Community-Based Hepatitis B Campaign in Asian Americans

Chronic hepatitis B (CHB) disproportionately affects minority groups in the US, particularly Asian Americans, with numerous factors contributing to this disparity. Of the 2.4 million people living with chronic HBV in the US, 60% are Asian American. Many are unaware of their status and lack access to proper clinical care, with less than ten percent receiving necessary antiviral treatment. Barriers to screening and care include lack of disease awareness, language and cultural barriers, and financial constraints. Additionally, healthcare providers and systems in the US often overlook the importance of CHB, leading to inadequate care. In response, the Center for Viral Hepatitis (CVH) has implemented a community-based outreach program over the past sixteen years, employing a multifaceted approach involving all sectors of society and various organizations to combat health disparities in CHB. This grassroots campaign has proven highly effective, leveraging CVH’s leadership in spearheading numerous collaborative activities with community members, healthcare professionals, and policymakers. We have summarized the key points of CVH's efforts and their significance in combating CHB-related health disparities. The CHB Screening and Awareness Campaign, tailored to the Asian American community, serves as a successful model for increasing CHB screening, linkage-to-care, and addressing socio-cultural barriers and health literacy. Insights from these outreach programs have guided the development of culturally relevant resources and education initiatives. These findings suggest that such community-driven approaches are essential for addressing health disparities. The strategies and outcomes of CVH’s efforts can inform future health initiatives for other minority communities in the US and globally.

Competency-based curriculum education in mental health nursing

Introduction: The essential problems in providing quality and safety services to patients, rapid changes in health care settings as well as information technology require educational revision. Competency-based curriculum focuses on set of skills that students should achieve. This study reviewed characteristics of competency-based curriculum in psychiatric nursing. Methods: A literature review about a competency-based curriculum in psychiatric mental health nursing was carried out by searching databases including Iran Medex, Iran Doc, and Pub Med with key words such as competency-based education, competency-based curriculum, and competency-based curriculum in psychiatric mental health nursing. No time limitation was considered. Results: Results revealed that over 30 literatures have been done about nursing curriculum, but just several studies were done regarding competency-based curriculum and just a few about competency-based curriculum in psychiatric mental health nursing. Conclusion: Competency-based curriculum development is one of the essential steps to facilitate teaching-learning process. The revision of curriculum may decrease theory-practice gap and pave the way for graduates to have essential competences for their roles.

An Empirical Analysis of the Effect of Text-Based Computer-Mediated Communication on Communicative Competence

It has been suggested that text-based computer-mediated communication can help learners to use target language both in classrooms and in social contexts.It’s necessary to investigate the effect of text-based CMC on learners’communicative competence by conducting the method of systematic review.The findings implied that text-based CMC settings allowed learners to interact.The interaction provided learners with more opportunities to develop their communicative competence of target language.

The Effect of Simulation-Based Training on Nursing Students’ Communication Skill, Self-Efficacy and Clinical Competence for Nursing Practice

Background: Simulation-based training is a new strategy in teaching that gives the students good opportunities to learn and apply what they learn in nursing care safely. Aim: This study conducted to evaluate the effects of simulation-based training on nursing students’ communication skill, self-efficacy and clinical competence in practice. Subjects and Methods: Quiz-experimental design was used in this study (pre-posttest intervention), it was carried out on 100 nursing students first semester in 2019 using low and high-fidelity simulators. This study was carried out at College of Applied Medical Sciences-Bshia University. Data Collection: demographic data, communication skill, self-efficacy and clinical competence questionnaires. Analysis is done by SPSS version 20 software. Results: Participants who received the simulation-based training, showed statistical significant improvement in communication skill, self-efficacy, and clinical competence scores after participation in the simulation program (t = −32.64, p = 0.001;t = −19.9, p = 0.001;16.4, p = 0.001). Also, there are significant relation between gender and clinical competency (t = 2.768, p Conclusion: Simulation-based training in medical courses is effective in enhancing communication skill, self-efficacy and clinical competence. Multiple-patient simulations as a teaching-learning strategy in the nursing curriculum are highly recommended.

On Effectiveness of Task-based Reading Teaching in Vocational College

Task-based Language Teaching advocates that the students' learning is to master the language naturally and automatically by finishing real tasks in activities,which is a communicative process.Based upon Willis' model for TBLT,the author has done experiment in two classes.The results showed that task-based reading teaching is suitable to vocational college students.There is great significance appeared in the learning quality on the students in experimental class.(1) It can build up the students' self-confidence in reading.(2) It can facilitate the students' reading comprehension.(3) It helps to cultivate the students' autonomous reading habit.

胜任力导向的Mini-CEX和DOPS在骨科住院医师规范化培训中的应用研究

目的评估应用胜任力导向的迷你临床演练评估(mini-clinical evaluation exercise,Mini-CEX)和操作技能直接观察评估(direct observation of procedural skills,DOPS)在骨科住院医师规范化培训中岗位胜任力提高的效果。方法将2020年8月至2023年7月在华中科技大学同济医学院附属协和医院骨科住培基地进行住院医师规范化培训的46名住院医师,随机分为试验组和对照组,每组23例。两组教学方法相同,试验组采用胜任力导向的Mini-CEX和DOPS形成性评价和终结性评价方法,对照组单纯采用终结性评价方法。通过年度理论考核,包括基础理论考试及临床技能操作,比较两组住院医师的临床综合能力;通过Mini-CEX和DOPS评估比较试验组培训前后的评分。结果试验组住院医师在年度考核中的技能考核成绩和总成绩均高于对照组(P<0.05),两组的理论考核成绩无显著性差异(P>0.05)。试验组培训后Mini-CEX考核在医疗面谈、体格检查、人文素养、临床判断、沟通技能、组织效能、整体表现7项核心能力评分上均有显著改善(P<0.05)。试验组培训后DOPS考核在人文素养、相关知识、准备工作、病人安全、技术能力、无菌观念、后期管理7项核心能力评分上均有显著改善(P<0.05)。结论胜任力导向的Mini-CEX和DOPS的形成性评价有助于提高骨科住院医师的临床综合能力及岗位胜任力。

A 330-500 GHz Zero-Biased Broadband Tripler Based on Terahertz Monolithic Integrated Circuits

A 330-500 GHz zero-biased broadband monolithic integrated tripler is reported. The measured results show that the maximum efficiency and the maximum output power are 2% and 194μW at 348 GHz. The saturation characteristic test shows that the output i dB compression point is about -8.5 dBm at 334 GHz and the maximum efficiency is obtained at the point, which is slightly below the 1 dB compression point. Compared with the conventional hybrid integrated circuit, a major advantage of the monolithic integrated circuit is the significant improvement of reliability and consistency. In this work, a terahertz monolithic frequency multiplier at this band is designed and fabricated.

Application of Task-based Teaching Approach to Business Oral English Teaching

Task-based teaching approach(TBTA) is widely accepted and plays a more important role in foreign language teach ing.This paper is aimed at analyzing specific task design and the application of task-based teaching approach to business oral Eng lish teaching.It briefly introduces what the task-based teaching approach is and Willis'model for TBTA.Based on this model,it probes deeply into the teaching tasks design and teaching procedures.By applying the task-based teaching approach in business oral English teaching,teachers can assign students various tasks in the class to not only arose students'interest in English but also develop their communicative competence of business English.

社区-家庭合作型护理模式在产褥期母婴居家护理管理中的应用

目的:探讨社区-家庭合作型护理模式在产褥期母婴居家护理管理中的应用。方法:选取本地2个社区的产褥期产妇为研究对象。按照分娩的时间顺序分为对照组和干预组,2022年1月1日—6月30日纳入的研究对象为对照组(n=43),2022年7月1日—12月31日纳入的研究对象为干预组(n=47)。对照组对产褥期产妇和新生儿进行常规的3次社区家庭访视,干预组在常规家庭访视的基础上,实施社区-家庭合作型护理模式的母婴居家护理。比较两组爱丁堡产后抑郁量表和中文版育儿胜任感量表得分情况。结果:干预后,干预组产妇爱丁堡产后抑郁量表得分低于对照组,差异有统计学意义(P<0.05);中文版育儿胜任感量表总分和各维度得分均高于对照组,差异均有统计学意义(P<0.05)。结论:社区-家庭合作型护理模式能提高产妇的育儿胜任感,缓解产妇产后抑郁情绪,降低产后抑郁率。

Benchmarks： An Evidence-based Approach to Creating High Performing Nurses

Consensus is evident among influential professional organizations （American Nurses Association, American College of Nurses, Institute of Medicine, National Council of State Boards of Nursing, World Health Organization, National Institute of Health, Quality Safety and Education for Nursing and the American Association of Critical Care Nurses） as to essential core competencies for healthcare providers. Although there is agreement among them, assessment and measurement of competence for RN＇s in transition is overly complex. Eleven benchmarks were developed as foundational criteria to determine readiness to practice through research of national healthcare organizations position statements on competency and subsequently cross walked with identified core competeneies. This article introduces the concept of evidence-based benchmarks as a mechanism to determine readiness to practice safely, competently and independently among novice and experienced nurses who are in transition.

SELECTING CLUSTER MODEL IN Sn - BASED SOLDER ALLOY DESIGN WITH DV - X_α CALCULATION METHOD

Applying calculation method in alloy design should be an important tendency due to its characters of inexpensive cost, high efficiency and prediction. DOS calculations of AuSn, AsSn and SbSn Sn- based alloys have been investigated by employing DV - Xa method, in which different cluster models were adopted to calculate electron structure.It is proved that some regulations must be taken into ac- count in order to carry out alloy design calculation successfully,which are described in this paper in detail.

Preparation and the Pore Structure of Viscose-based Activated Carbon Fibers Treated with Pretreatment Reagents

The viscose rayon was pretreated with four different pre-treatment reagents respectively, and the preparation ofactivated carbon fibers (ACF) was performed undersame carbonizing and activating conditions. The poresize distribution, the specific surface area, and the porestructure parameter of these viscose - based ACF werestudied by using quartz spring balance BET- weightmethod. The experiment result indicates that the poresize distribution and the pore structure parameter ofACF is varied by using different pretreatment reagents.

GRAPHICAL COMPUTING METHOD ON FOUR-BAR LINKAGE(1)——Inflexion Circle,Focal Axis,Ball's Point,Centering-point Curve and Circling-point Curve For Four ISPs,Coupler Curves Based on Ball's Points——

By means of programs GTMPAC based- on generalized triangle method,analysis and synthesis of mechanism design in accordance with absolutely graphicalmethod( absolutely germetrical method) are developed.In this paper,we make aspecial study about centering- point curve and circling- point curve and couplercurves based on Ball’s points.

Item-Level Analysis of the Revised Occupational Therapy Fieldwork Performance Evaluation Applied in Practice

Competency-based assessments for healthcare professionals are critical for safe and effective client outcomes. Rehabilitation clinical skill competency assessments must be validated and revised to produce safe and skilled practitioners. The revised American Occupational Therapy Association (AOTA) Fieldwork Performance Evaluation (FWPE) instrument measures occupational therapy student performance to determine readiness for practice. The assessment includes thirty-seven competencies that address both profession specific clinical skills and general professional behavior skills. The objective of this study was to use Rasch methods to explore the use of the revised FWPE in actual fieldwork practice and to determine the instrument’s psychometric properties when separating the item components into two distinct subdomains: General Health Professions Competences and Occupational Therapy-Specific Competencies. Internal construct validity and test reliability were analyzed using data from 149 occupational therapy students after completing their initial Level II A fieldwork clinical internship. This study examined the item difficulty hierarchy, item fit, person-fit to model, person separation index, person separation reliability coefficient, strata, ceiling and floor effect, and unidimensionality of the FWPE instrument as a whole and as two separate domains. With the exception of not meeting the criteria for unidimensionality, the full FWPE instrument and the Occupational Therapy-Specific Competencies subdomain showed acceptable item-level psychometrics for reliability and precision. While the General Health Professions Competencies subdomain showed good item-level psychometrics, it was below the criterion for reliability and only separated the sample into two strata. Results support the validity, reliability, and clinical use of the revised FWPE full instrument and the Occupational Therapy-Specific Competencies subdomain to measure entry-level clinical skill competencies in practice.

On the Application of Task-Based Approach to Junior Middle School English Reading Teaching

In order to alter the reality of reading teaching, arouse students' reading interest and to improve their reading competence, the author conducted an empirical research on the application of Task-Based Approach to junior middle school English reading teaching. The research aims to encourage students to take an active part in class, stimulate their reading interest, and to improve their reading competence by students' complement of reading tasks; furthermore, it probes into the difficulties about the application of Task-Based Approach to practical teaching so that it can provide reference for teachers' improvement of teaching methods.

基于“学生中心-能力导向”的《安全评价》课程教学改革

该文基于“学生中心-能力导向”的教学理念,对《安全评价》课程进行教学改革。将课程内容优化为“知识模块-知识单元-知识点”模式,并设置训练主题提升学生相应的各项能力。改变传统重教轻学的教学方式,充分利用自学、讨论课等形式培养学生自主学习和解决复杂安全工程问题的能力。

Long noncoding RNA RP4 functions as a competing endogenous RNA through miR-7-5p sponge activity in colorectal cancer

AIM To investigate the role of long noncoding RNA(lnc RNA) RP4 in colorectal cancer.METHODS Lentivirus-mediated lnc RNA RP4 overexpression and knockdown were performed in the colorectal cancer cell line SW480. Cell proliferation, tumor growth, and early apoptosis were evaluated by a cell counting kit-8 assay, an in vivo xenograft tumor model, and annexin V/propidium iodide staining, respectively. Analysis of the lnc RNA RP4 mechanism involved assessment of the association of its expression with mi R-7-5 p and the SH3 GLB1 gene. Western blot analysis was also performed to assess the effect of lnc RNA RP4 on the autophagy-mediated cell death pathway and phosphatidylinositol-3-kinase(PI3 K)/Akt signaling.RESULTS Cell proliferation, tumor growth, and early apoptosis in SW480 cells were negatively regulated by lnc RNA RP4. Functional experiments indicated that lnc RNA RP4 directly upregulated SH3 GLB1 expression by acting as a competing endogenous RNA(ce RNA) for mi R-7-5 p. This interaction led to activation of the autophagy-mediated cell death pathway and de-repression of PI3 K and Akt phosphorylation in colorectal cancer cells in vivo.CONCLUSION Our results demonstrated that lnc RNA RP4 is a ce RNA that plays an important role in the pathogenesis of colorectal cancer, and could be a potential therapeutic target for colorectal cancer treatment.

基于胜任力导向的Mini-CEX及DOPS形成性评价体系在妇产科住院医师培养中的应用

目的:评估联合应用Mini-CEX和DOPS在妇产科住院医师规范化培训中的效果。方法:在住院医师规范化培训过程中分别运用基于Mini-CEX和DOPS的形成性评价体系、基于常规出科笔试的结论性评价体系对妇产科住院医师临床能力测评共40人次,分别运用LCSAS、年度考核通过率及优秀率对培训前后住院医师医患沟通技能和临床综合能力进行评价。结果:Mini-CEX和DOPS联合应用可显著提升学员医患沟通技巧和临床综合能力。结论:Mini-CEX和DOPS联合应用在妇产科住培教学优于传统评价体系,可显著提升住院医师岗位胜任力。

项目化学习能有效提升学业成绩吗--基于44项实验和准实验研究结果的元分析

随着全球范围内对学生核心素养、关键能力等越来越重视,项目化学习已成为各地推进课堂教学改革的重要抓手。然而,尽管项目化学习一直被冠以“有效”之名,但似乎少有研究系统评估过它对学业成绩的促进作用。采用元分析的方法对国内外44项课堂实验和准实验研究的结果进行分析,结果发现:项目化学习对学业成绩的提升作用整体处于中等水平(g=0.580),值得进一步推广和探索;不同学科、学段开展项目化学习的效果差异不明显,都能取得一定成效;项目化学习在亚非拉等地区发展中国家的开展效果较好,成绩提升作用明显;围绕某个单元或内容主题展开的项目化学习最能提升学生学业成绩,而长期教学改革实验效果最差,几乎没有任何促进作用。由此,建议我国根据地区实际的教育水平和现状合理开展项目化学习,尤其注意精选学校、精简项目,从个别主题、短期项目出发,循序渐进,这样可能会取得最大效益。

The circ_0002538/miR-138-5p/plasmolipin axis regulates Schwann cell migration and myelination in diabetic peripheral neuropathy

Circular RNAs(circRNAs)play a vital role in diabetic peripheral neuropathy.However,their expression and function in Schwann cells in individuals with diabetic peripheral neuropathy remain poorly understood.Here,we performed protein profiling and circRNA sequencing of sural nerves in patients with diabetic peripheral neuropathy and controls.Protein profiling revealed 265 differentially expressed proteins in the diabetic peripheral neuropathy group.Gene Ontology indicated that differentially expressed proteins were mainly enriched in myelination and mitochondrial oxidative phosphorylation.A real-time polymerase chain reaction assay performed to validate the circRNA sequencing results yielded 11 differentially expressed circRNAs.circ_0002538 was markedly downregulated in patients with diabetic peripheral neuropathy.Further in vitro experiments showed that overexpression of circ_0002538 promoted the migration of Schwann cells by upregulating plasmolipin(PLLP)expression.Moreover,overexpression of circ_0002538 in the sciatic nerve in a streptozotocin-induced mouse model of diabetic peripheral neuropathy alleviated demyelination and improved sciatic nerve function.The results of a mechanistic experiment showed that circ_0002538 promotes PLLP expression by sponging miR-138-5p,while a lack of circ_0002538 led to a PLLP deficiency that further suppressed Schwann cell migration.These findings suggest that the circ_0002538/miR-138-5p/PLLP axis can promote the migration of Schwann cells in diabetic peripheral neuropathy patients,improving myelin sheath structure and nerve function.Thus,this axis is a potential target for therapeutic treatment of diabetic peripheral neuropathy.