目的验证基于临床CT的数字体相关(digital volume correlation,DVC)方法在测量股骨内部变形场时的准确性,并通过DVC进一步测量股骨在跌倒情况下的内部变形,验证基于临床CT的有限元分析方法(finite element analysis,FEA)在计算股骨内部...目的验证基于临床CT的数字体相关(digital volume correlation,DVC)方法在测量股骨内部变形场时的准确性,并通过DVC进一步测量股骨在跌倒情况下的内部变形,验证基于临床CT的有限元分析方法(finite element analysis,FEA)在计算股骨内部变形场的准确性。方法使用猪股骨,模拟侧向跌倒姿态,进行分步力学加载实验,同步进行多次CT成像。通过重复扫描和虚拟位移验证DVC方法的准确性。DVC以子体积作为配准两组图像的研究对象,分别设置8、12、16和20 mm的子体积进行测试。量化误差指标包括位移系统误差-平均值(mean)、位移随机误差-标准差(standard deviation,SD)、应变准确度-平均绝对误差(mean absolute error,MAER)和应变精确度-标准差误差(standard deviation of the error,SDER)。基于CT图像建立股骨有限元模型,模拟实验条件,计算股骨内部位移,与DVC测量的内部变形场对比验证。结果基于临床CT的DVC方法重复扫描位移偏差小于0.013 mm,MAER和SDER均小于200με;虚拟位移偏差小于0.098 mm,MAER为1093~1687με,SDER为604~1267με,远小于骨组织屈服应变。FEA计算的位移和DVC测量的位移之间具有较强的相关性(R^(2)≥0.76,P<0.05)。结论基于临床CT的DVC方法可以准确测量股骨内部变形场,并且基于临床CT的有限元模型可以准确计算股骨内部变形场。展开更多
Objective:To evaluate the correlation of the quantifiable parameters of blood flow pattern derived with dynamic CT in solitary bronchogenic adenocarcinoma(SBA).Methods:46 patients with solitary bronchogenic adenocarci...Objective:To evaluate the correlation of the quantifiable parameters of blood flow pattern derived with dynamic CT in solitary bronchogenic adenocarcinoma(SBA).Methods:46 patients with solitary bronchogenic adenocarcinomas (SBA)(diameter≤4 cm)underwent multi-location dynamic contrast material-enhanced(nonionic contrast material was administrated via the antecubital vein at a rate of 4 mL/s by using an autoinjector 90 mL,4×5 mm or 4×2.5 mm scanning mode with stable table were performed)serial CT.Precontrast and postcontrast attenuation on every scan was recorded.Perfusion (PBA),peak height(PHBA),ratio of peak height of the SPN to that of the aorta(BA-to-A ratio)and mean transit time(MTT)were calculated.The correlation between peak height of the aorta(PHA)and parameters of the SBA(PHBA,BA-to-A ratio,PBA,and MTT)and those among parameters of the SBA were assessed by means of linear regression analysis.Regression equation among parameters of the SBA were obtain by means of stepwise regression.Results:The correlation between the SBA peak height(PHBA,36.78 HU±12.02)and the aortic peak height(PHA)was significant(r=0.506,P<0.0001).No significant cor- relation was found between the BA-to-Apeak height ratio(15.33%±4.55)and the aortic peak height(r=0.130,P=0.388> 0.05)as it was between the SBA perfusion(PBA,31.86 mL/min/100 g±9.74)and the aortic peak height(r=0.049,P=0.749 >0.05).The SBA perfusion correlated with the PHBA and the BA-to-A peak height ratio(r=0.394,P=0.007<0.05;r=0.407, P=0.005<0.05).The PHBA correlated positively with the BA-to-A peak height ratio(r=0.781,P<0.0001).Mean transit time was 14.84 s±5.52.PBA=18.500+0.872×BA-to-A ratio.BA-to-A ratio=4.467+0.295×PHBA.Conclusion:The linear correlation between the SBA perfusion and BA-to-Aratio and that between BA-to-Aratio and PHBA can be expressed by equation. It is possible to design a simpler scanning procedure of investigation of bronchogenic adenocarcinoma angiogenesis.展开更多
Aim of the Study: Aim of this study is to evaluate the patients of biopsy proven esophageal carcinoma with Contrast CT studies (CECT thorax, abdomen or neck), correlate and compare the CT findings with esophagographic...Aim of the Study: Aim of this study is to evaluate the patients of biopsy proven esophageal carcinoma with Contrast CT studies (CECT thorax, abdomen or neck), correlate and compare the CT findings with esophagographic findings in each case and with biopsy findings wherever possible. Materials and Methods: Fifty (50) biopsy proven cases of esophageal carcinoma were taken into study in Radiology Department of Govt. Medical College, Patiala, Punjab after informed consents. All the patients underwent esophagography with barium sulphate as the contrast material and contrast enhanced CT scan of neck and/or thorax and/or abdomen. In all cases, esophagographic study preceded the CT scan. The time gap between the two studies was kept to the minimum to make the studies comparable. Results: The CT findings were found to have significant correlation with the esophagographic findings (p value > 0.05 in each finding) in regard to luminal narrowing, proximal dilatation and hold up of contrast, eccentricity of growth, site involved, length of growth, involvement of pyriform sinuses/valeculla and involvement of GE junction. Conclusions: CT study primarily helps to rule out unresectable or distant metastatic disease. Barium studies cannot provide any information regarding local invasion into mediastinal structures, regional or non-regional lymphadenopathy or metastases to distant organs which are significant for determining the treatment modality. CT has an advantage over esophagography for these information.展开更多
Over the past few years, with the development of molecular biology and immunology, research concerning carcinoma antigens has advanced rapidly. At the same time, the application of spiral CT for imaging diagnosis also...Over the past few years, with the development of molecular biology and immunology, research concerning carcinoma antigens has advanced rapidly. At the same time, the application of spiral CT for imaging diagnosis also has achieved excellent success. Many scholars have conducted studies on the correlation between the expression of tumor antigens and CT imaging. This report is a summary of these studies.展开更多
文摘目的验证基于临床CT的数字体相关(digital volume correlation,DVC)方法在测量股骨内部变形场时的准确性,并通过DVC进一步测量股骨在跌倒情况下的内部变形,验证基于临床CT的有限元分析方法(finite element analysis,FEA)在计算股骨内部变形场的准确性。方法使用猪股骨,模拟侧向跌倒姿态,进行分步力学加载实验,同步进行多次CT成像。通过重复扫描和虚拟位移验证DVC方法的准确性。DVC以子体积作为配准两组图像的研究对象,分别设置8、12、16和20 mm的子体积进行测试。量化误差指标包括位移系统误差-平均值(mean)、位移随机误差-标准差(standard deviation,SD)、应变准确度-平均绝对误差(mean absolute error,MAER)和应变精确度-标准差误差(standard deviation of the error,SDER)。基于CT图像建立股骨有限元模型,模拟实验条件,计算股骨内部位移,与DVC测量的内部变形场对比验证。结果基于临床CT的DVC方法重复扫描位移偏差小于0.013 mm,MAER和SDER均小于200με;虚拟位移偏差小于0.098 mm,MAER为1093~1687με,SDER为604~1267με,远小于骨组织屈服应变。FEA计算的位移和DVC测量的位移之间具有较强的相关性(R^(2)≥0.76,P<0.05)。结论基于临床CT的DVC方法可以准确测量股骨内部变形场,并且基于临床CT的有限元模型可以准确计算股骨内部变形场。
文摘Objective:To evaluate the correlation of the quantifiable parameters of blood flow pattern derived with dynamic CT in solitary bronchogenic adenocarcinoma(SBA).Methods:46 patients with solitary bronchogenic adenocarcinomas (SBA)(diameter≤4 cm)underwent multi-location dynamic contrast material-enhanced(nonionic contrast material was administrated via the antecubital vein at a rate of 4 mL/s by using an autoinjector 90 mL,4×5 mm or 4×2.5 mm scanning mode with stable table were performed)serial CT.Precontrast and postcontrast attenuation on every scan was recorded.Perfusion (PBA),peak height(PHBA),ratio of peak height of the SPN to that of the aorta(BA-to-A ratio)and mean transit time(MTT)were calculated.The correlation between peak height of the aorta(PHA)and parameters of the SBA(PHBA,BA-to-A ratio,PBA,and MTT)and those among parameters of the SBA were assessed by means of linear regression analysis.Regression equation among parameters of the SBA were obtain by means of stepwise regression.Results:The correlation between the SBA peak height(PHBA,36.78 HU±12.02)and the aortic peak height(PHA)was significant(r=0.506,P<0.0001).No significant cor- relation was found between the BA-to-Apeak height ratio(15.33%±4.55)and the aortic peak height(r=0.130,P=0.388> 0.05)as it was between the SBA perfusion(PBA,31.86 mL/min/100 g±9.74)and the aortic peak height(r=0.049,P=0.749 >0.05).The SBA perfusion correlated with the PHBA and the BA-to-A peak height ratio(r=0.394,P=0.007<0.05;r=0.407, P=0.005<0.05).The PHBA correlated positively with the BA-to-A peak height ratio(r=0.781,P<0.0001).Mean transit time was 14.84 s±5.52.PBA=18.500+0.872×BA-to-A ratio.BA-to-A ratio=4.467+0.295×PHBA.Conclusion:The linear correlation between the SBA perfusion and BA-to-Aratio and that between BA-to-Aratio and PHBA can be expressed by equation. It is possible to design a simpler scanning procedure of investigation of bronchogenic adenocarcinoma angiogenesis.
文摘Aim of the Study: Aim of this study is to evaluate the patients of biopsy proven esophageal carcinoma with Contrast CT studies (CECT thorax, abdomen or neck), correlate and compare the CT findings with esophagographic findings in each case and with biopsy findings wherever possible. Materials and Methods: Fifty (50) biopsy proven cases of esophageal carcinoma were taken into study in Radiology Department of Govt. Medical College, Patiala, Punjab after informed consents. All the patients underwent esophagography with barium sulphate as the contrast material and contrast enhanced CT scan of neck and/or thorax and/or abdomen. In all cases, esophagographic study preceded the CT scan. The time gap between the two studies was kept to the minimum to make the studies comparable. Results: The CT findings were found to have significant correlation with the esophagographic findings (p value > 0.05 in each finding) in regard to luminal narrowing, proximal dilatation and hold up of contrast, eccentricity of growth, site involved, length of growth, involvement of pyriform sinuses/valeculla and involvement of GE junction. Conclusions: CT study primarily helps to rule out unresectable or distant metastatic disease. Barium studies cannot provide any information regarding local invasion into mediastinal structures, regional or non-regional lymphadenopathy or metastases to distant organs which are significant for determining the treatment modality. CT has an advantage over esophagography for these information.
文摘Over the past few years, with the development of molecular biology and immunology, research concerning carcinoma antigens has advanced rapidly. At the same time, the application of spiral CT for imaging diagnosis also has achieved excellent success. Many scholars have conducted studies on the correlation between the expression of tumor antigens and CT imaging. This report is a summary of these studies.
