢性 硬膜下积液 张力性 腰大池引流
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改良大骨瓣减压术联合持续腰大池引流治疗重型颅脑损伤伴蛛网膜下腔出血患者的效果
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作者 曹龙庆 吴彦涛 《中外医学研究》 2024年第15期56-60,共5页
目的:观察改良大骨瓣减压术联合持续腰大池引流治疗重型颅脑损伤伴蛛网膜下腔出血患者的效果。方法:选取2020年8月—2023年5月西安市高陵区医院神经外科收治的60例重型颅脑损伤伴蛛网膜下腔出血患者作为研究对象,按照随机数表法将患者... 目的:观察改良大骨瓣减压术联合持续腰大池引流治疗重型颅脑损伤伴蛛网膜下腔出血患者的效果。方法:选取2020年8月—2023年5月西安市高陵区医院神经外科收治的60例重型颅脑损伤伴蛛网膜下腔出血患者作为研究对象,按照随机数表法将患者分为研究组和对照组,各30例。两组均采用改良大骨瓣减压术治疗,在此基础上,对照组采用常规腰椎穿刺引流,研究组采用持续腰大池引流,比较两组临床症状改善情况、术后3个月预后情况、术后1个月内并发症发生情况及术后5 d、1个月神经功能。结果:研究组血肿清除率、术后3个月预后良好率高于对照组,脑脊液转清时间短于对照组,术后1个月内并发症发生率低于对照组,差异有统计学意义(P<0.05);术后7 d,两组颅内压较术后5 d降低,且研究组低于对照组,差异有统计学意义(P<0.05);术后1个月,两组netrin-1水平升高,改良Rankin量表(modified Rankin scale,MRS)评分降低,且研究组netrin-1水平高于对照组,MRS评分低于对照组,差异有统计学意义(P<0.05)。结论:改良大骨瓣减压术联合持续腰大池引流能促进重型颅脑损伤伴蛛网膜下腔出血患者血肿清除,降低颅内压和术后并发症发生风险,改善神经功能和预后表现。 展开更多
关键词 改良大骨瓣减压术 持续腰大池引流 重型颅脑损伤 蛛网膜下腔出血 预后表现
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腰大池持续引流联合尼莫地平治疗动脉瘤性蛛网膜下腔出血术后脑血管痉挛的效果及对炎性因子的影响
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作者 王乃冰 袁兴 李俊明 《临床医学研究与实践》 2024年第32期67-70,共4页
目的探究腰大池持续引流联合尼莫地平治疗动脉瘤性蛛网膜下腔出血(aSAH)术后脑血管痉挛的效果及对炎性因子的影响。方法选择2021年5月至2022年8月收治的80例aSAH术后脑血管痉挛患者作为研究对象,以随机数字表法将其分为对照组、观察组,... 目的探究腰大池持续引流联合尼莫地平治疗动脉瘤性蛛网膜下腔出血(aSAH)术后脑血管痉挛的效果及对炎性因子的影响。方法选择2021年5月至2022年8月收治的80例aSAH术后脑血管痉挛患者作为研究对象,以随机数字表法将其分为对照组、观察组,每组40例。对照组接受腰椎穿刺联合尼莫地平治疗,观察组给予腰大池持续引流联合尼莫地平治疗。比较两组的治疗效果。结果治疗后,观察组的大脑中动脉平均血流速度(MCA-Vm)、大脑前动脉平均血流速度(ACA-Vm)以及大脑后动脉平均血流速度(PCA-Vm)大于对照组(P<0.05)。治疗后,观察组的肿瘤坏死因子-α(TNF-α)、白细胞介素-8(IL-8)以及C-反应蛋白(CRP)水平低于对照组(P<0.05)。治疗后,观察组的格拉斯哥昏迷量表(GCS)评分高于对照组,美国国立卫生研究院卒中量表(NIHSS)评分低于对照组(P<0.05)。结论腰大池持续引流联合尼莫地平治疗aSAH术后脑血管痉挛的效果显著,可调节患者的炎性因子水平,改善脑血流状态及昏迷情况,促进脑部神经功能恢复,值得推广。 展开更多
关键词 腰大池持续引流 尼莫地平 动脉瘤性蛛网膜下腔出血 脑血管痉挛 炎性因子
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持续腰大池引流术治疗动脉瘤破裂后引起蛛网膜下腔出血的临床疗效分析
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作者 常健 廖昆 龚明 《系统医学》 2024年第17期120-123,共4页
目的分析持续腰大池引流术用于动脉瘤破裂后引起蛛网膜下腔出血中的治疗效果。方法非随机选取2020年1月—2023年6月兴义市人民医院神经外科收治的100例动脉瘤破裂后引起蛛网膜下腔出血的患者为研究对象。按治疗方式不同分为两组,每组50... 目的分析持续腰大池引流术用于动脉瘤破裂后引起蛛网膜下腔出血中的治疗效果。方法非随机选取2020年1月—2023年6月兴义市人民医院神经外科收治的100例动脉瘤破裂后引起蛛网膜下腔出血的患者为研究对象。按治疗方式不同分为两组,每组50例。对照组行常规腰椎穿刺引流术,研究组行持续腰大池引流术治疗。比较两组治疗效果、脑血管痉挛、颅内感染情况、格拉斯哥昏迷评分(Glasgow Coma Scale,GCS)、改良Rankin量表评分。结果研究组总有效率为96.00%(48/50),高于对照组的80.00%(40/50),差异有统计学意义(χ^(2)=4.640,P<0.05)。研究组术后脑血管痉挛、颅内感染发生率低于对照组,差异有统计学意义(P均<0.05)。术后,研究组GCS评分高于对照组,改良Rankin量表评分低于对照组,差异有统计学意义(P均<0.05)。结论持续腰大池引流术治疗方案可以提升整体治疗效果,减少颅内感染及脑血管痉挛情况,缓解患者病情。 展开更多
关键词 持续腰大池引流术 动脉瘤破裂 蛛网膜下腔出血 临床疗效
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