Medicinal plants with hepatoprotective activity in Iranian folk medicine

There are a number of medicinal combinations in the Iranian traditional medicine which are commonly used as tonic for liver.In this review,we have introduced some medicinal plants that are used mainly for the treatment of liver disorders in Iranian folk medicine,with focus on their hepatoprotective effects particularly against CCI_4 agent.In this study,online databases including Web of Science.PubMed.Scopus,and Science Direct were searched for papers published from January 1970 to December 2013.Search terms consisted of medicinal plants,traditional medicine,folk medicine,hepatoprotective.Iran,liver,therapeutic uses,compounds,antioxidant.CCI_4.anti-inflammatory,and antihepatotoxic,hepatitis,alone or in combination.Allium hirtifolium Boiss..Apium graveolens L..Cynara scolyinus.Berberis vulgaris L..,Calendula officinalis,Nigella sativa L..Taraxacum officinale.Tragopogon porrifolius.Prangos ferulacea L..Allium sativum,Marribium vulgare,Ammi majus L..Citrullus lanatus Thunb.Agrimonia eupatoria L.and Primus armeniaca L.are some of the medicinal plants that have been used for the treatment of liver disorders in Iranian folk medicine.Out of several leads obtained from plants containing potential hepatoprotective agents,silymarin,P-sitosterol,betalain,neoandrographolide.phyllanthin.andrographolide.curcumin.picroside.hypophyllanlhin.kutkoside,and glycyrrhizin have been demonstrated to have potent hepatoprotective properties.Despite encouraging data on possibility of new discoveries in the near future,the evidence on treating viral hepatitis or other chronic liver diseases by herbal medications is not adequate.

综合治疗新生儿高胆红素血症疗效及相关指标变化和护理

目的探讨综合治疗新生儿高胆红素血症疗效、相关指标变化及护理。方法新生儿高未结合胆红素血症200例,随机分为两组,对照组84例,观察组116例.对照组治疗采用蓝光照射15~20 h/d,鲁米那5 mg/(kg·d)口服;复方丹参注射液2 ml加入10%葡萄糖10 ml静脉滴注,连用5天。观察组采用蓝光照射15~20 h/d,鲁米那5 mg/(kg·d)口服;茵栀黄2 ml加入10%葡萄糖50 ml静脉滴注。治疗前和治疗7天后抽静脉血检测相关指标。提前强化护理。应用SPSS17.0软件,所获数据采用方差分析、t检验。结果两组新生儿胎粪初排时间比较,P<0.005;胎粪转黄时间比较,P<0.0005。两组第一天血清未结合胆红素比较,P>0.05;两组治疗3天、7天后血清未结合胆红素比较,P均<0.005。对照组治疗前及治疗7天后BUN、Scr变化比较,P均>0.05。对照组治疗前及治疗7天后血CysC、尿CysC变化比较,P均<0.0005。观察组治疗前及治疗7天后BUN变化比较,P<0.05;观察组治疗前及治疗7天后Scr变化比较,P>0.05;观察组治疗前及治疗7天后血CysC、尿CysC变化比较,P均<0.0005。两组治疗7天后BUN、血CysC、尿CysC变化比较,P均>0.05;两组治疗7天后Scr变化比较,P<0.05。对照组治疗前及治疗7天后T3变化比较,P<0.01;对照组治疗前及治疗7天后FT3变化比较,P<0.05;对照组治疗前及治疗7天后T4、FT4、TSH变化比较,P均>0.05。观察组治疗前及治疗7天后T3变化比较,P<0.0005;观察组治疗前及治疗7天后T4变化比较,P<0.05;观察组治疗前及治疗7天后FT3变化比较,P<0.0005;、观察组治疗前及治疗7天后FT4、TSH变化比较,P>0.05。两组治疗7天后T3、T4、FT4、TSH变化比较,P均>0.05;两组治疗7天后FT3变化比较,P<0.005。结论综合治疗和提前强化护理对新生儿高胆红素血症疗效确切而显著,茵栀黄治疗对新生儿体内环境有较好的影响。