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Performance and Application of Double-layered Microcapsule Corrosion Inhibitors
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作者 余海燕 WANG Yingxiang +2 位作者 WANG Ruizhi HU Lintong WANG Tianlei 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2024年第4期845-853,共9页
Double-layered microcapsule corrosion inhibitors were developed by sodium monofluorophosphate as the core material,polymethyl methacrylate as the inner wall material,and polyvinyl alcohol as the outer wall material co... Double-layered microcapsule corrosion inhibitors were developed by sodium monofluorophosphate as the core material,polymethyl methacrylate as the inner wall material,and polyvinyl alcohol as the outer wall material combining the solvent evaporation method and spray drying method.The protection by the outer capsule wall was used to prolong the service life of the corrosion inhibitor.The dispersion,encapsulation,thermal stability of microcapsules,and the degradation rate of capsule wall in concrete pore solution were analyzed by ultra-deep field microscopy,scanning electron microscopy,thermal analyzer,and sodium ion release rate analysis.The microcapsules were incorporated into mortar samples containing steel reinforcement,and the effects of double-layered microcapsule corrosion inhibitors on the performance of the cement matrix and the actual corrosion-inhibiting effect were analyzed.The experimental results show that the double-layered microcapsules have a moderate particle size and uniform distribution,and the capsules were completely wrapped.The microcapsules as a whole have good thermal stability below 230 ℃.The monolayer membrane structure microcapsules completely broke within 1 day in the simulated concrete pore solution,and the double-layer membrane structure prolonged the service life of the microcapsules to 80 days in the simulated concrete pore solution before the core material was completely released.The mortar samples containing steel reinforcement incorporated with the double-layered microcapsule corrosion inhibitors still maintained a higher corrosion potential than the monolayer microcapsule corrosion inhibitors control group at 60 days.The incorporation of double-layered microcapsules into the cement matrix has no significant adverse effect on the setting time and early strength. 展开更多
关键词 corrosion inhibitors MICROCAPSULE double-layer structure potentiodynamic polarization curve
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Advancements in enhancing corrosion protection of Mg alloys:A comprehensive review on the synergistic effects of combining inhibitors with PEO coating
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作者 Arash Fattah-alhosseini Abdelhameed Fardosi +1 位作者 Minoo Karbasi Mosab Kaseem 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第2期465-489,共25页
Magnesium(Mg)alloys are lightweight materials with excellent mechanical properties,making them attractive for various applications,including aerospace,automotive,and biomedical industries.However,the practical applica... Magnesium(Mg)alloys are lightweight materials with excellent mechanical properties,making them attractive for various applications,including aerospace,automotive,and biomedical industries.However,the practical application of Mg alloys is limited due to their high susceptibility to corrosion.Plasma electrolytic oxidation(PEO),or micro-arc oxidation(MAO),is a coating method that boosts Mg alloys'corrosion resistance.However,despite the benefits of PEO coatings,they can still exhibit certain limitations,such as failing to maintain long-term protection as a result of their inherent porosity.To address these challenges,researchers have suggested the use of inhibitors in combination with PEO coatings on Mg alloys.Inhibitors are chemical compounds that can be incorporated into the coating or applied as a post-treatment to further boost the corrosion resistance of the PEO-coated Mg alloys.Corrosion inhibitors,whether organic or inorganic,can act by forming a protective barrier,hindering the corrosion process,or modifying the surface properties to reduce susceptibility to corrosion.Containers can be made of various materials,including polyelectrolyte shells,layered double hydroxides,polymer shells,and mesoporous inorganic materials.Encapsulating corrosion inhibitors in containers fully compatible with the coating matrix and substrate is a promising approach for their incorporation.Laboratory studies of the combination of inhibitors with PEO coatings on Mg alloys have shown promising results,demonstrating significant corrosion mitigation,extending the service life of Mg alloy components in aggressive environments,and providing self-healing properties.In general,this review presents available information on the incorporation of inhibitors with PEO coatings,which can lead to improved performance of Mg alloy components in demanding environments. 展开更多
关键词 inhibitor Mg alloy Self-healing coating Plasma electrolytic oxidation(PEO) corrosion protection
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Electrochemical Study of the Corrosion Inhibitory Capacity of Calcined Attapulgite in Reinforced Concrete Medium
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作者 Malang Bodian Kinda Hannawi +3 位作者 Dame Keinde Modou Fall Aveline Darquennes Prince William Agbodjan 《Advances in Materials Physics and Chemistry》 CAS 2024年第5期76-94,共19页
The durability of reinforced concrete structures is greatly influenced by the corrosion of the reinforcement. In addition to air pollution related to the repair of corroded structures, chloride ions are the main facto... The durability of reinforced concrete structures is greatly influenced by the corrosion of the reinforcement. In addition to air pollution related to the repair of corroded structures, chloride ions are the main factors of corrosion of reinforced concrete structures. This study aims to valorize a clay inhibitor against reinforcement corrosion in reinforced concrete. This clay (Attapulgite) was incorporated into reinforced concretes at different percentages of substitution of calcined attapulgite (0%, 5% and 10%) to cement in the formulation. The corrosion inhibitory power of attapulgite is evaluated in reinforced concretes subjected to the action of chloride ions at different intervals in the NaCl solution (1 day, 21 days and 45 days) by electrochemical methods (zero current chronopotentiometry, polarization curves and electrochemical impedance spectroscopy). This study showed that in the presence of chloride ions, the composition based on 10% attapulgite has an appreciable inhibitory effect with an average inhibitory efficiency of 82%. 展开更多
关键词 ATTAPULGITE Electrochemical Methods inhibitor Reinforced Concrete
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Evaluation of the Inhibitory Gel Aloe vera against Corrosion of Reinforcement Concrete in NaCl Medium
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作者 Malang Bodian Dame Keinde +3 位作者 Kinda Hannawi Modou Fall Aveline Darquennes Prince William Agbodjan 《Materials Sciences and Applications》 2024年第5期101-112,共12页
Most reinforced concrete structures in seaside locations suffer from corrosion damage to the reinforcement, limiting their durability and necessitating costly repairs. To improve their performance and durability, we h... Most reinforced concrete structures in seaside locations suffer from corrosion damage to the reinforcement, limiting their durability and necessitating costly repairs. To improve their performance and durability, we have investigated in this paper Aloe vera extracts as a green corrosion inhibitor for reinforcing steel in NaCl environments. Using electrochemical methods (zero-intensity chronopotentiometry, Tafel lines and electrochemical impedance spectroscopy), this experimental work investigated the effect of these Aloe vera (AV) extracts on corrosion inhibition of concrete reinforcing bar (HA, diameter 12mm) immersed in a 0.5M NaCl solution. The results show that Aloe vera extracts have an average corrosion-inhibiting efficacy of around 86% at an optimum concentration of 20%. 展开更多
关键词 Reinforced Concrete Green inhibitor corrosion REINFORCEMENT Electrochemical Methods
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Experiment and numerical simulation of distribution law of waterbased corrosion inhibitor in natural gas gathering and transportation pipeline
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作者 En-Bin Liu Hao Tang +4 位作者 Yin-Hui Zhang Dang-jian Li Bo Kou Ning Liu Mohammadamin Azimi 《Petroleum Science》 SCIE EI CAS CSCD 2023年第3期1857-1873,共17页
The transmission medium of natural gas gathering and transportation pipelines usually contains cor-rosive gases,which will cause serious corrosion on the inner wall of the pipelines when they coexist with water.Theref... The transmission medium of natural gas gathering and transportation pipelines usually contains cor-rosive gases,which will cause serious corrosion on the inner wall of the pipelines when they coexist with water.Therefore,it is necessary to add corrosion inhibitor to form a protective film to protect the pipeline.The distribution of corrosion inhibitors in a gathering and transportation pipeline in Moxi gas field was studied by combining experiment and simulation.The Pearson function was used to calculate the experimental and simulation results,and the correlation was more than 80%,indicating a high degree of agreement.The simulation results show that:①The larger the pipe angle,filling speed and gas flow rate,the smaller the particle size,the better the distribution of corrosion inhibitor particles in the pipe.The filling amount will affect the concentration,but the distribution trend is unchanged;②A method to determine the filling mode based on the loss was proposed,and for this pipeline,the loss of corrosion inhibitor was determined to be 5.31×10^(-3) kg/s,and the flling amount was recommended to be adjusted to 2o L/h,which has certain guiding significance for the actual flling strategy of pipeline corrosion inhibitor. 展开更多
关键词 corrosion inhibitor corrosion Computational fluid dynamics ELECTROCHEMISTRY Droplet distribution
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Prevention of Q235 Steel Corrosion using Waterborne Rust Inhibitor
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作者 闫镇威 KANG Mingjie +3 位作者 谭兆钧 李全德 田宝强 李帅 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS CSCD 2023年第1期206-211,共6页
Sorbitol,triethanolamine,sodium benzoate,boric acid,and sodium carbonate were mixed to prepare a waterborne rust inhibitor.A temperature and humidity accelerated corrosion test was applied to investigate the corrosion... Sorbitol,triethanolamine,sodium benzoate,boric acid,and sodium carbonate were mixed to prepare a waterborne rust inhibitor.A temperature and humidity accelerated corrosion test was applied to investigate the corrosion behaviour of waterborne rust inhibitor coated Q235 steel and original Q235 steel,which was carried out in a temperature and humidity test chamber(WSHW-1000)at a temperature of 80℃and humidity of 95%.Compared with the original Q235,waterborne rust inhibitor coated Q235 has better resistance to corrosion in hot and humid ambient conditions.Electrochemical impedance spectroscopy and potentiodynamic polarization were measured with a three-electrode cell in 3.5%NaCl aqueous solution on a CHI760E potentiostat/galvanostat.Molecular dynamics was simulated to verify the synergistic corrosion inhibitory mechanism of sodium carbonate and triethanolamine.The test shows that the prepared waterborne rust inhibitor can reduce the tendency of Q235 to corrosion and can also effectively reduce the corrosion rate. 展开更多
关键词 Q235 steel waterborne rust inhibitor temperature and humidity test electrochemical corrosion
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Prediction model for corrosion rate of low-alloy steels under atmospheric conditions using machine learning algorithms 被引量:1
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作者 Jingou Kuang Zhilin Long 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2024年第2期337-350,共14页
This work constructed a machine learning(ML)model to predict the atmospheric corrosion rate of low-alloy steels(LAS).The material properties of LAS,environmental factors,and exposure time were used as the input,while ... This work constructed a machine learning(ML)model to predict the atmospheric corrosion rate of low-alloy steels(LAS).The material properties of LAS,environmental factors,and exposure time were used as the input,while the corrosion rate as the output.6 dif-ferent ML algorithms were used to construct the proposed model.Through optimization and filtering,the eXtreme gradient boosting(XG-Boost)model exhibited good corrosion rate prediction accuracy.The features of material properties were then transformed into atomic and physical features using the proposed property transformation approach,and the dominant descriptors that affected the corrosion rate were filtered using the recursive feature elimination(RFE)as well as XGBoost methods.The established ML models exhibited better predic-tion performance and generalization ability via property transformation descriptors.In addition,the SHapley additive exPlanations(SHAP)method was applied to analyze the relationship between the descriptors and corrosion rate.The results showed that the property transformation model could effectively help with analyzing the corrosion behavior,thereby significantly improving the generalization ability of corrosion rate prediction models. 展开更多
关键词 machine learning low-alloy steel atmospheric corrosion prediction corrosion rate feature fusion
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New insights on the high-corrosion resistance of UHP Mg-Ge alloys tested in a simulated physiological environment 被引量:1
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作者 Ting Liu Xingrui Chen +4 位作者 Jeffrey Venezuela Yuan Wang Zhiming Shi Wenyi Chen Matthew Dargusch 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第3期1026-1044,共19页
UHP Mg-Ge alloys was recently found to provide excellent corrosion resistance.This paper provides new insights on the mechanism of improved corrosion resistance of UHP Mg-Ge alloys in Hanks’solution.The studied UHP M... UHP Mg-Ge alloys was recently found to provide excellent corrosion resistance.This paper provides new insights on the mechanism of improved corrosion resistance of UHP Mg-Ge alloys in Hanks’solution.The studied UHP Mg-0.5Ge and UHP Mg-1Ge alloys showed superior corrosion resistance compared to UHP Mg and WE43,with the Mg-1Ge exhibiting the best corrosion performance.The exceptional corrosion resistance of the UHP alloy is attributed to(i)Mg_(2)Ge’s ability to suppress cathodic kinetics,(ii)Ge’s capability to accelerate the formation of a highly passive layer,and the(iii)low amounts of corrosion-accelerating impurities. 展开更多
关键词 UHP Mg-Ge alloy Cathodic kinetics suppression Biodegradable metals In vitro corrosion Magnesium corrosion.
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In-situ construction of grass-like hybrid architecture responsible for extraordinary corrosion performance: Experimental and theoretical approach
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作者 T.Suhartono F.Hazmatulhaq +3 位作者 Y.Sheng A.Chaouiki M.P.Kamil Y.G.Ko 《Nano Materials Science》 EI CAS CSCD 2024年第1期44-59,共16页
Despite the engineering potential by the co-existence of inorganic and organic substances to protect vulnerable metallic materials from corrosive environments,both their interaction and in-situ formation mechanism to ... Despite the engineering potential by the co-existence of inorganic and organic substances to protect vulnerable metallic materials from corrosive environments,both their interaction and in-situ formation mechanism to induce the nature-inspired composite remained less understood.The present work used three distinctive mercaptobenzazole(MB)compounds working as corrosion inhibitors,such as 2-mercaptobenzoxazole(MBO),2-mercaptobenzothiazole(MBT),and 2-mercaptobenzimidazole(MBI)in a bid to understand how the geometrical structure arising from O,S,and N atoms affected the interaction toward inorganic layer.MB compounds that were used here to control the corrosion kinetics would be interacted readily with the pre-existing MgO layer fabricated by plasma electrolysis.This phenomenon triggered the nucleation of the root network since MB compounds were seen to be adsorbed actively on the defective surface through the active sites in MB compound.Then,the molecule with twin donor atoms adjacent to the mercapto-sites affected the facile growth of the grass-like structures with‘uniform’distribution via molecular self-assembly,which showed better corrosion performance than those with having dissimilar donor atoms with the inhibition efficiency(η)of 97%approximately.The formation mechanism underlying nucleation and growth behavior of MB molecule was discussed concerning the theoretical calculation of density functional theory. 展开更多
关键词 Nature-inspired composite Organic-inorganic interaction corrosion inhibitor Density functional theory ELECTROCHEMISTRY
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High corrosion and wear resistant electroless Ni–P gradient coatings on aviation aluminum alloy parts 被引量:1
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作者 Bo Wang Jiawei Li +2 位作者 Zhihui Xie Gengjie Wang Gang Yu 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CSCD 2024年第1期155-164,共10页
A Ni–P alloy gradient coating consisting of multiple electroless Ni–P layers with various phosphorus contents was prepared on the aviation aluminum alloy. Several characterization and electrochemical techniques were... A Ni–P alloy gradient coating consisting of multiple electroless Ni–P layers with various phosphorus contents was prepared on the aviation aluminum alloy. Several characterization and electrochemical techniques were used to characterize the different Ni–P coatings’ morphologies, phase structures, elemental compositions, and corrosion protection. The gradient coating showed good adhesion and high corrosion and wear resistance, enabling the application of aluminum alloy in harsh environments. The results showed that the double zinc immersion was vital in obtaining excellent adhesion (81.2 N). The optimal coating was not peeled and shredded even after bending tests with angles higher than 90°and was not corroded visually after 500 h of neutral salt spray test at 35℃. The high corrosion resistance was attributed to the misaligning of these micro defects in the three different nickel alloy layers and the amorphous structure of the high P content in the outer layer. These findings guide the exploration of functional gradient coatings that meet the high application requirement of aluminum alloy parts in complicated and harsh aviation environments. 展开更多
关键词 aluminum alloy ELECTROLESS nickel coating corrosion ADHESION
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Prediction models of burst strength degradation for casing with considerations of both wear and corrosion 被引量:1
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作者 Jie-Li Wang Wen-Jun Huang De-Li Gao 《Petroleum Science》 SCIE EI CAS CSCD 2024年第1期458-474,共17页
Casing wear and casing corrosion are serious problems affecting casing integrity failure in deep and ultra-deep wells.This paper aims to predict the casing burst strength with considerations of both wear and corrosion... Casing wear and casing corrosion are serious problems affecting casing integrity failure in deep and ultra-deep wells.This paper aims to predict the casing burst strength with considerations of both wear and corrosion.Firstly,the crescent wear shape is simplified into three categories according to common mathematical models.Then,based on the mechano-electrochemical(M-E)interaction,the prediction model of corrosion depth is built with worn depth as the initial condition,and the prediction models of burst strength of the worn casing and corroded casing are obtained.Secondly,the accuracy of different prediction models is validated by numerical simulation,and the main influence factors on casing strength are obtained.At last,the theoretical models are applied to an ultra-deep well in Northwest China,and the dangerous well sections caused by wear and corrosion are predicted,and the corrosion rate threshold to ensure the safety of casing is obtained.The results show that the existence of wear defects results in a stress concentration and enhanced M-E interaction on corrosion depth growth.The accuracy of different mathematical models is different:the slot ring model is most accurate for predicting corrosion depth,and the eccentric model is most accurate for predicting the burst strength of corroded casing.The burst strength of the casing will be overestimated by more than one-third if the M-E interaction is neglected,so the coupling effect of wear and corrosion should be sufficiently considered in casing integrity evaluation. 展开更多
关键词 Deep well Casing integrity Casing wear Casing corrosion Burst strength
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High-throughput calculations combining machine learning to investigate the corrosion properties of binary Mg alloys 被引量:1
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作者 Yaowei Wang Tian Xie +4 位作者 Qingli Tang Mingxu Wang Tao Ying Hong Zhu Xiaoqin Zeng 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第4期1406-1418,共13页
Magnesium(Mg)alloys have shown great prospects as both structural and biomedical materials,while poor corrosion resistance limits their further application.In this work,to avoid the time-consuming and laborious experi... Magnesium(Mg)alloys have shown great prospects as both structural and biomedical materials,while poor corrosion resistance limits their further application.In this work,to avoid the time-consuming and laborious experiment trial,a high-throughput computational strategy based on first-principles calculations is designed for screening corrosion-resistant binary Mg alloy with intermetallics,from both the thermodynamic and kinetic perspectives.The stable binary Mg intermetallics with low equilibrium potential difference with respect to the Mg matrix are firstly identified.Then,the hydrogen adsorption energies on the surfaces of these Mg intermetallics are calculated,and the corrosion exchange current density is further calculated by a hydrogen evolution reaction(HER)kinetic model.Several intermetallics,e.g.Y_(3)Mg,Y_(2)Mg and La_(5)Mg,are identified to be promising intermetallics which might effectively hinder the cathodic HER.Furthermore,machine learning(ML)models are developed to predict Mg intermetallics with proper hydrogen adsorption energy employing work function(W_(f))and weighted first ionization energy(WFIE).The generalization of the ML models is tested on five new binary Mg intermetallics with the average root mean square error(RMSE)of 0.11 eV.This study not only predicts some promising binary Mg intermetallics which may suppress the galvanic corrosion,but also provides a high-throughput screening strategy and ML models for the design of corrosion-resistant alloy,which can be extended to ternary Mg alloys or other alloy systems. 展开更多
关键词 Mg intermetallics corrosion property HIGH-THROUGHPUT Density functional theory Machine learning
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Risk of hepatitis B virus reactivation in oncological patients treated with tyrosine kinase inhibitors:A case report and literature analysis 被引量:1
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作者 Francesca Colapietro Nicola Pugliese +2 位作者 Antonio Voza Alessio Aghemo Stella De Nicola 《World Journal of Gastroenterology》 SCIE CAS 2024年第9期1253-1256,共4页
Hepatitis B virus(HBV)reactivation(HBVr)represents a severe and potentially life-threatening condition,and preventive measures are available through blood test screening or prophylactic therapy administration.The asse... Hepatitis B virus(HBV)reactivation(HBVr)represents a severe and potentially life-threatening condition,and preventive measures are available through blood test screening or prophylactic therapy administration.The assessment of HBVr traditionally considers factors such as HBV profile,including hepatitis B surface antigen(HBsAg)and antibody to hepatitis B core antigen,along with type of medication(chemotherapy;immunomodulants).Nevertheless,consideration of possible patient’s underlying tumor and the specific malignancy type(solid or hematologic)plays a crucial role and needs to be assessed for decision-making process. 展开更多
关键词 Chronic hepatitis B REACTIVATION Nucleoside analogue Tyrosine kinase inhibitors Onco-hematology
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Greatly enhanced corrosion/wear resistances of epoxy coating for Mg alloy through a synergistic effect between functionalized graphene and insulated blocking layer 被引量:1
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作者 Z.Y.Xue X.J.Li +3 位作者 J.H.Chu M.M.Li D.N.Zou L.B.Tong 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第1期332-344,共13页
The poor corrosion and wear resistances of Mg alloys seriously limit their potential applications in various industries.The conventional epoxy coating easily forms many intrinsic defects during the solidification proc... The poor corrosion and wear resistances of Mg alloys seriously limit their potential applications in various industries.The conventional epoxy coating easily forms many intrinsic defects during the solidification process,which cannot provide sufficient protection.In the current study,we design a double-layer epoxy composite coating on Mg alloy with enhanced anti-corrosion/wear properties,via the spin-assisted assembly technique.The outer layer is functionalized graphene(FG)in waterborne epoxy resin(WEP)and the inner layer is Ce-based conversion(Ce)film.The FG sheets can be homogeneously dispersed within the epoxy matrix to fill the intrinsic defects and improve the barrier capability.The Ce film connects the outer layer with the substrate,showing the transition effect.The corrosion rate of Ce/WEP/FG composite coating is 2131 times lower than that of bare Mg alloy,and the wear rate is decreased by~90%.The improved corrosion resistance is attributed to the labyrinth effect(hindering the penetration of corrosive medium)and the obstruction of galvanic coupling behavior.The synergistic effect derived from the FG sheet and blocking layer exhibits great potential in realizing the improvement of multi-functional integration,which will open up a new avenue for the development of novel composite protection coatings of Mg alloys. 展开更多
关键词 Mg alloy Functionalized graphene Epoxy coating corrosion/wear resistance Blocking layer
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Hepatic arterial infusion chemotherapy with anti-angiogenesis agents and immune checkpoint inhibitors for unresectable hepatocellular carcinoma and meta-analysis 被引量:1
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作者 Yu-Zhe Cao Guang-Lei Zheng +4 位作者 Tian-Qi Zhang Hong-Yan Shao Jia-Yu Pan Zi-Lin Huang Meng-Xuan Zuo 《World Journal of Gastroenterology》 SCIE CAS 2024年第4期318-331,共14页
BACKGROUND Hepatic arterial infusion chemotherapy(HAIC)has been proven to be an ideal choice for treating unresectable hepatocellular carcinoma(uHCC).HAIC-based treatment showed great potential for treating uHCC.Howev... BACKGROUND Hepatic arterial infusion chemotherapy(HAIC)has been proven to be an ideal choice for treating unresectable hepatocellular carcinoma(uHCC).HAIC-based treatment showed great potential for treating uHCC.However,large-scale studies on HAIC-based treatments and meta-analyses of first-line treatments for uHCC are lacking.AIM To investigate better first-line treatment options for uHCC and to assess the safety and efficacy of HAIC combined with angiogenesis inhibitors,programmed cell death of protein 1(PD-1)and its ligand(PD-L1)blockers(triple therapy)under real-world conditions.METHODS Several electronic databases were searched to identify eligible randomized controlled trials for this meta-analysis.Study-level pooled analyses of hazard ratios(HRs)and odds ratios(ORs)were performed.This was a retrospective single-center study involving 442 patients with uHCC who received triple therapy or angiogenesis inhibitors plus PD-1/PD-L1 blockades(AIPB)at Sun Yat-sen University Cancer Center from January 2018 to April 2023.Propensity score matching(PSM)was performed to balance the bias between the groups.The Kaplan-Meier method and cox regression were used to analyse the survival data,and the log-rank test was used to compare the suvival time between the groups.RESULTS A total of 13 randomized controlled trials were included.HAIC alone and in combination with sorafenib were found to be effective treatments(P values for ORs:HAIC,0.95;for HRs:HAIC+sorafenib,0.04).After PSM,176 HCC patients were included in the analysis.The triple therapy group(n=88)had a longer median overall survival than the AIPB group(n=88)(31.6 months vs 14.6 months,P<0.001)and a greater incidence of adverse events(94.3%vs 75.4%,P<0.001).CONCLUSION This meta-analysis suggests that HAIC-based treatments are likely to be the best choice for uHCC.Our findings confirm that triple therapy is more effective for uHCC patients than AIPB. 展开更多
关键词 Unresectable hepatocellular carcinoma Hepatic arterial infusion chemotherapy Angiogenesis inhibitors Programmed cell death protein 1 Programmed death ligand 1
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Sodium dodecyl sulfate (SDS) as an effective corrosion inhibitor for Mg-8Li-3Al alloy in aqueous NaCl: A combined experimental and theoretical investigation
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作者 Honggun Song Zhidong Xu +6 位作者 Lahouari Benabou Zheng Yin Hongyu Guan Hong Yan Luo Chao Zhi Hu Xudong Wang 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2023年第1期287-300,共14页
The corrosion inhibition behavior of Mg-8Li-3Al alloy in NaCl solution with sodium dodecyl sulfate(SDS)was investigated by hydrogen analysis,scanning electron microscopy(SEM),electrochemical test,scanning Kelvin probe... The corrosion inhibition behavior of Mg-8Li-3Al alloy in NaCl solution with sodium dodecyl sulfate(SDS)was investigated by hydrogen analysis,scanning electron microscopy(SEM),electrochemical test,scanning Kelvin probe force microscopy(SKPFM)and computational methods.Results showed that the corrosion resistance of Mg-8Li-3Al alloy in NaCl solution was effectively improved with SDS.The SEM and SKPFM results confirmed a dense,200 nm-thick SDS-adsorbed layer had formed on the alloy surface.The separation energy ΔE_(gap) and adsorption energy E_(ads) of SDS on the Mg surface were calculated by density functional theory and molecular dynamics simulations,respectively.And the corrosion inhibition mechanism was hypothesized and described. 展开更多
关键词 Mg-Li alloy corrosion Sodium dodecyl sulfate Scanning kelvin probe force microscopy Density functional theory Molecular dynamics
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Comparative efficacy of sodium glucose cotransporter-2 inhibitors in the management of type 2 diabetes mellitus:A real-world experience 被引量:1
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作者 Lubna Islam Dhanya Jose +3 位作者 Mohammed Alkhalifah Dania Blaibel Vishnu Chandrabalan Joseph M Pappachan 《World Journal of Diabetes》 SCIE 2024年第3期463-474,共12页
BACKGROUND Sodium glucose cotransporter-2 inhibitors(SGLT-2i)are a class of drugs with modest antidiabetic efficacy,weight loss effect,and cardiovascular benefits as proven by multiple randomised controlled trials(RCT... BACKGROUND Sodium glucose cotransporter-2 inhibitors(SGLT-2i)are a class of drugs with modest antidiabetic efficacy,weight loss effect,and cardiovascular benefits as proven by multiple randomised controlled trials(RCTs).However,real-world data on the comparative efficacy and safety of individual SGLT-2i medications is sparse.AIM To study the comparative efficacy and safety of SGLT-2i using real-world clinical data.METHODS We evaluated the comparative efficacy data of 3 SGLT-2i drugs(dapagliflozin,canagliflozin,and empagliflozin)used for treating patients with type 2 diabetes mellitus.Data on the reduction of glycated hemoglobin(HbA1c),body weight,blood pressure(BP),urine albumin creatinine ratio(ACR),and adverse effects were recorded retrospectively.RESULTS Data from 467 patients with a median age of 64(14.8)years,294(62.96%)males and 375(80.5%)Caucasians were analysed.Median diabetes duration was 16.0(9.0)years,and the duration of SGLT-2i use was 3.6(2.1)years.SGLT-2i molecules used were dapagliflozin 10 mg(n=227;48.6%),canagliflozin 300 mg(n=160;34.3%),and empagliflozin 25 mg(n=80;17.1).Baseline median(interquartile range)HbA1c in mmol/mol were:dapagliflozin-78.0(25.3),canagliflozin-80.0(25.5),and empagliflozin-75.0(23.5)respectively.The respective median HbA1c reduction at 12 months and the latest review(just prior to the study)were:66.5(22.8)&69.0(24.0),67.0(16.3)&66.0(28.0),and 67.0(22.5)&66.5(25.8)respectively(P<0.001 for all comparisons from baseline).Significant improvements in body weight(in kilograms)from baseline to study end were noticed with dapagliflozin-101(29.5)to 92.2(25.6),and canagliflozin 100(28.3)to 95.3(27.5)only.Significant reductions in median systolic and diastolic BP,from 144(21)mmHg to 139(23)mmHg;(P=0.015),and from 82(16)mmHg to 78(19)mmHg;(P<0.001)respectively were also observed.A significant reduction of microalbuminuria was observed with canagliflozin only[ACR 14.6(42.6)at baseline to 8.9(23.7)at the study end;P=0.043].Adverse effects of SGLT-2i were as follows:genital thrush and urinary infection-20(8.8%)&17(7.5%)with dapagliflozin;9(5.6%)&5(3.13%)with canagliflozin;and 4(5%)&4(5%)with empagliflozin.Diabetic ketoacidosis was observed in 4(1.8%)with dapagliflozin and 1(0.63%)with canagliflozin.CONCLUSION Treatment of patients with SGLT-2i is associated with statistically significant reductions in HbA1c,body weight,and better than those reported in RCTs,with low side effect profiles.A review of large-scale real-world data is needed to inform better clinical practice decision making. 展开更多
关键词 Sodium glucose cotransporter-2 inhibitors Empagliflozin Canagliflozin DAPAGLIFLOZIN Type 2 diabetes mellitus Cardiovascular disease Albumin creatinine ratio DIABESITY
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The corrosion characteristic and mechanism of Mg-5Y-1.5Nd-xZn-0.5Zr(x=0,2,4,6 wt.%)alloys in marine atmospheric environment
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作者 Quantong Jiang Dongzhu Lu +2 位作者 Liren Cheng Nazhen Liu Baorong Hou 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第1期139-158,共20页
The microstructure and precipitated phases of as-cast Mg-5Y-1.5Nd-x Zn-0.5Zr(x=0,2,4,6 wt.%)alloys were investigated by optical microscopy,scanning electron microscopy,energy-dispersive spectrometry and X-ray Diffract... The microstructure and precipitated phases of as-cast Mg-5Y-1.5Nd-x Zn-0.5Zr(x=0,2,4,6 wt.%)alloys were investigated by optical microscopy,scanning electron microscopy,energy-dispersive spectrometry and X-ray Diffraction.The exposure corrosion experiment of these magnesium alloys was tested in South China Sea and KEXUE vessel atmospheric environment.The corrosion characteristic and mechanism of magnesium alloys of Mg-5Y-1.5Nd-x Zn-0.5Zr(x=0,2,4,6 wt.%)alloys were analyzed by weight loss rate,corrosion depth,corrosion products and corrosion morphologies.The electrochemical corrosion tests were also measured in the natural seawater.The comprehensive results showed that Mg-5Y-1.5Nd-4Zn-0.5Zr magnesium alloy existed the best corrosion resistance whether in the marine atmospheric environment and natural seawater environment.That depended on the microstructure,type and distribution of precipitated phases in Mg-5Y-1.5Nd-4Zn-0.5Zr magnesium alloy.Sufficient quantity anodic precipitated phases in the microstructure of Mg-5Y-1.5Nd-4Zn-0.5Zr alloy played the key role in the corrosion resistance. 展开更多
关键词 Marine atmospheric environment Exposure corrosion Magnesium alloy corrosion rate corrosion mechanism
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In-situ AFM and quasi-in-situ studies for localized corrosion in Mg-9Al-1Fe-(Gd) alloys under 3.5 wt.% NaCl environment
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作者 Junping Shen Tao Lai +7 位作者 Zheng Yin Yang Chen Kun Wang Hong Yan Honggun Song Ruiliang Liu Chao Luo Zhi Hu 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第3期1170-1185,共16页
Revealing the localized corrosion process of Mg alloy is considered as one of the most significant ways for improving its corrosion resistance.The reliable monitor should be high distinguishability and real-time in li... Revealing the localized corrosion process of Mg alloy is considered as one of the most significant ways for improving its corrosion resistance.The reliable monitor should be high distinguishability and real-time in liquid environment.Herein,Mg-9Al-1Fe and Mg-9Al-1Fe-1Gd alloys were designed to highlight the impact of intermetallic on the corrosion behaviour.In-situ AFM with a special electrolyte circulation system and quasi-in-situ SEM observation were used to monitor the corrosion process of the designed alloys.SEM-EDS and TEM-SAED were applied to identify the intermetallic in the designed alloys,and their volta potentials were measured by SKPFM.According to the real-time and real-space in-situ AFM monitor,the corrosion process consisted of dissolution of anodicα-Mg phase,accumulation of corrosion products around cathodic phase and shedding of some fine cathodic phase.Then,the localized corrosion process of Mg alloy was revealed combined with the results of the monitor of corrosion process and Volta potential difference. 展开更多
关键词 Magnesium Localized corrosion In-situ AFM SKPFM corrosion behaviour.
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Understanding the corrosion and bio-corrosion behaviour of Magnesium composites – a critical review
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作者 Prithivirajan Sekar S.K.Panigrahi 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第3期890-939,共50页
Realising the potential of Magnesium(Mg),several globally leading ventures have invested in the Mg industry,but their relatively poor corrosion resistance is a never ending saga till date.The corrosion and bio-corrosi... Realising the potential of Magnesium(Mg),several globally leading ventures have invested in the Mg industry,but their relatively poor corrosion resistance is a never ending saga till date.The corrosion and bio-corrosion behaviour of Mg has gained research attention and still remains a hot topic in the application of automobile,aerospace and biomedical industries.The intrinsic high electrochemical nature of Mg limits their utilization in diverse application.This scenario has prompted the development of Mg composites with an aim to achieve superior corrosion and bio-corrosion resistance.The present review enlightens the influence of grain size(GS),secondary phase,texture,type of matrix and reinforcement on the corrosion and bio-corrosion behaviour of Mg composites.Firstly,the corrosion and bio-corrosion behaviour of Mg composites manufactured by primary and secondary processing routes are elucidated.Secondly,the comprehensive corrosion and bio-corrosion mechanisms of these Mg composites are proposed.Thirdly,the individual role of GS,texture and corrosive medium on corrosion and bio-corrosion behaviour of Mg composites are clarified and revealed.The challenges encountered,unanswered issues in this field are explained in detail and accordingly the scope for future research is framed.The review is presented from basic concrete background to advanced corrosion mechanisms with an aim of creating interest among the readers like students,researchers and industry experts from various research backgrounds.Indeed,the corrosion and bio-corrosion behaviour of Mg composites are critically reviewed for the first time to:(i)contribute to the body of knowledge,(ii)foster research and development,(iii)make breakthrough,and(iv)create life changing innovations in the field of Mg composite corrosion. 展开更多
关键词 corrosion Bio corrosion Magnesium alloys Magnesium composites Magnesium implants.
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