The cleavage reactions of Ser-His and its N-terminal phosphorylated form - N-(O,O-diisopropyl) phosphoryl seryl-histidine (DIPP-Ser-His) were studied on DNA. It was found that the phosphorylation of Ser-His caused the...The cleavage reactions of Ser-His and its N-terminal phosphorylated form - N-(O,O-diisopropyl) phosphoryl seryl-histidine (DIPP-Ser-His) were studied on DNA. It was found that the phosphorylation of Ser-His caused the lost of the cleavage activity on DNA. The result might give some clue on the regulation of the activity of protein by phosphorylation.展开更多
文摘The cleavage reactions of Ser-His and its N-terminal phosphorylated form - N-(O,O-diisopropyl) phosphoryl seryl-histidine (DIPP-Ser-His) were studied on DNA. It was found that the phosphorylation of Ser-His caused the lost of the cleavage activity on DNA. The result might give some clue on the regulation of the activity of protein by phosphorylation.