The combined selection index used in the breeding of new Yorkshire dam line with high prolificacy according to breeding objects was formulated as /：2.272E- BVNB-0.056EBVDAYS. After 5 generations breeding, the two mai...The combined selection index used in the breeding of new Yorkshire dam line with high prolificacy according to breeding objects was formulated as /：2.272E- BVNB-0.056EBVDAYS. After 5 generations breeding, the two main selected traits such as total number of born and age at 100 kg weight was 12.17 piglets/litter and 165.18 d, respectively. The genetic improvements per generates was 0.156 and -2.198, respec- tively. The breeding objects of the new Yorkshire dam line with high prolificacy were basically reached. It indicated that the methods and index could be used in pig breeding.展开更多
【目的】观察多西他赛联合奥沙利铂与替加氟方案治疗晚期胃癌的临床疗效和不良反应。【方法】32例均经病理组织学诊断为胃癌，初治病例18例，复治病例14例，每例均完成至少2个周期化疗。治疗方案：多西他赛75 mg／m2，d1，静滴2 h；奥...【目的】观察多西他赛联合奥沙利铂与替加氟方案治疗晚期胃癌的临床疗效和不良反应。【方法】32例均经病理组织学诊断为胃癌，初治病例18例，复治病例14例，每例均完成至少2个周期化疗。治疗方案：多西他赛75 mg／m2，d1，静滴2 h；奥沙利铂130 mg／m2，d2，静滴；替加氟800 mg／m2，微量泵持续静滴，维持22 h ，d2～3，21 d为一周期。【结果】32例患者总有效率为17例（53．1％），中位肿瘤进展时间（T T P ）13个月，不良反应为白细胞下降24例（75．0％），恶心，呕吐21例（65．6％），周围神经毒性13例（40．6％），脱发10例（31．3％）。【结论】多西他赛联合奥沙利铂与替加氟方案治疗晚期胃癌临床疗效好，不良反应可耐受。展开更多
This paper presents formulae and explanation about the growth of a convective gas bubble in the blood and other tissues of divers who surface too quickly, concentration distribution around the growing bubble is also p...This paper presents formulae and explanation about the growth of a convective gas bubble in the blood and other tissues of divers who surface too quickly, concentration distribution around the growing bubble is also presented. The formulae are valid all over the growth stages, i.e. under variable ambient pressure while the diver is ascending, and under constant ambient pressure at diving stops or at sea level. The mathematical model is solved analytically by using the method of combined variables. The growth process is affected by tissue diffusivity, concentration constant and the initial void fraction, which is the dominant parameter. Results show that, the time of the complete growth, in the convective growth model, is shorter than those earlier presented by Mohammadein and Mohamed [Concentration distribution around a growing gas bubble in tissue, Math. Biosci. 225（1） （2010） 11-17] and Srinivasan et al. [Mathematical models of diffusion- limited gas bubble dynamics in tissue, J. Appl. Physiol. 86 （1999） 732-741] for the growth of a stationary gas bubble, this explains the effect of bubble motion on consuming the oversaturated dissolved gas from the tissue into growing bubble which leads to increment in the growth rate to be more than those presented in the previous stationary models.展开更多
基金Supported by National Science and Technology Support Plan during the Eleventh Five-year Plan(2006BAD01A08-02)Hubei Agricultural Innovation Program(2007-620-004-003)Special Fund for Modern Pig Production Technology Construction(NYCYTX-009)~~
文摘The combined selection index used in the breeding of new Yorkshire dam line with high prolificacy according to breeding objects was formulated as /：2.272E- BVNB-0.056EBVDAYS. After 5 generations breeding, the two main selected traits such as total number of born and age at 100 kg weight was 12.17 piglets/litter and 165.18 d, respectively. The genetic improvements per generates was 0.156 and -2.198, respec- tively. The breeding objects of the new Yorkshire dam line with high prolificacy were basically reached. It indicated that the methods and index could be used in pig breeding.
文摘【目的】观察多西他赛联合奥沙利铂与替加氟方案治疗晚期胃癌的临床疗效和不良反应。【方法】32例均经病理组织学诊断为胃癌，初治病例18例，复治病例14例，每例均完成至少2个周期化疗。治疗方案：多西他赛75 mg／m2，d1，静滴2 h；奥沙利铂130 mg／m2，d2，静滴；替加氟800 mg／m2，微量泵持续静滴，维持22 h ，d2～3，21 d为一周期。【结果】32例患者总有效率为17例（53．1％），中位肿瘤进展时间（T T P ）13个月，不良反应为白细胞下降24例（75．0％），恶心，呕吐21例（65．6％），周围神经毒性13例（40．6％），脱发10例（31．3％）。【结论】多西他赛联合奥沙利铂与替加氟方案治疗晚期胃癌临床疗效好，不良反应可耐受。
文摘This paper presents formulae and explanation about the growth of a convective gas bubble in the blood and other tissues of divers who surface too quickly, concentration distribution around the growing bubble is also presented. The formulae are valid all over the growth stages, i.e. under variable ambient pressure while the diver is ascending, and under constant ambient pressure at diving stops or at sea level. The mathematical model is solved analytically by using the method of combined variables. The growth process is affected by tissue diffusivity, concentration constant and the initial void fraction, which is the dominant parameter. Results show that, the time of the complete growth, in the convective growth model, is shorter than those earlier presented by Mohammadein and Mohamed [Concentration distribution around a growing gas bubble in tissue, Math. Biosci. 225（1） （2010） 11-17] and Srinivasan et al. [Mathematical models of diffusion- limited gas bubble dynamics in tissue, J. Appl. Physiol. 86 （1999） 732-741] for the growth of a stationary gas bubble, this explains the effect of bubble motion on consuming the oversaturated dissolved gas from the tissue into growing bubble which leads to increment in the growth rate to be more than those presented in the previous stationary models.
