Training Mode of Design Talents under the Concept of Regional Revitalization and Industrial Upgrading

Based on the background of the revitalization of Northeast China and industrial transformation,with the goal of serving society with design,leading the future with design,and revitalizing the economy with design,we adhere to the innovative,comprehensive and cultural design talent cultivation concept,fully practice the“student-centered,output-oriented,continuously-improving”educational philosophy taking quality as the first priority,and continuously improve the theoretical system and implementation path for cultivation of postgraduate talents in design science,hoping to optimize the entire process of talent cultivation.Meanwhile,on the basis of“fostering character and civic virtue,cultivating people in a three-all manner,and cultivating people from five aspects simultaneously”,we cultivate high-quality design talents with brand-new models and ideas,through a series of educational reform measures,such as strategic cooperation,resource integration,systematic sorting,quality improvement,standard formulation,strengthening characteristics,platform construction,so that the quality of talents and social development can be perfectly integrated and mutually assist each other to achieve a win-win effect,and the training of design talents can be implemented and serve the society.

Research on Key Points of Design of Standard Plants in Modern Industrial Parks Under the Background of Promoting the Development of New Quality Productive Forces

With the progress of science and technology and the acceleration of industrialization,the modern industrial park is an important carrier of industrial development.The importance of its standard plant design has become increasingly prominent.With the development of new quality productive forces as the background,this research deeply discusses the key points of standard plant design in modern industrial parks.This paper uses literature review and case analysis to systematically analyze the important role of standard plant design in developing new quality productive forces in modern industrial parks and puts forward suggestions for optimizing design.It is found that the rationality,intelligence,and environmental protection of plant design are the key factors affecting the development of new quality productive forces.The paper summarizes the core points of modern industrial park standard plant design to provide a reference for the future development of related industries.

The computer-aided design method of cabinet based on style imagery

Due to the practical problems of the high costs and the long development cycle of China’s cabinet production,a computer-aided design method of the cabinet based on style imagery is proposed.According to the principle of the conjoint analysis method, the rough set theory and the weight coefficient of different components of the cabinet,a multi-dimensional model of style imagery to evaluate the cabinet is built. Then the related constants of style imagery are calculated and the cabinet components library is also built by the three-dimensional modeling.Finally,with recombinant technology and the mapping model between cabinet style and external characteristics,the prototype system based on Visual Studio is proposed.This system actualizes the bidirectional reasoning between product style imagery and the shape features,which can assist designers to produce more creative designs,greatly improve the efficiency of cabinet development and increase the profits of companies.

Brief Introduction to Industrial Design Aesthetics

The paper proposes the idea that in the primary stage of industrial product design, the aesthetic nature of the product should be grasped. In addition, the paper poses two questions about aesthetic nature industrial design: first, what is the object of industrial design aesthetics? Second, what are the characteristics of design aesthetics of industrial products?

Application of computer-aided engineering optimum design method in aluminum profile extrusion mould

The finite element analysis and the optimum design of aluminum profile extrusion mould were investigated using the ANSYS software and its parameterized modeling method. The optimum dimensions of the mould were obtained. It is found that the stress distribution is very uneven, and the stress convergence is rather severe in the bridge of the aluminum profile extrusion mould. The optimum height of the mould is 70.527 mm, and the optimum radius of dividing holes are 70.182 mm and 80.663 mm. Increasing the height of the mould in the range of 61.282 mm to 70.422 mm can prolong its longevity, but when the height is over 70.422 mm, its longevity reduces.

Integrated computer-aided formulation design:A case study of andrographolide/cyclodextrin ternary formulation

Current formulation development strongly relies on trial-and-error experiments in the laboratory by pharmaceutical scientists,which is time-consuming,high cost and waste materials.This research aims to integrate various computational tools,including machine learning,molecular dynamic simulation and physiologically based absorption modeling(PBAM),to enhance andrographolide(AG)/cyclodextrins(CDs)formulation design.The light GBM prediction model we built before was utilized to predict AG/CDs inclusion's binding free energy.AG/γ-CD inclusion complexes showed the strongest binding affinity,which was experimentally validated by the phase solubility study.The molecular dynamic simulation was used to investigate the inclusion mechanism between AG andγ-CD,which was experimentally characterized by DSC,FTIR and NMR techniques.PBAM was applied to simulate the in vivo behavior of the formulations,which were validated by cell and animal experiments.Cell experiments revealed that the presence of D-α-Tocopherol polyethylene glycol succinate(TPGS)significantly increased the intracellular uptake of AG in MDCKMDR1 cells and the absorptive transport of AG in MDCK-MDR1 monolayers.The relative bioavailability of the AG-CD-TPGS ternary system in rats was increased to 2.6-fold and 1.59-fold compared with crude AG and commercial dropping pills,respectively.In conclusion,this is the first time to integrate various computational tools to develop a new AG-CD-TPGS ternary formulation with significant improvement of aqueous solubility,dissolution rate and bioavailability.The integrated computational tool is a novel and robust methodology to facilitate pharmaceutical formulation design.

Computer-Aided Design of Some Advanced Steels and Cemented Carbides

Thermodynamic and kinetic study on TRIP （transformation induced plasticity） steels, cemented carbides and mold steel for plastics were carried out in order to design modern advanced materials. With the sublattice model, equilibrium compositions of ferrite and austenite phases in TRIP steels, as well as volume fraction of austenite at inter-critical temperatures for different time were calculated. Concentration profiles of carbon, manganese, aluminum and silicon in the steels were also estimated in the lattice fixed frame of reference. The effect of Si and Mn on TRIP was discussed according to thermodynamic and kinetic analyses. In order to understand and produce the graded nanophase structure of cemented carbides, miscellaneous phases in the M-Co-C （M= Ti, Ta, Nh） systems and Co-V-C system were modeled. Solution parameters and thermodynamic： properties were listed in detail. The improvement of machining behavior of prehardened mould steel for plastics was obtained by computer-aided composition design. The results showed that the matrix composition of large-section prehardened mould steel for plastic markedly influences the precipitation of non-metallic inclusion and the composition control by the aid of Thermo-Calc software package minimizes the amount of detrimental oxide inclusion. In addition, the modification of calcium was optimized in composition design.

Computer-aided designing and manufacturing of advanced steels

Suitable optimization and simulation were performed using a powerful software package with a mature database as well as modem measurement facilities, which led to the successful designing and manufacturing of advanced steels. In the course of designing, the composition of a large section of prehardened mold steel for plastics was estimated so as to lower the quantities of oxide inclusions to change the type of carbides and to raise the machinability. The composition and process were adjusted to obtain satisfactory surface quality for the prevailing galvanization in transformation-induced plasticity （TRIP） steel. The refuting process of low-carbon steel was simulated in the light of both Thermo-Calc and Factsage. Thermodynamic and kinetic analyses were always conducted during the test and the procedure.

Precoder Design and Impulsive Noise Mitigation Scheme for Industrial Wireless Communications

In industrial wireless scenarios,the impulsive noise(IN)incurred by machine running or operation causes a serious influence on the powerlimited industrial wireless communications.It is challenging to ensure efficient and reliable transmission with quality of service(QoS)guarantee for machinetype communication devices(MTCDs).Considering the IN in the industrial process,this paper establishes the multiuser multiple-input single-output(MU-MISO)orthogonal frequency division multiplexing(OFDM)system model,which combines transmitter and receiver design.Two precoding schemes are designed to improve communication effectiveness at the transmitter.More specifically,the precoder design scheme which combines semi-definite relaxation(SDR)with difference-of-two-convex-function(D.C.)iterative algorithm,is developed by utilizing the Dinkelbach method to improve the system effectiveness.To decrease the computational complexity,we devise the quadratic-based fractional programming(QFP)algorithm,which decouples the variables by using a quadratic transform method.On this basis,the IN mitigation scheme is studied to reduce the system error rate(SER)at the receiver.With the goal of improving the reliability of industrial wireless communications,we propose a hybrid nonlinear IN mitigation(HNINM)scheme and then derive its closed-form expression of SER.The simulation results show that the proposed QFP algorithm achieves superior performance while the HNINM scheme decreases the SER of industrial wireless communications.

A Computer-aided Design System for Framed-mould in Autoclave Processing

The general computer-aided design （CAD） software cannot meet the mould design requirement of the autoclave process for composites, because many parameters such as temperature and pressure should be considered in the mould design process, in addition to the material and geometry of the part. A framed-mould computer-aided design system （FMCAD） used in the autoclave moulding process is proposed in this paper. A function model of the software is presented, in which influence factors such as part structure, mould structure, and process parameters are considered; a design model of the software is established using object oriented （O-O） technology to integrate the stiffness calculation, temperature field calculation, and deformation field calculation of mould in the design, and in the design model, a hybrid model of mould based on calculation feature and form feature is presented to support those calculations. A prototype system is developed, in which a mould design process wizard is built to integrate the input information, calculation, analysis, data storage, display, and design results of mould design. Finally, three design examples are used to verify the prototype.

A Novel Human Antibody,HF,against HER2/erb-B2 Obtained by a Computer-Aided Antibody Design Method

Fully human antibodies have minimal immunogenicity and safety profiles.At present,most potential antibody drugs in clinical trials are humanized or fully human.Human antibodies are mostly generated using the phage display method(in vitro)or by transgenic mice(in vivo);other methods include B lymphocyte immortalization,human–human hybridoma,and single-cell polymerase chain reaction.Here,we describe a structure-based computer-aided de novo design technology for human antibody generation.Based on the complex structure of human epidermal growth factor receptor 2(HER2)/Herceptin,we first designed six short peptides targeting the potential epitope of HER2 recognized by Herceptin.Next,these peptides were set as complementarity determining regions in a suitable immunoglobulin frame,giving birth to a novel anti-HER2 antibody named "HF,"which possessed higher affinity and more effective anti-tumor activity than Herceptin.Our work offers a useful tool for the quick design and selection of novel human antibodies for basic mechanical research as well as for imaging and clinical applications in immune-related diseases,such as cancer and infectious diseases.

A Method for Solving Computer-Aided Product Design Optimization Problem Based on Back Propagation Neural Network

Because of the powerful mapping ability, back propagation neural network (BP-NN) has been employed in computer-aided product design (CAPD) to establish the property prediction model. The backward problem in CAPD is to search for the appropriate structure or composition of the product with desired property, which is an optimization problem. In this paper, a global optimization method of using the a BB algorithm to solve the backward problem is presented. In particular, a convex lower bounding function is constructed for the objective function formulated with BP-NN model, and the calculation of the key parameter a is implemented by recurring to the interval Hessian matrix of the objective function. Two case studies involving the design of dopamine β-hydroxylase (DβH) inhibitors and linear low density polyethylene (LLDPE) nano composites are investigated using the proposed method.

The combination of user centered design and industrial design: Balance between subjective and objective design

Traditional Industrial Design has been an important aspect in the New Product Development process within the last dec- ades. User centered design is a growing research field for product innovation which needs support from both design knowledge and research methodologies. Both TID and UCD focus on user＇s perspective when doing multi-disciplinary work. They take care of style, usability, and balancing the users need and reality. The skills from TID help design expression and realization to communicate effi- ciently with other participants by informative images and real prototypes. The methods from UCD help the idea generation and op- portunity discoveries by facilitating workshops and conducting interview with participants. TID and UCD represent different per- spectives of the subjective and the objective respectively.

Analysis of the method on industrial design guided by individual spontaneous behavior

There is a close relationship between individual spontaneous behavior and Industrial design. As individual spontaneous behavior can sent especial meaning for industrial design, there is a great necessity for creating design guided by this behavior. The design method carries out in four steps, first step is to focus on the analysis of individual action phase, pay attention to the explora- tion of the relationship between actions and tool ,and then list the importance order in the action phase, the third step is to take out the in-depth anatomical analysis of the stage, analyze the reason of the operational difficulty .and at last carries out the design concept to resolve the problem. All in all, this method revolves around the main stage of spontaneous behavior, and analyzes it in interim and solves the problem in stage.

A Strategic Study of Establishing the Industrial Needs in Pattern Design and Technology in China's Mainland

Pattern design and technology play a very important role in the garment industry. In order to improve the level of pattern making and design of the garment industry, a survey was conducted to investigate the industrial needs in pattern design and technology in China's Mainland. The data were collected from the employers and employees from the garment industry and students in the major of fashion and clothing studies. It indicated that there was a gap between the employer and employee, especially the requirements of the industrial needs and the course contents covered by the tertiary schools. The employers expected to recruit more experienced pattern designers, at the same time, they were not reluctant to hire fresh graduates and spent more resources on the training of employees. The students knew little about their employment situation of the garment industry, spent too little time on the course study and learned too little practical skills in pattern design. They could not make use of the knowledge which prevented them from being employed by the garment industry. Efforts should be taken by both the tertiary schools and the garment industry. The students should be aspirated towards the profession of pattern cutters and the syllabuses of pattern making should be more practical and industrial orientated. The solution might benefit the garment industry a lot in a long run.

Study on ＂Integration of Informatization and Industrialization＂ Characteristics and Its Interaction Relationship with Industrial Design

The ＂integration of informatization and industrialization＂ is a constant development process. In China, the integration of industrial economy and information economy is an inevitable trend of economy development. The social formation of the current industrial society in China will inevitably transform into the social formation of the integration of industrial society and information society. The ＂integration of informatization and industrialization＂ provides necessary technology for economic development,which makes the society have an overall change. This paper tries to make a comparison of the basic features of different formations from the historical development process of the era, in order to summarize the basic characteristics of ＂integration of informatization and industralization＂ and its interaction relationship with industrial design.

Computer-Aided Design and Fabrication of Finger Prosthesis

Custom-made esthetic finger prostheses, which are used for rehabilitation of patients with missing or impaired fingers, have been fabricated manually. However, such fabrication is time-consuming and requires manual skill. Here we propose a computer-aided method for fabricating finger pros-theses to save time and allow fabrications that do not require considerable manual skill. In this method, the dimensions of a patient’s healthy finger on the contralateral hand are first measured using a caliper. Using these dimensions, a three-dimensional model is constructed for fabricating a prosthesis for the patient’s impaired finger. Using the 3D model, a mold is designed using 3D modeling tools and a computer-aided design system. The resulting mold is then fabricated using a 3D printer. A finger prosthesis is fabricated by pouring silicone resin into the mold. A finger prosthesis for a volunteer was experimentally fabricated according to the proposed method. To evaluate the size and shape of the finger prosthesis, the difference between the finger prosthesis and the original finger of the volunteer was analyzed. Because the average difference between them was 0.25 mm, it was concluded that the proposed method could be used to fabricate a finger prosthesis of adequate size and shape.

Design of Industrial Floors—Review of Guidelines, Special Designing Issues (Part 1)

We are placing more and more emphasis on the design of industrial floors when designing the structure of buildings. Currently there are only a few approved designing guidelines that practicing engineers can use to easily design industrial floors. Rather the best practice is that the manufacturers of certain products (concrete fibre reinforcement, dilatation joints) carry out the more or less professional designing. In addition, there are numerous incurring questions in connection with applying the internationally approved guidelines in terms of applicability and reliability. Our paper is based on years of experience in designing industrial floors. In the first part the main guidelines, their characteristics and opportunities of application are discussed. In the second part we take a closer look at the most common TR34 British guideline, presenting its most significant designing formulas, which support engineering practitioners in carrying out the design of industrial floors on their own. In the third part we demonstrate advanced finite element analyses, comparing results with real sized experiments and with results of the guidelines.

The Industrial Heritage and the New Architecture： Teaching, Researching, Designing the Place Identity

The new architecture may provide unusual opportunities for the abandoned areas involved by former industrial processes, both in the city centers and in the landscape. In fact, it may create new centralities and give new collective function for deprived areas. The case study of the architectural and educational project for a new museum park devoted to the technique and the science in the Apennine＇ s landscape near Parma （Italy） may give an interesting point of view about the role of the teaching and the research of the architecture in the former industrial heritage, and to avoid the abandonment and the pauperization of the territory around.

Innovative Thinking on the Renovation Design of Old Industrial Building Space

The current study investigated the value and significance of the existence of the old industrial buildings, as well as the necessity and difficulty to renovate the design. Combined with successful cases, this study analyzed and showed that one should not only deal with the relationship between the original architectural style and construction of modem cities in the process of renovation design of the old industrial building space. More attention should also be paid to create new space to meet the functional requirements of the modem features, and then complete substantial renovation of old industrial building space through the innovative design. In the use of aesthetic innovative design for the renovation of the old industrial building space, people must respect the space of old industrial buildings as the prerequisite of the renovation design. It is needed to expound the local space reconstruction methods and design principles respectively on the basis of respect. And then one should grasp the whole space and make the structured design and reasonable use according to the new space functional requirements of different functional areas. This paper attempted to learn from environmental art study on the renovation of old industrial buildings space and in terms of innovative design. The authors explored the innovative thinking on the renovation design of old industrial building space through the analysis of the reality.