Analysis on Combining Ability and Heritability of the Main Agronomic Characters for JA CMS in Brassica napus L.

Fifteen combinations crossed by five JA cytoplasmic male sterile lines （A1, A2, A3, A4, A5） and three restoring lines （R1, R2, R3） were selected to analyze the combining ability and heritability of nine main agronomic characters of Brassica na-pus L. to definite the application potential of these parent materials. The result showed that （i） the general combining ability （GCA） of male parents was R3＆gt;R2＆gt;R1 and that of female parents was A4＆gt;A1＆gt;A2＆gt;A5＆gt;A3; （i ） the special combining ability （SCA） of A2＆#215;R3 in plant height, number of branches, number of pods per plant and yield per plant was the best. The yield per plant of A2＆#215;R3, A1＆#215;R1 and A2＆#215;R1 ranked the first three places in the 15 combinations; （i i） the broad heritability of yield per plant was the highest, and that of the height of branches was the lowest. The com-prehensive characters of R3, A2 and A4 were better, which could be used to create new materials; （iv） good offspring were more likely to be chosen from the combina-tion with higher parental GCA, so the GCA and SCA should be considered com-prehensively when choosing parent and determining the optimal combinations.

Analysis on Heterosis and Combining Ability of Main Agronomic Characteristics in Huang-Huai-Hai Summer Soybean

With 10 elite soybean varieties from Huang-Huai-Hai Valleys as materials,25 hybridization combinations were compounded based on NC II,and the heterosis and combining ability for the major agronomic characters in summer soybean was studied.The results showed that heterosis of agronomic traits of soybean was ubiquity,and the average heterosis of all characters showed positive advantages.The advantage of seed weight per plant,number of seeds per plant and number of pods per plant were the highest,at 35.58%,34.23%and 31.47%,respectively,and thus made a great contribution to yield heterosis.The general combining ability of Hedou 19,Handou 6,Shanning 14 and Williams 82 was relatively higher in seed weight per plant,number of seeds per plant and number of pods per plant,and they are quality parents for designing strong hybridization combinations.There were significant differences in special combining ability(SCA)among parents for the same trait in different combinations.Some showed positive effect,and others showed negative effects.We should select the best combination according to breeding objective in selecting and matching special elite combinations.

Temperament and character as predictor of health related quality of life after metacarpophalangeal joint arthroplasty ——Personality and MCP joint arthroplasty outcome

Purpose: To evaluate personality characteris- tics’ impact upon outcome after silicone-based MP arthroplasty in RA patients. Methods: 40 RA patients who had undergone operations on their MP joints were investigated in a one-year fol- low-up. Objective measurement to assess grip strength and active range of motion—Paper- pencil-tests to assess pain during activity and at rest performance, QoL, and personality. Results: Significant improvement was observed in func- tion and pain related scores except for the pain related VAS and in several QoL facets and do- mains. Patients who experienced improvement reported higher scores on the activities of daily living facet of the WHO QoL questionnaire. Those with lower pain showed more independ- ence. The variance of the QoL domain scores, other than social and physical domains, could substantially and meaningfully be explained by variance of objective measures combined with personality scores. Conclusions: Most RA pa- tients’ QoL can be improved by MP arthroplasty despite remaining substantial level of pain. NS and HA seem to play an important role in the adaptation process during the long term, chronic illness;whereas SD represents a tool of coping with the burden of pain and disability. Personal- ity characteristics are highly predictive for QoL suggesting their important mediating role be- tween experienced pain and disability and HR QoL.

Adjuvant hormone therapy after radical prostatectomy in highrisk localized and locally advanced prostate cancer: First multicenter, observational study in China

Objective: Potential of combined androgen blockade(CAB) has not been explored extensively in Chinese males with prostate cancer(PCa). Therefore, this study evaluated the 2-year prostate-specific antigen(PSA) recurrence rate and quality of life(Qo L) in patients with high-risk localized and locally advanced PCa receiving adjuvant hormone therapy(HT) after radical prostatectomy(RP).Methods: This prospective, multicenter, observational study conducted in 18 centers across China enrolled patients with high-risk factor(preoperative PSA>20 ng/m L or Gleason score >7) or locally advanced PCa. Different adjuvant HT were administered after RP according to investigator’s decision in routine clinical practice.Relationship of baseline and postoperative characteristics was assessed with recurrence rate. PSA recurrence rate and Functional Assessment of Cancer Therapy-Prostate(FACT-P) Qo L scores were recorded at 12 months and 24 months. Kaplan-Meier analysis was used to construct the PSA recurrence rate during follow-up.Results: A total of 189 patients(mean age: 66.9±6.5 years) were recruited, among which 112(59.3%) patients showed serum PSA>20 ng/m L preoperatively. The highest postoperative pathological advancement noticed was from clinical T2(c T2) to pathological T3(p T3)(43.9%) stage. The majority of the patients(66.1%) received CAB as adjuvant HT, for a median duration of 20.0 months. The least recurrence(15.2%) was noticed in patients treated with CAB, followed by those treated with luteinizing hormone-releasing hormone agonist(LHRHa)(16.1%), and antiandrogen(19.0%), with non-significant difference noted among the groups. None of the baseline or postoperative characteristics was related with PSA recurrence in our study. The 24-month FACT-P Qo L score of119 patients treated for >12 months showed significant improvement above baseline compared with those treated for ≤12 months.Conclusions: Adjuvant CAB therapy after RP showed reduction trend in 2-year PSA recurrence rate in highrisk Chinese patients with localized and locally advanced PCa, compared with adjuvant anti-androgens(AA) or LHRHa therapy. Further long-term therapy(>12 months) significantly improved Qo L compared to short-term HT therapy, suggesting the beneficial effect of long-term CAB therapy in improving Qo L.

Effectiveness and postoperative rehabilitation of one-stage combined anterior-posterior surgery for severe thoracolumbar fractures with spinal cord injury

BACKGROUND Thoracolumbar fractures are generally combined with spinal cord injury to varying degrees,which may cause deterioration of the patients’condition and increase the difficulty of clinical treatment.At present,anterior or combined anterior-posterior surgery is preferred for severe thoracolumbar fractures.AIM To investigate the effectiveness and postoperative rehabilitation of one-stage combined anterior-posterior surgery for severe thoracolumbar fractures with spinal cord injury.METHODS One-hundred-and-twenty patients who received surgery for severe thoracolumbar fractures with spinal cord injury at our hospital from February 2018 to February 2020 were randomly enrolled.They were randomly divided into group 1(one-stage combined anterior-posterior surgery,n=60)and group 2(onestage anterior-approach surgery,n=60).Treatment efficacy was compared between the two groups.RESULTS Blood loss was greater and the operation time was longer in group 1 than in group 2,and the differences were statistically significant(P<0.05).Incision length,intraoperative X-rays,and length of hospital stay were not significantly different between the two groups(P>0.05).Preoperative function of the affected vertebrae was not significantly different between the two groups(P>0.05).In each group,the patients showed significant improvement after surgery.The anterior vertebral height ratio and the posterior vertebral height ratio in group 1 after surgery were significantly higher than those in group 2.The Cobb angle after surgery was significantly lower in group 1 than in group 2(P<0.05).The canal-occupying ratio of the affected vertebrae was not significantly different between the two groups(P>0.05).Before surgery,there was no significant difference in the quality of life scores between the two groups(P>0.05).The above indicators were significantly improved after surgery compared with before surgery in each group.In addition,these indicators were markedly better in group 1 than in group 2 after surgery(P<0.05 for each).CONCLUSION One-stage combined anterior-posterior surgery effectively improves the function of the affected vertebrae and the life quality of patients with severe thoracolumbar fractures and spinal cord injury.This surgical approach is worthy of popularization in clinical use.

Analysis on Combining Ability for Characters of Male Sterile Lines in Rapeseed(Brassica napus L.)

The male sterile line is very important in the hybrid breeding program of rapeseed. This study was conducted to evaluate the combining ability of many characters of male sterile lines in Brassica napus L. Ten recessive genetic male sterile （RGMS） lines were used as parents to produce 45 single cross hybrids by using a half diallel cross method. These 45 crosses and their 10 parents were evaluated at Guiyang during 2007-2008. The results showed that both general combining ability （GCA） and specific combiing ability （SCA） effects were important for all characters, but additive gene effects were more predominant than non-additive gene effects. Qianyou 8AB and You 2894AB gave respective highly significant GCA effects of 230.94 and 127.65 kg-hm-2 for seed yield. Lines You 2894AB, QH303-4AB, You 157AB and You 2341AB gave highly significant GCA effects for oil content of 0.99, 1.62, 1.20 and 1.53%, respectively. The crosses among lines Qianyou 3AxQianyou 8B, Qianyou 8AxYou 2894B, You 2894AxQianyou 6B, Qianyou 8AxQH303-4B and Qianyou 8Ax Qianyou 6B gave high SCA effects of 616.29, 398.71,356.48, 394.24 and 303.79 kg hm-2 for seed yield, respectively. All these crosses also gave high seed yield indicating that these crosses could be used in the breeding program.

Establishment of wear model and life prediction of drum of hot rolling coiler

For the drum of hot rolling coiler is prone to be easily destroyed, the type of MMU-5G abrasion tester was applied to revealing the friction and wear behavior. The morphology observation by scanning electron microscope (SEM) demonstrates the wear mechanism of the drum, and the test data of the influence coefficient of the normal pressure, relative sliding speed and surface lubrication conditions acted on the linear rate of the wear could be obtained by the regression method. A calculation model, which considers the factors of the structure of the drum, coiling tension and coiling strip specifications, was established by the combination method to predict the wear life of the drum. Then the practical production data was applied into this model and the analysis result was in good accordance with that of actual production.

Effect of TCM Combined with Chemotherapy on Immune Function and Quality of Life of Patients with Non-small Cell Lung Cancer inStage Ⅲ-Ⅳ

Objective: To observe and compare the effect of traditional Chinese medicine (TCM) combined with chemotherapy (CT) on immune function and quality of life (QOL)of patients with non-small cell lung cancer (NSCLC) in stage Ⅲ-Ⅳ. Methods: One hundred cases with stage Ⅲ-Ⅳ NSCLC were randomly divided into two groups. The treated group (n=50) received CT combined with TCM, and the control group received CT alone. The percentage of T lymphocyte subset in peripheral blood and the change of natural killer (NK) cell count were observed after treatment. The QOL and tolerance of CT were also compared between the two groups after treatment. Results: In the treated group, CD3 cell count, CD4 cell count, CD4/ CDg ratio and NK cell activity were higher than those in control group, while CD8 cell count in the treated group was lower than that in the control group (P<0.05), and QOL and tolerance of CT in the treated group were also better (P<0.05). Conclusion: TCM combined with CT could raise the patients' ability in tolerating CT in stage Ⅲ-ⅣNSCLC.

Fatigue Life of Slewing Bearings under Combined Radial,Axial and Tilting Moment Loads

A calculation method of fatigue life for slewing bearings under combined radial, axial and tilting moment loads was proposed. Single row four-point contact ball slewing bearing being used as a case, the statics model of the slewing bearing was established and a set of equilibrium equations were obtained. By solving the equilibrium equatioas, the rolling element loads were obtained and the equivalent rolling element loads were calculated further. By using the geometrical parameters of the bearing, the rating rolling element loads were calculated, and the fa- tigue life of the bearing was calculated by using the rating rolling element loads and the equivalent rolling element loads. A calculation example shows the feasibility of the proposed method.

Research on the Integration of Structural Design and Material Parameters of Long-life Asphalt Pavement

In order to reduce the disease risk stemming from asphalt concrete pavement and ensure the safety of road operation,we should pay attention to the structural design of long-life asphalt pavement,strengthen the selection of long-term pavement materials,scientifically set the pavement mechanical performance indexes based on the calculation results of pavement structure thickness combination and modulus combination,and ensure the stability and durability of road pavement structure through the real-time establishment of three-dimensional finite element calculation model,as well as the integrated design that takes into consideration the aspects of road subgrade,semi-rigid base and asphalt layer.

数字人工生命模型Autolife的研究与改进

人工生命是一门正在发展的新兴学科,研究了数字人工生命模型Autolife的生命特征,在此基础上,通过增加角色、完善各种角色之间的生存规则,更真实地模拟了自然生存环境和生命特点,为计算机游戏、虚拟现实等计算机动画的应用领域提供了模型参考。

Treatment of malignant digestive tract obstruction by combined intraluminal stent installation and intra-arterial drug infusion

AIM: To study the palliative treatment of malignant obstruction of digestive tract with placement of intraluminal stent combined with intra-arterial infusion of chemotherapeutic drugs. METHODS: A total of 281 cases of digestive tract malignant obstruction were given per oral (esophagus, stomach, duodenum and jejunum), per anal (colon and rectum) and percutaneous transhepatic (biliary) installation of metallic stent. Among them, 203 cases received drug infusion by cannulation of tumor supplying artery with Seldinger's technique. RESULTS: Altogether 350 stents were installed in 281 cases, obstructive symptoms were relieved or ameliorated after installation. Occurrence of restenotic obstruction was 8-43 weeks among those with intra-arterial drug infusion, which was later than 4-26 weeks in the group with only stent installation. The average survival time of the former group was 43 (3-105) weeks, which was significantly longer than 13 (3-24) weeks of the latter group. CONCLUSION: Intraluminal placement of stent combined with intra-arterial infusion chemotherapy is one of the effective palliative therapies for malignant obstruction of the digestive tract with symptomatic as well as etiological treatment.

Recognition of vertical vowel graphemes of Korean characters based on combination of vowel graphemes

Korean characters consist of 2 dimensional distributed consonantal and vowel graphemes. The purpose of reducing the 2 dimensional characteristics of Korean characters to linear arrangements at early stage of character recognition is to decrease the complexity of following recognition task. By defining the identification codes for the vowel graphemes of Korean characters, the rules for combination of vowel graphemes are established, and a recognition algorithm based on the rules for combination of vowel graphemes, is therefore proposed for vertical vowel graphemes. The algorithm has been proved feasilbe through demonstrating simulations.

A New Method for Chinese Character Strokes Recognition

In this paper, the problem of stroke recognition has been studied, and the strategies and the algorithms related to the problem are proposed or developed. Based on studying some current methods for Chinese characters strokes recognition, a new method called combining trial is presented. The analysis and results of experiments showed that the method has the advantage of high degree of steadiness.

Effect of Astragalus Injection Combined with Chemotherapy on Qual ity of Life in Patients with Advanced Non-small Cell Lung Cancer

Objective: To observe the effect of Astragalus injection (AI) combined with chemotherapy on quality of life (QOF) in patients with advanced non-small cell lung caner (NSCLC). Methods: Sixty NSCLC patients were randomly divided into the treated group (n=30,treated with AI combined with chemotherapy) and the control group (n=30, treated with chemotherapy alone). Chemotherapy of MVP protocol was applied to both groups. AI was supplemented to the treated group by intravenous dripping 60 ml per day. Treatment of 21-28 days consisted one treatment cycle, and 2-3 cycles were applied. WResults: The effective rate in the treated group was 40.0% and in the control group was 36.7%, the mean remission rate in them being 5.4 month s and 3.3 months, the median survival period 11 month and 7 month and the 1-year survival rate 46.75% and 30.0%, respectively, the difference of these indexes between the two groups were all significant (P<0 05). Moreover, the clinical improving rate and QOF elevation rate in the treated group was 80.4% and 43.3%, as compared with those in the control group (50.0% and 23.3% respectively), the different was also significant (P<0 01). Conclusion: AI combined with chemotherapy can significantly improve the QOF in NSCLC patients of advanced stage.

A Brief Analysis of Robison Crusoe’s Survival Method on the Island

There are three problems in human survival:ideological problem,material problem and spiritual problem.What exactlydoes it take to solve these three problems?Robinson did solve them well in the process of survival on the desert island,and his wayof survival gave us a good reference in real life.By analyzing the ideological activities and practical actions of the protagonist in thisnovel from these three angles,we can extract some excellent qualities of Robinson,which are necessary for some impetuous groupsin real life and can enhance their consciousness of happy life.

Recognition of Characters by Adaptive Combination of Classifiers

In this paper, the visual feature space based on the long Horizontals, the long Verticals, and the radicals are given. An adaptive combination of classifiers, whose coefficients vary with the input pattern, is also proposed. Experiments show that the approach is promising for character recognition in video sequences.

心肺联合康复对冠心病介入治疗后患者血脂、心肺功能的影响

目的探讨心肺联合康复对冠心病介入治疗后患者血脂、心肺功能的影响。方法选择2022-11至2023-11秦皇岛市第一医院收治的接受介入治疗后的冠心病患者180例为研究对象,随机分为对照组(n=89)和试验组(n=91),对照组进行常规药物治疗,试验组进行心肺联合康复治疗,干预时间均为3个月。对两组患者干预前后的血脂水平、心肺功能、运动功能、生活质量和自我管理能力进行比较。结果与干预前对比,两组干预后,三酰甘油(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、用力呼气量与用力肺活量比值(FEV/FVC%)、1 s用力呼气量(FEV_(1))、左心室射血分数(LVEF)、生理功能、躯体疼痛等均有明显改善,差异有统计学意义(P<0.05),试验组比对照组各项指标(LDL-C、FEV/FVC%、PEAKVO2等)改善更明显,差异有统计学意义(P<0.05)。结论心肺联合康复可降低冠脉介入术后患者的血脂水平,增强心肺功能及运动功能,提高生活质量。

基于治未病理论灸药同治对实体恶性肿瘤化疗患者骨髓抑制的预防作用

目的:基于治未病理论探讨灸药同治对实体恶性肿瘤化疗患者骨髓抑制的预防作用。方法:选取2019年1月至2022年1月于武汉科技大学附属武汉亚心总医院接受治疗的实体恶性肿瘤化疗患者120例作为研究对象,采用随机数字表法分为对照组和观察组,每组60例。对照组常规接受化疗,观察组化疗前连续3 d给予灸药同治(艾灸+加味八珍汤)。比较治疗前、化疗后7 d 2组患者中医证候积分、血常规[血红蛋白(Hb)、白细胞计数(WBC)、血小板计数(PLT)、中性粒细胞计数(NEUT)]、生命质量[卡诺夫斯凯计分(KPS)、中国癌症患者生命质量(QOL_(2))调查问卷],比较化疗后7 d 2组患者骨髓抑制情况[发生率、严重程度、重组人粒细胞集落刺激因子(rhG-CSF)使用情况]。结果:化疗后7 d,2组患者中医证候积分升高,但观察组低于对照组(P<0.05);Hb、WBC、PLT、NEUT、KPS评分及QOL_(2)评分降低,但观察组高于对照组(均P<0.05);观察组骨髓抑制发生率、rhG-CSF使用率低于对照组,0、Ⅰ度比例高于对照组(均P<0.05)。结论:基于治未病理论,灸药同治能够改善实体恶性肿瘤化疗患者临床症状及血常规,提高患者生命质量,减少骨髓抑制的发生。

基于赋能理论的自我管理方案在肝癌行靶向联合免疫治疗患者中的应用

目的:探讨基于赋能理论的自我管理方案在肝癌行靶向联合免疫治疗患者中临床应用效果。方法:前瞻性选取2022年4月至7月温州医科大学附属第一医院行靶向治疗联合免疫治疗肝癌患者60例作为研究对象,采用信封法分成对照组和观察组,每组30例。对照组采用常规的护理方案;观察组在其基础上实施基于赋能理论的自我管理方案干预,进行个性化赋能。比较2组患者出院后1个月的自我管理效能感以及生活质量得分情况。结果:干预后观察组自我效能感及各维度得分有明显提高,均高于对照组(P<0.05);观察组在整体生活质量、躯体功能、角色功能、认知功能、情绪功能、社会功能及疲倦、恶心呕吐、呼吸困难、失眠、腹泻、食欲丧失症状方面较对照组明显改善(P<0.05)。结论:运用赋能理论的自我管理干预方案,可以有效增强靶向联合免疫治疗肝癌患者的自我管理效能感,提高其战胜疾病的自信心和自我管理能力,能够改善患者的生活质量。