Skill Assessment of Copernicus Climate Change Service Seasonal Ensemble Precipitation Forecasts over Iran

Medium to long-term precipitation forecasting plays a pivotal role in water resource management and development of warning systems.Recently,the Copernicus Climate Change Service(C3S)database has been releasing monthly forecasts for lead times of up to three months for public use.This study evaluated the ensemble forecasts of three C3S models over the period 1993-2017 in Iran’s eight classified precipitation clusters for one-to three-month lead times.Probabilistic and non-probabilistic criteria were used for evaluation.Furthermore,the skill of selected models was analyzed in dry and wet periods in different precipitation clusters.The results indicated that the models performed best in western precipitation clusters,while in the northern humid cluster the models had negative skill scores.All models were better at forecasting upper-tercile events in dry seasons and lower-tercile events in wet seasons.Moreover,with increasing lead time,the forecast skill of the models worsened.In terms of forecasting in dry and wet years,the forecasts of the models were generally close to observations,albeit they underestimated several severe dry periods and overestimated a few wet periods.Moreover,the multi-model forecasts generated via multivariate regression of the forecasts of the three models yielded better results compared with those of individual models.In general,the ECMWF and UKMO models were found to be appropriate for one-month-ahead precipitation forecasting in most clusters of Iran.For the clusters considered in Iran and for the long-range system versions considered,the Météo France model had lower skill than the other models.

Global DEMs vary from one to another:an evaluation of newly released Copernicus,NASA and AW3D30 DEM on selected terrains of China using ICESat-2 altimetry data

A good understanding of the quality of digital elevation model(DEM)is a perquisite for various applications.This study investigates the accuracy of three most recently released 1-arcsec global DEMs(GDEMs,Copernicus,NASA and AW3D30)in five selected terrains of China,using more than 240,000 high-quality ICESat-2(Ice,Cloud and land Elevation Satellite)ALT08 points.The results indicate the three GDEMs have similar overall vertical accuracy,with RMSE of 6.73(Copernicus),6.59(NASA)and 6.63 m(AW3D30).While the accuracy varies considerably over study areas and among GDEMs.The results show a clear correlation between the accuracy and terrain slopes,and some relationship between the accuracy and land covers.Our analysis reveals the land cover exerts a greater impact on the accuracy than that of the terrain slope for the study area.Visual inspections of terrain representation indicate Copernicus DEM exhibits the greatest detail of terrain,followed by AW3D30,and then by NASADEM.This study has demonstrated that ICESat-2 altimetry offers an important tool for DEM assessment.The findings provide a timely and comprehensive understanding of the quality of newly released GDEMs,which are informative for the selection of suitable DEMs,and for the improvement of GDEM in future studies.

Comparative study of optic disc measurement by Copernicus optical coherence tomography and Heidelberg retinal tomography

Background Copernicus optical coherence tomography （SOCT） is a new, ultra high-speed and high-resolution instrument available for clinical evaluation of optic nerve. The purpose of the study was to compare the agreements between SOCT and Heidelberg retinal tomography （HRT）. Methods A total of 44 healthy normal volunteers were recruited in this study. One eye in each subject was selected randomly. Agreement between SOCT and HRT-3 in measuring optic disc area was assessed using Bland-Altman plots. Relationships between measurements of optic nerve head parameter obtained by SOCT and HRT-3 were assessed by Pearson correlation. Results There was no significant difference in the average cup area （0.306 vs. 0.355 mm, P=0.766）, cup volume （0.158 vs. 0.130 mm, P=0.106） and cup/disc ration （0.394 vs. 0.349 mm, P=0.576） measured by the two instruments. However, other optic disc parameters from SOCT were significantly lower compared with HRT-3. The Bland-Altman plot revealed good agreement of cup area and cup volume measured by SOCT and HRT-3. Bad agreement of disc area, rim area, rim volume and cup/disc ratio were found between SOCT and HRT-3. The highest correlations between the two instruments were observed for cup area （r2=0.783, P=0.000） and cup/disc ratio （r2=0.669, P=0.000）, whereas the lowest correlation was observed for disc area （r2=0.100, P=-0.037）, rim area （r2=0.275, P=0.000）, cup volume （r2=0.005, P=0.391） and rim volume （r2=0.021, P=0.346）. Conclusions There were poor agreements between SOCT and HRT-3 for measurement of optic nerve parameters except cup area and cup volume. Measurement results of the two instruments are not interchangeable.

Insights into CODE-DE–Germany’s Copernicus data and exploitation platform

This article presents and analyses the modular architecture and capabilities of CODE-DE(Copernicus Data and Exploitation Platform–Deutschland,www.code-de.org),the integrated German operational environment for accessing and processing Copernicus data and products,as well as the methodology to establish and operate the system.Since March 2017,CODE-DE has been online with access to Sentinel-1 and Sentinel-2 data,to Sentinel-3 data shortly after this time,and since March 2019 with access to Sentinel-5P data.These products are available and accessed by 1,682 registered users as of March 2019.During this period 654,895 products were downloaded and a global catalogue was continuously updated,featuring a data volume of 814 TByte based on a rolling archive concept supported by a reload mechanism from a long-term archive.Since November 2017,the element for big data processing has been operational,where registered users can process and analyse data themselves specifically assisted by methods for value-added product generation.Utilizing 195,467 core and 696,406 memory hours,982,948 products of different applications were fully automatically generated in the cloud environment and made available as of March 2019.Special features include an improved visualization of available Sentinel-2 products,which are presented within the catalogue client at full 10 m resolution.

突破禁区—走出β_1受体阻滞剂心力衰竭治疗屏障

β-受体阻滞剂(β-Receptor Blacker,β-RB)又称β-受体拮抗剂(β-Receptor Antagonist),其发展可追溯至20世纪70年代,首例药普萘洛尔(心得安)问世,在此后的几十年中进展迅速,药物品种已近百,在抗心绞痛、抗心律失常、高血压上显示了良效,其重要性已得到全球医药界的认可。但由于认识上的偏差,既往β-RB在治疗心力衰竭(HF)、心梗(AMI)上曾作为禁区,但近年来,多项大样本临床研究证实(CIBIS-Ⅱ、MERIT-HF、COPERNICUS等),β-RB长期治疗可改善慢性HF者的心脏功能、左室功能,提高射血分数,降低死亡率。成为当前治疗慢性HF、AMI的重要手段,公认首选药有选择性β-RB比索洛尔、美托洛尔和非选择性的卡维地洛、布新洛尔。但鉴于几十年的认识偏见,其在应用上仍存有误区和争论!如何突破禁区?走出β-RB应用上的偏见,逾越治疗屏障?在临床上得到多数医师的认可,扩大应用范围。本文旨在提出问题,期盼以带动心血管临床的关注和探讨。

卡维地洛前瞻随机累积生存试验简介

几个大规模临床试验已经确立了β阻断剂在治疗轻、中度心力衰竭中的地位,但这些研究尚不足以证明β阻断剂对重度心力衰竭(以下简称心衰)的疗效.卡维地洛兼有β1、β2及α1肾上腺素能受体阻断作用,认为可逆转心衰时交感神经激活的不良反应.

Mapping Lunar Olivine Using Clementine Spectral Indices and Chemical Composition Parameters

Olivine exposures at the central peak of Copernicus crater of the Earth＇s Moon have been confirmed by telescope observations and Clementine spectra data. Using these exposures as training sites, this study used a method of combining two spectral indices （950 nm/750 nm and 2000 nm/1500 nm）, one maturity index （Is/FeO）, and four chemical content indices （FeO, Mg, Al, Ca）, through a decision tree classifier, to map olivine-rich units on the west lunar surface based on mosaicked Clementine image （500 m pixel size）. Most classified olivine exposures are found inside craters or on their rays, suggesting that olivine exposures are directly associated with the impact processes. The results have been validated in several selected sites, though further validations with data from the newest missions are strongly needed.

《环境与职业医学》被英国CABI和波兰IC数据库分别收录

经英国《国际农业与生物科学研究中心》（Centre for Agriculture and Bioscience International，CABI）和波兰《哥白尼索引》（Index Copernicus，IC）专家组评估，《环境与职业医学》杂志符合CABI和IC数据库收录要求。因此，从2007年9月和11月起本刊正式被CABI和IC数据库收录为源期刊。

《华西口腔医学杂志》被波兰《哥白尼索引》收录

波兰《哥白尼索引》（index copernicus，IC）；是由Medieal Science International（国际医学）创办的医药学、生物学国际检索系统，是一个新的通向科学信息的世界性的门户，有益地补充了美国《医学索引》（Medline）和美国科学信息研究所（ISI）的内容。最近，《华西口腔医学杂志》被波兰《哥白尼索引》收录。

祝贺我刊被波兰《哥白尼索引》收录

2010年3月16日，我刊编辑部收到波兰《哥白尼索引》（Index Copernicus）数据库收录通知，本刊自2010年第1期开始作为其收录刊源。波兰《哥白尼索引》（Index Copernicus，简称IC）是由Medical Science International（国际医学）创办的医药学、

本刊征稿启事

《江苏大学学报（医学版）》是中国科技核心期刊（中国科技论文统计源期刊）、RCCSE中国核心学术期刊,并被美国《化学文摘》（chemical abstracts,CA）,《剑桥科学文摘》（cambridge scientific abstracts,CSA）,波兰《哥白尼索引》（index copernicus,IC）,中国科技论文与引文数据库（CSTPCD）,中文生物医学期刊文献数据库（CMCC）,中国学术期刊网全文数据库（CNKI）等数据库收录。