Objective: To investigate the characteristics of proximal bronchial invasion of lung cancer for different types. Methods: Proximal bronchus of 151 operatively resected specimens of hilar type lung cancer were selected...Objective: To investigate the characteristics of proximal bronchial invasion of lung cancer for different types. Methods: Proximal bronchus of 151 operatively resected specimens of hilar type lung cancer were selected for cross-sectional pathological study. Forty-one specimens were obtained from total pulmonectomy, and 110 from pulmonary lobectomy. Results: Evidence showed that the direct invasion of tumor cells through the submucosal layer or multiple layers was the major form of lung cancer spread; 96.6% of the cancerous invasion occurred at the proximal bronchial wall less than 1.5 cm apart from the margin of the cancer. The extension of invasion was correlated with the histopathologic type of cancer, mode of invasion and TNM classification (pT, pN). Besides, the invasion in the bronchial wall by metastatic lymph nodes was also an important way for the cancer to spread. Conclusion: In order to achieve the radical removal of a tumor, it is imperative to keep a distance of 1.5 cm or more between the excision margin of the bronchus and the tumor, and to completely resect the hilar and mediastinal lymph nodes.展开更多
The incidence of gastric cancer (GC) in young patients has showed a stable or even slightly increasing trend in recent years all over the world. Little is known about the clinicpathological features of young patients ...The incidence of gastric cancer (GC) in young patients has showed a stable or even slightly increasing trend in recent years all over the world. Little is known about the clinicpathological features of young patients with GC in Ningxia region, located in the northwest part of China. To define the clinicpathological features of GC in young patients in this region, 117 patients with GC, who were admitted to the Department of Medical Oncology, General Hospital of Ningxia Medical University, Ningxia, China, were enrolled in a retrospective database between 2000 and 2005. The data from 55 patients aged less than 35 years old were compared with those from 62 controls aged between 36 and 70. It was found that in young group, the percentages of females, the tumors in the lower third of the stomach, tumor size larger than 4 cm, macroscopic type Borrmann III tumors, poorly differentiated histology, the 7th?T stage T3 + T4, the distribution of tumor-nodes-metastasis(TNM)stage IV, surgical exploratory laparoscopy, and anemia symptoms were significantly higher than those in the control group (P?< 0.05). The 5-year survival in the young group was lower than that in the control group (21.8%?vs.?48.4%,?P?< 0.05). It was obvious that the clinicpathological features of GC in young patients were different from those in the control group. Focusing on early diagnostic rate and choosing a suitable operative treatment should be critical to improve prognosis of young patients with GC in Ningxia region of China.展开更多
文摘Objective: To investigate the characteristics of proximal bronchial invasion of lung cancer for different types. Methods: Proximal bronchus of 151 operatively resected specimens of hilar type lung cancer were selected for cross-sectional pathological study. Forty-one specimens were obtained from total pulmonectomy, and 110 from pulmonary lobectomy. Results: Evidence showed that the direct invasion of tumor cells through the submucosal layer or multiple layers was the major form of lung cancer spread; 96.6% of the cancerous invasion occurred at the proximal bronchial wall less than 1.5 cm apart from the margin of the cancer. The extension of invasion was correlated with the histopathologic type of cancer, mode of invasion and TNM classification (pT, pN). Besides, the invasion in the bronchial wall by metastatic lymph nodes was also an important way for the cancer to spread. Conclusion: In order to achieve the radical removal of a tumor, it is imperative to keep a distance of 1.5 cm or more between the excision margin of the bronchus and the tumor, and to completely resect the hilar and mediastinal lymph nodes.
文摘The incidence of gastric cancer (GC) in young patients has showed a stable or even slightly increasing trend in recent years all over the world. Little is known about the clinicpathological features of young patients with GC in Ningxia region, located in the northwest part of China. To define the clinicpathological features of GC in young patients in this region, 117 patients with GC, who were admitted to the Department of Medical Oncology, General Hospital of Ningxia Medical University, Ningxia, China, were enrolled in a retrospective database between 2000 and 2005. The data from 55 patients aged less than 35 years old were compared with those from 62 controls aged between 36 and 70. It was found that in young group, the percentages of females, the tumors in the lower third of the stomach, tumor size larger than 4 cm, macroscopic type Borrmann III tumors, poorly differentiated histology, the 7th?T stage T3 + T4, the distribution of tumor-nodes-metastasis(TNM)stage IV, surgical exploratory laparoscopy, and anemia symptoms were significantly higher than those in the control group (P?< 0.05). The 5-year survival in the young group was lower than that in the control group (21.8%?vs.?48.4%,?P?< 0.05). It was obvious that the clinicpathological features of GC in young patients were different from those in the control group. Focusing on early diagnostic rate and choosing a suitable operative treatment should be critical to improve prognosis of young patients with GC in Ningxia region of China.
