Type 2 diabetes mellitus(T2DM)is a metabolic disease caused by a glycolipid metabolism disorder and isletβ-cell dysfunction.SCP-80-I is a biologically active water-soluble polysaccharide isolated from sweet corncob,a...Type 2 diabetes mellitus(T2DM)is a metabolic disease caused by a glycolipid metabolism disorder and isletβ-cell dysfunction.SCP-80-I is a biologically active water-soluble polysaccharide isolated from sweet corncob,an agricultural byproduct.The hypoglycemic effects of SCP-80-I on T2DM mice and its mechanisms were investigated in this study.SCP-80-I was found to significantly reduce blood glucose and lipid deposition levels in T2DM mice,as well as decrease serum leptin and increase adiponectin secretion.Interestingly,real time-polymerase chain reaction(RT-PCR)and Western blotting results revealed that SCP-80-I could regulate the expression of several glycolipid metabolisms and insulin secretion genes and proteins,including 5'-AMP-activated protein kinase(AMPK),carnitine palmitoyltransferase I(CPTI),and acetyl coenzyme A carboxylase(ACC)in the liver and AMPK,sirtuin1(Sirtl),peroxisome proliferator-activated receptorycoactivator-1(PGC-1α),and uncoupling protein 2(UCP2)in the pancreas.To have a hypoglycemic effect,SCP-80-1 regulated glycolipid metabolism and islet cell function in the liver by regulating the AMPK/AC C/CPT1 signaling pathway and the AMPK/Sirt1/PGC-1αand AMPK/Sirtl/UCP2 signaling pathways.These findings improve our understanding of polysaccharides derived from sweet corncob and the use of SCP-80-I in the production of hypoglycemic foods.展开更多
本文介绍了一种用于COB(Chip On Board)光器件产品研发的工装夹具设计方案。随着光通信技术的迅猛发展,光器件在数据中心和传输网等领域的应用日益广泛。光通信器件的发展趋势主要集中在提高传输速率、减小尺寸、降低单元比特成本等方...本文介绍了一种用于COB(Chip On Board)光器件产品研发的工装夹具设计方案。随着光通信技术的迅猛发展,光器件在数据中心和传输网等领域的应用日益广泛。光通信器件的发展趋势主要集中在提高传输速率、减小尺寸、降低单元比特成本等方面。目前,光通信器件的传输速率已经达到了100G,并且未来有望突破400G,甚至向800G迈进。为了满足不断增长的光通信市场需求,本文提出了一种创新的工装夹具设计方案。该工装夹具具有小巧灵活的特点,旨在解决COB光器件产品研发过程中的光耦合问题。光耦合是光器件研发中关键的环节,影响着器件的性能和可靠性。因此,设计一种有效的工装夹具对于实现多品种、小批量产品的研发应用至关重要。本文将详细描述这种工装夹具的工作原理和3D结构设计,强调其在COB光器件研发中的重要性。这一工装方案的特点不仅在于其小巧的体积,还在于其灵活性,能够适应不同类型的光器件研发需求。通过这一工装夹具的应用,研发人员可以更高效地进行光耦合实验,提高产品的研发速度和质量。展开更多
In most developing countries, particularly in the countries of sub-Saharan Africa, corn cobs are considered as waste polluting the environment during the harvest period of this cereal. In order to valorize this agricu...In most developing countries, particularly in the countries of sub-Saharan Africa, corn cobs are considered as waste polluting the environment during the harvest period of this cereal. In order to valorize this agricultural waste, high-performance, inexpensive and low-energy consumption magnetic bioadsorbents were prepared from corn cobs. The chemically activated raw corn cob was magnetized by coating the surface with magnetite nanoparticles. The prepared biosorbents were characterized by FT-IR, XRD, FE-SEM associated with EDX, HR-TEM, TG analysis, BET surface area analysis and XPS. The maximum specific surface area of 35.22 m<sup>2</sup>/g was reached. An attempt to use of these magnetic biosorbents for the removal of heavy metal like Cr(VI) from aqueous solution was envisaged.展开更多
针对LED高光效、低功耗的要求,在分析LED光学性能的基础上,采用了COB（chip on board）即板上芯片封装技术。研究了不同电流下和点亮不同时间后,分析其LED光通量、光效和色温。研究分析影响LED光学性能的因素并进行测试。结果表明,用两...针对LED高光效、低功耗的要求,在分析LED光学性能的基础上,采用了COB（chip on board）即板上芯片封装技术。研究了不同电流下和点亮不同时间后,分析其LED光通量、光效和色温。研究分析影响LED光学性能的因素并进行测试。结果表明,用两种色温接近3 000 K的样品,电流由500 m A增大到900 m A,色温升高了1.685%、2.626%,光通量也随着电流的变大而升高68.532%、84.625%,但相反光效却降低了13.535%、9.971%;而在电流保持不变的情况下,点亮的时间由0~1 min、0~5 min、0~10 min,其色温分别上升了0.537%、1.209%、2.384%;0.369%、1.104%、2.943%,同时,光通量分别降低1.474%、4.855%、7.493%;2.073%、3.859%、7.793%,光效也分别降低2.527%、4.617%、6.671%;2.171%、4.903%、7.579%。实验发现,电流与点亮时间直接影响LED光学性能。展开更多
基金financially supported by the Doctoral Scientific Research Start-up Foundation of the Harbin University of Commerce (2019DS098)the Young Innovation Talents Project from the Harbin University of Commerce (2019CX31)the Graduate Innovation Fund from the Harbin University of Commerce (YJSCX2019–615HSD)。
文摘Type 2 diabetes mellitus(T2DM)is a metabolic disease caused by a glycolipid metabolism disorder and isletβ-cell dysfunction.SCP-80-I is a biologically active water-soluble polysaccharide isolated from sweet corncob,an agricultural byproduct.The hypoglycemic effects of SCP-80-I on T2DM mice and its mechanisms were investigated in this study.SCP-80-I was found to significantly reduce blood glucose and lipid deposition levels in T2DM mice,as well as decrease serum leptin and increase adiponectin secretion.Interestingly,real time-polymerase chain reaction(RT-PCR)and Western blotting results revealed that SCP-80-I could regulate the expression of several glycolipid metabolisms and insulin secretion genes and proteins,including 5'-AMP-activated protein kinase(AMPK),carnitine palmitoyltransferase I(CPTI),and acetyl coenzyme A carboxylase(ACC)in the liver and AMPK,sirtuin1(Sirtl),peroxisome proliferator-activated receptorycoactivator-1(PGC-1α),and uncoupling protein 2(UCP2)in the pancreas.To have a hypoglycemic effect,SCP-80-1 regulated glycolipid metabolism and islet cell function in the liver by regulating the AMPK/AC C/CPT1 signaling pathway and the AMPK/Sirt1/PGC-1αand AMPK/Sirtl/UCP2 signaling pathways.These findings improve our understanding of polysaccharides derived from sweet corncob and the use of SCP-80-I in the production of hypoglycemic foods.
文摘本文介绍了一种用于COB(Chip On Board)光器件产品研发的工装夹具设计方案。随着光通信技术的迅猛发展,光器件在数据中心和传输网等领域的应用日益广泛。光通信器件的发展趋势主要集中在提高传输速率、减小尺寸、降低单元比特成本等方面。目前,光通信器件的传输速率已经达到了100G,并且未来有望突破400G,甚至向800G迈进。为了满足不断增长的光通信市场需求,本文提出了一种创新的工装夹具设计方案。该工装夹具具有小巧灵活的特点,旨在解决COB光器件产品研发过程中的光耦合问题。光耦合是光器件研发中关键的环节,影响着器件的性能和可靠性。因此,设计一种有效的工装夹具对于实现多品种、小批量产品的研发应用至关重要。本文将详细描述这种工装夹具的工作原理和3D结构设计,强调其在COB光器件研发中的重要性。这一工装方案的特点不仅在于其小巧的体积,还在于其灵活性,能够适应不同类型的光器件研发需求。通过这一工装夹具的应用,研发人员可以更高效地进行光耦合实验,提高产品的研发速度和质量。
文摘In most developing countries, particularly in the countries of sub-Saharan Africa, corn cobs are considered as waste polluting the environment during the harvest period of this cereal. In order to valorize this agricultural waste, high-performance, inexpensive and low-energy consumption magnetic bioadsorbents were prepared from corn cobs. The chemically activated raw corn cob was magnetized by coating the surface with magnetite nanoparticles. The prepared biosorbents were characterized by FT-IR, XRD, FE-SEM associated with EDX, HR-TEM, TG analysis, BET surface area analysis and XPS. The maximum specific surface area of 35.22 m<sup>2</sup>/g was reached. An attempt to use of these magnetic biosorbents for the removal of heavy metal like Cr(VI) from aqueous solution was envisaged.
文摘针对LED高光效、低功耗的要求,在分析LED光学性能的基础上,采用了COB（chip on board）即板上芯片封装技术。研究了不同电流下和点亮不同时间后,分析其LED光通量、光效和色温。研究分析影响LED光学性能的因素并进行测试。结果表明,用两种色温接近3 000 K的样品,电流由500 m A增大到900 m A,色温升高了1.685%、2.626%,光通量也随着电流的变大而升高68.532%、84.625%,但相反光效却降低了13.535%、9.971%;而在电流保持不变的情况下,点亮的时间由0~1 min、0~5 min、0~10 min,其色温分别上升了0.537%、1.209%、2.384%;0.369%、1.104%、2.943%,同时,光通量分别降低1.474%、4.855%、7.493%;2.073%、3.859%、7.793%,光效也分别降低2.527%、4.617%、6.671%;2.171%、4.903%、7.579%。实验发现,电流与点亮时间直接影响LED光学性能。
