A Formulation of the Porous Medium Equation with Time-Dependent Porosity: A Priori Estimates and Regularity Results

We consider a generalized form of the porous medium equation where the porosity ϕis a function of time t: ϕ=ϕ(x,t): ∂(ϕS)∂t−∇⋅(k(S)∇S)=Q(S).In many works, the porosity ϕis either assumed to be independent of (or to depend very little of) the time variable t. In this work, we want to study the case where it does depend on t(and xas well). For this purpose, we make a change of unknown function V=ϕSin order to obtain a saturation-like (advection-diffusion) equation. A priori estimates and regularity results are established for the new equation based in part on what is known from the saturation equation, when ϕis independent of the time t. These results are then extended to the full saturation equation with time-dependent porosity ϕ=ϕ(x,t). In this analysis, we make explicitly the dependence of the various constants in the estimates on the porosity ϕby the introduced transport vector w, through the change of unknown function. Also we do not assume zero-flux boundary, but we carry the analysis for the case Q≡0.

Vulvectomy: Indications and Results in the General Surgery Department of the Ignace Deen Chu Hospital in Conakry

Introduction: The aim of this study was to report the indications and evaluate the results of vulvectomy in the general surgery department of Ignace Deen Hospital, CHU Conakry. Materials and Methods: This was a retrospective descriptive study, conducted over a period of five (05) years from January 1, 2018 to December 31, 2022, in the general surgery department of Ignace Deen Hospital, CHU Conakry. We included in our study all patient records in whom vulvectomy was performed. Results: We recorded 15 cases of vulvectomy out of 453 perineal surgeries, i.e. 3.31%, with a mean age of 43.56 years and extremes of 35 and 69 years. Vulvar cancer was the most common diagnosis (46.67%), followed by Buschke-Lowenstein (33.33%) and anal canal cancer extending to the vulva (20%). Six patients had undergone biopsy (40%). Vulvectomy with lymph node dissection was performed in only 9 patients (60%), and all surgical specimens were sent to anatomical pathology (100%). Conclusion: Vulvectomy is a surgical technique most often indicated for the treatment of vulvar cancer.

How to use the Surveillance,Epidemiology,and End Results(SEER)data:research design and methodology

In the United States(US),the Surveillance,Epidemiology,and End Results(SEER)program is the only comprehensive source of population-based information that includes stage of cancer at the time of diagnosis and patient survival data.This program aims to provide a database about cancer incidence and survival for studies of surveillance and the development of analytical and methodological tools in the cancer field.Currently,the SEER program covers approximately half of the total cancer patients in the US.A growing number of clinical studies have applied the SEER database in various aspects.However,the intrinsic features of the SEER database,such as the huge data volume and complexity of data types,have hindered its application.In this review,we provided a systematic overview of the commonly used methodologies and study designs for retrospective epidemiological research in order to illustrate the application of the SEER database.Therefore,the goal of this review is to assist researchers in the selection of appropriate methods and study designs for enhancing the robustness and reliability of clinical studies by mining the SEER database.

Diagnostic challenges from conflicting results of tests and imaging

Accurate diagnosis is the foundation of clinical care but accurate diagnosis is not easily reached in some cases.In rare instances,even a sophisticated multidisciplinary team at an academic medical center cannot reliably reach an accurate diagnosis after extensive testing and imaging,and has to wait until histological diagnosis or even autopsy results are available.The underlying reason of challenging diagnoses is mostly conflicting data from history,tests,and imaging that point to different diagnoses.In this issue of World Journal of Clinical Cases,Huffaker et al reported such a challenging case of a tricuspid mass in a patient with Li-Fraumeni syndrome.The case by Huffaker et al powerfully illustrates the occasional diagnostic challenges inherent in our current diagnostic approach and the current technology.Clinicians should realize that in rare situations,agnosticism in diagnosis is unavoidable but a treatment has to be initiated so long as the principle of primum non nocere is upheld.

Effect of Types and Orders of Electromagnetic Field Finite Element Meshes on Power Communication Harmonic Parameters Calculation Results of Tubular Hydrogenerators

In generator design field,waveform total harmonic distortion(THD)and telephone harmonic factor(THF)are parameters commonly used to measure the impact of generator no-load voltage harmonics on the power communication quality.Tubular hydrogenerators are considered the optimal generator for exploiting low-head,high-flow hydro resources,and they have seen increasingly widespread application in China's power systems recent years.However,owing to the compact and constrained internal space of such generators,their internal magnetic-field harmonics are pronounced.Therefore,accurate calculation of their THD and THF is crucial during the analysis and design stages to ensure the quality of power communication.Especially in the electromagnetic field finite element modeling analysis of such generators,the type and order of the finite element meshes may have a significant impact on the THD and THF calculation results,which warrants in-depth research.To address this,this study takes a real 34 MW large tubular hydrogenerator as an example,and establishes its electromagnetic field finite element model under no-load conditions.Two types of meshes,five mesh densities,and two mesh orders are analyzed to reveal the effect of electromagnetic field finite element mesh types and orders on the calculation results of THD and THF for such generators.

Parameter calculation and result storage for phase-field simulation in α-Mg dendrite growth of Mg-5-wt% Zn alloy

Parameter calculation and result storage, as two necessary steps in phase-field simulation play an important role in ensuring the accuracy of simulation results. A strategy of parameter calculation and result storage is presented for phase-field simulation in α-Mg dendrite growth of Mg-5-wt% Zn alloy under isothermal solidification. Based on the phase diagram and empirical formulas, key parameters of the phase-field model, such as equilibrium partition coefficient k, liquidus slope m, solutal diffusion coefficient in liquid Dl, and solutal diffusion coefficient in solid Ds, can be obtained.Both structured grid method and structured point method can be used to store simulation results, but using the latter method will reduce about 60% storage space and 37.5% storage time compared with the former. Finally, convergent simulation results of α-Mg dendrite growth are obtained and they are in good agreement with the experimental results about optical micrograph, which verify the accuracy of parameters and stability of storage method.

P&T-Inf: A Result Inference Method for Context-Sensitive Tasks in Crowdsourcing

Context-Sensitive Task(CST)is a complex task type in crowdsourc-ing,such as handwriting recognition,route plan,and audio transcription.The current result inference algorithms can perform well in simple crowd-sourcing tasks,but cannot obtain high-quality inference results for CSTs.The conventional method to solve CSTs is to divide a CST into multiple independent simple subtasks for crowdsourcing,but this method ignores the context correlation among subtasks and reduces the quality of result inference.To solve this problem,we propose a result inference algorithm based on the Partially ordered set and Tree augmented naive Bayes Infer(P&T-Inf)for CSTs.Firstly,we screen the candidate results of context-sensitive tasks based on the partially ordered set.If there are parallel candidate sets,the conditional mutual information among subtasks containing context infor-mation in external knowledge(such as Google n-gram corpus,American Contemporary English corpus,etc.)will be calculated.Combined with the tree augmented naive(TAN)Bayes model,the maximum weighted spanning tree is used to model the dependencies among subtasks in each CST.We collect two crowdsourcing datasets of handwriting recognition tasks and audio transcription tasks from the real crowdsourcing platform.The experimental results show that our approach improves the quality of result inference in CSTs and reduces the time cost compared with the latest methods.

Analysis of Toxicological Test Results of 580 Detergents

To evaluate the safety of detergents,the toxicological test results of 580 collected detergents were analyzed.The results showed that,in the acute oral toxicity test,94.4%and 5.6%of the samples were classified as non-toxic and toxic respectively.In skin irritation test,95.1%of the samples were mild irritation or below,and 4.9%were moderate irritation or above.In the vaginal mucosa irritation test,79.0%of the samples were very mild irritation or below,while 21.0%were mild irritation or above.In the acute inhalation toxicity test,the proportion of the samples classified as actually non-toxic and toxic were 87.9%and 12.1%respectively.In the eye irritation test,95.7%of the samples belonged to mild irritation or below,and 4.3%of the samples belonged to moderate irritation or above.The products at risk in category A,B and C products account for 6.3%,7.7%and 14.2%respectively.Of the 580 tested samples,90.9%were relatively safe,while 9.1%were at risk.These data showed that most of the tested samples meet the safety requirements for use.

Management Results and Financial Status of Rural Collective Economy under the Background of Rural Revitalization

Based on the analysis of financial statements,the performance and problems of rural collective economic organizations in their business activities were analyzed.It is believed that rural collective economy was developing continuously in a good way,with strong debt paying ability,but the operation ability and management efficiency need to be further improved.The operation was too conservative,and the asset utilization efficiency and profitability were weak.There were many unnecessary liabilities,and they developed mainly relying on their own accumulation.Therefore,it is proposed to crack the"talent dilemma"of rural collective economic operation and management,straighten out and clarify the relationship between rural collective economic organizations and villagers self-governing organizations,correctly handle the relationship between collective accumulation and member distribution,adhere to the financial input of blood replenishment and transfusion,and make liabilities reasonable according to the management development.

Vertebroplasty and Kyphoplasty: Indications and Results, a Preliminary Senegalese Experience from the Neurosurgery Department of the CHNU of Fann

Introduction: Vertebroplasty and kyphoplasty are percutaneous techniques that consist in injecting an acrylic cement into the body of a pathological vertebra. This work aims to report the experience the of Fann’s neurosurgery department in treating certain spinal pathologies by vertebroplasty and kyphoplasty. Methods: During a 3-year period from July 1, 2019 to July 31, 2022, we conducted a retrospective, descriptive and analytical study, including patients who underwent vertebroplasty or kyphoplasty for dorsolumbar spinal pathology. Results: The mean age of the 13 patients in our study was 51.61 years. Female gender was predominant in 62% (n = 8). The context of spontaneous onset was found in six patients. Nine patients had a VAS (visual analogue scale) ≥ 8 (69.23%). On clinical examination, all patients had a syndrome without neurological deficits. 84.61% of patients had a CT scan (n = 11). The dorsolumbar hinge was most affected with 53.85% of cases. Seven patients had a vertebral compression of between 25% and. The average degree of kyphosis was 8˚ and seven patients had a degree of kyphosis ≥ 10˚. Tumour aetiology accounted for 46.15% of cases. Kyphoplasty was performed in 61.53% (n = 9) of the cases and vertebroplasty was performed in 38.47% (n = 4) of the patients. Kyphoplasty was associated with biopsy in two cases and with osteosynthesis in one patient. Vertebroplasty was always associated with a biopsy. The evolution was favourable with a significant reduction in pain and vertebral kyphosis. The mean VAS decreased from 8.15 to 0.69 three months after treatment and the mean kyphosis decreased from 8˚ to 2˚. Conclusion: Kyphoplasty and vertebroplasty as percutaneous techniques allow consolidation of the vertebral body and pain relief. Kyphoplasty alone not only reduces pain but also restores the height of the compacted vertebral body.

生物胶改良黏土抗崩解特性试验研究

为研究生物胶对黏土抗崩解性的影响,采用黄原胶、瓜尔胶及黄原胶与瓜尔胶质量比为1∶1混合的复合胶对黏土进行改良,通过抗崩解试验,探究生物胶的含量和种类、压实度对改良黏土抗崩解特性的影响规律,并结合扫描电镜试验进一步分析了生物胶的改良机理。结果表明:生物胶通过增强土体颗粒之间黏聚力增强改良黏土的抗崩解特性,其崩解破坏过程可分为稳定前崩解阶段、稳定崩解阶段及稳定后崩解阶段;随着生物胶含量的增大,改良黏土稳定前崩解阶段延长,崩解速率减缓,崩解率降低;复合胶改良黏土抗崩解特性在质量分数大于1.0%后强于单一生物胶;随着压实度的提升,试样抗崩解特性明显改善。

不同机械压实条件下黑土性质及入渗特征变化研究

为探究不同机械压实条件对黑土土壤性质入渗特征的影响,以克山县典型黑土为研究对象,设置3种不同型号机械(华夏HX2104-C:154 kW、约翰迪尔554:40 kW、中国海山:19 kW)和不同压实次数(0,1,3,5,7,9次)对秋收后大豆耕地垄沟开展模拟压实,通过测定土壤容重、含水率、孔隙及土壤入渗特征,分析不同机械压实条件对土壤物理性质及土壤入渗特征的影响。结果表明:在0~10 cm土层,大型、中型、小型机械压实后土壤容重分别增加54.17%、56.25%、46.88%;总孔隙度分别减小31.58%、28.07%、29.82%;含水率分别下降19.35%、16.13%、9.68%。首次压实对土壤性质的影响最显著,容重均增加32.29%以上,土壤总孔隙度均减小15.8%以上,只有大型机械使土壤含水率显著减小9.6%。随压实次数增加,各机械压实后10~20 cm土层土壤容重从1.25 g·cm^(-3)增加至1.58 g·cm^(-3),总孔隙度从52.16%减小至38.22%,土壤含水率从27.33%下降至20.67%,其中,大型机械在首次压实使容重及孔隙特征产生显著影响,而中型及小型机械对土壤物理性质的影响主要依靠压实次数的增加对土壤起到压实的累积作用。首次压实,中型及小型机械使2 h累计入渗量分别减少87.16%、50.81%,初渗速率分别减少87.59%、70.93%,中型机械使稳渗速率显著减少92.90%;3次压实,大型机械使2 h累计入渗量、初渗速率分别显著减小73.29%、75.67%,大型及小型机械使稳渗速率分别显著减少74.07%、66.97%;至5次压实后土壤各入渗特征无显著差异。0~20 cm土层土壤容重及土壤孔隙特征均影响机械压实土壤入渗特征,其中,0~10 cm土层土壤容重是影响综合土壤入渗特征的主导因素。

Results and Application of Soil and Water Conservation Monitoring in the Yellow River Basin

Since water and soil conservation monitoring in the Yellow River Basin entered a new stage at the end of the 20th century,the monitoring scope has been expanding,the monitoring accuracy has been improving,the monitoring content and indicators have been increasing,and the monitoring technology and methods have been improving.This paper mainly analyzes the status of soil and water conservation monitoring in the Yellow River Basin,as well as the construction of the monitoring system and related research,in order to provide a reference for watershed management and development and the scientific research of water and soil conservation.

成果导向下“精益”教学资源库建设模式的构建与实践

针对高职专业教学资源库建设中资源与岗位对接度不够、资源利用率不高、学习达成度评价体系不全等问题,提出了一种成果导向下的“精益”建设模式。“精益”建设模式以成果为导向,反向设计资源模块,项目式串联建设可复用颗粒化资源,精准化设置学习目标达成评价体系,教师可以基于学情数据,利用资源库资源搭建在线课程,满足不同学习者的学习需求,实现分层次差异化教学。实践表明该模式能有效服务于专业人才培养需求,高效益建设资源库资源,提高学生学习达成度,更好的服务于教师的教学需求,为职业教育资源库提供了一种参考模式。

融入区块链的课程目标达成评价系统建构与应用研究

推进课程评价数字化转型升级,是实现教育现代化、推进教育高质量发展、建设教育强国的重要举措。然而,当前课程目标达成评价领域存在中心化管理、数据孤岛、安全性不足等问题,影响了课程目标达成评价的科学性和公信力,进而制约了课程评价数字化转型。为此,文章提出一种基于区块链技术变革课程评价的新思路,设计了融入区块链的课程目标达成评价系统,从数据共享框架、课程目标达成评价合约、隐私保护方案三个层面探讨系统的运行机制,并阐述该系统的主要功能和应用成效。文章设计的系统,可为消除数据孤岛、提高评价数据安全性、推动课程评价数字化转型提供参考。

考虑侧向刚柔边界约束的黄土填方路基沉降计算方法

提出一种新的考虑刚柔边界约束和侧向变形的黄土填方路基沉降计算方法。基于自主研发的三向加载设备和室内压缩试验,分析不同竖向加载方式和不同侧向约束对土体竖向及侧向变形的影响,提出考虑土体压实度和围压的边界影响系数,建立压实黄土侧向应变模型,给出考虑刚柔边界条件和侧向变形的黄土路基沉降计算方法。研究结果表明:边界影响系数与路基压实度和围压都呈正相关,且刚柔约束边界对黄土压缩性指标的影响程度最高能达到40%。提出的竖向和三向边界影响系数综合考虑了路基压实度、侧向围压以及边界条件的影响。利用工程实例验证了新模型计算方法的准确性和实用性,提高了传统分层总和法的精度。

路基智能压实评价指标研究进展综述

系统总结了智能压实评价指标(ICMV)迄今为止的主要研究成果,讨论了ICMV的发展历程、计算原理、优势与缺陷、填料适用性以及与原位指标拟合的影响因素。分析表明:ICMV与路基填料之间存在一定的匹配机制,工程上应尽量按照该机制选择ICMV以提升检测效果;拟合分析时,应综合考虑填料类型、ICMV类型和原位指标以确定影响因素,避免回归特征的冗余或缺失;鉴于部分特征对预测值存在非线性影响,不建议使用线性模型对智能压实数据进行预测。针对上述问题,本文在ICMV与填料的匹配关系、拟合因素的重要性、回归算法的选择策略三个方面给出了具体的建议及未来的研究方向,以期作为ICMV后续应用及研究的参考。

单组分湿固化型聚氨酯混合料的体积膨胀特性

为研究单组分湿固化型聚氨酯混合料的体积膨胀特性,提出了基于游标卡尺的体积膨胀特性表征方法,分析了体积膨胀后的宏微观形貌,研究了不同因素作用下体积膨胀的变化规律,以及体积膨胀对空隙率的影响,并提出了抑制体积膨胀的方法.结果表明:聚氨酯混合料会因空隙率较小,致使固化反应产生的二氧化碳气体难以完全逸出,在混合料内部会产生数量较多的宏微观气孔结构,1个马歇尔试样可产生高达1.5 mm的膨胀变形;提高压实温度、采用二次压实或添加氢氧化钙,均会显著降低混合料的体积膨胀,且对路用性能也有一定提升;增大胶石比,混合料的体积膨胀单调递增,空隙率则先减小后增大.为控制体积膨胀,建议压实温度为45~65℃,且胶石比不宜过大,添加氢氧化钙时,其质量分数不宜超过1%.

公路土质路基振动压实特性数值模拟

采用ABAQUS有限元软件模拟压路机振动压实过程,研究不同碾压方式、碾压组合、松铺厚度D和压路机碾压速度V下路基土的动力响应与压实度变化规律。结果表明:不同碾压方式下最大竖向应力(S_(33))_(max)和竖向位移(U_(3))_(max)大小顺序为强振>弱振>静压,(S_(33))_(max)随碾压遍数N增加保持不变,而(U_(3))_(max)和压实度K在N=1时急剧增加;碾压组合对不同碾压方式下路基土体积应力p影响极小,碾压组合中碾压方式排列次序对路基土竖向位移U_(3)变化影响较大;组合1下不同松铺厚度的路基土竖向位移百分比P、压实度K值均大于碾压组合2,不同组合下D=40 cm时P、K值均为最大;在确定的松铺厚度下,碾压组合与碾压速度对P、K具有显著影响,碾压速度较小时P、K更大,但组合1条件下P、K关于碾压速度的差异较组合2显著。

汽车类专业人才产教融合+OBE理念培养实践——以《汽车电气设备》为例

基于“以学生发展为中心”的教育理念和落实“立德树人”的根本任务,针对《汽车电气设备》课程存在的教学手段单一、思政资源挖掘不深、教学评价体系不完善等教学痛点问题,结合课程特点,从“课程目标确定、教学资源创建、教学内容重塑、教学手段与模式改革、教学评价体系设计”5个方面系统性地实施了教学改革与实践,取得了一系列成效。学生学业成绩、高阶汽车电路分析与设计能力、综合素养不断提升;课程教学成果丰硕。