目的本研究通过meta分析评估经皮内镜椎间孔入路微创手术(PETFA)治疗腰椎间盘突出症的疗效,为临床提供科学依据。方法检索PubMed、EMbase、Web of Science、CNKI和万方数据库,筛选随机对照试验(RCTs),使用Rev Man 5.3软件,采用相对风险(...目的本研究通过meta分析评估经皮内镜椎间孔入路微创手术(PETFA)治疗腰椎间盘突出症的疗效,为临床提供科学依据。方法检索PubMed、EMbase、Web of Science、CNKI和万方数据库,筛选随机对照试验(RCTs),使用Rev Man 5.3软件,采用相对风险(RR)和标准化平均差异(SMD)进行统计。结果纳入8篇高质量研究,涉及462例患者。结果显示PETFA手术的多项指标均优于传统手术,包括更短的手术时间[平均差(MD)=-6.51],较少的术中出血(MD=-7.09),更短的住院时间(MD=-2.85),以及更佳的术后疼痛缓解(MD=-1.68)和功能恢复(MD=-0.89)。结论PETFA微创手术在治疗腰椎间盘突出症方面具显著优势,推荐在临床中广泛应用。展开更多
BACKGROUND Disc herniation(DH)is a fragment of the disc nucleus that is pushed out of the annulus into the spinal canal due to a tear or rupture in the annulus.It is a common cause of lumbar and leg pains.Substantial ...BACKGROUND Disc herniation(DH)is a fragment of the disc nucleus that is pushed out of the annulus into the spinal canal due to a tear or rupture in the annulus.It is a common cause of lumbar and leg pains.Substantial advancements have been made to determine the cause of DH and to ensure accurate diagnosis,imaging,and treatment of this condition.Total endoscopic discectomy is an alternative surgical technique that is less invasive.AIM To study the optimal approach for a total endoscopic discectomy and its influence on lumbar and leg function in DH patients.METHODS This prospective study enrolled 120 patients with lumbar DH who were treated in our hospital from February 2018 to January 2021.All patients were randomly divided into the following two groups:The observation group,comprising 62 patients who underwent surgery using the interlaminar approach,and the control group,comprising 58 patients who were operated through the foramina approach.The treatment effects,perioperative indicators,functional recovery,pain,and quality of life were compared between the two groups.RESULTS The treatment effect in the observation group(93.55%)was significantly better than that in the control group(77.59%).There was no difference in the operative time and intraoperative blood loss amount between the two groups(P>0.05).The hospitalization time of the observation group(4.34±1.33 d)was significantly shorter than that of the control group(5.38±1.57 days)(P<0.05).The Japanese Orthopaedic Association and Oswestry Disability Index scores decreased significantly in both groups after treatment,but the scores were lower in the observation group than in the control group.The visual analog scale scores of the lower back and legs of the two groups were significantly reduced after treatment,but scores were lower in the observation group(2.18±0.88 in the lower back and 1.42±0.50 in the leg)than in the control group(3.53±0.50 in the lower back and 2.21±0.52 in the leg).A short form of the Arthritis Impact Measurement Scales 2 measurement scale(AIMS2-SF)score and Barthel index of the lower back of the two groups increased significantly after treatment,with the observation group having a significantly higher AIMS2-SF score(95.16±1.74)and Barthel index(97.29±1.75)than the control group(84.95±2.14 and 89.16±2.71,respectively)(P<0.05).CONCLUSION Through total endoscopic discectomy with the interlaminar approach,the degree of pain in the waist and leg was reduced,and the lumbar function considerably recovered.展开更多
文摘目的本研究通过meta分析评估经皮内镜椎间孔入路微创手术(PETFA)治疗腰椎间盘突出症的疗效,为临床提供科学依据。方法检索PubMed、EMbase、Web of Science、CNKI和万方数据库,筛选随机对照试验(RCTs),使用Rev Man 5.3软件,采用相对风险(RR)和标准化平均差异(SMD)进行统计。结果纳入8篇高质量研究,涉及462例患者。结果显示PETFA手术的多项指标均优于传统手术,包括更短的手术时间[平均差(MD)=-6.51],较少的术中出血(MD=-7.09),更短的住院时间(MD=-2.85),以及更佳的术后疼痛缓解(MD=-1.68)和功能恢复(MD=-0.89)。结论PETFA微创手术在治疗腰椎间盘突出症方面具显著优势,推荐在临床中广泛应用。
基金Science and Technology Support Plan of Guizhou Science and Technology Department,No.[2019]2812and National Natural Science Foundation of China,No.82060415.
文摘BACKGROUND Disc herniation(DH)is a fragment of the disc nucleus that is pushed out of the annulus into the spinal canal due to a tear or rupture in the annulus.It is a common cause of lumbar and leg pains.Substantial advancements have been made to determine the cause of DH and to ensure accurate diagnosis,imaging,and treatment of this condition.Total endoscopic discectomy is an alternative surgical technique that is less invasive.AIM To study the optimal approach for a total endoscopic discectomy and its influence on lumbar and leg function in DH patients.METHODS This prospective study enrolled 120 patients with lumbar DH who were treated in our hospital from February 2018 to January 2021.All patients were randomly divided into the following two groups:The observation group,comprising 62 patients who underwent surgery using the interlaminar approach,and the control group,comprising 58 patients who were operated through the foramina approach.The treatment effects,perioperative indicators,functional recovery,pain,and quality of life were compared between the two groups.RESULTS The treatment effect in the observation group(93.55%)was significantly better than that in the control group(77.59%).There was no difference in the operative time and intraoperative blood loss amount between the two groups(P>0.05).The hospitalization time of the observation group(4.34±1.33 d)was significantly shorter than that of the control group(5.38±1.57 days)(P<0.05).The Japanese Orthopaedic Association and Oswestry Disability Index scores decreased significantly in both groups after treatment,but the scores were lower in the observation group than in the control group.The visual analog scale scores of the lower back and legs of the two groups were significantly reduced after treatment,but scores were lower in the observation group(2.18±0.88 in the lower back and 1.42±0.50 in the leg)than in the control group(3.53±0.50 in the lower back and 2.21±0.52 in the leg).A short form of the Arthritis Impact Measurement Scales 2 measurement scale(AIMS2-SF)score and Barthel index of the lower back of the two groups increased significantly after treatment,with the observation group having a significantly higher AIMS2-SF score(95.16±1.74)and Barthel index(97.29±1.75)than the control group(84.95±2.14 and 89.16±2.71,respectively)(P<0.05).CONCLUSION Through total endoscopic discectomy with the interlaminar approach,the degree of pain in the waist and leg was reduced,and the lumbar function considerably recovered.
