This paper analyzed the pore structure, quantified the pore fractal dimension, calculated the grading index(GI) of mixed aggregate, and studied the relationship among GI, pore structure, and strength to describe the c...This paper analyzed the pore structure, quantified the pore fractal dimension, calculated the grading index(GI) of mixed aggregate, and studied the relationship among GI, pore structure, and strength to describe the cross-scale characteristics of backfill, which is made from stone powder and cemented tailing. A series of experiments were conducted on stone powder cement tailings backfill(SPCTB). The GI formulas for mixed aggregates, containing stone powder and tailings, were derived based on the Füller theory. The nuclear magnetic resonance(NMR) fractal dimensions of backfills were derived using fractal geometry principles. Compared to the mesopore and macropore fractal dimensions, the correlation between micropore fractal dimension and macro-properties in terms of NMR porosity, pore structure complexity, uniaxial compression strength(UCS), and GI is the most significant. Macropore fractal dimension is generally correlated with UCS and GI and the other properties such as the shape of mixed aggregates also have an impact on fractal dimension. However, mesopore fractal dimension has no obvious relationship with macro-properties. Finally, the relationship between GI and UCS was studied, which contributed to improving backfill’s strength and optimizing gradation.展开更多
In order to further study the reliability of macro evaluation indexes,molecular dynamics (MD) was applied to the evaluation of asphalt binder.Micro evaluation indexes (potential energy,surface free energy,solubility p...In order to further study the reliability of macro evaluation indexes,molecular dynamics (MD) was applied to the evaluation of asphalt binder.Micro evaluation indexes (potential energy,surface free energy,solubility parameter and diffusion coefficient) of asphalt binder in different service phases (virgin,modified,aged and rejuvenated) were simulated.Combined with the variation characteristics of asphalt binder macro evaluation indexes (permeability,ductility,viscosity and softening point) in different service phases,the cross-scale correlation of macro-micro evaluation indexes was explored.The results show that the macro and micro evaluation indexes of asphalt binder have different characteristics in different service phases.The essence of the variation in the properties of asphalt binders is the difference in micro composition.In addition,there is a certain correlation between macro and micro evaluation indexes,which can be described by the gray relation theory.The cross-scale correlation of macro-micro evaluation indexes can provide a certain theoretical basis for the development of asphalt binder.展开更多
Transition metal carbide/nitride cores within MXenes make them considerably useful for ultra-high-temperature reinforcement.However,extensive research on Ti_(3)C_(2)T_(x) MXene has revealed its tendency to undergo a p...Transition metal carbide/nitride cores within MXenes make them considerably useful for ultra-high-temperature reinforcement.However,extensive research on Ti_(3)C_(2)T_(x) MXene has revealed its tendency to undergo a phase transition to TiCy at temperatures above 800℃due to high activity of a superficial Ti atomic layer.Herein,spark plasma sintering of Ti_(3)C_(2)T_(x) and TiC is performed to prevent the Ti_(3)C_(2)T_(x) phase transition at temperatures up to 1900℃through the fabrication of composites at a pressure of 50 MPa.Using a focused ion beam scanning electron microscope to separate layered substances in the composites and examining selected area diffraction spots in a transmission electron microscope enabled identification of non-phase-transitioned MXene.First-principles calculations based on density functional theory indicated the formation of strong chemical bonding interfaces between Ti_(3)C_(2)T_(x) and TiC,which imposed a stability constraint on the Ti atomic layer at the Ti_(3)C_(2)T_(x) surface.Mechanical performance tests,such as three-point bending and fracture toughness analysis,demonstrated that the addition of Ti_(3)C_(2)T_(x) can effectively improve the cross-scale strengthening and toughening of the TiC matrix,providing a new path for designing and developing two-dimensional(2D)carbides cross-scale-enhanced three-dimensional(3D)carbides with the same elements relying on a wide variety of MXenes.展开更多
Mechanical softening behaviors of shale in CO_(2)-water–rock interaction are critical for shale gas exploitation and CO_(2)sequestration.This work investigated the cross-scale mechanical softening of shale triggered ...Mechanical softening behaviors of shale in CO_(2)-water–rock interaction are critical for shale gas exploitation and CO_(2)sequestration.This work investigated the cross-scale mechanical softening of shale triggered by CO_(2)-water–rock interaction.Initially,the mechanical softening of shale following 30 d of exposure to CO_(2)and water was assessed at the rock-forming mineral scale using nanoindentation.The mechanical alterations of rock-forming minerals,including quartz,muscovite,chlorite,and kaolinite,were analyzed and compared.Subsequently,an accurate grain-based modeling(AGBM)was proposed to upscale the nanoindentation results.Numerical models were generated based on the real microstructure of shale derived from TESCAN integrated minerals analyzer(TIMA)digital images.Mechanical parameters of shale minerals determined by nanoindentation served as input material properties for AGBMs.Finally,numerical simulations of uniaxial compression tests were conducted to investigate the impact of mineral softening on the macroscopic Young’s modulus and uniaxial compressive strength(UCS)of shale.The results present direct evidence of shale mineral softening during CO_(2)-water–rock interaction and explore its influence on the upscale mechanical properties of shale.This paper offers a microscopic perspective for comprehending CO_(2)-water-shale interactions and contributes to the development of a cross-scale mechanical model for shale.展开更多
Piezoelectric robots play important roles in the field of micromanipulation, but it is difficult for them to generate steady precision motion at any moment. In order to eliminate the changing inertial force and improv...Piezoelectric robots play important roles in the field of micromanipulation, but it is difficult for them to generate steady precision motion at any moment. In order to eliminate the changing inertial force and improve the motion smoothness, this work proposes a piezoelectric robot with continuous walking gait inspired by ants. The idea is verified with theoretical models and numerical simulation, and the performances are evaluated with experiments. The robot is proven to have the ability to generate 3-DOF(dgeree of freedom) continuous smooth motions with constant speeds. The maximum and minimum smooth velocities have a difference of six orders of magnitude, realizing cross-scale velocity control. Besides, the motion resolution reaches several nanometers with the unlimited workspace, so the cross-scale displacement control can be also obtained. Furthermore, with great robustness against varying loads, the stable actuation capability of the robot is more than 22 times of the self-weight. To sum up,the proposed robot generates cross-scale smooth motion in both aspects of displacement and velocity, so it has good prospects in the applications requiring steady precision motion. The design philosophy and research methods in this work can be valuable references for further advances of micromanipulation robots.展开更多
To predict global climate change and to implement the Kyoto Protocol for stabilizing atmospheric greenhouse gases concentrations require quantifying spatio-temporal variations in the terrestrial carbon sink accurately...To predict global climate change and to implement the Kyoto Protocol for stabilizing atmospheric greenhouse gases concentrations require quantifying spatio-temporal variations in the terrestrial carbon sink accurately. During the past decade multi-scale ecological experiment and observation networks have been established using various new technologies (e.g. controlled environmental facilities, eddy covariance techniques and quantitative remote sensing), and have obtained a large amount of data about terrestrial ecosystem carbon cycle. However, uncertainties in the magnitude and spatio-temporal variations of the terrestrial carbon sink and in understanding the underlying mechanisms have not been reduced significantly. One of the major reasons is that the observations and experiments were conducted at individual scales independently, but it is the interactions of factors and processes at different scales that determine the dynamics of the terrestrial carbon sink. Since experiments and observations are always conducted at specific scales, to understand cross-scale interactions requires mechanistic analysis that is best to be achieved by mechanistic modeling. However, mechanistic ecosystem models are mainly based on data from single-scale experiments and observations and hence have no capacity to simulate mechanistic cross-scale interconnection and interactions of ecosystem processes. New-generation mechanistic ecosystem models based on new ecological theoretical framework are needed to quantify the mechanisms from micro-level fast eco-physiological responses to macro-level slow acclimation in the pattern and structure in disturbed ecosystems. Multi-scale data-model fusion is a recently emerging approach to assimilate multi-scale observational data into mechanistic, dynamic modeling, in which the structure and parameters of mechanistic models for simulating cross-scale interactions are optimized using multi-scale observational data. The models are validated and evaluated at different spatial and temporal scales and real-time observational data are assimilated continuously into dynamic modeling for predicting and forecasting ecosystem changes realistically. in summary, a breakthrough in terrestrial carbon sink research requires using approaches of multi-scale observations and cross-scale modeling to understand and quantify interconnections and interactions among ecosystem processes at different scales and their controls over ecosystem carbon cycle.展开更多
A simultaneous prediction of macroscopic deformation and microstructure evolution is critical for un-derstanding the deformation mechanism of components.In this work,the hydro-bulging process of 2219 aluminum alloy sh...A simultaneous prediction of macroscopic deformation and microstructure evolution is critical for un-derstanding the deformation mechanism of components.In this work,the hydro-bulging process of 2219 aluminum alloy sheet was investigated using cross-scale numerical modeling,in which the macroscopic finite element method(FEM)and crystal plasticity finite element method(CPFEM)were combined.The calculated texture evolution exhibits good agreement with the experimental results,and the stress er-ror between the two scales is generally small.The effects of different strain states on texture evolution and slip mode are further discussed.As the strain ratioηincreases,the volume fractions of the initial Rotated Copper texture component andγ-Fiber texture component decrease significantly,which tend to be stabilized at P texture component.The initial Rotated Cube texture component is inclined to rotate towards the Cube texture component,while the volume fraction of this orientation is relatively stable.The lower strain ratio can considerably enhance the activity of more equivalent slip systems,promoting a more uniform strain distribution over grains.The difficulty of grain deformation changes as the lat-tice rotates.The grain with easy-to-deform orientation can gradually rotate to a stable orientation during plastic deformation,which has a lower Schmid factor.展开更多
The digital twin shop-floor has received much attention from the manufacturing industry as it is an important way to upgrade the shop-floor digitally and intelligently.As a key part of the shop-floor,humans'high a...The digital twin shop-floor has received much attention from the manufacturing industry as it is an important way to upgrade the shop-floor digitally and intelligently.As a key part of the shop-floor,humans'high autonomy and uncertainty leads to the difficulty in digital twin modeling of human behavior.Therefore,the modeling system for cross-scale human behavior in digital twin shop-floors was developed,powered by the data fusion of macro-behavior and micro-behavior virtual models.Shop-floor human macro-behavior mainly refers to the role of the human and their real-time position.Shop-floor micro-behavior mainly refers to real-time human limb posture and production behavior at their workstation.In this study,we reviewed and summarized a set of theoretical systems for cross-scale human behavior modeling in digital twin shop-floors.Based on this theoretical system,we then reviewed modeling theory and technology from macro-behavior and micro-behavior aspects to analyze the research status of shop-floor human behavior modeling.Lastly,we discuss and offer opinion on the application of cross-scale human behavior modeling in digital twin shop-floors.Cross-scale human behavior modeling is the key for realizing closed-loop interactive drive of human behavior in digital twin shop-floors.展开更多
The finite volume method (FVM) and the lattice Boltzmann method (LBM) are coupled with each other to construct a new cross-scaling method to deal with the porous flow problem. To check the effectiveness of our dev...The finite volume method (FVM) and the lattice Boltzmann method (LBM) are coupled with each other to construct a new cross-scaling method to deal with the porous flow problem. To check the effectiveness of our developed cross-scaling LBM-FVM, the above mentioned problem is also solved by the well known LBM-LBM. Based on the data checking of the published data and the results of LBM-FVM and LBM-LBM, good agreement is observed.展开更多
This case study examines how the Hampton Roads Sea Level Rise Preparedness and Resilience Intergovernmental Planning Pilot Project, a whole-of-government and whole-of-community approach to planning for and adapting to...This case study examines how the Hampton Roads Sea Level Rise Preparedness and Resilience Intergovernmental Planning Pilot Project, a whole-of-government and whole-of-community approach to planning for and adapting to sea level rise, addressed coastal resilience in a southeastern Virginia watershed that spans multiple jurisdictions. Meeting the challenge of sea level rise requires that actors across multiple sectors—citizens, community organizations, industry and government—understand the risks and work together to make critical decisions regarding adaptation strategies and actions. The case study area includes Little Creek Amphibious Base, which is bordered by the cities of Norfolk and Virginia Beach. Adaptation responses to sea level rise by the military base and the local governments will impact each other and the residents of the area, but no cooperative agreements are in place for a joint or collaborative response. This case study examines public and private infrastructure at risk, the infrastructure interdependencies, and mechanisms for providing collaborative solutions. Engagement of area residents and other stakeholders is also integral to the process of adaptation, which includes educating about sea level rise risk and provides a mechanism for social learning that enables stakeholders to participate in critical adaptation decisions. The case study demonstrates a method to improve resiliency in the case study area and inform a regional, multi-sectoral response to sea level rise adaptation strategies.展开更多
电子显微成像技术的快速发展使得对完整细胞、组织乃至整个机体进行高分辨三维结构解析研究成为可能,这些可进行大尺度生物样品三维结构研究的电子显微成像技术统称为体电子显微学技术(volume electron microscopy,vEM)。近年来,v EM在...电子显微成像技术的快速发展使得对完整细胞、组织乃至整个机体进行高分辨三维结构解析研究成为可能,这些可进行大尺度生物样品三维结构研究的电子显微成像技术统称为体电子显微学技术(volume electron microscopy,vEM)。近年来,v EM在研究尺度、分辨率、吞吐量和易用性等方面发展迅速,在整个生命科学领域的应用呈爆炸式增长,该技术因此被《自然》(Nature)评为2023年最值得关注的七项前沿技术之一。然而,vEM相关技术的发展和应用在国内起步较晚,亟待进一步推广。本综述涵盖了vEM的发展历程、技术分类、样品制备、数据收集、图像处理等全方位的内容,便于生命科学、医学等领域研究人员去了解、学习、应用和进一步发展该技术。展开更多
基金Project(41672298)supported by the National Natural Science Foundation of ChinaProject(2017YFC0602901)supported by the National Key Research and Development Program of China。
文摘This paper analyzed the pore structure, quantified the pore fractal dimension, calculated the grading index(GI) of mixed aggregate, and studied the relationship among GI, pore structure, and strength to describe the cross-scale characteristics of backfill, which is made from stone powder and cemented tailing. A series of experiments were conducted on stone powder cement tailings backfill(SPCTB). The GI formulas for mixed aggregates, containing stone powder and tailings, were derived based on the Füller theory. The nuclear magnetic resonance(NMR) fractal dimensions of backfills were derived using fractal geometry principles. Compared to the mesopore and macropore fractal dimensions, the correlation between micropore fractal dimension and macro-properties in terms of NMR porosity, pore structure complexity, uniaxial compression strength(UCS), and GI is the most significant. Macropore fractal dimension is generally correlated with UCS and GI and the other properties such as the shape of mixed aggregates also have an impact on fractal dimension. However, mesopore fractal dimension has no obvious relationship with macro-properties. Finally, the relationship between GI and UCS was studied, which contributed to improving backfill’s strength and optimizing gradation.
基金Funded by the Fundamental Research Funds for the Central Universities (No. 2572021AW10)。
文摘In order to further study the reliability of macro evaluation indexes,molecular dynamics (MD) was applied to the evaluation of asphalt binder.Micro evaluation indexes (potential energy,surface free energy,solubility parameter and diffusion coefficient) of asphalt binder in different service phases (virgin,modified,aged and rejuvenated) were simulated.Combined with the variation characteristics of asphalt binder macro evaluation indexes (permeability,ductility,viscosity and softening point) in different service phases,the cross-scale correlation of macro-micro evaluation indexes was explored.The results show that the macro and micro evaluation indexes of asphalt binder have different characteristics in different service phases.The essence of the variation in the properties of asphalt binders is the difference in micro composition.In addition,there is a certain correlation between macro and micro evaluation indexes,which can be described by the gray relation theory.The cross-scale correlation of macro-micro evaluation indexes can provide a certain theoretical basis for the development of asphalt binder.
基金the financial support from the National Natural Science Foundation of China(Grant Nos.11872171,91016014,and 51872062)Fundamental Research Funds for the Central Universities(Grant No.B200202117)。
文摘Transition metal carbide/nitride cores within MXenes make them considerably useful for ultra-high-temperature reinforcement.However,extensive research on Ti_(3)C_(2)T_(x) MXene has revealed its tendency to undergo a phase transition to TiCy at temperatures above 800℃due to high activity of a superficial Ti atomic layer.Herein,spark plasma sintering of Ti_(3)C_(2)T_(x) and TiC is performed to prevent the Ti_(3)C_(2)T_(x) phase transition at temperatures up to 1900℃through the fabrication of composites at a pressure of 50 MPa.Using a focused ion beam scanning electron microscope to separate layered substances in the composites and examining selected area diffraction spots in a transmission electron microscope enabled identification of non-phase-transitioned MXene.First-principles calculations based on density functional theory indicated the formation of strong chemical bonding interfaces between Ti_(3)C_(2)T_(x) and TiC,which imposed a stability constraint on the Ti atomic layer at the Ti_(3)C_(2)T_(x) surface.Mechanical performance tests,such as three-point bending and fracture toughness analysis,demonstrated that the addition of Ti_(3)C_(2)T_(x) can effectively improve the cross-scale strengthening and toughening of the TiC matrix,providing a new path for designing and developing two-dimensional(2D)carbides cross-scale-enhanced three-dimensional(3D)carbides with the same elements relying on a wide variety of MXenes.
基金supported by the China Postdoctoral Science Foundation(Grant Nos.2023TQ0247 and 2023M732715)the Postdoctoral Fellowship Program(Grade B)of China Postdoctoral Science Foundation(Grant No.GZB20230544)the National Natural Science Foundation of China(Grant Nos.U21A20153 and 41841018).
文摘Mechanical softening behaviors of shale in CO_(2)-water–rock interaction are critical for shale gas exploitation and CO_(2)sequestration.This work investigated the cross-scale mechanical softening of shale triggered by CO_(2)-water–rock interaction.Initially,the mechanical softening of shale following 30 d of exposure to CO_(2)and water was assessed at the rock-forming mineral scale using nanoindentation.The mechanical alterations of rock-forming minerals,including quartz,muscovite,chlorite,and kaolinite,were analyzed and compared.Subsequently,an accurate grain-based modeling(AGBM)was proposed to upscale the nanoindentation results.Numerical models were generated based on the real microstructure of shale derived from TESCAN integrated minerals analyzer(TIMA)digital images.Mechanical parameters of shale minerals determined by nanoindentation served as input material properties for AGBMs.Finally,numerical simulations of uniaxial compression tests were conducted to investigate the impact of mineral softening on the macroscopic Young’s modulus and uniaxial compressive strength(UCS)of shale.The results present direct evidence of shale mineral softening during CO_(2)-water–rock interaction and explore its influence on the upscale mechanical properties of shale.This paper offers a microscopic perspective for comprehending CO_(2)-water-shale interactions and contributes to the development of a cross-scale mechanical model for shale.
基金supported by the National Natural Science Foundation of China (Grant Nos. U1913215 and 51975144)。
文摘Piezoelectric robots play important roles in the field of micromanipulation, but it is difficult for them to generate steady precision motion at any moment. In order to eliminate the changing inertial force and improve the motion smoothness, this work proposes a piezoelectric robot with continuous walking gait inspired by ants. The idea is verified with theoretical models and numerical simulation, and the performances are evaluated with experiments. The robot is proven to have the ability to generate 3-DOF(dgeree of freedom) continuous smooth motions with constant speeds. The maximum and minimum smooth velocities have a difference of six orders of magnitude, realizing cross-scale velocity control. Besides, the motion resolution reaches several nanometers with the unlimited workspace, so the cross-scale displacement control can be also obtained. Furthermore, with great robustness against varying loads, the stable actuation capability of the robot is more than 22 times of the self-weight. To sum up,the proposed robot generates cross-scale smooth motion in both aspects of displacement and velocity, so it has good prospects in the applications requiring steady precision motion. The design philosophy and research methods in this work can be valuable references for further advances of micromanipulation robots.
基金This study was supported by the China's Ministry of Science and Technology(Grant No.G2002CB412507)the National Natural Science Foundation of China(Grant No.40425103).
文摘To predict global climate change and to implement the Kyoto Protocol for stabilizing atmospheric greenhouse gases concentrations require quantifying spatio-temporal variations in the terrestrial carbon sink accurately. During the past decade multi-scale ecological experiment and observation networks have been established using various new technologies (e.g. controlled environmental facilities, eddy covariance techniques and quantitative remote sensing), and have obtained a large amount of data about terrestrial ecosystem carbon cycle. However, uncertainties in the magnitude and spatio-temporal variations of the terrestrial carbon sink and in understanding the underlying mechanisms have not been reduced significantly. One of the major reasons is that the observations and experiments were conducted at individual scales independently, but it is the interactions of factors and processes at different scales that determine the dynamics of the terrestrial carbon sink. Since experiments and observations are always conducted at specific scales, to understand cross-scale interactions requires mechanistic analysis that is best to be achieved by mechanistic modeling. However, mechanistic ecosystem models are mainly based on data from single-scale experiments and observations and hence have no capacity to simulate mechanistic cross-scale interconnection and interactions of ecosystem processes. New-generation mechanistic ecosystem models based on new ecological theoretical framework are needed to quantify the mechanisms from micro-level fast eco-physiological responses to macro-level slow acclimation in the pattern and structure in disturbed ecosystems. Multi-scale data-model fusion is a recently emerging approach to assimilate multi-scale observational data into mechanistic, dynamic modeling, in which the structure and parameters of mechanistic models for simulating cross-scale interactions are optimized using multi-scale observational data. The models are validated and evaluated at different spatial and temporal scales and real-time observational data are assimilated continuously into dynamic modeling for predicting and forecasting ecosystem changes realistically. in summary, a breakthrough in terrestrial carbon sink research requires using approaches of multi-scale observations and cross-scale modeling to understand and quantify interconnections and interactions among ecosystem processes at different scales and their controls over ecosystem carbon cycle.
基金financially supported by the National Natural Science Foundation of China(No.52275322)the Heilongjiang Touyan Team(No.HITTY-20190015).
文摘A simultaneous prediction of macroscopic deformation and microstructure evolution is critical for un-derstanding the deformation mechanism of components.In this work,the hydro-bulging process of 2219 aluminum alloy sheet was investigated using cross-scale numerical modeling,in which the macroscopic finite element method(FEM)and crystal plasticity finite element method(CPFEM)were combined.The calculated texture evolution exhibits good agreement with the experimental results,and the stress er-ror between the two scales is generally small.The effects of different strain states on texture evolution and slip mode are further discussed.As the strain ratioηincreases,the volume fractions of the initial Rotated Copper texture component andγ-Fiber texture component decrease significantly,which tend to be stabilized at P texture component.The initial Rotated Cube texture component is inclined to rotate towards the Cube texture component,while the volume fraction of this orientation is relatively stable.The lower strain ratio can considerably enhance the activity of more equivalent slip systems,promoting a more uniform strain distribution over grains.The difficulty of grain deformation changes as the lat-tice rotates.The grain with easy-to-deform orientation can gradually rotate to a stable orientation during plastic deformation,which has a lower Schmid factor.
基金This work was supported by the National Key Research and Development Program,China[2020YFB1708400]the National Defense Fundamental Research Program,China[JCKY2020210B006,JCKY2017204B053].
文摘The digital twin shop-floor has received much attention from the manufacturing industry as it is an important way to upgrade the shop-floor digitally and intelligently.As a key part of the shop-floor,humans'high autonomy and uncertainty leads to the difficulty in digital twin modeling of human behavior.Therefore,the modeling system for cross-scale human behavior in digital twin shop-floors was developed,powered by the data fusion of macro-behavior and micro-behavior virtual models.Shop-floor human macro-behavior mainly refers to the role of the human and their real-time position.Shop-floor micro-behavior mainly refers to real-time human limb posture and production behavior at their workstation.In this study,we reviewed and summarized a set of theoretical systems for cross-scale human behavior modeling in digital twin shop-floors.Based on this theoretical system,we then reviewed modeling theory and technology from macro-behavior and micro-behavior aspects to analyze the research status of shop-floor human behavior modeling.Lastly,we discuss and offer opinion on the application of cross-scale human behavior modeling in digital twin shop-floors.Cross-scale human behavior modeling is the key for realizing closed-loop interactive drive of human behavior in digital twin shop-floors.
基金supported by the National Nature Science Foundation of China (10932010,51176172,11072220)the Research Grants Council of the Government of the HKSAR (PolyU5172/02E,PolyU5221/05E)
文摘The finite volume method (FVM) and the lattice Boltzmann method (LBM) are coupled with each other to construct a new cross-scaling method to deal with the porous flow problem. To check the effectiveness of our developed cross-scaling LBM-FVM, the above mentioned problem is also solved by the well known LBM-LBM. Based on the data checking of the published data and the results of LBM-FVM and LBM-LBM, good agreement is observed.
文摘This case study examines how the Hampton Roads Sea Level Rise Preparedness and Resilience Intergovernmental Planning Pilot Project, a whole-of-government and whole-of-community approach to planning for and adapting to sea level rise, addressed coastal resilience in a southeastern Virginia watershed that spans multiple jurisdictions. Meeting the challenge of sea level rise requires that actors across multiple sectors—citizens, community organizations, industry and government—understand the risks and work together to make critical decisions regarding adaptation strategies and actions. The case study area includes Little Creek Amphibious Base, which is bordered by the cities of Norfolk and Virginia Beach. Adaptation responses to sea level rise by the military base and the local governments will impact each other and the residents of the area, but no cooperative agreements are in place for a joint or collaborative response. This case study examines public and private infrastructure at risk, the infrastructure interdependencies, and mechanisms for providing collaborative solutions. Engagement of area residents and other stakeholders is also integral to the process of adaptation, which includes educating about sea level rise risk and provides a mechanism for social learning that enables stakeholders to participate in critical adaptation decisions. The case study demonstrates a method to improve resiliency in the case study area and inform a regional, multi-sectoral response to sea level rise adaptation strategies.
文摘电子显微成像技术的快速发展使得对完整细胞、组织乃至整个机体进行高分辨三维结构解析研究成为可能,这些可进行大尺度生物样品三维结构研究的电子显微成像技术统称为体电子显微学技术(volume electron microscopy,vEM)。近年来,v EM在研究尺度、分辨率、吞吐量和易用性等方面发展迅速,在整个生命科学领域的应用呈爆炸式增长,该技术因此被《自然》(Nature)评为2023年最值得关注的七项前沿技术之一。然而,vEM相关技术的发展和应用在国内起步较晚,亟待进一步推广。本综述涵盖了vEM的发展历程、技术分类、样品制备、数据收集、图像处理等全方位的内容,便于生命科学、医学等领域研究人员去了解、学习、应用和进一步发展该技术。