RepBoTNet-CESA:An Alzheimer’s Disease Computer Aided Diagnosis Method Using Structural Reparameterization BoTNet and Cubic Embedding Self Attention

Various deep learning models have been proposed for the accurate assisted diagnosis of early-stage Alzheimer’s disease(AD).Most studies predominantly employ Convolutional Neural Networks(CNNs),which focus solely on local features,thus encountering difficulties in handling global features.In contrast to natural images,Structural Magnetic Resonance Imaging(sMRI)images exhibit a higher number of channel dimensions.However,during the Position Embedding stage ofMulti Head Self Attention(MHSA),the coded information related to the channel dimension is disregarded.To tackle these issues,we propose theRepBoTNet-CESA network,an advanced AD-aided diagnostic model that is capable of learning local and global features simultaneously.It combines the advantages of CNN networks in capturing local information and Transformer networks in integrating global information,reducing computational costs while achieving excellent classification performance.Moreover,it uses the Cubic Embedding Self Attention(CESA)proposed in this paper to incorporate the channel code information,enhancing the classification performance within the Transformer structure.Finally,the RepBoTNet-CESA performs well in various AD-aided diagnosis tasks,with an accuracy of 96.58%,precision of 97.26%,and recall of 96.23%in the AD/NC task;an accuracy of 92.75%,precision of 92.84%,and recall of 93.18%in the EMCI/NC task;and an accuracy of 80.97%,precision of 83.86%,and recall of 80.91%in the AD/EMCI/LMCI/NC task.This demonstrates that RepBoTNet-CESA delivers outstanding outcomes in various AD-aided diagnostic tasks.Furthermore,our study has shown that MHSA exhibits superior performance compared to conventional attention mechanisms in enhancing ResNet performance.Besides,the Deeper RepBoTNet-CESA network fails to make further progress in AD-aided diagnostic tasks.

Evaluation of computer aided detection during colonoscopy among Veterans:Randomized clinical trial

BACKGROUND There has been significant interest in use of computer aided detection(CADe)devices in colonoscopy to improve polyp detection and reduce miss rate.AIM To investigate the use of CADe amongst veterans.METHODS Between September 2020 and December 2021,we performed a randomized controlled trial to evaluate the impact of CADe.Patients at Veterans Affairs Palo Alto Health Care System presenting for screening or low-risk surveillance were randomized to colonoscopy performed with or without CADe.Primary outcomes of interest included adenoma detection rate(ADR),adenomas per colonoscopy(APC),and adenomas per extraction.In addition,we measured serrated polyps per colonoscopy,non-adenomatous,non-serrated polyps per colonoscopy,serrated polyp detection rate,and procedural time.RESULTS A total of 244 patients were enrolled(124 with CADe),with similar patient characteristics(age,sex,body mass index,indication)between the two groups.Use of CADe was found to have decreased number of adenomas(1.79 vs 2.53,P=0.030)per colonoscopy compared to without CADe.There was no significant difference in number of serrated polyps or non-adenomatous non-serrated polyps per colonoscopy between the two groups.Overall,use of CADe was found to have lower ADR(68.5%vs 80.0%,P=0.041)compared to without use of CADe.Serrated polyp detection rate was lower with CADe(3.2%vs 7.5%)compared to without CADe,but this was not statistically significant(P=0.137).There was no significant difference in withdrawal and procedure times between the two groups or in detection of adenomas per extraction(71.4%vs 73.1%,P=0.613).No adverse events were identified.CONCLUSION While several randomized controlled trials have demonstrated improved ADR and APC with use of CADe,in this RCT performed at a center with high ADR,use of CADe was found to have decreased APC and ADR.Further studies are needed to understand the true impact of CADe on performance quality among endoscopists as well as determine criteria for endoscopists to consider when choosing to adopt CADe in their practices.

Applications of Computer Aided Modeling Techniques to Complex ICE Components

Design of internal combustion engine (ICE) components is one of the earliest and also the most active areas in which computer aided modeling techniques are applied. Computer aided modeling techniques could provide requisite information for follow up designing segments such as structural analysis, design of technological process and manufacturing etc, and thereby lead to the reduction of product design period and the quality and reliability improvement of ICE components. So the developing situations of ICE components' 2 D drafting, 3 D modeling of ICE, overall CAD of ICE as well as component design expert system etc. are surveyed, which are the typical applications of computer aided modeling techniques in ICE component design process, and some existent problems and tasks are pointed out so as to make some references for the further research work.

Optimization of Vehicle Side Curtain Airbag Module Based on Computer Aided Engineering

Compared with other kinds of airbags, curtain airbag（CAB） has more complex structures and larger coverage area. The product development process depends on many module tests, sled tests and full size vehicle tests. Computer aided engineering（CAE） technology can replace tests to a great extent, also save test costs and product development time. This paper introduces the way of setting up simulation models and application of static deployment tests and free motion headform（FMH） tests to verify simulation models. In the CAB simulation, uniform pressure airbag models and computational fluid dynamics（CFD） models are all used. The uniform pressure airbag models are not able to simulate the pressure difference among different parts inside the cushion during inflating process. CFD-based CAB models are used to help the curtain airbag optimization design. Based on effective CAE simulation, the optimization analyses related to diffuser tube parameters, inflator mass flow rate and cushion folding patterns are discussed and performed in different cases. The optimization result shows that the proposed techniques are helpful to the parametric optimization design of side curtain airbag module in curtain airbag development process.

Recent advances of variational model in medical imaging and applications to computer aided surgery

In this paper, we review some mathematical models in medical image processing. Due to the superiority in modeling and computation, variational methods have been proven to be powerful techniques, which have been extremely popular and dramatically improved in the past two decades. On one hand, many models have been proposed for nearly all kinds of applications. On the other hand, a lot of models can be globally optimized and also many computation tools have been introduced. Under the variational framework, we focus on two basic problems in medical imaging： image restoration and segmentation, which are core components for kinds of specific tasks. For image restoration, we discuss some models on both additive and multiplicative noises. For image segmentation, we review some models on both whole image segmentation and specific target delineation, with the later being a key step in computer aided surgery. Additionally, we present some models on liver delineation and give their applications to living donor liver transplantation.

Computer aided diabetic retinopathy detection based on ophthalmic photography: a systematic review and Meta-analysis

AIM: To ensure the diagnostic value of computer aided techniques in diabetic retinopathy(DR) detection based on ophthalmic photography(OP). METHODS: PubM ed, EMBASE, Ei village, IEEE Xplore and Cochrane Library database were searched systematically for literatures about computer aided detection(CAD) in DR detection. The methodological quality of included studies was appraised by the Quality Assessment Tool for Diagnostic Accuracy Studies(QUADAS-2). Meta-Di Sc was utilized and a random effects model was plotted to summarize data from those included studies. Summary receiver operating characteristic curves were selected to estimate the overall test performance. Subgroup analysis was used to identify the efficiency of CAD in detecting DR, exudates(EXs), microaneurysms(MAs) as well as hemorrhages(HMs), and neovascularizations(NVs). Publication bias was analyzed using STATA. RESULTS: Fourteen articles were finally included in this Meta-analysis after literature review. Pooled sensitivity and specificity were 90%(95%CI, 85%-94%) and 90%(95%CI, 80%-96%) respectively for CAD in DR detection. With regard to CAD in EXs detecting, pooled sensitivity, specificity were 89%(95%CI, 88%-90%) and99%(95%CI, 99%-99%) respectively. In aspect of MAs and HMs detection, pooled sensitivity and specificity of CAD were 42%(95%CI, 41%-44%) and 93%(95%CI, 93%-93%) respectively. Besides, pooled sensitivity and specificity were 94%(95%CI, 89%-97%) and 87%(95%CI, 83%-90%) respectively for CAD in NVs detection. No potential publication bias was observed. CONCLUSION: CAD demonstrates overall high diagnostic accuracy for detecting DR and pathological lesions based on OP. Further prospective clinical trials are needed to prove such effect.

MULTI-AGENT COMPUTER AIDED ASSEMBLY PROCESS PLANNING SYSTEM FOR SHIP HULL

A multi agent computer aided assembly process planning system (MCAAPP) for ship hull is presented. The system includes system framework, global facilitator, the macro agent structure, agent communication language, agent oriented programming language, knowledge representation and reasoning strategy. The system can produce the technological file and technological quota, which can satisfy the production needs of factory.

COMPUTER AIDED ANALYSIS FOR COLD ROLL FORMING THIN CHANNEL SECTION

Cold roll forming is a complicated metal processing, and its is very difficult to simulate the forming process. Based on the Updated-Lagrange method in the deformation mechanics, an elastic-plastic large deformation spline finite strip method is developed to analyze cold roll forming of a thin channel section. The longitudinal membrane strain values on the edge of the deformed strip for four one-pass sequences in different fold angles are got. Simulated results are compared with the results from previously conducted experiments. The deviation of the simulated peak strain values is within 30% compared with the experimental results.

Case-based intelligent computer aided design system of welding machinery

The procedure during complex system plan design of welding position-locating machine is studied in this paper. The main difficulties in designing welding position-locating machine utilizing computer are discussed as well. A method of case-based intelligent CAD system for welding position-locating machine ( WMICAD) is put forward through wide research on design methodology. Object-oriented programming method is also applied to Ms system. The basic idea and realizing method are described.

THE APPLICATION OF THE COMPUTER AIDED ANALYSIS IN THE DESIGN OF COALMINE MACHINERY LINKAGES

This paper gives and verifies a mathematical model with only one argument which determines the movement parameters of any point in a plane four-bar linkage on the basis of the analysis of mining machinery linkages. C A A (computer aided analysis) based on the mathemetical model can be used to make not only the quick and accurate analysis and design of mining machinery linkages but also the movement analysis and optimization design of any other plane four-bar linkage.

An Architecture of Computer Aided Process Planning System Integrated with Scheduling Using Decision Support System

Process planning and scheduling are two major plann in g and control activities that consume significant part of the lead-time, theref ore all attempts are being made to reduce lead-time by automating them. Compute r Aided Process Planning (CAPP) is a step in this direction. Most of the existin g CAPP systems do not consider scheduling while generating a process plan. Sched uling is done separately after the process plan has been generated and therefore , it is possible that a process plan so generated is either not optimal or feasi ble from scheduling point of view. As process plans are generated without consid eration of job shop status, many problems arise within the manufacturing environ ment. Investigations have shown that 20%～30% of all process plans generated are not valid and have to be altered or suffer production delays when production sta rts. There is thus a major need for integration of scheduling with computer aide d process planning for generating more realistic process plans. In doing so, eff iciency of the manufacturing system as a whole is expected to improve. Decision support system performs many functions such as selection of machine too ls, cutting tools, sequencing of operations, determination of optimum cutting pa rameters and checking availability of machine tool before allocating any operati on to a machine tool. The process of transforming component data, process capabi lity and decision rules into computer readable format is still a major obstacle. This paper proposes architecture of a system, which integrates computer aided p rocess-planning system with scheduling using decision support system. A decisio n support system can be defined as " an interactive system that provides the use rs with easy access to decision models in order to support semi-structured or u nstructured decision making tasks".

A Computer Aided System for Simulating Weld Metal Solidification Crack

A computer-aided system for simulating weld solidification crack has been developed by which a welding engineer can carry out the welding solidification crack simulation on the basis of a commercial finite element analysis software package. its main functions include calculating the heat generations of the moving arc. mesh generation, calculating stress-strain distributions with element rebirth technique.

Applied computer aided system for hotplate butt welding of plastics

This paper illustrates the construction and application of the applied computeraided .system for hotplate butt welding of plastics with regard to inquiry, imitation and Optimization.

A New Computer Aided Volleyball Training System Based on Pattern Recognition Model

This paper proposes the novel computer aided volleyball training system based on pattern recognition model. In general the quality of volleyball training at the same time, we should strengthen coordination, mobile power, quality training, strengthen mobile exercises, moving fast and flexible to overcome the sudden fall of soft volleyball on the defensive and pilling adverse, such practice can be used for mobile.Strengthen the strength training, enhance the strength of the upper and lower limbs, improve the team＇ s bounce and batting speed is conducive to compete for the advantage of the Internet, better undermine the defense. With the help of the proposed system, the training process will be more effective, and the performance will be verified in the later discussions.

Computer Aided Design and Performance Analysis of Inverse Fluidized Bed Biofilm Reactors with Special Reference to Bioplastic Synthesis

Poly Laevo Lactic Acid (PLLA), in spite of being an excellent bioplastic, has exorbitantly high market price due to the high cost of raw material (lactose, glucose, sucrose). Hence, its manufacture is being attempted starting from waste effluents such as cheese whey and molasses. Earlier studies on the same in fluidized bed and semifluidized bed biofilm reactors yielded encouraging results. The present study therefore involves design and analysis of inverse fluidized bed biofilm reactors for lactic acid synthesis. The performance features of the bioreactor have been studied both mathematically as well as experimentally. The inverse fluidized bed biofilm reactor has been found to provide more than 75% conversion of sucrose/lactose even at high capacities (high feed flow rates) exceeding 56,000 L/hr, within a reasonably low reactor volume. The fractional substrate conversion increases, though sluggishly, with increase in feed flow rate due to bed expansion and also with increase in cell mass concentration in biofilm due to enhancement in intrinsic rate of bioconversion. The inverse fluidized bed biofilm reactor of proposed design could be safely recommended for the commercial synthesis of polymer grade lactic acid from waste effluents such as cheese whey and molasses. The low operating cost of the bioreactor (due to downflow mode of operation) enhances the economy of the process. This would also help in significantly lowering the market price of the green plastic (PLLA) and shall promote its large scale manufacture and utilisation.

A Brief Analysis of the Translator’s Subjectivity in the Process of Computer Aided Translation

In the era of globalization and big data,the demand for translation is growing rapidly,and the task of translators is be⁃coming increasingly burdensome.The emergence of computer aided translation technology provides great convenience for transla⁃tion work.The main body of computer aided translation process is the translator,which avoids many drawbacks in machine transla⁃tion.This paper aims to have a brief analysis of the translator's subjectivity in the process of computer aided translation,which will be helpful for the development of the computer aided translation technology.

Computer Aided Software Engineering(CASE)for CAD Systems Production

In the paper the basic elements of CAD systems from software point of view are dis- cussed.The creation and next the modification of CAD systems needs specialized software tools.In the paper the idea computer Aided Software Engineering(CASE)for CAD systems production and practi- cal software realization of such a software tool is considered.The main element of this tool is special program provided for convenient storage and modification of CAD source program.In the paper the simple examples are presented and discussed.

Application of computer aided 3D simulation technique for complicated foot and ankle fractures

Objective To investigate the effect of computer aided 3D simulation technique for treating complicated foot and ankle fractures precisely.Methods From November 2007 to August 2009,255 patients with complicated foot and ankle fractures

COMPUTER AIDED INSPECTION PLANNING

Computer aided inspection planning (CAIP) is an approach to the automation of inspectionplanning. This paper summaries research approaches to automation of inspection planning activitiesand current research status of CAIP technology. BHINSP a knowledge based expert inspectionplanning system , which is being developed in Beijing University of Aeronautics & Astronautics , is in-troduced. The integration of BHINSP with CAD, CMM is discussed.

COMPUTER AIDED DESIGN OF AIRCRAFT CABIN LAYOUT

The reasonability of cabin layout is studied according to the ergonomic theory on micro-computer. This system includes the anthropometric model,modeling of aircraft seats and cabin,interactive ergonomic analyses on effect.