Implementing clinical trials with large multicenter samples is an important way to scientifically evaluate and demonstrate the curative effect of moxibustion.At present,clinical trials on moxibustion with large multic...Implementing clinical trials with large multicenter samples is an important way to scientifically evaluate and demonstrate the curative effect of moxibustion.At present,clinical trials on moxibustion with large multicenter samples are prospering in China.It is necessary for research units to have good research professionals and technical platforms as well as a highly standardized and scientifically feasible methodology of research.Taking tasks in the ongoing national 973 project and in the sci-tech support program of the "11th 5-year plan",for example,this research captures the characteristics of moxibustion,carries out deep analysis and introduces specific methods and the important significance of clinical research tasks on moxibustion in designing multicenter plans,implementing experiments,supervising quality and strengthening compliance.展开更多
Two randomized controlled trials of acupuncture concerning polycystic ovary syndrome（PCOS） and stress urinary incontinence（SUI） were published simultaneously in the 24 th issue, 2017 of The Journal of the American...Two randomized controlled trials of acupuncture concerning polycystic ovary syndrome（PCOS） and stress urinary incontinence（SUI） were published simultaneously in the 24 th issue, 2017 of The Journal of the American Medical Association（JAMA）. A trial involving PCOS indicated that active acupuncture did not increase live birth compared with sham acupuncture; meanwhile, another trial referring to SUI showed that electroacupuncture resulted in less urine leakage compared with sham electroacupuncture. With an eye to the negative and positive results of acupuncture, three pivotal factors should be contemplated：（1） proper illness for acupuncture, that is, a problem need to be solved in current medical science, and acupuncture may really work for it;（2） proper pre-studied primary outcome, which is better be objective and repeatedly measurable to reveal the therapeutic effect of acupuncture truly and objectively;（3） proper sham control, which can blind the patients to the upmost extent with minimal biological effects. Through the publication of clinical trials of acupuncture in high-impact journals in recent years, researchers should have confidence in their clinical trials by pondering over these three pivotal factors.展开更多
基金Supported by the National "11th 5-year Plan" (2006BAI12B04-2)National Plan on Developing Key Basic Researches(973 Plan)(2009CB522902)+1 种基金State Natural Science Fund(30760320)a project of Key Sci-tech Support Plan in Jiangxi
文摘Implementing clinical trials with large multicenter samples is an important way to scientifically evaluate and demonstrate the curative effect of moxibustion.At present,clinical trials on moxibustion with large multicenter samples are prospering in China.It is necessary for research units to have good research professionals and technical platforms as well as a highly standardized and scientifically feasible methodology of research.Taking tasks in the ongoing national 973 project and in the sci-tech support program of the "11th 5-year plan",for example,this research captures the characteristics of moxibustion,carries out deep analysis and introduces specific methods and the important significance of clinical research tasks on moxibustion in designing multicenter plans,implementing experiments,supervising quality and strengthening compliance.
文摘Two randomized controlled trials of acupuncture concerning polycystic ovary syndrome（PCOS） and stress urinary incontinence（SUI） were published simultaneously in the 24 th issue, 2017 of The Journal of the American Medical Association（JAMA）. A trial involving PCOS indicated that active acupuncture did not increase live birth compared with sham acupuncture; meanwhile, another trial referring to SUI showed that electroacupuncture resulted in less urine leakage compared with sham electroacupuncture. With an eye to the negative and positive results of acupuncture, three pivotal factors should be contemplated：（1） proper illness for acupuncture, that is, a problem need to be solved in current medical science, and acupuncture may really work for it;（2） proper pre-studied primary outcome, which is better be objective and repeatedly measurable to reveal the therapeutic effect of acupuncture truly and objectively;（3） proper sham control, which can blind the patients to the upmost extent with minimal biological effects. Through the publication of clinical trials of acupuncture in high-impact journals in recent years, researchers should have confidence in their clinical trials by pondering over these three pivotal factors.
