Analysis on clinically drug-used law for lung-intestine related diseases

OBJECTIVE:To analyze the application laws of clinical drugs by descriptive statistical method with the clinical literatures guided by "lung being connected with large intestine" used as the object.METHODS:Retrievepubliclypublishedclinicalliteratures about "lung being connected with large intestine"inrecent30years,establishthedatabaseofclinical literature,and study on the clinically drug-used lawsbydescriptivestatisticalanalyticmethod.RESULTS:The common high frequent drugs used for the lung-intestine related diseases were Gualou(Ructus Trichsanthis),Dahuang(Radix et Rhizoma),Kuxingren(Semen Armeniacae Amarum),Gancao(Radix Glycyrrhizae),Houpu(Cortex Magnoliae Officinalis),Zhishi(Fructus Aurantii Immaturus).For the different clinical syndrome types,in the commonly used drugs there were different characteristics,reflecting the principle of TCM syndrome differentiation treatment.CONCLUSION:The common high frequent drugs used for the lung-intestine related diseases are Gualou(Fructus Trichsanthis),Dahuang(Radix et Rhizoma),Kuxingren(Semen Armeniacae Amarum),Gancao(Radix Glycyrrhizae),Houpu(Cortex Magnoliae Officinalis),Zhishi(Fructus Aurantii Immaturus),which are commonly-used drugs for the lung-intestine related diseases,with differences for different syndrome types.

A Comparative Study of The Regular Pattern of Syndrome and Treatment of Lung-intestine Related Diseases in Ancient and Modern Medical Cases Based on Data Mining

Objective: To analyze the similarities and differences of the applications of "the lung and large intestine being interior-exteriorly related"between the ancient and modern clinical practices, and to reveal the theory meaning.Method: Based on the ancient and modern medical cases database, 245 ancient medical records and 373 modern medical records were studied with the general statistical description and analysis of association rules, and the results were compared to summarize the similarities and differences of the regular pattern of syndrome and treatment on lung-large intestine related diseases in ancient and modern medical records.Results: In modern medical cases, intestinal diseases appeared with the main symptom of constipation due to deficiency of lung qi and qi stagnation of large intestine were always treated by purgation together with replenishing and restoring lung qi. In ancient medical cases, large intestine heat was always caused by lung heat and a variety of diarrhea symptoms appeared. They were always treated by clearing heat and moistening lungs. In addition, the symptom of bound stool caused by qi stagnation of large intestine due to lung qi stagnation was always treated by lowering lung qi to regulate and smooth large intestine qi. And Armeniae Amarum Semen was used by both as a core medicinal herb.Conclusion: Ascending-descending of qi movement is the core of the lung and large intestine relationship. In other words, the lung and the large intestine communicate through qi.

从“脑肠相通”假说探讨肺性脑病辨治

肺性脑病为慢性阻塞性肺疾病后期的严重阶段,此病发展影响到神经系统时,往往出现肠道运动功能异常,或肠道功能异常早于神经系统症状出现。它或者是主要致病机理,或者是病情恶化的主要因素。"脑肠相通"假说为临床预防和辨治肺性脑病提供了新的思维模式,即采取脑病问肠,肠病询脑,脑肠同治措施,从而达到"通腑安脑,脑安腑畅"的目的。