The coarsening behavior of Cr precipitates in Cu-0.1Ag-0.5Cr alloy was investigated, and the effects of aging processes on the microstructure and properties were discussed. The results show that the radius for coheren...The coarsening behavior of Cr precipitates in Cu-0.1Ag-0.5Cr alloy was investigated, and the effects of aging processes on the microstructure and properties were discussed. The results show that the radius for coherent/semi-coherent transition of the Cr precipitates is determined from TEM micrographs as 1545nm. The calculated value of critical radius for a particle begining to lose coherency is about 12.5nm. The coherent (r<15nm) precipitates are found to coarsen and become semi-coherent during the passage of low-angle boundaries during recovery. The passage of high-angle boundaries through semi-coherent precipitates during recrystallization occurs by migration of the particle, resulting in the precipitates maintaining semi-coherent with the new grain.展开更多
Proper Orthogonal Decomposition (POD) provides a powerful modal transformation tool for stochastic dynamics. In this paper, coherency matrix-based proper orthogonal decomposition (CPOD) is presented as an innovati...Proper Orthogonal Decomposition (POD) provides a powerful modal transformation tool for stochastic dynamics. In this paper, coherency matrix-based proper orthogonal decomposition (CPOD) is presented as an innovative form of the POD based on cross power spectral density matrices. By introducing a discretizing scheme, the CPOD-based spectral representation method is obtained for use in stochastic simulation. Moreover, some criteria are proposed that allow the truncation order of CPOD to be conveniently determined. A numerical example to illustrate the application of the proposed method for the simulation of a wind velocity field is provided.展开更多
Many studies have focused on horizontal ground motion, resulting in many coherency functions for horizontal ground motion while neglecting related problems arising from vertical ground motion. However, seismic events ...Many studies have focused on horizontal ground motion, resulting in many coherency functions for horizontal ground motion while neglecting related problems arising from vertical ground motion. However, seismic events have demonstrated that the vertical components of ground motion sometimes govern the ultimate failure of structures. In this paper, a vertical coherency function model of spatial ground motion is proposed based on the Hao model and SMART 1 array records, and the validity of the model is demonstrated. The vertical coherency function model of spatial ground motion is also compared with the horizontal coherency function model, indicating that neither model exhibits isotropic characteristics. The value of the vertical coherency function has little correlation with that of the horizontal coherency function. However, the coherence of the vertical ground motion between a pair of stations decreases with their projection distance and the frequency of the ground motion. When the projection distance in the wave direction is greater than 800 meters, the coherency between the two points can be neglected.展开更多
Seismic coherence is used to detect discontinuities in underground media. However, strata with steeply dipping structures often produce false low coherence estimates and thus incorrect discontinuity characterization r...Seismic coherence is used to detect discontinuities in underground media. However, strata with steeply dipping structures often produce false low coherence estimates and thus incorrect discontinuity characterization results. It is important to eliminate or reduce the effect of dipping on coherence estimates. To solve this problem, time-domain dip scanning is typically used to improve estimation of coherence in areas with steeply dipping structures. However, the accuracy of the time-domain estimation of dip is limited by the sampling interval. In contrast, the spectrum amplitude is not affected by the time delays in adjacent seismic traces caused by dipping structures. We propose a coherency algorithm that uses the spectral amplitudes of seismic traces within a predefined analysis window to construct the covariance matrix. The coherency estimates with the proposed algorithm is defined as the ratio between the dominant the constructed covariance matrix. Thus, we eigenvalue and the sum of all eigenvalues of eliminate the effect of dipping structures on coherency estimates. In addition, because different frequency bands of spectral amplitudes are used to estimate coherency, the proposed algorithm has multiscale features. Low frequencies are effective for characterizing large-scale faults, whereas high frequencies are better in characterizing small-scale faults. Application to synthetic and real seismic data show that the proposed algorithm can eliminate the effect of dip and produce better coherence estimates than conventional coherency algorithms in areas with steeply dipping structures.展开更多
At present, the method to study spatial variation of ground motions is statistic analysis based on dense array re-cords such as SMART-1 array, etc. For lacking of information of ground motions, there is no coherency f...At present, the method to study spatial variation of ground motions is statistic analysis based on dense array re-cords such as SMART-1 array, etc. For lacking of information of ground motions, there is no coherency function model of base rock and different style site. Spatial variation of ground motions in elastic media is analyzed by deterministic method in this paper. Taking elastic half-space model with dislocation source of fault, near-field ground motions are simulated. This model takes strike-slip fault and earth media into account. A coherency func-tion is proposed for base rock site.展开更多
This paper analyzes cache coherency mechanism from the view of system. It firstly discusses caehe-memory hierarchy of Pentium Ⅲ SMP system, including memory area distribution, cache attributes control and bus transac...This paper analyzes cache coherency mechanism from the view of system. It firstly discusses caehe-memory hierarchy of Pentium Ⅲ SMP system, including memory area distribution, cache attributes control and bus transaction. Secondly it analyzes hardware snoopy mechanism of P6 bus and MESI state transitions adopted by Pentium Ⅲ. Based on these, it focuses on how muhiprocessors and the P6 bus cooperate to ensure cache coherency of the whole system, and gives the key of cache coherency design.展开更多
The procerebrum (PC) of the land slug Limax is the olfactory center involved in olfactory discrimination and learning. In the PC, an oscillation of local field potential (LFP) with 0.5 - 1 Hz is observed by electrophy...The procerebrum (PC) of the land slug Limax is the olfactory center involved in olfactory discrimination and learning. In the PC, an oscillation of local field potential (LFP) with 0.5 - 1 Hz is observed by electrophysiological extracellular recording. Additionally, spatiotemporal neural activities in the PC have been examined using optical recordings. However, extracellular recording is preferable to measure neural activities for a long time with a high speed, while it is not abundant in spatial information. In this study, we therefore attempted to elicit spatial information from extracellular recording. For this purpose, we evaluated spatial information included in the LFP compared with the spatiotemporal neural activities measured by the fluorescent voltage imaging. As a result, aversive odors induced the coherent spatiotemporal neural activities in the PC, and the increase in coherency was observed as a change in the LFP waveform. It was also evaluated as a decrease in entropy by analyzing the LFP oscillation patterns and wavelet analysis. Thus, although the LFP provides only one series of signals, the coherency of the spatiotemporal neural activities in the PC can be evaluated by applying extracellular recording with wavelet analysis.展开更多
The waveform data recorded during the site survey of the Naqu seismic array in Aug. 2004 were processed by the author. According to the relativity of site pairs in time and frequency domains, the reference values of t...The waveform data recorded during the site survey of the Naqu seismic array in Aug. 2004 were processed by the author. According to the relativity of site pairs in time and frequency domains, the reference values of the inner ring and outer ring were determined. The author evaluated the array deployed for site survey as the primary array, and the results show that the resolution of the primary array is high enough to locate earthquakes precisely.展开更多
While ptychography is an algorithm based on coherent illumination,satisfactory reconstructions can still be generated in most experiments,even though the radiation sources that are used are not ideally coherent.The un...While ptychography is an algorithm based on coherent illumination,satisfactory reconstructions can still be generated in most experiments,even though the radiation sources that are used are not ideally coherent.The underlying physics of this phenomenon is that the diffraction patterns of partially coherent illumination can be treated as those of purely coherent illumination by altering the intensities of the diffracted beams relative to their real values.On the other hand,due to the inconsistency in the altering interference among all the diffraction beams,noise/distortion is always involved in the reconstructed images.Furthermore,for a weak object,the noise/distortion in the reconstruction can be mostly reduced by using a highly curved beam for illumination in the data recording and forcing the dark field diffraction to be zero in the reconstruction.展开更多
Mixing and coherence are fundamental issues at the heart of understanding fluid dynamics and other non-autonomous dynamical systems. Recently the notion of coherence has come to a more rigorous footing, in particular,...Mixing and coherence are fundamental issues at the heart of understanding fluid dynamics and other non-autonomous dynamical systems. Recently the notion of coherence has come to a more rigorous footing, in particular, within the studies of finite-time nonautonomous dynamical systems. Here we recall “shape coherent sets” which is proven to correspond to slowly evolving curvature, for which tangency of finite time stable foliations (related to a “forward time” perspective) and finite time unstable foliations (related to a “backwards time” perspective) serve a central role. We compare and contrast this perspective to both the variational method of geodesics [17], as well as the coherent pairs perspective [12] from transfer operators.展开更多
Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system that differs from multiple sclerosis.Over the past 20 years,the search for biomarke rs for neuromyelitis optica has been ongo...Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system that differs from multiple sclerosis.Over the past 20 years,the search for biomarke rs for neuromyelitis optica has been ongoing.Here,we used a bibliometric approach to analyze the main research focus in the field of biomarkers for neuromyelitis optica.Research in this area is consistently increasing,with China and the United States leading the way on the number of studies conducted.The Mayo Clinic is a highly reputable institution in the United States,and was identified as the most authoritative institution in this field.Furthermore,Professor Wingerchuk from the Mayo Clinic was the most authoritative expe rt in this field.Keyword analysis revealed that the terms "neuro myelitis optica"(261 times), "multiple sclerosis"(220 times), "neuromyelitis optica spectrum disorder"(132 times), "aquaporin4"(99 times),and "optical neuritis"(87 times) were the most frequently used keywords in literature related to this field.Comprehensive analysis of the classical literature showed that the majority of publications provide conclusive research evidence supporting the use of aquaporin-4-IgG and neuromyelitis optica-IgG to effectively diagnose and differentiate neuromyelitis optica from multiple sclerosis.Furthermore,aquaporin-4-IgG has emerged as a highly specific diagnostic biomarker for neuromyelitis optica spectrum disorder.Myelin oligodendrocyte glycoprotein-IgG is a diagnostic biomarke r for myelin oligodendrocyte glycoprotein antibody-associated disease.Recent biomarkers for neuromyelitis optica in clude cerebrospinal fluid immunological biomarkers such as glial fibrillary acidic protein,serum astrocyte damage biomarkers like FAM19A5,serum albumin,and gammaaminobutyric acid.The latest prospective clinical trials are exploring the potential of these biomarkers.Preliminary results indicate that glial fibrillary acidic protein is emerging as a promising candidate biomarker for neuromyelitis optica spectrum disorder.The ultimate goal of future research is to identify non-invasive biomarkers with high sensitivity,specificity,and safety for the accurate diagnosis of neuro myelitis optica.展开更多
Limited by the dynamic range of the detector,saturation artifacts usually occur in optical coherence tomography(OCT)imaging for high scattering media.The available methods are difficult to remove saturation artifacts ...Limited by the dynamic range of the detector,saturation artifacts usually occur in optical coherence tomography(OCT)imaging for high scattering media.The available methods are difficult to remove saturation artifacts and restore texture completely in OCT images.We proposed a deep learning-based inpainting method of saturation artifacts in this paper.The generation mechanism of saturation artifacts was analyzed,and experimental and simulated datasets were built based on the mechanism.Enhanced super-resolution generative adversarial networks were trained by the clear–saturated phantom image pairs.The perfect reconstructed results of experimental zebrafish and thyroid OCT images proved its feasibility,strong generalization,and robustness.展开更多
AIM:To explore the usage of choroidal thickness measured by swept-source optical coherence tomography(SS-OCT)to detect myopic macular degeneration(MMD)in high myopic participants.METHODS:Participants with bilateral hi...AIM:To explore the usage of choroidal thickness measured by swept-source optical coherence tomography(SS-OCT)to detect myopic macular degeneration(MMD)in high myopic participants.METHODS:Participants with bilateral high myopia(≤−6 diopters)were recruited from a subset of the Guangzhou Zhongshan Ophthalmic Center-Brien Holden Vision Institute High Myopia Cohort Study.SS-OCT was performed to determine the choroidal thickness,and myopic maculopathy was graded by the International Meta-Analysis for Pathologic Myopia(META-PM)Classification.Presence of MMD was defined as META-PM category 2 or above.RESULTS:A total of 568 right eyes were included for analysis.Eyes with MMD(n=106,18.7%)were found to have older age,longer axial lengths(AL),higher myopic spherical equivalents(SE),and reduced choroidal thickness in each Early Treatment Diabetic Retinopathy Study(ETDRS)grid sector(P<0.001).The area under the receiver operating characteristic(ROC)curves(AUC)for subfoveal choroidal thickness(0.907)was greater than that of the model,including age,AL,and SE at 0.6249,0.8208,and 0.8205,respectively.The choroidal thickness of the inner and outer nasal sectors was the most accurate indicator of MMD(AUC of 0.928 and 0.923,respectively).An outer nasal sector choroidal thickness of less than 74μm demonstrated the highest odds of predicting MMD(OR=33.8).CONCLUSION:Choroidal thickness detects the presence of MMD with high agreement,particularly of the inner and outer nasal sectors of the posterior pole,which appears to be a biometric parameter more precise than age,AL,or SE.展开更多
Diamond,with ultrahigh hardness,high wear resistance,high thermal conductivity,and so forth,has attracted worldwide attention.However,researchers found emergent reactions at the interfaces between diamond and ferrous ...Diamond,with ultrahigh hardness,high wear resistance,high thermal conductivity,and so forth,has attracted worldwide attention.However,researchers found emergent reactions at the interfaces between diamond and ferrous materials,which significantly affects the performance of diamond-based devices.Herein,combing experiments and theoretical calculations,taking diamond–iron(Fe)interface as a prototype,the counter-diffusion mechanism of Fe/carbon atoms has been established.Surprisingly,it is identified that Fe and diamond first form a coherent interface,and then Fe atoms diffuse into diamond and prefer the carbon vacancies sites.Meanwhile,the relaxed carbon atoms diffuse into the Fe lattice,forming Fe_(3)C.Moreover,graphite is observed at the Fe_(3)C surface when Fe_(3)C is over-saturated by carbon atoms.The present findings are expected to offer new insights into the atomic mechanism for diamondferrous material's interfacial reactions,benefiting diamond-based device applications.展开更多
An innovative complex lidar system deployed on an airborne rotorcraft platform for remote sensing of atmospheric pollution is proposed and demonstrated.The system incorporates integrated-path differential absorption l...An innovative complex lidar system deployed on an airborne rotorcraft platform for remote sensing of atmospheric pollution is proposed and demonstrated.The system incorporates integrated-path differential absorption lidar(DIAL) and coherent-doppler lidar(CDL) techniques using a dual tunable TEA CO_(2)laser in the 9—11 μm band and a 1.55 μm fiber laser.By combining the principles of differential absorption detection and pulsed coherent detection,the system enables agile and remote sensing of atmospheric pollution.Extensive static tests validate the system’s real-time detection capabilities,including the measurement of concentration-path-length product(CL),front distance,and path wind speed of air pollution plumes over long distances exceeding 4 km.Flight experiments is conducted with the helicopter.Scanning of the pollutant concentration and the wind field is carried out in an approximately 1 km slant range over scanning angle ranges from 45°to 65°,with a radial resolution of 30 m and10 s.The test results demonstrate the system’s ability to spatially map atmospheric pollution plumes and predict their motion and dispersion patterns,thereby ensuring the protection of public safety.展开更多
There is a certain failure rate in traditional glaucoma surgery because of the lack of depth information in microscope images.In this work,we present a digital microscope-integrated optical coherence tomography(MIOCT)...There is a certain failure rate in traditional glaucoma surgery because of the lack of depth information in microscope images.In this work,we present a digital microscope-integrated optical coherence tomography(MIOCT)system and several custom-made OCT-compatible instruments for glaucoma surgery.Sixteen ophthalmologists were asked to perform trabeculectomy and canaloplasty on live porcine eyes using the system and instruments.After surgery,a subjective feedback survey about the user experience was taken.The experiment results showed that our system can help surgeons easily locate important tissue structures during surgery.The custom-made instruments also solved the shadowing problem in OCT imaging.Surgeons preferred to use the system in their future practice.展开更多
AIM:To evaluate the relationship of overweight and obesity with retinal and choroidal thickness in adults without ocular symptoms by swept-source optical coherence tomography(SS-OCT).METHODS:According to the body mass...AIM:To evaluate the relationship of overweight and obesity with retinal and choroidal thickness in adults without ocular symptoms by swept-source optical coherence tomography(SS-OCT).METHODS:According to the body mass index(BMI)results,the adults enrolled in the cross-sectional study were divided into the normal group(18.50≤BMI<25.00 kg/m^(2)),the overweight group(25.00≤BMI<30.00 kg/m^(2)),and the obesity group(BMI≥30.00 kg/m^(2)).The one-way ANOVA and the Chi-square test were used for comparisons.Pearson’s correlation analysis was used to evaluate the relationships between the measured variables.RESULTS:This research covered the left eyes of 3 groups of 434 age-and sex-matched subjects each:normal,overweight,and obesity.The mean BMI was 22.20±1.67,26.82±1.38,and 32.21±2.35 kg/m^(2) in normal,overweight and obesity groups,respectively.The choroid was significantly thinner in both the overweight and obesity groups compared to the normal group(P<0.05 for all),while the retinal thickness of the three groups did not differ significantly.Pearson’s correlation analysis showed that BMI was significantly negatively correlated with choroidal thickness,but no significant correlation was observed between BMI and retinal thickness.CONCLUSION:Choroidal thickness is decreased in people with overweight or obesity.Research on changes in choroidal thickness contributes to the understanding of the mechanisms of certain ocular disorders in overweight and obese adults.展开更多
AIM:To compare the three-dimensional choroidal vascularity index(CVI)and choroidal thickness between fellow eyes of acute primary angle-closure(F-APAC)and chronic primary angle-closure glaucoma(F-CPACG)and the eyes of...AIM:To compare the three-dimensional choroidal vascularity index(CVI)and choroidal thickness between fellow eyes of acute primary angle-closure(F-APAC)and chronic primary angle-closure glaucoma(F-CPACG)and the eyes of normal controls.METHODS:This study included 37 patients with unilateral APAC,37 with asymmetric CPACG without prior treatment,and 36 healthy participants.Using swept-source optical coherence tomography(SS-OCT),the macular and peripapillary choroidal thickness and three-dimensional CVI were measured and compared globally and sectorally.Pearson’s correlation analysis and multivariate regression models were used to evaluate choroidal thickness or CVI with related factors.RESULTS:The mean subfoveal CVIs were 0.35±0.10,0.33±0.09,and 0.29±0.04,and the mean subfoveal choroidal thickness were 315.62±52.92,306.22±59.29,and 262.69±45.55μm in the F-APAC,F-CPACG,and normal groups,respectively.All macular sectors showed significantly higher CVIs and choroidal thickness in the F-APAC and F-CPACG eyes than in the normal eyes(P<0.05),while there were no significant differences between the F-APAC and F-CPACG eyes.In the peripapillary region,the mean overall CVIs were 0.21±0.08,0.20±0.08,and 0.19±0.05,and the mean overall choroidal thickness were 180.45±54.18,174.82±50.67,and 176.18±37.94μm in the F-APAC,F-CPACG,and normal groups,respectively.There were no significant differences between any of the two groups in all peripapillary sectors.Younger age,shorter axial length,and the F-APAC or F-CPACG diagnosis were significantly associated with higher subfoveal CVI and thicker subfoveal choroidal thickness(P<0.05).CONCLUSION:The fellow eyes of unilateral APAC or asymmetric CPACG have higher macular CVI and choroidal thickness than those of the normal controls.Neither CVI nor choroidal thickness can distinguish between eyes predisposed to APAC or CPACG.A thicker choroid with a higher vascular volume may play a role in the pathogenesis of primary angle-closure glaucoma.展开更多
BACKGROUND No study has investigated the change regularity between age and subfoveal choroidal thickness(SFCT)in proliferative diabetic retinopathy(PDR).AIM To investigate the relationship between the SFCT and age in ...BACKGROUND No study has investigated the change regularity between age and subfoveal choroidal thickness(SFCT)in proliferative diabetic retinopathy(PDR).AIM To investigate the relationship between the SFCT and age in Chinese patients with PDR.METHODS This was a cross-sectional retrospective study.The participants were hospitalized individuals with type 2 diabetes who underwent vitrectomy for PDR.Contralateral eyes that met the criteria were included in the study.All necessary laboratory tests were performed at the time of admission.Central macular thickness(CMT)and SFCT were two quantitative assessments made using enhanced depth imaging optical coherence tomography.CMT was measured automatically and SFCT was measured manually with digital calipers provided by the Heidelberg Eye Explorer software.RESULTS The final analysis included a total of 234 individuals with PDR.The average age was 55.60 years old±10.03 years old,and 57.69%of the population was male.Univariate analysis revealed a significant negative connection between age and SFCT in patients with PDR[β=-2.44,95%confidence interval(95%CI):-3.46 to-1.42;P<0.0001].In the fully adjusted model,the correlation between SFCT and age remained steady(β=-1.68,95%CI:-2.97 to-0.39;P=0.0117).Spline smoothing showed that the relationship between SFCT and age in patients with PDR was non-linear,with an inflection point at 54 years of age.CONCLUSION Our findings suggest that age is a key determinant of choroidal thickness.The non-linear link between SFCT and age in PDR patients should be taken into account.展开更多
In this work,we present an intravascular dual-mode endoscopic system capable of both intravascular photoacoustic imaging(IVPAI)and intravascular optical coherence tomography(IVOCT)for recognizing spontaneous coronary ...In this work,we present an intravascular dual-mode endoscopic system capable of both intravascular photoacoustic imaging(IVPAI)and intravascular optical coherence tomography(IVOCT)for recognizing spontaneous coronary artery dissection(SCAD)phantoms.IVPAI provides high-resolution and high-penetration images of intramural hematoma(IMH)at different depths,so it is especially useful for imaging deep blood clots associated with imaging phantoms.IVOCT can readily visualize the double-lumen morphology of blood vessel walls to identify intimal tears.We also demonstrate the capability of this dual-mode endoscopic system using mimicking phantoms and biological samples of blood clots in ex vivo porcine arteries.The results of the experiments indicate that the combined IVPAI and IVOCT technique has the potential to provide a more accurate SCAD assessment method for clinical applications.展开更多
文摘The coarsening behavior of Cr precipitates in Cu-0.1Ag-0.5Cr alloy was investigated, and the effects of aging processes on the microstructure and properties were discussed. The results show that the radius for coherent/semi-coherent transition of the Cr precipitates is determined from TEM micrographs as 1545nm. The calculated value of critical radius for a particle begining to lose coherency is about 12.5nm. The coherent (r<15nm) precipitates are found to coarsen and become semi-coherent during the passage of low-angle boundaries during recovery. The passage of high-angle boundaries through semi-coherent precipitates during recrystallization occurs by migration of the particle, resulting in the precipitates maintaining semi-coherent with the new grain.
基金Research Fund for Communications in Western China Under Grant No. 200431800028
文摘Proper Orthogonal Decomposition (POD) provides a powerful modal transformation tool for stochastic dynamics. In this paper, coherency matrix-based proper orthogonal decomposition (CPOD) is presented as an innovative form of the POD based on cross power spectral density matrices. By introducing a discretizing scheme, the CPOD-based spectral representation method is obtained for use in stochastic simulation. Moreover, some criteria are proposed that allow the truncation order of CPOD to be conveniently determined. A numerical example to illustrate the application of the proposed method for the simulation of a wind velocity field is provided.
基金Supported by National Natural Science Foundation of China Under Grant No.90715005,No.NCET-07-0186 and No.200802860007
文摘Many studies have focused on horizontal ground motion, resulting in many coherency functions for horizontal ground motion while neglecting related problems arising from vertical ground motion. However, seismic events have demonstrated that the vertical components of ground motion sometimes govern the ultimate failure of structures. In this paper, a vertical coherency function model of spatial ground motion is proposed based on the Hao model and SMART 1 array records, and the validity of the model is demonstrated. The vertical coherency function model of spatial ground motion is also compared with the horizontal coherency function model, indicating that neither model exhibits isotropic characteristics. The value of the vertical coherency function has little correlation with that of the horizontal coherency function. However, the coherence of the vertical ground motion between a pair of stations decreases with their projection distance and the frequency of the ground motion. When the projection distance in the wave direction is greater than 800 meters, the coherency between the two points can be neglected.
基金sponsored by National Key S&T Project of China(No.2011ZX05004-003)the Research Program of RIPED(No.101002kt0b52135)
文摘Seismic coherence is used to detect discontinuities in underground media. However, strata with steeply dipping structures often produce false low coherence estimates and thus incorrect discontinuity characterization results. It is important to eliminate or reduce the effect of dipping on coherence estimates. To solve this problem, time-domain dip scanning is typically used to improve estimation of coherence in areas with steeply dipping structures. However, the accuracy of the time-domain estimation of dip is limited by the sampling interval. In contrast, the spectrum amplitude is not affected by the time delays in adjacent seismic traces caused by dipping structures. We propose a coherency algorithm that uses the spectral amplitudes of seismic traces within a predefined analysis window to construct the covariance matrix. The coherency estimates with the proposed algorithm is defined as the ratio between the dominant the constructed covariance matrix. Thus, we eigenvalue and the sum of all eigenvalues of eliminate the effect of dipping structures on coherency estimates. In addition, because different frequency bands of spectral amplitudes are used to estimate coherency, the proposed algorithm has multiscale features. Low frequencies are effective for characterizing large-scale faults, whereas high frequencies are better in characterizing small-scale faults. Application to synthetic and real seismic data show that the proposed algorithm can eliminate the effect of dip and produce better coherence estimates than conventional coherency algorithms in areas with steeply dipping structures.
基金National Natural Science Foundation of China (59895410)
文摘At present, the method to study spatial variation of ground motions is statistic analysis based on dense array re-cords such as SMART-1 array, etc. For lacking of information of ground motions, there is no coherency function model of base rock and different style site. Spatial variation of ground motions in elastic media is analyzed by deterministic method in this paper. Taking elastic half-space model with dislocation source of fault, near-field ground motions are simulated. This model takes strike-slip fault and earth media into account. A coherency func-tion is proposed for base rock site.
文摘This paper analyzes cache coherency mechanism from the view of system. It firstly discusses caehe-memory hierarchy of Pentium Ⅲ SMP system, including memory area distribution, cache attributes control and bus transaction. Secondly it analyzes hardware snoopy mechanism of P6 bus and MESI state transitions adopted by Pentium Ⅲ. Based on these, it focuses on how muhiprocessors and the P6 bus cooperate to ensure cache coherency of the whole system, and gives the key of cache coherency design.
文摘The procerebrum (PC) of the land slug Limax is the olfactory center involved in olfactory discrimination and learning. In the PC, an oscillation of local field potential (LFP) with 0.5 - 1 Hz is observed by electrophysiological extracellular recording. Additionally, spatiotemporal neural activities in the PC have been examined using optical recordings. However, extracellular recording is preferable to measure neural activities for a long time with a high speed, while it is not abundant in spatial information. In this study, we therefore attempted to elicit spatial information from extracellular recording. For this purpose, we evaluated spatial information included in the LFP compared with the spatiotemporal neural activities measured by the fluorescent voltage imaging. As a result, aversive odors induced the coherent spatiotemporal neural activities in the PC, and the increase in coherency was observed as a change in the LFP waveform. It was also evaluated as a decrease in entropy by analyzing the LFP oscillation patterns and wavelet analysis. Thus, although the LFP provides only one series of signals, the coherency of the spatiotemporal neural activities in the PC can be evaluated by applying extracellular recording with wavelet analysis.
基金The research was under the construction of the Naquseismic array of Chinese Digital Seismography Observation Networkin National 10th Five-Year Program.
文摘The waveform data recorded during the site survey of the Naqu seismic array in Aug. 2004 were processed by the author. According to the relativity of site pairs in time and frequency domains, the reference values of the inner ring and outer ring were determined. The author evaluated the array deployed for site survey as the primary array, and the results show that the resolution of the primary array is high enough to locate earthquakes precisely.
基金supported by the Funds from the Engineering and Physical Sciences Research Council(Grant No.EP/E034055/1)the One Hundred Talent Project of the Chinese Academy of Sciences and the Financial Support(Grant No.GFZX0205010502.12)
文摘While ptychography is an algorithm based on coherent illumination,satisfactory reconstructions can still be generated in most experiments,even though the radiation sources that are used are not ideally coherent.The underlying physics of this phenomenon is that the diffraction patterns of partially coherent illumination can be treated as those of purely coherent illumination by altering the intensities of the diffracted beams relative to their real values.On the other hand,due to the inconsistency in the altering interference among all the diffraction beams,noise/distortion is always involved in the reconstructed images.Furthermore,for a weak object,the noise/distortion in the reconstruction can be mostly reduced by using a highly curved beam for illumination in the data recording and forcing the dark field diffraction to be zero in the reconstruction.
文摘Mixing and coherence are fundamental issues at the heart of understanding fluid dynamics and other non-autonomous dynamical systems. Recently the notion of coherence has come to a more rigorous footing, in particular, within the studies of finite-time nonautonomous dynamical systems. Here we recall “shape coherent sets” which is proven to correspond to slowly evolving curvature, for which tangency of finite time stable foliations (related to a “forward time” perspective) and finite time unstable foliations (related to a “backwards time” perspective) serve a central role. We compare and contrast this perspective to both the variational method of geodesics [17], as well as the coherent pairs perspective [12] from transfer operators.
文摘Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system that differs from multiple sclerosis.Over the past 20 years,the search for biomarke rs for neuromyelitis optica has been ongoing.Here,we used a bibliometric approach to analyze the main research focus in the field of biomarkers for neuromyelitis optica.Research in this area is consistently increasing,with China and the United States leading the way on the number of studies conducted.The Mayo Clinic is a highly reputable institution in the United States,and was identified as the most authoritative institution in this field.Furthermore,Professor Wingerchuk from the Mayo Clinic was the most authoritative expe rt in this field.Keyword analysis revealed that the terms "neuro myelitis optica"(261 times), "multiple sclerosis"(220 times), "neuromyelitis optica spectrum disorder"(132 times), "aquaporin4"(99 times),and "optical neuritis"(87 times) were the most frequently used keywords in literature related to this field.Comprehensive analysis of the classical literature showed that the majority of publications provide conclusive research evidence supporting the use of aquaporin-4-IgG and neuromyelitis optica-IgG to effectively diagnose and differentiate neuromyelitis optica from multiple sclerosis.Furthermore,aquaporin-4-IgG has emerged as a highly specific diagnostic biomarker for neuromyelitis optica spectrum disorder.Myelin oligodendrocyte glycoprotein-IgG is a diagnostic biomarke r for myelin oligodendrocyte glycoprotein antibody-associated disease.Recent biomarkers for neuromyelitis optica in clude cerebrospinal fluid immunological biomarkers such as glial fibrillary acidic protein,serum astrocyte damage biomarkers like FAM19A5,serum albumin,and gammaaminobutyric acid.The latest prospective clinical trials are exploring the potential of these biomarkers.Preliminary results indicate that glial fibrillary acidic protein is emerging as a promising candidate biomarker for neuromyelitis optica spectrum disorder.The ultimate goal of future research is to identify non-invasive biomarkers with high sensitivity,specificity,and safety for the accurate diagnosis of neuro myelitis optica.
基金supported by the National Natural Science Foundation of China(62375144 and 61875092)Tianjin Foundation of Natural Science(21JCYBJC00260)Beijing-Tianjin-Hebei Basic Research Cooperation Special Program(19JCZDJC65300).
文摘Limited by the dynamic range of the detector,saturation artifacts usually occur in optical coherence tomography(OCT)imaging for high scattering media.The available methods are difficult to remove saturation artifacts and restore texture completely in OCT images.We proposed a deep learning-based inpainting method of saturation artifacts in this paper.The generation mechanism of saturation artifacts was analyzed,and experimental and simulated datasets were built based on the mechanism.Enhanced super-resolution generative adversarial networks were trained by the clear–saturated phantom image pairs.The perfect reconstructed results of experimental zebrafish and thyroid OCT images proved its feasibility,strong generalization,and robustness.
基金Supported by the National Natural Science Foundation of China(No.82301249,No.82371086)the Science and Technology Projects in Guangzhou(No.SL2024A04J01756)the Fundamental Research Funds of the State Key Laboratory of Ophthalmology(No.83000-32030003).
文摘AIM:To explore the usage of choroidal thickness measured by swept-source optical coherence tomography(SS-OCT)to detect myopic macular degeneration(MMD)in high myopic participants.METHODS:Participants with bilateral high myopia(≤−6 diopters)were recruited from a subset of the Guangzhou Zhongshan Ophthalmic Center-Brien Holden Vision Institute High Myopia Cohort Study.SS-OCT was performed to determine the choroidal thickness,and myopic maculopathy was graded by the International Meta-Analysis for Pathologic Myopia(META-PM)Classification.Presence of MMD was defined as META-PM category 2 or above.RESULTS:A total of 568 right eyes were included for analysis.Eyes with MMD(n=106,18.7%)were found to have older age,longer axial lengths(AL),higher myopic spherical equivalents(SE),and reduced choroidal thickness in each Early Treatment Diabetic Retinopathy Study(ETDRS)grid sector(P<0.001).The area under the receiver operating characteristic(ROC)curves(AUC)for subfoveal choroidal thickness(0.907)was greater than that of the model,including age,AL,and SE at 0.6249,0.8208,and 0.8205,respectively.The choroidal thickness of the inner and outer nasal sectors was the most accurate indicator of MMD(AUC of 0.928 and 0.923,respectively).An outer nasal sector choroidal thickness of less than 74μm demonstrated the highest odds of predicting MMD(OR=33.8).CONCLUSION:Choroidal thickness detects the presence of MMD with high agreement,particularly of the inner and outer nasal sectors of the posterior pole,which appears to be a biometric parameter more precise than age,AL,or SE.
基金supported by the National Natural Science Foundation of China(Grant Nos.12274371,62271450,U21A2070,21805247,12074345)Cross-Disciplinary Innovative Research Group Project of Henan Province(Grant No.232300421004).
文摘Diamond,with ultrahigh hardness,high wear resistance,high thermal conductivity,and so forth,has attracted worldwide attention.However,researchers found emergent reactions at the interfaces between diamond and ferrous materials,which significantly affects the performance of diamond-based devices.Herein,combing experiments and theoretical calculations,taking diamond–iron(Fe)interface as a prototype,the counter-diffusion mechanism of Fe/carbon atoms has been established.Surprisingly,it is identified that Fe and diamond first form a coherent interface,and then Fe atoms diffuse into diamond and prefer the carbon vacancies sites.Meanwhile,the relaxed carbon atoms diffuse into the Fe lattice,forming Fe_(3)C.Moreover,graphite is observed at the Fe_(3)C surface when Fe_(3)C is over-saturated by carbon atoms.The present findings are expected to offer new insights into the atomic mechanism for diamondferrous material's interfacial reactions,benefiting diamond-based device applications.
文摘An innovative complex lidar system deployed on an airborne rotorcraft platform for remote sensing of atmospheric pollution is proposed and demonstrated.The system incorporates integrated-path differential absorption lidar(DIAL) and coherent-doppler lidar(CDL) techniques using a dual tunable TEA CO_(2)laser in the 9—11 μm band and a 1.55 μm fiber laser.By combining the principles of differential absorption detection and pulsed coherent detection,the system enables agile and remote sensing of atmospheric pollution.Extensive static tests validate the system’s real-time detection capabilities,including the measurement of concentration-path-length product(CL),front distance,and path wind speed of air pollution plumes over long distances exceeding 4 km.Flight experiments is conducted with the helicopter.Scanning of the pollutant concentration and the wind field is carried out in an approximately 1 km slant range over scanning angle ranges from 45°to 65°,with a radial resolution of 30 m and10 s.The test results demonstrate the system’s ability to spatially map atmospheric pollution plumes and predict their motion and dispersion patterns,thereby ensuring the protection of public safety.
基金support of the foundations:National Key R&D Program of China,Grant Nos.2022YFC2404201CAS Project for Young Scientists in Basic Research,Grant Nos.YSBR-067+2 种基金The Gusu Innovation and Entrepreneurship Leading Talents in Suzhou City,Grant Nos.ZXL2021425Jiangsu Science and Technology Plan Program,Grant Nos.BK20220263National Key R&D Program of China,Grant Nos.2021YFF0700503.
文摘There is a certain failure rate in traditional glaucoma surgery because of the lack of depth information in microscope images.In this work,we present a digital microscope-integrated optical coherence tomography(MIOCT)system and several custom-made OCT-compatible instruments for glaucoma surgery.Sixteen ophthalmologists were asked to perform trabeculectomy and canaloplasty on live porcine eyes using the system and instruments.After surgery,a subjective feedback survey about the user experience was taken.The experiment results showed that our system can help surgeons easily locate important tissue structures during surgery.The custom-made instruments also solved the shadowing problem in OCT imaging.Surgeons preferred to use the system in their future practice.
基金Supported by the Science and Technology Commission of Shanghai Municipality(No.20Y11910800).
文摘AIM:To evaluate the relationship of overweight and obesity with retinal and choroidal thickness in adults without ocular symptoms by swept-source optical coherence tomography(SS-OCT).METHODS:According to the body mass index(BMI)results,the adults enrolled in the cross-sectional study were divided into the normal group(18.50≤BMI<25.00 kg/m^(2)),the overweight group(25.00≤BMI<30.00 kg/m^(2)),and the obesity group(BMI≥30.00 kg/m^(2)).The one-way ANOVA and the Chi-square test were used for comparisons.Pearson’s correlation analysis was used to evaluate the relationships between the measured variables.RESULTS:This research covered the left eyes of 3 groups of 434 age-and sex-matched subjects each:normal,overweight,and obesity.The mean BMI was 22.20±1.67,26.82±1.38,and 32.21±2.35 kg/m^(2) in normal,overweight and obesity groups,respectively.The choroid was significantly thinner in both the overweight and obesity groups compared to the normal group(P<0.05 for all),while the retinal thickness of the three groups did not differ significantly.Pearson’s correlation analysis showed that BMI was significantly negatively correlated with choroidal thickness,but no significant correlation was observed between BMI and retinal thickness.CONCLUSION:Choroidal thickness is decreased in people with overweight or obesity.Research on changes in choroidal thickness contributes to the understanding of the mechanisms of certain ocular disorders in overweight and obese adults.
基金Supported by the National Natural Science Foundation of China(No.82101087)Shanghai Clinical Research Key Project(No.SHDC2020CR6029).
文摘AIM:To compare the three-dimensional choroidal vascularity index(CVI)and choroidal thickness between fellow eyes of acute primary angle-closure(F-APAC)and chronic primary angle-closure glaucoma(F-CPACG)and the eyes of normal controls.METHODS:This study included 37 patients with unilateral APAC,37 with asymmetric CPACG without prior treatment,and 36 healthy participants.Using swept-source optical coherence tomography(SS-OCT),the macular and peripapillary choroidal thickness and three-dimensional CVI were measured and compared globally and sectorally.Pearson’s correlation analysis and multivariate regression models were used to evaluate choroidal thickness or CVI with related factors.RESULTS:The mean subfoveal CVIs were 0.35±0.10,0.33±0.09,and 0.29±0.04,and the mean subfoveal choroidal thickness were 315.62±52.92,306.22±59.29,and 262.69±45.55μm in the F-APAC,F-CPACG,and normal groups,respectively.All macular sectors showed significantly higher CVIs and choroidal thickness in the F-APAC and F-CPACG eyes than in the normal eyes(P<0.05),while there were no significant differences between the F-APAC and F-CPACG eyes.In the peripapillary region,the mean overall CVIs were 0.21±0.08,0.20±0.08,and 0.19±0.05,and the mean overall choroidal thickness were 180.45±54.18,174.82±50.67,and 176.18±37.94μm in the F-APAC,F-CPACG,and normal groups,respectively.There were no significant differences between any of the two groups in all peripapillary sectors.Younger age,shorter axial length,and the F-APAC or F-CPACG diagnosis were significantly associated with higher subfoveal CVI and thicker subfoveal choroidal thickness(P<0.05).CONCLUSION:The fellow eyes of unilateral APAC or asymmetric CPACG have higher macular CVI and choroidal thickness than those of the normal controls.Neither CVI nor choroidal thickness can distinguish between eyes predisposed to APAC or CPACG.A thicker choroid with a higher vascular volume may play a role in the pathogenesis of primary angle-closure glaucoma.
基金Supported by the 1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University,No.ZYJC21025.
文摘BACKGROUND No study has investigated the change regularity between age and subfoveal choroidal thickness(SFCT)in proliferative diabetic retinopathy(PDR).AIM To investigate the relationship between the SFCT and age in Chinese patients with PDR.METHODS This was a cross-sectional retrospective study.The participants were hospitalized individuals with type 2 diabetes who underwent vitrectomy for PDR.Contralateral eyes that met the criteria were included in the study.All necessary laboratory tests were performed at the time of admission.Central macular thickness(CMT)and SFCT were two quantitative assessments made using enhanced depth imaging optical coherence tomography.CMT was measured automatically and SFCT was measured manually with digital calipers provided by the Heidelberg Eye Explorer software.RESULTS The final analysis included a total of 234 individuals with PDR.The average age was 55.60 years old±10.03 years old,and 57.69%of the population was male.Univariate analysis revealed a significant negative connection between age and SFCT in patients with PDR[β=-2.44,95%confidence interval(95%CI):-3.46 to-1.42;P<0.0001].In the fully adjusted model,the correlation between SFCT and age remained steady(β=-1.68,95%CI:-2.97 to-0.39;P=0.0117).Spline smoothing showed that the relationship between SFCT and age in patients with PDR was non-linear,with an inflection point at 54 years of age.CONCLUSION Our findings suggest that age is a key determinant of choroidal thickness.The non-linear link between SFCT and age in PDR patients should be taken into account.
基金funding from the National Natural Science Foundation of China(NSFC)under grants 61627827,61705068the Natural Science Foundation of Fujian Province 2021J01813the Fujian Medical University Research Foundation of Talented Scholars XRCZX2021004.
文摘In this work,we present an intravascular dual-mode endoscopic system capable of both intravascular photoacoustic imaging(IVPAI)and intravascular optical coherence tomography(IVOCT)for recognizing spontaneous coronary artery dissection(SCAD)phantoms.IVPAI provides high-resolution and high-penetration images of intramural hematoma(IMH)at different depths,so it is especially useful for imaging deep blood clots associated with imaging phantoms.IVOCT can readily visualize the double-lumen morphology of blood vessel walls to identify intimal tears.We also demonstrate the capability of this dual-mode endoscopic system using mimicking phantoms and biological samples of blood clots in ex vivo porcine arteries.The results of the experiments indicate that the combined IVPAI and IVOCT technique has the potential to provide a more accurate SCAD assessment method for clinical applications.