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Applying the Shearlet-Based Complexity Measure for Analyzing Mass Transfer in Continuous-Flow Microchannels
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作者 Elena Mosheva Ivan Krasnyakov 《Fluid Dynamics & Materials Processing》 EI 2024年第8期1743-1758,共16页
Continuous-flow microchannels are widely employed for synthesizing various materials,including nanoparticles,polymers,and metal-organic frameworks(MOFs),to name a few.Microsystem technology allows precise control over... Continuous-flow microchannels are widely employed for synthesizing various materials,including nanoparticles,polymers,and metal-organic frameworks(MOFs),to name a few.Microsystem technology allows precise control over reaction parameters,resulting in purer,more uniform,and structurally stable products due to more effective mass transfer manipulation.However,continuous-flow synthesis processes may be accompanied by the emergence of spatial convective structures initiating convective flows.On the one hand,convection can accelerate reactions by intensifying mass transfer.On the other hand,it may lead to non-uniformity in the final product or defects,especially in MOF microcrystal synthesis.The ability to distinguish regions of convective and diffusive mass transfer may be the key to performing higher-quality reactions and obtaining purer products.In this study,we investigate,for the first time,the possibility of using the information complexity measure as a criterion for assessing the intensity of mass transfer in microchannels,considering both spatial and temporal non-uniformities of liquid’s distributions resulting from convection formation.We calculate the complexity using shearlet transform based on a local approach.In contrast to existing methods for calculating complexity,the shearlet transform based approach provides a more detailed representation of local heterogeneities.Our analysis involves experimental images illustrating the mixing process of two non-reactive liquids in a Y-type continuous-flow microchannel under conditions of double-diffusive convection formation.The obtained complexity fields characterize the mixing process and structure formation,revealing variations in mass transfer intensity along the microchannel.We compare the results with cases of liquid mixing via a pure diffusive mechanism.Upon analysis,it was revealed that the complexity measure exhibits sensitivity to variations in the type of mass transfer,establishing its feasibility as an indirect criterion for assessing mass transfer intensity.The method presented can extend beyond flow analysis,finding application in the controlling of microstructures of various materials(porosity,for instance)or surface defects in metals,optical systems and other materials that hold significant relevance in materials science and engineering. 展开更多
关键词 Shearlet analysis complexity measure entropy measure CONVECTION microchannels double-diffusive instability
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The Impact of Storyline Complexity on L2 Learners’Written Performance
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作者 CHEN Yu-lian 《Journal of Literature and Art Studies》 2024年第5期369-372,共4页
Task-based Language Teaching(TBLT)research has provided ample evidence that cognitive complexity is an important aspect of task design that influences learner’s performance in terms of fluency,accuracy,and syntactic ... Task-based Language Teaching(TBLT)research has provided ample evidence that cognitive complexity is an important aspect of task design that influences learner’s performance in terms of fluency,accuracy,and syntactic complexity.Despite the substantial number of empirical investigations into task complexity in journal articles,storyline complexity,one of the features of it,is scarcely investigated.Previous research mainly focused on the impact of storyline complexity on learners’oral performance,but the impact on learners’written performance is less investigated.Thus,this study aims at investigating the effects of narrative complexity of storyline on senior high school students’written performance,as displayed by its complexity,fluency,and accuracy.The present study has important pedagogical implications.That is,task design and assessment should make a distinction between different types of narrative tasks.For example,the task with single or dual storyline.Results on task complexity may contribute to informing the pedagogical choices made by teachers when prioritizing work with a specific linguistic dimension. 展开更多
关键词 storyline complexity narrative writing task complexity L2 writers
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Exploring Biocomplexity in Cancer: A Comprehensive Review
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作者 Andras Szasz Gyula Peter Szigeti 《Open Journal of Biophysics》 2024年第2期154-238,共85页
Living objects have complex internal and external interactions. The complexity is regulated and controlled by homeostasis, which is the balance of multiple opposing influences. The environmental effects finally guide ... Living objects have complex internal and external interactions. The complexity is regulated and controlled by homeostasis, which is the balance of multiple opposing influences. The environmental effects finally guide the self-organized structure. The living systems are open, dynamic structures performing random, stationary, stochastic, self-organizing processes. The self-organizing procedure is defined by the spatial-temporal fractal structure, which is self-similar both in space and time. The system’s complexity appears in its energetics, which tries the most efficient use of the available energies;for that, it organizes various well-connected networks. The controller of environmental relations is the Darwinian selection on a long-time scale. The energetics optimize the healthy processes tuned to the highest efficacy and minimal loss (minimalization of the entropy production). The organism is built up by morphogenetic rules and develops various networks from the genetic level to the organism. The networks have intensive crosstalk and form a balance in the Nash equilibrium, which is the homeostatic state in healthy conditions. Homeostasis may be described as a Nash equilibrium, which ensures energy distribution in a “democratic” way regarding the functions of the parts in the complete system. Cancer radically changes the network system in the organism. Cancer is a network disease. Deviation from healthy networking appears at every level, from genetic (molecular) to cells, tissues, organs, and organisms. The strong proliferation of malignant tissue is the origin of most of the life-threatening processes. The weak side of cancer development is the change of complex information networking in the system, being vulnerable to immune attacks. Cancer cells are masters of adaptation and evade immune surveillance. This hiding process can be broken by electromagnetic nonionizing radiation, for which the malignant structure has no adaptation strategy. Our objective is to review the different sides of living complexity and use the knowledge to fight against cancer. 展开更多
关键词 complexity Networks SMALL-WORLD Genetic Mutations SELF-ORGANIZING Self-Symmetry Energetic Balance Entropy Nash Equilibrium GAMES Evolution CANCER Therapy
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A Comparative Analysis of Syntactic Complexity in Applied Linguistics Abstracts Written by Chinese Novice Writers and Native English Advanced Writers
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作者 Mingming Zhao Tianshuang Ge 《Open Journal of Applied Sciences》 2024年第1期1-26,共26页
The rhetorical structure of abstracts has been a widely discussed topic, as it can greatly enhance the abstract writing skills of second-language writers. This study aims to provide guidance on the syntactic features ... The rhetorical structure of abstracts has been a widely discussed topic, as it can greatly enhance the abstract writing skills of second-language writers. This study aims to provide guidance on the syntactic features that L2 learners can employ, as well as suggest which features they should focus on in English academic writing. To achieve this, all samples were analyzed for rhetorical moves using Hyland’s five-rhetorical move model. Additionally, all sentences were evaluated for syntactic complexity, considering measures such as global, clausal and phrasal complexity. The findings reveal that expert writers exhibit a more balanced use of syntactic complexity across moves, effectively fulfilling the rhetorical objectives of abstracts. On the other hand, MA students tend to rely excessively on embedded structures and dependent clauses in an attempt to increase complexity. The implications of these findings for academic writing research, pedagogy, and assessment are thoroughly discussed. 展开更多
关键词 Syntactic complexity Rhetorical Functions Research Article Abstract L2 Academic Writing
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基于胶质细胞GR/CX3CR1双信号探讨柴金解郁安神片含药血清减轻体外抑郁模型大鼠ACC神经元突触损伤的机制
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作者 刘检 杨蕙 +2 位作者 赵洪庆 孟盼 王宇红 《中国病理生理杂志》 CAS CSCD 北大核心 2024年第6期997-1007,共11页
目的:基于胶质细胞糖皮质激素受体(glucocorticoid receptor,GR)/CX3C趋化因子受体1(CX3C chemokine receptor 1,CX3CR1)双信号探讨柴金解郁安神片(CJJY)含药血清对体外抑郁模型中大鼠前扣带皮层(anterior cingulate cortex,ACC)神经元... 目的:基于胶质细胞糖皮质激素受体(glucocorticoid receptor,GR)/CX3C趋化因子受体1(CX3C chemokine receptor 1,CX3CR1)双信号探讨柴金解郁安神片(CJJY)含药血清对体外抑郁模型中大鼠前扣带皮层(anterior cingulate cortex,ACC)神经元突触损伤的保护机制。方法:原代培养SD大鼠ACC脑区星形胶质细胞、小胶质细胞和神经元,并分别进行鉴定;采用200μmol/L皮质酮(corticosterone,CORT)联合1 mg/L脂多糖(lipopolysaccharide,LPS)建立模拟抑郁环境的体外细胞模型,实验设正常组、模型组(CORT+LPS)、GR阻断剂(GR-)组(CORT+LPS+RU486)、GR激动剂(GR+)组(CORT+LPS+dexamethasone)、CX3CR1阻断剂(CX3-)组(CORT+LPS+AZD8797)、CX3CR1激动剂(CX3+)组(CORT+LPS+fractalkine)、CJJY组(CORT+LPS+CJJY含药血清)、CJJY联合GR激动剂(CJJY/GR+)组(CORT+LPS+CJJY含药血清+dexamethasone)组和CJJY联合CX3CR1激动剂(CJJY/CX3+)组(CORT+LPS+CJJY含药血清+fractalkine);高内涵细胞成像分析技术观察星形胶质细胞、小胶质细胞和ACC神经元形态学变化;ELISA法检测细胞上清液中促肾上腺皮质激素(adrenocorticotropic hormone,ACTH)、促肾上腺皮质激素释放激素(corticotropin-releasing hormone,CRH)、CORT、肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)、白细胞介素1β(interleukin-1β,IL-1β)、IL-6和谷氨酸(glutamate,Glu)水平;免疫荧光染色检测星形胶质细胞中GR和囊泡谷氨酸转运体1(vesicular glutamate transporter 1,VGluT1)表达水平,以及小胶质细胞中CX3CR1和腺苷A2A受体(adenosine A2A receptor,A2AR)表达水平;Nissl染色和β-tubulin染色观察神经元突触损伤情况。结果:CJJY含药血清能减轻体外抑郁模型中大鼠星形胶质细胞损伤,抑制小胶质细胞激活,同时抑制细胞上清液中ACTH、CRH、CORT、TNF-α、IL-1β、IL-6和Glu水平异常增高(P<0.05或P<0.01),有效调控GR、VGluT1、CX3CR1和A2AR表达异常(P<0.05或P<0.01),并减轻大鼠ACC神经元树突和树突棘损伤。结论:CJJY含药血清通过调控胶质细胞GR/CX3CR1双信号而减轻体外抑郁模型中大鼠ACC神经元突触损伤。 展开更多
关键词 抑郁症 柴金解郁安神片 前扣带皮层 神经元 突触损伤 糖皮质激素受体 cx3C趋化因子受体1
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迈瑞CX-9000全自动凝血分析仪性能评估
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作者 郭家权 韦炅 +2 位作者 李苗 李坷坷 刘明 《医疗卫生装备》 CAS 2024年第2期58-61,共4页
目的:对迈瑞CX-9000全自动凝血分析仪的性能进行验证评估。方法:参照行业标准和国家标准,通过凝血酶原时间(prothrombin time,PT)、活化部分凝血活酶时间(activated partial thromboplastin time,APTT)、纤维蛋白原(fibrinogen,FIB)、... 目的:对迈瑞CX-9000全自动凝血分析仪的性能进行验证评估。方法:参照行业标准和国家标准,通过凝血酶原时间(prothrombin time,PT)、活化部分凝血活酶时间(activated partial thromboplastin time,APTT)、纤维蛋白原(fibrinogen,FIB)、凝血酶时间(thrombin time,TT)、D-二聚体5个凝血常规检查项目对迈瑞CX-9000全自动凝血分析仪进行性能验证,评估该仪器的精密度、准确度、线性范围、携带污染率及参考区间能否满足临床需求。结果:5个凝血常规检查项目的批内精密度变异系数(coefficient of variation,CV)均<3%,日间精密度CV均<5%,准确度相对偏差在±10%以内。FIB的线性回归方程斜率k为1.0060,相关系数r为0.9993,D-二聚体的线性回归方程k为1.0132,r为0.9975,线性良好。样本浓度携带污染率CR1为4.6%,项目携带污染率CR2均<2%,参考区间R值均为100%,均符合行业标准要求,验证通过。结论:迈瑞CX-9000全自动凝血分析仪是一款精密度好、准确度高、线性范围宽、携带污染率低的检测系统,能够满足临床需求。 展开更多
关键词 迈瑞cx-9000全自动凝血分析仪 精密度 准确度 携带污染率 线性范围 参考区间 性能评估
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创伤性膝骨关节炎患者血清CX3CL1、Apelin-13与炎症指标的相关性及预后价值 被引量:1
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作者 吕新凯 李光磊 +4 位作者 段强民 王宝鹏 张平 孙全省 张冰 《国际检验医学杂志》 CAS 2024年第9期1126-1130,共5页
目的 探索创伤性膝骨关节炎(PTOA)患者血清趋化因子CX3CL1及脂肪细胞因子-13(Apelin-13)的表达水平,并分析二者与炎症指标的相关性及预后价值。方法 选取2020年1月至2022年2月在该院确诊的65例PTOA患者作为试验组,选取同期来该院体检的5... 目的 探索创伤性膝骨关节炎(PTOA)患者血清趋化因子CX3CL1及脂肪细胞因子-13(Apelin-13)的表达水平,并分析二者与炎症指标的相关性及预后价值。方法 选取2020年1月至2022年2月在该院确诊的65例PTOA患者作为试验组,选取同期来该院体检的55例体检健康者作为对照组。通过酶联免疫吸附试验(ELISA)检测血清CX3CL1与Apelin-13的表达水平。Pearson法相关性分析血清CX3CL1与Apelin-13与炎症指标的相关性。绘制受试者工作特征(ROC)曲线分析CX3CL1与Apelin-13对PTOA患者预后的诊断价值。多因素Logistic回归分析PTOA患者预后不良的影响因素。结果 与对照组相比,试验组中白细胞介素-6(IL-6)、瘦素、降钙素原(PCT)、超敏C反应蛋白(hsCRP)、肿瘤坏死因子-α(TNF-α)、CX3CL1的表达水平显著升高,差异有统计学意义(P<0.05),Apelin-13的表达水平显著下降,差异有统计学意义(P<0.05);Pearson法相关性分析显示,CX3CL1与IL-6、瘦素、TNF-α呈正相关(r=0.528、0.602、0.511,P<0.001)。Apelin-13与IL-6呈负相关(r=-0.541,P<0.001);多因素Logistic回归分析显示IL-6、瘦素、TNF-α、CX3CL1与Apelin-13是PTOA患者预后不良的影响因素(P<0.05);ROC曲线下面积(AUC)分析显示,与血清CX3CL1和Apelin-13单独指标相比,CX3CL1联合Apelin-13预测预后不良的AUC更大(Z_(联合)-CX3CL1=2.010,P=0.044;Z_(联合)-Apelin-13=2.091,P=0.036)。结论 PTOA患者血清CX3CL1表达水平显著升高,Apelin-13表达水平显著降低,CX3CL1与Apelin-13是PTOA预后不良的影响因素,二者联合检测对于PTOA的预后提供帮助。 展开更多
关键词 创伤性膝骨关节炎 cx3CL1 脂肪细胞因子-13 预后
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母代孕期应激在损伤成年子代认知功能中对CX3CL1/CX3CR1轴的影响
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作者 柴冰茹 田晓寒 +7 位作者 吕梦姣 张馨怡 徐枭喻 张黎敏 李政 谷雨 廖礼彬 白生宾 《解放军医学院学报》 CAS 2024年第3期283-289,共7页
背景孕期应激可损害子代发育过程中中枢神经系统之间的交流,而CX3CL1/CX3CR1轴在神经元-小胶质细胞间建立了一个独特的通讯系统。目的明确孕期应激在损伤子代认知功能中是否对CX3CL1/CX3CR1轴产生影响并探究其作用机制。方法将12只SD孕... 背景孕期应激可损害子代发育过程中中枢神经系统之间的交流,而CX3CL1/CX3CR1轴在神经元-小胶质细胞间建立了一个独特的通讯系统。目的明确孕期应激在损伤子代认知功能中是否对CX3CL1/CX3CR1轴产生影响并探究其作用机制。方法将12只SD孕鼠随机分为应激组和对照组,每组6只,应激组在孕15~21 d进行限制性应激,对照组正常饲养。用旷场、高架十字迷宫、新物体识别及Y迷宫四种行为学实验评估成年子代认知功能,ELISA检测母代及子代糖皮质激素,免疫荧光染色、Western blot检测子代海马CX3CL1、CX3CR1、Iba-1表达情况。结果母代孕期应激组及子代糖皮质激素升高(P<0.05)。母代孕期应激组子代在旷场实验中,中央区滞留时间与对照组相比减少,差异有统计学意义(P<0.05);在高架十字迷宫中进入开放臂次数和滞留时间与对照组相比减少,差异有统计学意义(P<0.05),表现出焦虑样行为;在新物体识别实验中识别指数降低(P<0.05),表现出学习记忆能力下降;在Y迷宫实验中对新异臂的识别减少(P<0.05),表现出空间记忆能力下降。母代孕期应激组子代小胶质细胞激活Iba-1表达升高,CX3CR1表达升高,CX3CL1表达下降,差异均有统计学意义(P<0.05)。结论孕期应激损害成年子代认知功能可能与CX3CL1/CX3CR1通讯障碍有关。 展开更多
关键词 孕期应激 糖皮质激素 小胶质细胞 cx3CL1/cx3CR1 认知功能障碍
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Cx43、β-catenin、Smo在第二生心区的表达规律及意义
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作者 丁泽原 闫玉楠 +3 位作者 谢建山 师亮 景雅 杨艳萍 《中国组织工程研究》 CAS 北大核心 2024年第19期3042-3048,共7页
背景:第二生心区对于胚胎心脏发育具有重要意义,其发育异常会导致多种心脏畸形,Cx43基因敲除后第二生心区细胞的形成和增殖减少,但具体原因尚未明确。目的:①明确β-catenin、Smo以及Cx43在内胚层与第二生心区的表达模式,观察其有无共表... 背景:第二生心区对于胚胎心脏发育具有重要意义,其发育异常会导致多种心脏畸形,Cx43基因敲除后第二生心区细胞的形成和增殖减少,但具体原因尚未明确。目的:①明确β-catenin、Smo以及Cx43在内胚层与第二生心区的表达模式,观察其有无共表达;②探究Cx43与Wnt/β-catenin通路或Shh通路之间是否存在相互作用,共同参与第二生心区的发育。方法:选取胚龄10-12 d的ICR小鼠胚胎石蜡包埋连续切片,进行免疫组织化学染色、苏木精-伊红染色、免疫荧光染色;剥离胚龄11 d小鼠胚胎的原始消化管用于蛋白印迹实验和免疫共沉淀。结果与结论:①胚龄10-12 d,Cx43与Isl1在前肠腹侧和心包腔背侧壁的部分间充质细胞呈共表达,Isl1阳性细胞增多的同时Cx43阳性细胞也增多;②胚龄10-12 d,Cx43与β-catenin在内胚层腹侧共表达;③胚龄10-12 d,Cx43与Smo在内胚层上共表达;④免疫共沉淀结果表明Cx43与β-catenin之间存在相互作用,共同参与第二生心区的发育。 展开更多
关键词 小鼠胚胎 第二生心区 流出道 WNT/Β-CATENIN通路 Shh通路 cx43 免疫共沉淀
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CX3CL1/CX3CR1调控小胶质细胞功能的研究进展
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作者 罗维 范梦瑶 黎晓 《中国病理生理杂志》 CAS CSCD 北大核心 2024年第5期938-943,共6页
随着社会老龄化的增加,神经退行性疾病(如阿尔茨海默病、帕金森病等)和脑血管疾病(如脑出血、脑梗死等)对人类的生活产生了极大的影响。神经炎症被认为在神经退行性疾病和脑血管疾病的发生发展中起着主要作用,是一个具有潜在价值的治疗... 随着社会老龄化的增加,神经退行性疾病(如阿尔茨海默病、帕金森病等)和脑血管疾病(如脑出血、脑梗死等)对人类的生活产生了极大的影响。神经炎症被认为在神经退行性疾病和脑血管疾病的发生发展中起着主要作用,是一个具有潜在价值的治疗靶点^([1])。神经炎症在人体中具有双重作用,它本身是一种防御机制,可以去除病原体进而保护机体;然而,持续的炎症反应可诱发神经毒性与神经变性,不利于机体的恢复^([2])。小胶质细胞是大脑中释放炎症因子的主要细胞,被认为是神经炎症主要的病理特征^([3])。小胶质细胞广泛分布于大脑和脊髓,是中枢神经系统(central nervous system,CNS)中唯一具有单核巨噬细胞功能的固有免疫细胞,因而是CNS最主要的一道免疫防线^([4])。在正常生理条件下,小胶质细胞通过伸展和收缩突起连续监测周围环境和脑内稳态的改变,发挥着免疫监视的作用^([5])。 展开更多
关键词 cx3CL1/cx3CR1信号通路 小胶质细胞 活化 极化
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苹果砧木CX5组织培养体系的建立
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作者 严家帝 杨安 +2 位作者 田玉凤 韩晓蕾 张彩霞 《中国果树》 2024年第5期39-44,共6页
以苹果半矮化砧CX5的休眠枝条茎段和4月底至6月初的新生枝条茎段为试验材料,采用离体组织培养方法,研究了适宜CX5组培快繁的外植体类型、灭菌方式、灭菌时间,以及不同植物生长调节剂浓度对增殖培养的影响。结果表明:适合用作灭菌的CX5... 以苹果半矮化砧CX5的休眠枝条茎段和4月底至6月初的新生枝条茎段为试验材料,采用离体组织培养方法,研究了适宜CX5组培快繁的外植体类型、灭菌方式、灭菌时间,以及不同植物生长调节剂浓度对增殖培养的影响。结果表明:适合用作灭菌的CX5外植体类型为新生枝条茎段,其外植体褐化率和污染率都相对较低;外植体0.1%HgCl2灭菌时间控制在6min左右,伤害最小;CX5茎段腋芽诱导培养基为MS+0.75mg/L6-BA+0.3mg/LIBA,适宜组培苗增殖继代的培养基为MS+0.7mg/L6-BA+0.5mg/LIBA,生根培养基为1/2MS+0.2mg/LIAA。初步构建了CX5组培快繁技术体系。 展开更多
关键词 苹果半矮化砧 cx5 茎段 组织培养
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淫羊藿苷通过Cx32-Nox4信号通路改善高血压肾纤维化和损伤
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作者 吴笑雪 叶益平 +2 位作者 雷振东 张尊敬 陈文霖 《中国临床药理学与治疗学》 CAS CSCD 北大核心 2024年第8期870-878,共9页
目的:探讨淫羊藿苷通过Cx32-Nox4信号通路对高血压肾纤维化和损伤的影响。方法:在自发性高血压大鼠(spontaneously hypertensive rats,SHRs)上建立高血压肾病(hypertensive nephropathy,HN)大鼠模型。实验分为4组:正常对照组(WKY大鼠)... 目的:探讨淫羊藿苷通过Cx32-Nox4信号通路对高血压肾纤维化和损伤的影响。方法:在自发性高血压大鼠(spontaneously hypertensive rats,SHRs)上建立高血压肾病(hypertensive nephropathy,HN)大鼠模型。实验分为4组:正常对照组(WKY大鼠)、模型组(SHR)、淫羊藿苷10 mg·kg^(-1)·d^(-1)组(每天灌胃淫羊藿苷一次)、淫羊藿苷30 mg·kg^(-1)·d^(-1)组(每天灌胃淫羊藿苷一次),每组10只。在体内检测纤维化相关蛋白的表达。选择暴露于血管紧张素Ⅱ(AngⅡ)的NRK-52E细胞来观察淫羊藿苷对肾损伤的影响。用蛋白质免疫印迹法和免疫组化检测细胞外基质(extracellular matrix,ECM)的水平,包括α-平滑肌肌动蛋白(α-smooth muscle actin,α-SMA)、Ⅰ型胶原(collagenⅠ,Col-Ⅰ)和纤连蛋白(fibronectin,FN)的表达。试剂盒检测氧化应激标记物超氧化物歧化酶(superoxide dismutase,SOD)和丙二醛(malondialdehyde,MDA)表达的变化。结果:淫羊藿苷在体内显著降低SHR大鼠的肾脏纤维化。淫羊藿苷下调α-SMA、FN和Col-Ⅰ的表达(P<0.05),并保护高血压损伤的肾组织免受进行性纤维化的影响。淫羊藿苷可以显著提高SHR大鼠肾脏和血清中的总SOD活性,显著降低MDA水平(P<0.05)。此外,淫羊藿苷显著提高SHR大鼠肾脏中Cx32的表达,并显著减少Nox4的表达(P<0.05)。淫羊藿苷对AngⅡ介导的NRK-52E细胞损伤和纤维化具有保护作用。结论:淫羊藿苷可以改善肾小管间质纤维化并延缓HN的进展。肾脏保护可能归因于Cx32-Nox4信号通路介导的氧化应激的调节来实现。 展开更多
关键词 淫羊藿苷 cx32-Nox4信号通路 高血压肾病 肾纤维化 肾损伤
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An incommensurate fractional discrete macroeconomic system:Bifurcation,chaos,and complexity
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作者 Abderrahmane Abbes Adel Ouannas Nabil Shawagfeh 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第3期58-67,共10页
This study proposes a novel fractional discrete-time macroeconomic system with incommensurate order.The dynamical behavior of the proposed macroeconomic model is investigated analytically and numerically.In particular... This study proposes a novel fractional discrete-time macroeconomic system with incommensurate order.The dynamical behavior of the proposed macroeconomic model is investigated analytically and numerically.In particular,the zero equilibrium point stability is investigated to demonstrate that the discrete macroeconomic system exhibits chaotic behavior.Through using bifurcation diagrams,phase attractors,the maximum Lyapunov exponent and the 0–1 test,we verified that chaos exists in the new model with incommensurate fractional orders.Additionally,a complexity analysis is carried out utilizing the approximation entropy(ApEn)and C_(0)complexity to prove that chaos exists.Finally,the main findings of this study are presented using numerical simulations. 展开更多
关键词 CHAOS macroeconomic system discrete fractional calculus complexity
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Complexity of Injective Homomorphisms to Small Tournaments, and of Injective Oriented Colourings
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作者 Russell J. Campbell Nancy E. Clarke Gary MacGillivray 《Open Journal of Discrete Mathematics》 2023年第1期1-15,共15页
Several possible definitions of local injectivity for a homomorphism of an oriented graph G to an oriented graph H are considered. In each case, we determine the complexity of deciding whether there exists such a homo... Several possible definitions of local injectivity for a homomorphism of an oriented graph G to an oriented graph H are considered. In each case, we determine the complexity of deciding whether there exists such a homomorphism when G is given and H is a fixed tournament on three or fewer vertices. Each possible definition leads to a locally-injective oriented colouring problem. A dichotomy theorem is proved in each case. 展开更多
关键词 Injective Graph Homomorphism Oriented Colouring complexity
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Low Complexity Detection Algorithms Based on ADMIN for Massive MIMO
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作者 Shuchao Mi Jianyong Zhang +2 位作者 Fengju Fan Baorui Yan Muguang Wang 《China Communications》 SCIE CSCD 2023年第11期67-77,共11页
This paper proposes the alternating direction method of multipliers-based infinity-norm(ADMIN) with threshold(ADMIN-T) and with percentage(ADMIN-P) detection algorithms,which make full use of the distribution of the s... This paper proposes the alternating direction method of multipliers-based infinity-norm(ADMIN) with threshold(ADMIN-T) and with percentage(ADMIN-P) detection algorithms,which make full use of the distribution of the signal to interference plus noise ratio(SINR) for an uplink massive MIMO system.The ADMIN-T and ADMIN-P detection algorithms are improved visions of the ADMIN detection algorithm,in which an appropriate SINR threshold in the ADMIN-T detection algorithm and a certain percentage in the ADMIN-P detection algorithm are designed to reduce the overall computational complexity.The detected symbols are divided into two parts by the SINR threshold which is based on the cumulative probability density function(CDF) of SINR and a percentage,respectively.The symbols in higher SINR part are detected by MMSE.The interference of these symbols is then cancelled by successive interference cancellation(SIC).Afterwards the remaining symbols with low SINR are iteratively detected by ADMIN.The simulation results show that the ADMIIN-T and the ADMIN-P detection algorithms provide a significant performance gain compared with some recently proposed detection algorithms.In addition,the computational complexity of ADMIN-T and ADMIN-P are significantly reduced.Furthermore,in the case of same number of transceiver antennas,the proposed algorithms have a higher performance compared with the case of asymmetric transceiver antennas. 展开更多
关键词 ADMIN low complexity detection algo-rithm massive MIMO MMSE SINR
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Traffic Sign Detection with Low Complexity for Intelligent Vehicles Based on Hybrid Features
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作者 Sara Khalid Jamal Hussain Shah +2 位作者 Muhammad Sharif Muhammad Rafiq Gyu Sang Choi 《Computers, Materials & Continua》 SCIE EI 2023年第7期861-879,共19页
Globally traffic signs are used by all countries for healthier traffic flow and to protect drivers and pedestrians.Consequently,traffic signs have been of great importance for every civilized country,which makes resea... Globally traffic signs are used by all countries for healthier traffic flow and to protect drivers and pedestrians.Consequently,traffic signs have been of great importance for every civilized country,which makes researchers give more focus on the automatic detection of traffic signs.Detecting these traffic signs is challenging due to being in the dark,far away,partially occluded,and affected by the lighting or the presence of similar objects.An innovative traffic sign detection method for red and blue signs in color images is proposed to resolve these issues.This technique aimed to devise an efficient,robust and accurate approach.To attain this,initially,the approach presented a new formula,inspired by existing work,to enhance the image using red and green channels instead of blue,which segmented using a threshold calculated from the correlational property of the image.Next,a new set of features is proposed,motivated by existing features.Texture and color features are fused after getting extracted on the channel of Red,Green,and Blue(RGB),Hue,Saturation,and Value(HSV),and YCbCr color models of images.Later,the set of features is employed on different classification frameworks,from which quadratic support vector machine(SVM)outnumbered the others with an accuracy of 98.5%.The proposed method is tested on German Traffic Sign Detection Benchmark(GTSDB)images.The results are satisfactory when compared to the preceding work. 展开更多
关键词 Traffic sign detection intelligent systems complexity VEHICLES color moments texture features
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Economic complexity and environmental sustainability in eastern European economies:Evidence from novel Fourier approach
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作者 Dervis KIRIKKALELI Emrah SOFUOGLU +1 位作者 Kashif Raza ABBASI Kwaku ADDAI 《Regional Sustainability》 2023年第4期349-358,共10页
Globally,economies have become complex and new technologies have transformed and facilitated the modernization of economies.In the previous literature,economic complexity approach has become one of the popular tools i... Globally,economies have become complex and new technologies have transformed and facilitated the modernization of economies.In the previous literature,economic complexity approach has become one of the popular tools in the development and innovation studies of economic geography.Researchers have found that green technology and eco-innovation approaches should be used to decisively reduce the effects of carbon emissions on the environment.However,debates about the impact of economic complexity on environment remain unsettled since some emerging production technologies have far-reaching pollution effects.This study explored the impacts of economic complexity on environmental sustainability in Turkey using the novel Fourier-based approaches,namely:Fourier Augmented Dickey-Fuller(FADF)and Fourier Autoregressive-Distributed Lag(FARDL)models.The Fourier-based approaches indicated that all variables(economic complexity index(ECI),GDP,energy consumption,and CO_(2)emission(CO_(2)E))are cointegrated in the long run.Additionally,the FARDL model implied that(i)in the long run,the effect of ECI(as a proxy for economic complexity),GDP(as a proxy for economic growth),and energy consumption on CO_(2)E(as a proxy for environmental quality)are important;(ii)economic complexity decreases environmental degradation in Turkey;and(iii)economic growth and energy consumption negatively affect environmental quality.The results also showed that economic complexity could be used as a policy tool to tackle environmental degradation.The findings also revealed that the fossil fuelbased economy will continue to expand and undermine Turkey’s efforts to meet its net zero emission target by 2053.Therefore,policy-makers should take actions and establish diversified economic,environmental,and energy strategies.For policy insights,the Turkish governments can use the combination of tax exemptions and technical support systems to support knowledge creation and the diffusion of environmentally friendly technologies The governments can also impose strict environmental regulations on the knowledge development phases. 展开更多
关键词 Economic complexity Environmental degradation CO_(2)emission(CO_(2)E) Fourier Autoregressive-Distributed Lag(FARDL) Fourier Augmented Dickey-Fuller(FADF) Economic complexity index(ECI) Turkey
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乙型肝炎病毒相关慢加急性肝衰竭患者血清CXCL1、CXCL16与肝衰竭分期及短期预后的关系研究
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作者 彭昱锦 杨琴 +2 位作者 廖德超 严英 郎清 《疑难病杂志》 CAS 2024年第7期834-839,共6页
目的探讨乙型肝炎病毒相关慢加急性肝衰竭(HBV-ACLF)患者血清C-X-C基序趋化因子配体(CXCL)1、CXCL16与肝衰竭分期及短期预后的关系。方法选取2018年1月—2023年6月达州市中心医院肝病科收治的HBV-ACLF患者170例纳入病例组,再根据肝衰竭... 目的探讨乙型肝炎病毒相关慢加急性肝衰竭(HBV-ACLF)患者血清C-X-C基序趋化因子配体(CXCL)1、CXCL16与肝衰竭分期及短期预后的关系。方法选取2018年1月—2023年6月达州市中心医院肝病科收治的HBV-ACLF患者170例纳入病例组,再根据肝衰竭分期分为早期亚组(71例)、中期亚组(54例)、晚期亚组(45例),根据患者90 d预后分为死亡亚组(60例)和存活亚组(110例),另选取同期健康体检者100例纳入健康对照组。采用酶联免疫吸附法检测血清CXCL1、CXCL16水平;单因素及多因素Logistic回归分析HBV-ACLF患者死亡的影响因素;受试者工作特征(ROC)曲线评估血清CXCL1、CXCL16和终末期肝病模型(MELD)评分对HBV-ACLF患者死亡的预测效能。结果与健康对照组比较,病例组患者血清CXCL1、CXCL16水平显著升高(t/P=30.816/<0.001,29.811/<0.001);早期亚组、中期亚组、晚期亚组血清CXCL1、CXCL16水平依次升高(F/P=317.656/<0.001,211.391/<0.001);与存活亚组比较,死亡亚组患者血清CXCL1、CXCL16水平显著升高(t/P=7.775/<0.001,7.137/<0.001);肝衰竭分期晚期和MELD评分高、CXCL1升高、CXCL16升高为HBV-ACLF患者死亡的独立危险因素[OR(95%CI)=5.069(1.322~19.441)、1.548(1.174~2.042)、1.914(1.162~3.153)、3.423(1.468~7.980)];血清CXCL1、CXCL16联合MELD评分预测HBV-ACLF患者死亡的ROC曲线下面积为0.927,大于血清CXCL1、CXCL16和MELD评分单独预测的0.786、0.781、0.784(Z=4.594、4.261、4.288,P均<0.001)。结论HBV-ACLF患者血清CXCL1、CXCL16水平升高,与肝衰竭分期及短期不良预后有关,在MELD评分基础上联合血清CXCL1、CXCL16对HBV-ACLF患者短期预后进行预测具有较高的价值。 展开更多
关键词 乙型肝炎病毒相关慢加急性肝衰竭 C-X-C基序趋化因子配体 肝衰竭分期 预后
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CX3 chemokine receptor 1 deficiency leads to reduced dendritic complexity and delayed maturation of newborn neurons in the adult mouse hippocampus 被引量:1
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作者 Feng Xiao Jun-mei Xu Xing-hua Jiang 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第5期772-777,共6页
Previous studies have shown that microglia impact the proliferation and differentiation of neu- rons during hippocampal neurogenesis via the fractalkine/CX3 chemokine receptor i (CX3CRI) signaling pathway. However, ... Previous studies have shown that microglia impact the proliferation and differentiation of neu- rons during hippocampal neurogenesis via the fractalkine/CX3 chemokine receptor i (CX3CRI) signaling pathway. However, whether microglia can influence the maturation and dendritic growth of newborn neurons during hippocampal neurogenesis remains unclear. In the present study, we found that the number of doublecortin-positive cells in the hippocampus was decreased, and the dendritic length and number of intersections in newborn neurons in the hippocampus were reduced in transgenic adult mice with CX3CR1 deficiency (CX3CRl^GFP/GFe). Furthermore, after experimental seizures were induced with kainic acid in these CX3CRl-deficient mice, the expression of c-fos, a marker of neuronal activity, was reduced compared with wild-type mice. Collectively, the experimental findings indicate that the functional maturation of newborn neu- rons during hippocampal neurogenesis in adult mice is delayed by CX3CR1 deficiency. 展开更多
关键词 nerve regeneration FRACTALKINE cx3 chemokine receptor 1 neuronal maturation DENDRITES DOUBLECORTIN synaptic maturation newborn neurons neural regeneration
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A novel complex-high-order graph convolutional network paradigm:ChyGCN
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作者 郑和翔 苗书宇 顾长贵 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第5期665-672,共8页
In recent years,there has been a growing interest in graph convolutional networks(GCN).However,existing GCN and variants are predominantly based on simple graph or hypergraph structures,which restricts their ability t... In recent years,there has been a growing interest in graph convolutional networks(GCN).However,existing GCN and variants are predominantly based on simple graph or hypergraph structures,which restricts their ability to handle complex data correlations in practical applications.These limitations stem from the difficulty in establishing multiple hierarchies and acquiring adaptive weights for each of them.To address this issue,this paper introduces the latest concept of complex hypergraphs and constructs a versatile high-order multi-level data correlation model.This model is realized by establishing a three-tier structure of complexes-hypergraphs-vertices.Specifically,we start by establishing hyperedge clusters on a foundational network,utilizing a second-order hypergraph structure to depict potential correlations.For this second-order structure,truncation methods are used to assess and generate a three-layer composite structure.During the construction of the composite structure,an adaptive learning strategy is implemented to merge correlations across different levels.We evaluate this model on several popular datasets and compare it with recent state-of-the-art methods.The comprehensive assessment results demonstrate that the proposed model surpasses the existing methods,particularly in modeling implicit data correlations(the classification accuracy of nodes on five public datasets Cora,Citeseer,Pubmed,Github Web ML,and Facebook are 86.1±0.33,79.2±0.35,83.1±0.46,83.8±0.23,and 80.1±0.37,respectively).This indicates that our approach possesses advantages in handling datasets with implicit multi-level structures. 展开更多
关键词 raph convolutional network complex modeling complex hypergraph
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